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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CIAO1 Gene

protein-coding   GIFtS: 54
GCID: GC02P096931

cytosolic iron-sulfur protein assembly 1

(Previous names: WD repeat domain 39, cytosolic iron-sulfur protein assembly...)
(Previous symbol: WDR39)
 Explore 1 disease affiliated with
CIAO1 via our new
 Human Malady Compendium 
Biological research products
for CIAO1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Cytosolic Iron-Sulfur Protein Assembly 11 2     Cytosolic Iron-Sulfur Protein Assembly 1 Homolog (S. Cerevisiae)1
WDR391 2 3 5     Cytosolic Iron-Sulfur Protein Assembly 1 Homolog2
CIA11 2     Probable Cytosolic Iron-Sulfur Protein Assembly Protein CIAO12
WD Repeat Domain 391 2     WD40 Protein Ciao12
WD Repeat-Containing Protein 392 3     

External Ids:    HGNC: 142801   Entrez Gene: 93912   Ensembl: ENSG000001440217   OMIM: 6043335   UniProtKB: O760713   

Export aliases for CIAO1 gene to outside databases

Previous GC identifers: GC02P094803 GC02P095386 GC02P096399 GC02P096416 GC02P096353 GC02P096295 GC02P090893


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: CIAO1_HUMAN, O76071
Function: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that
mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically
modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a
role in chromosome segregation

Gene Wiki entry for CIAO1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_022171.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CIAO1 gene promoter:
         GR   E2F-4   E2F-3a   E2F-5   GR-beta   E2F-2   E2F   E2F-1   GR-alpha   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCIAO1 promoter sequence
   Search SABiosciences Chromatin IP Primers for CIAO1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CIAO1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q11.2   Ensembl cytogenetic band:  2q11.2   HGNC cytogenetic band: 2q11.1-q11.2

CIAO1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CIAO1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P096931:  view genomic region     (about GC identifiers)

Start:
96,931,870 bp from pter      End:
96,939,917 bp from pter
Size:
8,048 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CIAO1_HUMAN, O76071 (See protein sequence)
Recommended Name: Probable cytosolic iron-sulfur protein assembly protein CIAO1  
Size: 339 amino acids; 37840 Da
Subunit: Component of the CIA complex. Component of the MMXD complex, which includes CIAO1, ERCC2, FAM96B, MMS19 and
SLC25A5. Interacts with WT1. Interacts with FAM96A
Miscellaneous: 'Ciao' means 'bridge' in Chinese
1 PDB 3D structure from and Proteopedia for CIAO1:
3FM0 (3D)    
Secondary accessions: A0MNN9 Q53FM5

Explore the universe of human proteins at neXtProt for CIAO1: NX_O76071

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O76071

  • CIAO1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_004795.1  
    ENSEMBL proteins: 
     ENSP00000418287  
    Reactome Protein details: O76071
    Human Recombinant Protein Products: 
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    OriGene Protein Over-expression Lysate: CIAO1
    OriGene Custom Protein Services for CIAO1 
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    Novus Biologicals CIAO1 Proteins
    Novus Biologicals CIAO1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for CIAO1

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0071817MMXD complex IDA--
    GO:0097361CIA complex IDA--


    CIAO1 for ontologies           About GeneDecksing



    CIAO1 Antibody Products: 
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    ThermoFisher Antibodies for CIAO1

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    Uscn ELISAs and CLIAs for CIAO1


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    CIAO1 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR019775 WD40_repeat_CS
     IPR001680 WD40_repeat
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry O76071

    ProtoNet protein and cluster: O76071

    1 Blocks protein family: IPB001680 G-protein beta WD-40 repeat signature

    UniProtKB/Swiss-Prot: CIAO1_HUMAN, O76071
    Similarity: Belongs to the WD repeat CIA1 family
    Similarity: Contains 7 WD repeats


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: CIAO1_HUMAN, O76071
    Function: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that
    mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically
    modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a
    role in chromosome segregation

         Genatlas biochemistry entry for CIAO1:
    functional modulator of the transcriptional activation function Wilms tumor suppressor gene (WT1),ubiquitously
    expressed,evolutionarily conserved

    miRNA
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    miRTarBase miRNAs that target CIAO1:
    hsa-let-7b (MIRT005218)

    OriGene 3'-UTR Clone: CIAO1
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CIAO1
    8/19 QIAGEN miScript miRNA Assays for microRNAs that regulate CIAO1 (see all 19):
    hsa-miR-623 hsa-miR-200a hsa-miR-138-2* hsa-miR-340 hsa-miR-550a* hsa-miR-1273d hsa-miR-4314 hsa-miR-141
    SwitchGear 3'UTR luciferase reporter plasmidCIAO1 3' UTR sequence
    Inhib. RNA
    Products:
        
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CIAO1 (see all 7)
    OriGene shRNA RFP: CIAO1
    OriGene siRNA: CIAO1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CIAO1

    Gene Editing
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    Clone
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    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: CIAO1 (NM_004804)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CIAO1 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CIAO1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Cytosolic Iron-sulfur Cluster Assembly
    Cytosolic Iron-sulfur Cluster Assembly1.00
    CIA Targeting Complex Transfers 4Fe-4S Cluster to Apoproteins0.77
    2Metabolism
    Metabolism1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    3        Reactome Pathways for CIAO1
        Cytosolic Iron-sulfur Cluster Assembly
    Metabolism
    CIA Targeting Complex Transfers 4Fe-4S Cluster to Apoproteins



    CIAO1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CIAO1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/78 Interacting proteins for CIAO1 (O760712, 3 ENSP000004182874) via UniProtKB, MINT, STRING, and/or I2D (see all 78)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCDC7Q96M832, 3, ENSP000002776574MINT-66303 I2D: score=4 STRING: ENSP00000277657
    FAM96BQ9Y3D02, 3, ENSP000003874714MINT-66428 I2D: score=17 STRING: ENSP00000387471
    FAM96AQ9H5X12, 3, ENSP000003000304MINT-68371 I2D: score=5 STRING: ENSP00000300030
    GOLM1Q8NBJ42, 3, ENSP000003733634MINT-64968 I2D: score=4 STRING: ENSP00000373363
    MMS19Q96T763, ENSP000003598184I2D: score=6 STRING: ENSP00000359818
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006357regulation of transcription from RNA polymerase II promoter TAS9556563
    GO:0007059chromosome segregation IEA--
    GO:0008284positive regulation of cell proliferation TAS9556563
    GO:0016226iron-sulfur cluster assembly IGI17937914


    CIAO1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CIAO1
    Search CenterWatch for drugs/clinical trials and news about CIAO1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CIAO1 gene: 
    NM_004804.2  

    Unigene Cluster for CIAO1:

    Cytosolic iron-sulfur protein assembly 1
    Hs.12109  [show with all ESTs]
    Unigene Representative Sequence: NM_004804
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000488633 ENST00000469320 ENST00000272402(uc002svs.3) ENST00000491394


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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CIAO1
    8/19 QIAGEN miScript miRNA Assays for microRNAs that regulate CIAO1 (see all 19):
    hsa-miR-623 hsa-miR-200a hsa-miR-138-2* hsa-miR-340 hsa-miR-550a* hsa-miR-1273d hsa-miR-4314 hsa-miR-141
    SwitchGear 3'UTR luciferase reporter plasmidCIAO1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CIAO1 (see all 7)
    OriGene shRNA RFP: CIAO1
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CIAO1
    Clone
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    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: CIAO1 (NM_004804)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CIAO1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CIAO1 
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CIAO1
      Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CIAO1

    Additional cDNA sequence: 

    AF086118.1 AK056423.1 AK092687.1 AK098406.1 AK124703.1 AK223257.1 AK299503.1 AK315568.1 
    BC001395.2 BC032812.1 CR456802.1 EF011618.1 U63810.1 

    18 DOTS entries:

    DT.316478  DT.100823188  DT.100823179  DT.75188842  DT.97854170  DT.120996302  DT.120996334  DT.91864398 
    DT.120996346  DT.97777837  DT.100666625  DT.100823169  DT.65284707  DT.86858981  DT.95166140  DT.100679351 
    DT.97807769  DT.99965041 

    24/295 AceView cDNA sequences (see all 295):

    BG222419 BM823662 BC001395 AI339732 BI518418 AL553612 BG251014 BQ277767 
    R72718 CR593125 AV705408 AI383487 BM479349 AF086118 AW157492 BX419759 
    AI678785 AU105665 CA421340 AW467393 BG611080 AK092687 BE221405 BM994764 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for CIAO1 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8a · 8b
    SP1:                          -                                         -           -                     
    SP2:                          -                                         -                                 
    SP3:                          -                                         -     -     -     -               
    SP4:                          -     -                                                                     
    SP5:                                                                                                      


    ECgene alternative splicing isoforms for CIAO1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CIAO1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GCTAAACTCT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See CIAO1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CIAO1

    SOURCE GeneReport for Unigene cluster: Hs.12109
        SABiosciences Custom PCR Arrays for CIAO1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CIAO1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CIAO1 gene from 8/33 species (see all 33)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves CIAO11 cytosolic iron-sulfur protein assembly 1 77.4(n)
    85.62(a)
      426332  XM_423992.3  XP_423992.3 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia AL959987.22   -- 79.06(n)    AL959987.2 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc559112 similar to WD40 protein Ciao1 77.11(n)   393116  BC044534.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG127973
    Ciao11
    CG12797-PA1 60(a)3
    61.69(n)1
    60.95(a)1
      51C53
    366551  NM_137152.31  NP_610996.11 
    worm
    (Caenorhabditis elegans)
    Secernentea Y18D10A.93
    CELE_Y18D10A.91
    WD domain, G-beta repeat3
    Protein Y18D10A.91
    37(a)3
    49.89(n)1
    42.86(a)1
      I(12861246-12866314)3
    1731521  NM_060846.31  NP_493247.21 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes CIA11 Cia1p 50.52(n)
    46.74(a)
      851860   NP_010553.3 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons emb13451 transducin/WD-40 repeat-containing protein 54.93(n)
    52.02(a)
      817147  NM_128165.3  NP_565615.1 
    rice
    (Oryza sativa)
    Liliopsida Os07g02520001 hypothetical protein 56.11(n)
    52.04(a)
      4342847  NM_001065837.1  NP_001059302.1 


    ENSEMBL Gene Tree for CIAO1 (if available)
    TreeFam Gene Tree for CIAO1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CIAO1 gene
    WSB22  WSB12  

    CIAO1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/147 NCBI SNPs in CIAO1 are shown (see all 147    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs729376581,2
    C,--90892147(+) AATAGC/GAGCAG 2 -- int12Minor allele frequency- G:0.02WA 120
    rs729376601,2
    --90893087(+) CACGCC/TGCCCA 2 -- int10--------
    rs23017071,2
    C,F,A,H,--90893343(-) CTCGAA/GCTACC 2 -- us2k118Minor allele frequency- G:0.21EA MN NS NA 4684
    rs1479905301,2
    --96929925(+) ACAGCA/GGGGAA 3 -- us2k1 int10--------
    rs1416388071,2
    --96930010(+) TCTGAA/TAGGCG 3 -- int1 us2k10--------
    rs1505025511,2
    --96930015(+) TAGGCA/GGTGCA 3 -- us2k1 int10--------
    rs1398686681,2
    --96930116(+) TTGGGA/GTTGAT 3 -- int1 us2k10--------
    rs1170302551,2
    --96930406(+) TCTTCC/TGATTA 3 -- int1 us2k11Minor allele frequency- T:0.01EA 120
    rs1173193101,2
    F,--96930504(+) AAAGTT/CCCTTT 3 -- us2k1 int11Minor allele frequency- C:0.04EA 120
    rs1125899651,2
    --96930559(+) ACAGGA/CTCCTT 3 -- int1 us2k12Minor allele frequency- C:0.05CSA EA 122

    HapMap Linkage Disequilibrium report for CIAO1 (96931870 - 96939917 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for CIAO1
         1 CNV: 4300
    Human Gene Mutation Database (HGMD): CIAO1

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    CIAO1 for disorders           About GeneDecksing

    OMIM gene information: 604333    OMIM disorders: --

    1 disease for CIAO1:    About MalaCards
    wilms tumor


    Export disorders for CIAO1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CIAO1 gene, integrated from 9 sources (see all 26):
    (articles sorted by number of sources associating them with CIAO1)
        Utopia: connect your pdf to the dynamic
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    1. Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PubMed id 10493829)1, 2, 3 Loftus B.J.... Adams M.D. (1999)
    2. Ciao 1 is a novel WD40 protein that interacts with the tumor suppressor protein WT1. (PubMed id 9556563)1, 2, 3 Johnstone R.W.... Shi Y. (1998)
    3. Structure of the yeast WD40 domain protein Cia1, a component acting late in iron-sulfur protein biogenesis. (PubMed id 17937914)1, 2 Srinivasan V.... Lill R. (2007)
    4. CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation. (PubMed id 17041588)1, 2 Higa L.A.... Zhang H. (2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    7. MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. (PubMed id 22678362)2 Stehling O....Lill R. (2012)
    8. MMS19 links cytoplasmic iron-sulfur cluster assembly t o DNA metabolism. (PubMed id 22678361)2 Gari K....Boulton S.J. (2012)
    9. Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
    10. The mammalian DUF59 protein Fam96a forms two distinct types of domain-swapped dimer. (PubMed id 22683786)2 Chen K.E.... Martin J.L. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9391 HGNC: 14280 AceView: CIAO1 Ensembl:ENSG00000144021 euGenes: HUgn9391
    ECgene: CIAO1 H-InvDB: CIAO1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CIAO1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CIAO1 gene:
    Search GeneIP for patents involving CIAO1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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