CHST11 Gene
protein-coding GIFtS: 55
GCID: GC12P104783
|
|
carbohydrate (chondroitin 4) sulfotransferase 11
| |
Aliases
for CHST11 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Carbohydrate (Chondroitin 4) Sulfotransferase 111 2 | | C4ST-12 3 | | C4ST11 2 3 | | EC 2.8.2.53 8 | | C4ST1 2 | | C4St-11 | | HSA2695371 2 | | Carbohydrate Sulfotransferase 112 | | Chondroitin 4-O-Sulfotransferase 12 3 | | IgH/CHST11 Fusion2 | | C4S-12 3 | | Chondroitin 4-Sulfotransferase 13 |
Export aliases for CHST11 gene to outside databasesPrevious GC identifers: GC12P103353 GC12P103351 GC12P101909 |
Summaries
for CHST11 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CHST11:
The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, andcatalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin.Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfacesof many cells and extracellular matrices. A chromosomal translocation involving this gene and IgH, t(12;14)(q23;q32),has been reported in a patient with B-cell chronic lymphocytic leukemia. Alternatively spliced transcript variantsencoding different isoforms have been found for this gene. (provided by RefSeq, Aug 2011)
UniProtKB/Swiss-Prot: CHSTB_HUMAN, Q9NPF2Function: Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin.Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfacesof many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentiallysulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6-di-O-sulfated GalNAc when chondroitinsulfate C is used as an acceptor
Gene Wiki entry for CHST11
|
Genomic Views
for CHST11 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_029419.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CHST11 gene promoter:
NF-1 AML1a MyoD XBP-1 Nkx2-5 YY1 GATA-1 C/EBPalpha PPAR-gamma1 PPAR-gamma2
Other transcription factors
Search SABiosciences Chromatin IP Primers for CHST11
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHST11 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q Ensembl cytogenetic band: 12q23.3 HGNC cytogenetic band: 12q23.3CHST11 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12P104783: view genomic region
(about GC identifiers)
Start:
|
104,849,073 bp from pter |
End:
|
105,155,792 bp from pter |
Size:
|
306,720 bases |
Orientation:
|
plus strand |
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Proteins
for CHST11 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CHSTB_HUMAN, Q9NPF2 (See
protein sequence)Recommended Name: Carbohydrate sulfotransferase 11 Size: 352 amino acids; 41555 Da
Subcellular location: Golgi apparatus membrane; Single-pass type II membrane protein (By similarity)
Secondary accessions: A8K4F8 Q9NXY6 Q9NY36Alternative splicing: 2 isoforms: Q9NPF2-1 Q9NPF2-2 Explore the universe of human proteins at neXtProt for CHST11: NX_Q9NPF2
Post-translational modifications:
N-glycosylated; required for activity and stability1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NPF2
4/7 DME Specific Peptides for CHST11 (Q9NPF2) (see all 7)
CHST11 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001167453.1 NP_060883.1
ENSEMBL proteins: ENSP00000449093 ENSP00000450004 ENSP00000305725 ENSP00000448678 ENSP00000449095 Reactome Protein details: Q9NPF2
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
CHST11 for ontologies About GeneDecksing
CHST11 Antibody Products:
Assay Products for CHST11: |
Protein
Domains /
Families
for CHST11 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CHST11 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9NPF2ProtoNet protein and cluster: Q9NPF2 UniProtKB/Swiss-Prot: CHSTB_HUMAN, Q9NPF2Similarity: Belongs to the sulfotransferase 2 family |
Function
for CHST11 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CHSTB_HUMAN, Q9NPF2Function: Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin.Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfacesof many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentiallysulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6-di-O-sulfated GalNAc when chondroitinsulfate C is used as an acceptorCatalytic activity: 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 4'-sulfateBiophysicochemical properties: Kinetic parameters: KM=0.5 uM for PAPS; KM=2.1 mM for chondroitin;Enzyme Number (IUBMB): EC 2.8.2.51 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHST11 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHST11 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): CHST11 (NM_018413) | |  | Sino Biological Human cDNA Clone for CHST11 | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CHST11 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHST11 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHST11 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0001537 | N-acetylgalactosamine 4-O-sulfotransferase activity |
IDA | 11056388 | | GO:0008146 | sulfotransferase activity |
-- | -- | | GO:0047756 | chondroitin 4-sulfotransferase activity |
IDA | 11056388 | | GO:0050659 | N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity |
IEA | -- |
CHST11 for ontologies About GeneDecksing
Animal Models:
6 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Chst11):
CHST11 for phenotypes About GeneDecksing
|
Pathways & Interactions
for CHST11 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | MPS IIIC - Sanfilippo syndrome C | | | 2 | dermatan sulfate biosynthesis | | | 3 | Disease | | | 4 | Metabolism | | | 5 | Endochondral Ossification | |
Pathway sources
See GeneCards unified pathways
Show all pathways
4  BioSystems Pathways for CHST11
5/18 
Reactome Pathways for CHST11 (see all 18)
2 
Kegg Pathways (Kegg details for CHST11):
CHST11 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CHST11
STRING Interaction
Network Preview (showing 5 interactants - click image to see 18)
5/18 Interacting proteins for CHST11 (ENSP000003057254) via UniProtKB, MINT, STRING, and/or I2D (see all 18)About this table
Gene Ontology (GO): 5/21 biological process terms (GO ID links to tree view) (see all 21): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0002063 | chondrocyte development |
IEA | -- | | GO:0005975 | carbohydrate metabolic process |
TAS | -- | | GO:0007585 | respiratory gaseous exchange |
IEA | -- | | GO:0009791 | post-embryonic development |
IEA | -- | | GO:0016051 | carbohydrate biosynthetic process |
IEA | -- |
CHST11 for ontologies About GeneDecksing
|
Drugs & Compounds
for CHST11 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
CHST11 for compounds About GeneDecksing
 Browse Tocris compounds for CHST11
5 HMDB Compounds for CHST11 About this table
7 Novoseek chemical compound relationships for CHST11 gene About this table
Search CenterWatch for drugs/clinical trials and news about CHST11 / CHSTB
|
Transcripts
for CHST11 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CHST11 gene (2 alternative transcripts): NM_001173982.1 NM_018413.5 Unigene Cluster for CHST11: Carbohydrate (chondroitin 4) sulfotransferase 11 Hs.17569 [show with all ESTs]Unigene Representative Sequence: NM_0184136 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000550711 ENST00000547956 ENST00000549260(uc001tky.3) ENST00000303694(uc001tkz.3)
ENST00000546689 ENST00000549016
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHST11 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHST11 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): CHST11 (NM_018413) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CHST11 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHST11 |
Additional cDNA sequence: AB042326.1 AF131762.1 AF239820.1 AJ269537.2 AJ289134.1 AK123676.1 AK290923.1 AK313217.1 AL833176.1 AY533204.1 AY533205.1 BC013315.1 BC030271.1 BC061524.1 5 DOTS entries: DT.97765459 DT.100784578 DT.100784575 DT.121137744 DT.91649628 24/154 AceView cDNA sequences (see all 154): BU174298 H97252 BQ009789 AJ289134 AA634815 BC061524 CD364688 BU632779 AW961343 CD676264 AA465726 CA309228 CB529524 CR608680 AW593088 CA432716 BM763953 AW028754 R69560 AA318376 AA553685 BU838915 CD673275 CD367266
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for CHST11 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3 |
|---|
|
| SP1: | | | | | - | | | | - | | | | |
| SP2: | | | | | | | | | - | | | | |
| SP3: | | | | | - | | | | | | | | |
| SP4: | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CHST11
|
Expression
for CHST11 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CHST11 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See CHST11 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CHST11
SOURCE GeneReport for Unigene cluster: Hs.17569
UniProtKB/Swiss-Prot: CHSTB_HUMAN, Q9NPF2Tissue specificity: Widely expressed. Highly expressed in spleen, thymus, bone marrow, peripheral blood leukocytes,lymph node, heart, brain, lung and placenta
SABiosciences Expression via Pathway-Focused PCR Array including CHST11:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHST11
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CHST11 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHST11 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHST11 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHST11 |
Orthologs
for CHST11 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CHST11 gene from 5/17 species (see all 17) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
CHST111 |
carbohydrate (chondroitin 4) sulfotransferase 11 |
84.93(n)
93.91(a) |
|
418081 XM_416316.3 XP_416316.3 |
lizard
(Anolis carolinensis) |
Reptilia |
CHST116 |
-- |
95(a) |
1 ↔ 1 |
5(18611229-18612086) |
African clawed frog
(Xenopus laevis) |
Amphibia |
chst11-prov2 |
carbohydrate sulfotransferase 11 |
72.65(n) |
|
BC056117.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
chst111 |
carbohydrate (chondroitin 4) sulfotransferase 11 |
75.31(n)
78.67(a) |
|
404232 NM_212824.2 NP_997989.2 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG317431 |
CG31743 |
51.02(n)
39.71(a) |
|
326156 NM_135976.2 NP_609820.1 |
ENSEMBL Gene Tree for CHST11 (if available)
TreeFam Gene Tree for CHST11 (if available) |
Paralogs
for CHST11 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CHST11 gene
- CHST122 CHST132 CHST92 CHST102 CHST82 CHST142
6 SIMAP similar genes for CHST11 using alignment to 4 protein entries: CHSTB_HUMAN (see all proteins):CHST13 CHST9 CHST8 CHST12 CHST10 CHST14
CHST11 for paralogs About GeneDecksing
|
Genomic Variants
for CHST11 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CHST11 (104849073 - 105099073 bp, first 250kb of CHST11)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for CHST11
1 CNV: 4786
3 Indels: 48935 71563 71562 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHST11 |
|
Disorders
/ Diseases
for CHST11 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CHST11 for disorders About GeneDecksing
OMIM gene information: 610128
OMIM disorders: --
UniProtKB/Swiss-Prot: CHSTB_HUMAN, Q9NPF2
Note=A chromosomal aberration involving CHST11 is found in B-cell chronic lymphocytic leukemias. Translocationt(12;14)(q23;q32) with IgH
9  diseases for CHST11: About MalaCardschronic lymphocytic leukemia lymphocytic leukemia leukemia cutaneous lupus erythematosus
costello syndrome lupus erythematosus prostate cancer prostatitis
malaria
1 disease from the University of Copenhagen DISEASES database for CHST11:Cutaneous lupus erythematosus Human Genome Epidemiology (HuGE) Navigator: CHST11 (5 documents)
Export disorders for CHST11 gene to outside databases
|
Publications
for CHST11 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CHST11 gene, integrated from 9 sources (see all 35):
(articles sorted by number of sources associating them with CHST11) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning and expression of two distinct human chondroitin 4- O-sulfotransferases that belong to the HNK-1 sulfotransferase gene family. (PubMed id 10781601)1, 2, 3 Hiraoka N.... Fukuda M. (2000)
- Molecular cloning, expression, and chromosomal mapping of human chondroitin 4-sulfotransferase, whose expression pattern in human tissues is different from that of chondroitin 6-sulfotransferase. (PubMed id 11056388)1, 2, 9 Okuda T.... Habuchi O. (2000)
- Deregulation of the carbohydrate (chondroitin 4) sulfotransferase 11 (CHST11) gene in a B-cell chronic lymphocytic leukemia with a t(12;14)(q23;q32). (PubMed id 15273723)1, 2, 9 Schmidt H.H.... Chaganti R.S.K. (2004)
- Specificities of three distinct human chondroitin/dermatan N- acetylgalactosamine 4-O-sulfotransferases demonstrated using partially desulfated dermatan sulfate as an acceptor. Implication of differential roles in dermatan sulfate biosynthesis. (PubMed id 12847091)1, 2, 9 Mikami T.... Sugahara K. (2003)
- N-linked oligosaccharides are required to produce and stabilize the active form of chondroitin 4-sulphotransferase-1. (PubMed id 15628971)1, 2 Yusa A.... Habuchi O. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Molecular cloning and expression of chondroitin 4-sulfotransferase. (PubMed id 10722746)1, 9 Yamauchi S....Habuchi O. (2000)
- Identification and characterization of TGFbeta-depend ent and -independent cis-regulatory modules in the C4ST-1/CHST11 locus. (PubMed id 19937589)1, 9 Willis C.M....KlA1ppel M. (2009)
- C4ST-1/CHST11-controlled chondroitin sulfation interfe res with oncogenic HRAS signaling in Costello syndrome. (PubMed id 22317973)1 Kluppel M....Hinek A. (2012)
|
External Searches for CHST11 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CHST11 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CHST11 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CHST11 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CHST11 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CHST11 gene:
Search GeneIP for patents involving CHST11
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CHST11 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CHST11 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CHST11 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHST11 | | | OriGene Protein Over-expression Lysate for CHST11 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CHST11 | | OriGene 3'-UTR Clone for CHST11 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHST11 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHST11 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CHST11 | | OriGene Custom Protein Services for CHST11 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CHST11 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHST11 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHST11 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CHST11 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHST11 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHST11 |
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| | | | Search Tocris compounds for CHST11 |
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 | | | CHST11 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHST11 |
|  |  |  | | | | Search ThermoFisher Antibodies for CHST11 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHST11 |
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