CHTF8 Gene
protein-coding GIFtS: 43
GCID: GC16M069151
|
|
CTF8, chromosome transmission fidelity factor 8 homolog...
| |
Aliases
for CHTF8 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| CTF8, Chromosome Transmission Fidelity Factor 8 Homolog (S. Cerevisiae)1 2 | | FLJ204001 | | CTF81 2 3 | | Chromosome Transmission Fidelity Protein 8 Homolog2 | | DERPC1 2 3 | | HCTF81 | | Decreased Expression In Renal And Prostate Cancer Protein2 3 | | |
| External Ids: | HGNC: 243531 | Entrez Gene: 549212 | Ensembl: ENSG000001688027 | OMIM: 6132025 | UniProtKB: P0CG123 |
|---|
| UniProtKB: P0CG133 | | ORGUL members: | |
|---|
| NONCODE:n409100 | |
Export aliases for CHTF8 gene to outside databasesPrevious GC identifers: GC16M067714 GC16M055024
Summaries
for CHTF8 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CHTF8:
This gene encodes a short protein that forms part of the Ctf18 replication factor C (RFC) complex that occurs in bothyeast and mammals. The heteroheptameric RFC complex plays a role in sister chromatid cohesion and may load thereplication clamp PCNA (proliferating cell nuclear antigen) onto DNA during DNA replication and repair. This gene isubiquitously expressed and has been shown to have reduced expression in renal and prostate tumors. Alternativelyspliced transcript variants have been described. This gene has a pseudogene on chromosome X. (provided by RefSeq, Jan2010)
UniProtKB/Swiss-Prot: CTF8_HUMAN, P0CG13Function: Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission.Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consistsof CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs andhas weak ATPase activity that is stimulated the presence of primed DNA, replication protein A (RPA) and proliferatingcell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gappedDNA. It also interacts with and stimulates POLH, which is suggestive of a protein network that coordinates DNA repair,recombination and chromosome cohesion reactions with replication fork progression
Gene Wiki entry for CHTF8 (CTF8)
|
Genomic Views
for CHTF8 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010498.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CHTF8 gene promoter:
AREB6 HEN1 HNF-1 Pax-4a HNF-1A
Other transcription factors
Search SABiosciences Chromatin IP Primers for CHTF8
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHTF8 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q22.1 Ensembl cytogenetic band: 16q22.1 HGNC cytogenetic band: 16q22.1CHTF8 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M069151: view genomic region
(about GC identifiers)
Start:
|
69,151,912 bp from pter |
End:
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69,166,493 bp from pter |
Size:
|
14,582 bases |
Orientation:
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minus strand |
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Proteins
for CHTF8 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CTF8A_HUMAN, P0CG12 (See
protein sequence)Recommended Name: Chromosome transmission fidelity protein 8 homolog isoform 2 Size: 524 amino acids; 51391 Da
Subcellular location: Nucleus
Miscellaneous: Found in a common chromosomal region of deletion in breast cancer
Caution: mRNA expression studied by PubMed:12477976 does not differentiate between isoform 1 and isoform 2
Sequence caution: Sequence=CAD38758.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A8MYX8 Q71E72 Q8NDH8 Q8WV66 Q9NX73Alternative splicing: 2 isoforms: P0CG12-1 P0CG13-1 UniProtKB/Swiss-Prot: CTF8_HUMAN, P0CG13 (See
protein sequence) Recommended Name: Chromosome transmission fidelity protein 8 homolog Size: 121 amino acids; 13314 Da
Subunit: Component of the CTF18-RFC complex, which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. TheCTF18-RFC complex does not interact with the Rad9/Rad1/Hus1 complex. The CTF18-RFC complex interacts with POLH.CTF18/CTF8/DCC1 associate with PCNA. CTF8 exists as a dimer with DCC1
Subcellular location: Nucleus. Note=Associates with chromatin during S phase
Caution: mRNA expression studied by PubMed:12477976 does not differentiate between isoform 1 and isoform 2
Sequence caution: Sequence=AAQ08897.1; Type=Erroneous translation; Note=Wrong choice of CDS; Sequence=BAA91144.1;Type=Erroneous translation; Note=Wrong choice of CDS; Sequence=EAW83250.1; Type=Erroneous translation; Note=Wrongchoice of CDS;
Secondary accessions: A8MYX8 Q71E72 Q8NDH8 Q8WV66 Q9NX73Alternative splicing: 2 isoforms: P0CG13-1 P0CG12-1 Explore the universe of human proteins at neXtProt for CHTF8: NX_P0CG13
Post-translational modifications:
View modification sites using PhosphoSitePlus2 (DERPC)View neXtProt modification sites for NX_P0CG13
CHTF8 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001034779.1 NP_001035236.1
ENSEMBL proteins: ENSP00000408367 ENSP00000430899 ENSP00000430079 ENSP00000462519 ENSP00000381290 ENSP00000427718 ENSP00000455402 ENSP00000428130 ENSP00000427728 ENSP00000455699 ENSP00000305687
Human Recombinant Protein Products for CHTF8:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
CHTF8 for ontologies About GeneDecksing
CHTF8 Antibody Products:
Assay Products for CHTF8: |
Protein
Domains /
Families
for CHTF8 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CHTF8 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry P0CG12Graphical View of Domain Structure for InterPro Entry P0CG13ProtoNet protein and cluster: P0CG12 UniProtKB/Swiss-Prot: CTF8A_HUMAN, P0CG12Similarity: Belongs to the DERPC familyUniProtKB/Swiss-Prot: CTF8_HUMAN, P0CG13Similarity: Belongs to the CTF8 family |
Function
for CHTF8 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: CTF8A_HUMAN, P0CG12Function: Potential tumor suppressor. Inhibits prostate tumor cell growth, when overexpressed UniProtKB/Swiss-Prot: CTF8_HUMAN, P0CG13Function: Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission.Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consistsof CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs andhas weak ATPase activity that is stimulated the presence of primed DNA, replication protein A (RPA) and proliferatingcell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gappedDNA. It also interacts with and stimulates POLH, which is suggestive of a protein network that coordinates DNA repair,recombination and chromosome cohesion reactions with replication fork progression Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003677 | DNA binding |
IEA | -- |
CHTF8 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHTF8 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHTF8 (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): CHTF8 (NM_001040146) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CHTF8 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHTF8 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHTF8 |
|
Pathways & Interactions
for CHTF8 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CHTF8
STRING Interaction
Network Preview (showing 5 interactants - click image to see 9)
5/10 Interacting proteins for CHTF8 (P0CG133 ENSP000003812904) via UniProtKB, MINT, STRING, and/or I2D (see all 10)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
CHTF8 for ontologies About GeneDecksing
|
Drugs & Compounds
for CHTF8 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CHTF8
Search CenterWatch for drugs/clinical trials and news about CHTF8 / CTF8
|
Transcripts
for CHTF8 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CHTF8 gene (6 alternative transcripts): NM_001039690.3 NM_001040146.3 NM_001002847.1 NM_001040144.1 NM_001040145.1 NM_017804.3 Unigene Cluster for CHTF8: CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae) Hs.85962 [show with all ESTs]Unigene Representative Sequence: AF52516411 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000448552 ENST00000523421 ENST00000518041 ENST00000519534 ENST00000398235
ENST00000519520 ENST00000567763 ENST00000522497 ENST00000520529 ENST00000522091
ENST00000306585(uc002ewn.2 uc002ewp.2 uc002ewo.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHTF8 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHTF8 (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): CHTF8 (NM_001040146) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CHTF8 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHTF8 |
Additional cDNA sequence: AF525164.1 AK000407.1 AL833902.1 BC018700.2 BC069059.1 NR_033227.1 22 DOTS entries: DT.95195379 DT.80100606 DT.100822682 DT.100839004 DT.100822686 DT.100822689 DT.100773720 DT.120681234 DT.101983767 DT.95366397 DT.95366401 DT.100822684 DT.100838774 DT.120681042 DT.100822680 DT.100822681 DT.100822683 DT.102831935 DT.120681190 DT.75125276 DT.92039675 DT.95366396
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for CHTF8 (see all 7) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | · | 5d | · | 5e | · | 5f |
|---|
|
| SP1: | | | - | | - | | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | - | | | | | | | | | | | | | | |
| SP3: | | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | - | | - | | | | - | | - | | | | | | | | | | | | | | |
| SP5: | | | - | | - | | - | | | | - | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CHTF8
|
Expression
for CHTF8 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CHTF8 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTTCCGTAGC
About this image
See CHTF8 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CHTF8
SOURCE GeneReport for Unigene cluster: Hs.85962
UniProtKB/Swiss-Prot: CTF8A_HUMAN, P0CG12Tissue specificity: Ubiquitously expressed, with abundant expression in kidney, skeletal muscle, testis, liver, ovary,and heart and moderate expression in prostate. Expression is significantly reduced in renal and prostate tumors. Nodifferential expression in breast cancer cells, between lobular carcinoma and normal lobules
UniProtKB/Swiss-Prot: CTF8_HUMAN, P0CG13Tissue specificity: Ubiquitously expressed, with abundant expression in kidney, skeletal muscle, testis, liver, ovary,and heart and moderate expression in prostate. Expression is significantly reduced in renal and prostate tumors. Nodifferential expression in breast cancer cells, between lobular carcinoma and normal lobules
SABiosciences Custom PCR Arrays for CHTF8
Primer
Products: | | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CHTF8 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHTF8 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHTF8 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHTF8 |
Orthologs
for CHTF8 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CHTF8 gene from 9/21 species (see all 21) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Chtf81 , 5 |
CTF8, chromosome transmission fidelity factor 8 homolog more5
CTF8, chromosome transmission fidelity factor 81 |
94.77(n)1
91.74(a)1 |
|
8 (53.30 cM)5
2149871 NM_145412.31 NP_663387.31
1068838635 |
chicken
(Gallus gallus) |
Aves |
CHTF81 |
CTF8, chromosome transmission fidelity factor 8 homolog more |
69.35(n)
74.11(a) |
|
769609 XM_003641948.1 XP_003641996.1 |
lizard
(Anolis carolinensis) |
Reptilia |
CHTF86 |
-- |
68(a) |
1 ↔ 1 |
GL343914.1(9921-11890) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.105692 |
Xenopus laevis transcribed sequence with weak similarity more |
75.34(n) |
|
BI443665.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.242402 |
Transcribed sequence with weak similarity to protein more |
75.25(n) |
|
BM861379.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG340011 |
CG34001 |
50.71(n)
44.44(a) |
|
3885640 NM_001038910.2 NP_001033999.2 |
worm
(Caenorhabditis elegans) |
Secernentea |
T22C1.46 |
Protein T22C1.4 |
27(a) |
1 ↔ 1 |
I(7940127-7940752) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT5G522206 |
chromosome transmission fidelity protein 8 |
25(a) |
1 ↔ 1 |
5(21207097-21207716) |
rice
(Oryza sativa) |
Liliopsida |
-- |
expressed protein |
25(a) |
1 ↔ 1 |
9(7333171-7334241) |
ENSEMBL Gene Tree for CHTF8 (if available)
TreeFam Gene Tree for CHTF8 (if available) |
Paralogs
for CHTF8 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CHTF8 gene
CHTF8 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for CHTF8
PGOHUM00000241728 PGOHUM00000241729
|
Genomic Variants
for CHTF8 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CHTF8 (69151912 - 69166493 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CHTF8: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHTF8 |
|
Disorders
/ Diseases
for CHTF8 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CHTF8 for disorders About GeneDecksing
OMIM gene information: 613202
OMIM disorders: --
6  diseases for CHTF8: About MalaCardsprostatitis prostate cancer intrahepatic cholangiocarcinoma cholangiocarcinoma
breast cancer carcinoma
Export disorders for CHTF8 gene to outside databases
|
Publications
for CHTF8 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CHTF8 gene, integrated from 9 sources (see all 19):
(articles sorted by number of sources associating them with CHTF8) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning and characterization of hCTF18, hCTF8, and hDCC1. Human homologs of a Saccharomyces cerevisiae complex involved in sister chromatid cohesion establishment. (PubMed id 12766176)1, 2, 3 Merkle C.J.... Chen J. (2003)
- A second proliferating cell nuclear antigen loader complex, Ctf18- replication factor C, stimulates DNA polymerase eta activity. (PubMed id 17545166)1, 2 Shiomi Y.... Tsurimoto T. (2007)
- The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)1, 2 Martin J.... Pennacchio L.A. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA. (PubMed id 12930902)1, 2 Bermudez V.P....Hurwitz J. (2003)
- A human novel gene DERPC on 16q22.1 inhibits prostate tumor cell growth and its expression is decreased in prostate and renal tumors. (PubMed id 12477976)1, 2 Sun M....Zou Z. (2002)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Stable interaction between the human proliferating ce ll nuclear antigen loader complex Ctf18-replication factor C (RFC) and DNA poly merase {epsilon} is mediated by the cohesion-specific subunits, Ctf18, Dcc1, an d Ctf8. (PubMed id 20826785)1 Murakami T....Tsurimoto T. (2010)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
|
External Searches for CHTF8 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CHTF8 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CHTF8 gene
(According to HUGE)
About This Section
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Specialized Databases showing CHTF8 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for CHTF8 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for CHTF8 gene:
Search GeneIP for patents involving CHTF8
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for CHTF8 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CHTF8 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CHTF8 | | Browse OriGene genome-wide validated SYBR primer pairs | | | OriGene Protein Over-expression Lysate for CHTF8 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CHTF8 | | OriGene 3'-UTR Clone for CHTF8 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHTF8 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHTF8 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for CHTF8 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CHTF8 | | OriGene Custom Protein Services for CHTF8 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CHTF8 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHTF8 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHTF8 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CHTF8 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHTF8 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHTF8 |
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| | | | Search Tocris compounds for CHTF8 |
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 | | | CHTF8 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHTF8 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for CHTF8 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHTF8 |
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