CIC Gene
protein-coding GIFtS: 56
GCID: GC19P042772
|
|
capicua homolog (Drosophila)(Previous name: capicua (Drosophila) homolog )
| |
Aliases
for CIC gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Capicua Homolog (Drosophila)1 2 | | KIAA03061 3 5 | | Capicua (Drosophila) Homolog1 | | Protein Capicua Homolog2 |
Export aliases for CIC gene to outside databasesPrevious GC identifers: GC19P043435 GC19P043180 GC19P047454 GC19P047480 GC19P042788 GC19P039219 |
Summaries
for CIC gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: CIC_HUMAN, Q96RK0Function: Transcriptional repressor which may play a role in development of the central nervous system (CNS)
Gene Wiki entry for CIC
|
Genomic Views
for CIC gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CIC gene promoter:
CREB TBP AREB6 deltaCREB c-Myb Ik-3 Roaz GATA-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for CIC
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CIC |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.2 Ensembl cytogenetic band: 19q13.2 HGNC cytogenetic band: 19q13.2CIC Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P042772: view genomic region
(about GC identifiers)
Start:
|
42,772,689 bp from pter |
End:
|
42,799,949 bp from pter |
Size:
|
27,261 bases |
Orientation:
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plus strand |
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Proteins
for CIC gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CIC_HUMAN, Q96RK0 (See
protein sequence)Recommended Name: Protein capicua homolog Size: 1608 amino acids; 163820 Da
Subunit: Interacts with ATXN1 and ATXN1L (By similarity)
Subcellular location: Nucleus (Potential)
Miscellaneous: Expressed in medulloblastoma, a pediatric brain tumor which may arise from the granule cell lineage
Sequence caution: Sequence=AAD11988.1; Type=Erroneous gene model prediction;
Secondary accessions: Q7LGI1 Q9UEG5 Q9Y6T1Explore the universe of human proteins at neXtProt for CIC: NX_Q96RK0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96RK0
CIC Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055940.3
ENSEMBL proteins: ENSP00000459719 ENSP00000459704 ENSP00000160740 ENSP00000458663 ENSP00000458543 ENSP00000459011 ENSP00000460230
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
CIC for ontologies About GeneDecksing
CIC Antibody Products:
Assay Products for CIC: |
Protein
Domains /
Families
for CIC gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CIC for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96RK0ProtoNet protein and cluster: Q96RK0 1 Blocks protein family: IPB002345 Lipocalin signature
UniProtKB/Swiss-Prot: CIC_HUMAN, Q96RK0Similarity: Contains 1 HMG box DNA-binding domain |
Function
for CIC gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CIC_HUMAN, Q96RK0Function: Transcriptional repressor which may play a role in development of the central nervous system (CNS)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CIC (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CIC
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for CIC | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CIC |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CIC |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
CIC for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for CIC:
Animal Models:
5 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Cic):
CIC for phenotypes About GeneDecksing
|
Pathways & Interactions
for CIC gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CIC
STRING Interaction
Network Preview (showing 5 interactants - click image to see 16)
5/28 Interacting proteins for CIC (Q96RK01, 2, 3 ENSP000001607404) via UniProtKB, MINT, STRING, and/or I2D (see all 28)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| ATXN1 | P542531, 2, 3, ENSP000002447694 | EBI-945857,EBI-930964 MINT-2870723 MINT-2862865 MINT-2870685 MINT-2870704 MINT-2870742 I2D:
score=3 STRING: ENSP00000244769 | | GABPB1 | Q065472, 3, ENSP000003702594 | MINT-2859081 I2D:
score=3 STRING: ENSP00000370259 | | SETD2 | Q9BYW22, 3, ENSP000003867594 | MINT-2872285 I2D:
score=3 STRING: ENSP00000386759 | | CSNK2B | P678702, 3 | MINT-8253154 I2D:
score=2 | | PLK1 | P533502, 3 | MINT-8266843 I2D:
score=2 |
About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
CIC for ontologies About GeneDecksing
|
Drugs & Compounds
for CIC gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CIC
Search CenterWatch for drugs/clinical trials and news about CIC
|
Transcripts
for CIC gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CIC gene: NM_015125.3 Unigene Cluster for CIC: Capicua homolog (Drosophila) Hs.388236 [show with all ESTs]Unigene Representative Sequence: NM_0151259 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000572681 ENST00000571942 ENST00000575839 ENST00000160740(uc002otf.1)
ENST00000575354 ENST00000573349 ENST00000576505 ENST00000575287 ENST00000571033
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CIC (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CIC
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CIC (NM_015125) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CIC | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CIC |
Additional cDNA sequence: AB002304.1 AF363689.1 AK025939.1 6 DOTS entries: DT.214783 DT.100714345 DT.65285627 DT.95272251 DT.121501873 DT.100646739 24/215 AceView cDNA sequences (see all 215): BQ721422 AI521565 AA364034 AA419377 BQ279057 BQ100678 BU542367 BU542377 BQ286626 BQ100954 BM680202 BQ086251 AI199740 CB321879 BQ707646 CK823031 BM669888 AL045450 AA632342 AW055303 BF971330 BQ893906 BM352665 BM553258
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for CIC About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16a | · | 16b | · | 16c | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CIC
|
Expression
for CIC gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CIC expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGCAATATTT
About this image
See CIC Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CIC
SOURCE GeneReport for Unigene cluster: Hs.388236
UniProtKB/Swiss-Prot: CIC_HUMAN, Q96RK0Tissue specificity: Expressed in fetal brain
SABiosciences Custom PCR Arrays for CIC
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CIC
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CIC | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CIC | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CIC | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CIC |
Orthologs
for CIC gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CIC gene from 3/12 species (see all 12) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Cic1 , 5 |
capicua homolog (Drosophila)1, 5 |
88.04(n)1
92.56(a)1 |
|
7 (13.73 cM)5
717221 NM_001110131.11 NP_001103601.11
252677045 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.138632 |
Transcribed sequence with moderate similarity to protein more |
76.39(n) |
|
CD591325.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
cic3 |
negative regulation of transcription
transcription more |
63(a) |
|
3 92E2 -- |
ENSEMBL Gene Tree for CIC (if available)
TreeFam Gene Tree for CIC (if available) |
Paralogs
for CIC gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CIC gene
- BBX2
7 SIMAP similar genes for CIC using alignment to 7 protein entries: CIC_HUMAN (see all proteins):CIC/DUX4 fusion BBX TCF7L2 HBP1 soxB TCF7
SRY
CIC for paralogs About GeneDecksing
5/20 Pseudogenes.org Pseudogenes for CIC (see all 20)
PGOHUM00000238422 PGOHUM00000244468 PGOHUM00000244554 PGOHUM00000245214 PGOHUM00000245217
|
Genomic Variants
for CIC gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CIC (42772689 - 42799949 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for CIC
2 CNVs: 5445 73375
Human Gene Mutation Database (HGMD): CIC
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CIC |
|
Disorders
/ Diseases
for CIC gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CIC for disorders About GeneDecksing
OMIM gene information: 612082
OMIM disorders: --
6  diseases for CIC: About MalaCardspityriasis versicolor oligodendroglioma medulloblastoma ataxia
sarcoma neuronitis
1 disease from the University of Copenhagen DISEASES database for CIC:Pityriasis versicolor Human Genome Epidemiology (HuGE) Navigator: CIC (13 documents)
Export disorders for CIC gene to outside databases
|
Publications
for CIC gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CIC gene, integrated from 9 sources (see all 26):
(articles sorted by number of sources associating them with CIC) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- CIC, a gene involved in cerebellar development and ErbB signaling, is significantly expressed in medulloblastomas. (PubMed id 15981098)1, 2, 3 Lee C.J....Scotting P.J. (2005)
- CIC, a member of a novel subfamily of the HMG-box superfamily, is transiently expressed in developing granule neurons. (PubMed id 12393275)1, 2, 3 Lee C.-J.... Scotting P.J. (2002)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
- Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841)1, 2 Nagase T.... Ohara O. (1997)
- Concurrent CIC mutations, IDH mutations, and 1p/19q l oss distinguish oligodendrogliomas from other cancers. (PubMed id 22072542)1 Yip S....Marra M.A. (2012)
- CIC and FUBP1 mutations in oligodendrogliomas, oligoas trocytomas and astrocytomas. (PubMed id 22588899)1 Sahm F....Hartmann C. (2012)
- Mutations in CIC and FUBP1 contribute to human oligod endroglioma. (PubMed id 21817013)1 Bettegowda C....Kinzler K.W. (2011)
- A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
- ATP induces conformational changes in the carboxyl-te rminal region of ClC-5. (PubMed id 21173145)1 Wellhauser L....Bear C.E. (2011)
|
External Searches for CIC gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CIC gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CIC gene
(According to HUGE)
About This Section
| |
Specialized Databases showing CIC gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CIC | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CIC gene:
Search GeneIP for patents involving CIC
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CIC gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for CIC | | OriGene shRNA RFP for CIC | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CIC | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CIC | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CIC | | OriGene 3'-UTR Clone for CIC | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CIC | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CIC | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CIC | | OriGene Custom Protein Services for CIC | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CIC | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CIC | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CIC | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CIC | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CIC | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CIC |
| |
 |  |  |  | |
| | | | Search Tocris compounds for CIC |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | CIC Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CIC |
|  |  |  | | | | ThermoFisher Antibodies for CIC |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CIC |
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