CHTF18 Gene
protein-coding GIFtS: 48
GCID: GC16P000838
|
|
CTF18, chromosome transmission fidelity factor 18 homolog...(Previous name: chromosome 16 open reading frame 41 )
(Previous symbol: C16orf41)
| |
Aliases
for CHTF18 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| CTF18, Chromosome Transmission Fidelity Factor 18 Homolog (S.Cerevisiae)1 2 | | C321D2.32 | | CHL121 2 3 5 | | RUVBL2 | | C16orf411 2 3 | | C321D2.3 (Novel Protein)2 | | C321D2.41 2 | | C321D2.4 (Novel Protein)2 | | Ctf181 2 | | Chromosome Transmission Fidelity Protein 18 Homolog2 | | HCTF181 | | Homolog Of Yeast CHL122 | | CTF183 5 | | Some Homology With Holliday Junction DNA Helicase RUVB Like2 | | Chromosome 16 Open Reading Frame 411 | | EC 3.6.18 | | C321D2.22 | | |
Export aliases for CHTF18 gene to outside databasesPrevious GC identifers: GC16P000859 GC16P000778 GC16P000762 |
Summaries
for CHTF18 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CHTF18:
CHTF18, CHTF8 (MIM 613202), and DCC1 (DSCC1; MIM 613203) are components of an alternative replication factor C (RFC)(see MIM 600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003(PubMed 12766176); Bermudez et al., 2003 (PubMed 12930902)).(supplied by OMIM, Dec 2009)
UniProtKB/Swiss-Prot: CTF18_HUMAN, Q8WVB6Function: Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission.Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consistsof CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs andhas weak ATPase activity that is stimulated by the presence of primed DNA, replication protein A (RPA) and byproliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA ontoprimed and gapped DNA. It also interacts with and stimulates DNA polymerase POLH
Gene Wiki entry for CHTF18
|
Genomic Views
for CHTF18 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010393.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CHTF18 gene promoter:
Elk-1 Spz1 p53 Nkx2-5 E47 POU2F1a HOXA5 NF-Y CBF(2)
Other transcription factors
Search SABiosciences Chromatin IP Primers for CHTF18
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHTF18 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3CHTF18 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P000838: view genomic region
(about GC identifiers)
Start:
|
838,046 bp from pter |
End:
|
850,737 bp from pter |
Size:
|
12,692 bases |
Orientation:
|
plus strand |
|
Proteins
for CHTF18 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CTF18_HUMAN, Q8WVB6 (See
protein sequence)Recommended Name: Chromosome transmission fidelity protein 18 homolog Size: 975 amino acids; 107383 Da
Subunit: Component of the CTF18-RFC complex, which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. Duringassembly of the CTF18-RFC complex, CTF18 may first assemble into a subcomplex with RFC2, RFC3, RFC4 and RFC5. CTF18then interacts directly with CTF8, which in turn interacts with DCC1. The CTF18-RFC complex associates with PCNA andwith DNA polymerase POLH. The CTF18-RFC complex does not interact with the Rad9/Rad1/Hus1 complex. CTF18 interactswith SMC1A and RAD21
Subcellular location: Nucleus. Note=Associates with chromatin during S phase
Sequence caution: Sequence=AAH06437.1; Type=Erroneous initiation; Sequence=BAB15766.1; Type=Erroneous initiation;
Secondary accessions: B7ZBA2 D3DU68 Q7Z6Y4 Q7Z6Y6 Q9BR83 Q9BRG5 Q9H7K3Alternative splicing: 3 isoforms: Q8WVB6-1 Q8WVB6-2 Q8WVB6-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for CHTF18: NX_Q8WVB6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8WVB6
2 DME Specific Peptides for CHTF18 (Q8WVB6)
CHTF18 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_071375.1
ENSEMBL proteins: ENSP00000262315 ENSP00000456998 ENSP00000406252 ENSP00000399111 ENSP00000412015 ENSP00000454679 ENSP00000313029
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
CHTF18 for ontologies About GeneDecksing
CHTF18 Antibody Products:
Assay Products for CHTF18: |
Protein
Domains /
Families
for CHTF18 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CHTF18 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8WVB6ProtoNet protein and cluster: Q8WVB6 UniProtKB/Swiss-Prot: CTF18_HUMAN, Q8WVB6Similarity: Belongs to the activator 1 small subunits family. CTF18 subfamily |
Function
for CHTF18 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CTF18_HUMAN, Q8WVB6Function: Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission.Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consistsof CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs andhas weak ATPase activity that is stimulated by the presence of primed DNA, replication protein A (RPA) and byproliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA ontoprimed and gapped DNA. It also interacts with and stimulates DNA polymerase POLHEnzyme Number (IUBMB): EC 3.6.12
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHTF18 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHTF18
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CHTF18 (NM_022092) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CHTF18 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHTF18 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHTF18 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
CHTF18 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Chtf18tm1KhK for CHTF18
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Chtf18):
CHTF18 for phenotypes About GeneDecksing
|
Pathways & Interactions
for CHTF18 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CHTF18
STRING Interaction
Network Preview (showing 5 interactants - click image to see 16)
5/17 Interacting proteins for CHTF18 (Q8WVB63 ENSP000002623154) via UniProtKB, MINT, STRING, and/or I2D (see all 17)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
CHTF18 for ontologies About GeneDecksing
|
Drugs & Compounds
for CHTF18 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CHTF18
Search CenterWatch for drugs/clinical trials and news about CHTF18 / CTF18
|
Transcripts
for CHTF18 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CHTF18 gene: NM_022092.2 Unigene Cluster for CHTF18: CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) Hs.153850 [show with all ESTs]Unigene Representative Sequence: AK02447618/19 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19): ENST00000464728(uc002ckg.4) ENST00000262315(uc010bre.1 uc002cke.4)
ENST00000570058 ENST00000563545 ENST00000479976 ENST00000455171(uc002ckf.4)
ENST00000440239 ENST00000471202(uc010uus.1 uc010brf.3) ENST00000491530
ENST00000426047 ENST00000484349 ENST00000569270 ENST00000567620 ENST00000565787
ENST00000461268 ENST00000493715 ENST00000498439 ENST00000564940
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHTF18 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHTF18
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CHTF18 (NM_022092) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CHTF18 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHTF18 |
Additional cDNA sequence: AK024476.1 AK128869.1 AK293846.1 AK309804.1 BC006278.2 BC006437.1 BC018184.1 9 DOTS entries: DT.97840026 DT.423009 DT.100751771 DT.101975373 DT.97841074 DT.102828212 DT.92424897 DT.95375344 DT.120727801 24/106 AceView cDNA sequences (see all 106): AK128869 AW631061 BM701214 BC006437 AI916173 AI341250 AA352175 BQ962210 BU633872 AI620989 CA421425 AW236312 BQ645686 AA558991 BQ231004 BM806765 BM127632 BU509771 CK906217 BF513105 BE898071 AK024476 BM674122 BE795677
GeneLoc Exon Structure
5/18 Alternative Splicing Database (ASD) splice patterns (SP) for CHTF18 (see all 18) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | · | 3c | · | 3d | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | · | 9c | ^ | 10 | ^ | 11a | · | 11b | ^ | 12a | · | 12b | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 12c | ^ | 13a | · | 13b | ^ | 14a | · | 14b | ^ | 15a | · | 15b | ^ | 16a | · | 16b | ^ | 17 | ^ | 18 | ^ | 19a | · | 19b | ^ | 20 | ^ | 21a | · | 21b | · | 21c | ^ | 22a | · | 22b | ^ | 23 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CHTF18
|
Expression
for CHTF18 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CHTF18 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCCTCGCATT
About this image
See CHTF18 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CHTF18
SOURCE GeneReport for Unigene cluster: Hs.153850
SABiosciences Custom PCR Arrays for CHTF18
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHTF18
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CHTF18 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHTF18 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHTF18 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHTF18 |
Orthologs
for CHTF18 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CHTF18 gene from 9/34 species (see all 34) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
CHTF181 |
CTF18, chromosome transmission fidelity factor 18 homolog more |
66.2(n)
57.62(a) |
|
416531 XM_414833.3 XP_414833.3 |
lizard
(Anolis carolinensis) |
Reptilia |
CHTF186 |
-- |
53(a) |
1 ↔ 1 |
GL343650.1(353661-385914) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.153772 |
Xenopus laevis transcribed sequence with weak similarity more |
74.95(n) |
|
48014175 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.209032 |
Transcribed sequence with weak similarity to protein more |
71.62(n) |
|
CB360273.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
cutlet1 |
CG33122-PA |
49.11(n)
38.38(a) |
|
44637 NM_175955.2 NP_787969.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
K08F4.16 |
-- |
21(a) |
1 ↔ 1 |
IV(10122098-10126653) |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
CTF18(YMR078C)4
CTF181 |
Subunit of a complex with Ctf8p that shares some subunits more4
Ctf18p1 |
38.49(n)1
29.61(a)1 |
|
13(424728-422503)4
8551021, 4 NP_013795.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
CTF181 |
chromosome transmission fidelity protein 18 |
42.33(n)
34.6(a) |
|
839431 NM_100352.2 NP_171966.2 |
rice
(Oryza sativa) |
Liliopsida |
Os03g02648001 |
hypothetical protein |
42.96(n)
33.5(a) |
|
4332344 NM_001056179.2 NP_001049644.2 |
ENSEMBL Gene Tree for CHTF18 (if available)
TreeFam Gene Tree for CHTF18 (if available) |
Paralogs
for CHTF18 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for CHTF18 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CHTF18 (838046 - 850737 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 7 variations for CHTF18
7 CNVs: 10493 29986 3987 49763 5329 30732 29983 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHTF18 |
|
Disorders
/ Diseases
for CHTF18 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CHTF18 for disorders About GeneDecksing
OMIM gene information: 613201
OMIM disorders: --
1  disease for CHTF18: About MalaCardsmalaria
Export disorders for CHTF18 gene to outside databases
|
Publications
for CHTF18 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CHTF18 gene, integrated from 9 sources (see all 33):
(articles sorted by number of sources associating them with CHTF18) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A second proliferating cell nuclear antigen loader complex, Ctf18- replication factor C, stimulates DNA polymerase eta activity. (PubMed id 17545166)1, 2 Shiomi Y.... Tsurimoto T. (2007)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA. (PubMed id 12930902)1, 2 Bermudez V.P....Hurwitz J. (2003)
- Cloning and characterization of hCTF18, hCTF8, and hDCC1. Human homologs of a Saccharomyces cerevisiae complex involved in sister chromatid cohesion establishment. (PubMed id 12766176)1, 2 Merkle C.J.... Chen J. (2003)
- A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein. (PubMed id 12171929)1, 3 Ohta S....Tsurimoto T. (2002)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
|
External Searches for CHTF18 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CHTF18 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CHTF18 gene
(According to HUGE)
About This Section
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Specialized Databases showing CHTF18 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for CHTF18 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for CHTF18 gene:
Search GeneIP for patents involving CHTF18
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for CHTF18 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CHTF18 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CHTF18 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHTF18 | | | OriGene Protein Over-expression Lysate for CHTF18 | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for CHTF18 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHTF18 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHTF18 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CHTF18 | | OriGene Custom Protein Services for CHTF18 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CHTF18 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHTF18 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHTF18 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CHTF18 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHTF18 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHTF18 |
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| | | | Search Tocris compounds for CHTF18 |
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 | | | CHTF18 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHTF18 |
|  |  |  | | | | Search ThermoFisher Antibodies for CHTF18 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHTF18 |
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