CHST10 Gene(Protein Coding)

Carbohydrate Sulfotransferase 10

GCID:: GC02M100466

GIFtS:: 57

Genes Participants

Aliases for CHST10 Gene

Carbohydrate Sulfotransferase 10 ² ³ ⁵
HNK-1 Sulfotransferase ³ ⁴
HuHNK-1ST ³ ⁴
HNK-1ST ³ ⁴
HNK1ST ³ ⁴
EC 2.8.2.- ⁴
EC 2.8.2 ⁶³

External Ids for CHST10 Gene

HGNC: 19650
Entrez Gene: 9486
Ensembl: ENSG00000115526
OMIM: 606376
UniProtKB: O43529

Previous GeneCards Identifiers for CHST10 Gene

GC02M099461
GC02M100612
GC02M100629
GC02M101008
GC02M094773

Export aliases for CHST10 gene to outside databases

Summaries for CHST10 Gene

Entrez Gene Summary for CHST10 Gene

This protein encoded by this gene transfers sulfate to the C-3 hydroxyl of terminal glucuronic acid of protein- and lipid-linked oligosaccharides. This protein was first identified as a sulfotransferase that acts on the human natural killer-1 (HNK-1) glycan; HNK-1 is a carbohydrate involved in neurodevelopment and synaptic plasticity.[provided by RefSeq, Feb 2011]

GeneCards Summary for CHST10 Gene

CHST10 (Carbohydrate Sulfotransferase 10) is a Protein Coding gene. Among its related pathways are Transport to the Golgi and subsequent modification and Articular Cartilage Extracellular Matrix Pathway. GO annotations related to this gene include sulfotransferase activity and HNK-1 sulfotransferase activity. An important paralog of this gene is CHST9.

UniProtKB/Swiss-Prot for CHST10 Gene

CHSTA_HUMAN,O43529

Catalyzes the transfer of sulfate to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides. Participates in biosynthesis of HNK-1 carbohydrate structure, a sulfated glucuronyl-lactosaminyl residue carried by many neural recognition molecules, which is involved in cell interactions during ontogenetic development and in synaptic plasticity in the adult. May be indirectly involved in synapse plasticity of the hippocampus, via its role in HNK-1 biosynthesis.

Gene Wiki entry for CHST10 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CHST10 Gene

Genomics for CHST10 Gene

Regulatory Elements for CHST10 Gene

Enhancers for CHST10 Gene

GeneHancer Identifier	Score	Enhancer Sources	TSS distance (kb)	Number of Genes Away	Size (kb)	Transcription Factor Binding Sites within enhancer	Other Gene Targets for Enhancer

Enhancers around CHST10 on UCSC Golden Path with GeneCards custom track

Promoters for CHST10 Gene

Ensembl Regulatory Elements (ENSRs)	TSS Distance (bp)	Size (bp)	Binding Sites for Transcription Factors within promoters

ENSRs around CHST10 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the CHST10 gene promoter:

See All at QIAGEN

Regulatory Element Products

Genomic Location for CHST10 Gene

Chromosome:: 2

Start:: 100,391,860 bp from pter
End:: 100,417,668 bp from pter

Size:: 25,809 bases
Orientation:: Minus strand

Genomic View for CHST10 Gene

Genes around CHST10 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:

2q11.2 by Ensembl
2q11.2 by Entrez Gene
2q11.2 by HGNC

CHST10 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)

Genomic Location for CHST10 Gene — Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for CHST10 Gene

Proteins for CHST10 Gene

Protein details for CHST10 Gene (UniProtKB/Swiss-Prot)
Protein Symbol:

O43529-CHSTA_HUMAN

Recommended name:

Carbohydrate sulfotransferase 10

Protein Accession:

O43529

Secondary Accessions:
- Q53T18
Protein attributes for CHST10 Gene

Size:

356 amino acids

Molecular mass:

42207 Da

Quaternary structure:

No Data Available

neXtProt entry for CHST10 Gene

Proteomics data for CHST10 Gene at MOPED

Protein Expression for CHST10 Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Selected DME Specific Peptides for CHST10 Gene

O43529:

Post-translational modifications for CHST10 Gene

Glycosylation at Thr 66, Asn 99, Asn 228, and Asn 316
- NX_O43529
Modification sites at PhosphoSitePlus
- O43529

Other Protein References for CHST10 Gene

ENSEMBL proteins:

REFSEQ proteins:

NP_004845.1

Antibody Products

Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies

Browse R&D Systems for Antibodies

OriGene Antibodies for CHST10
- TA314920
Custom Antibody Services

Novus Biologicals Antibodies for CHST10

Abcam antibodies for CHST10

Browse Antibodies at Cloud-Clone Corp.

Invitrogen Antibodies for CHST10

antibodies-online Antibodies for CHST10: See all 34

GeneTex CHST10 antibody for CHST10

Santa Cruz Biotechnology (SCBT) Antibodies for CHST10

Protein Products

Browse Purified and Recombinant Proteins at EMD Millipore

R&D Systems Proteins and Enzymes for CHST10 (Carbohydrate Sulfotransferase 10/CHST10)

Browse Enzo Life Sciences for proteins

OriGene Purified Proteins for CHST10
Search Origene for MassSpec and Protein Over-expression Lysates for CHST10
Origene Custom Protein Services for CHST10

GenScript Custom Purified and Recombinant Proteins Services for CHST10

Novus Biologicals proteins and lysates for CHST10

Browse ProSpec Recombinant Proteins

Browse Proteins at Cloud-Clone Corp.

Search eBioscience for CHST10 related proteins

antibodies-online Proteins for CHST10: See all 8
Search antibodies-online for peptides

Search GeneTex for Proteins for CHST10

Abcam proteins for CHST10

Assay Products

Browse Kits and Assays available from EMD Millipore

Browse R&D Systems for biochemical assays

GenScript Custom Assay Services for CHST10

Browse Enzo Life Sciences for kits & assays

Browse Assay Kits at Cloud-Clone Corp.

Search eBioscience for CHST10 related elisas

antibodies-online Kits for CHST10: See all 3

Search for Assays for CHST10 at Abcam

Domains & Families for CHST10 Gene

Gene Families for CHST10 Gene

HGNC:

763 : Sulfotransferases, membrane-bound

Protein Domains for CHST10 Gene

InterPro:

ProtoNet:

O43529

Suggested Antigen Peptide Sequences for CHST10 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O43529

UniProtKB/Swiss-Prot:

CHSTA_HUMAN :

Belongs to the sulfotransferase 2 family.

Family:

Belongs to the sulfotransferase 2 family.

Function for CHST10 Gene

Molecular function for CHST10 Gene

UniProtKB/Swiss-Prot Function:

Catalyzes the transfer of sulfate to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides. Participates in biosynthesis of HNK-1 carbohydrate structure, a sulfated glucuronyl-lactosaminyl residue carried by many neural recognition molecules, which is involved in cell interactions during ontogenetic development and in synaptic plasticity in the adult. May be indirectly involved in synapse plasticity of the hippocampus, via its role in HNK-1 biosynthesis.

CHSTA_HUMAN,O43529

Enzyme Numbers (IUBMB) for CHST10 Gene

EC 2.8.2 ⁶³
EC 2.8.2.- ⁴

Phenotypes for CHST10 Gene

MGI mutant phenotypes for CHST10:

inferred from 2 alleles

GenomeRNAi human phenotypes for CHST10:

Animal Models for CHST10 Gene

MGI Knock Outs for CHST10:

Chst10 ^tm1Msch
Chst10 ^tm1Mifu

Animal Model Products

Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study

ViGene Biosciences lentiviral particle packaged cDNA for CHST10 gene
- LH845901
ViGene Biosciences ready-to-package AAV shRNAs for CHST10 gene
- SH845901
Search ViGene Biosciences for CHST10

CRISPR Products

OriGene CRISPR knockouts for CHST10
- KN203793
- KN303320

Santa Cruz Biotechnology (SCBT) CRISPR for CHST10

GenScript: Design CRISPR guide RNA sequences for CHST10

miRNA for CHST10 Gene

miRTarBase miRNAs that target CHST10

hsa-mir-143-3p (MIRT053640)

miRNA Products

Search ViGene Biosciences for CHST10

Inhibitory RNA Products

Origene siRNA, shRNA, mouse_rna, rat_shrna, and RNAi products in human, mouse, rat for CHST10
Browse OriGene Inhibitory RNA Products For CHST10

ViGene Biosciences ready-to-package AAV shRNAs for CHST10 gene
- SH845901

Search Santa Cruz Biotechnology (SCBT) for CHST10 siRNA/shRNA

No data available for Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CHST10 Gene

Localization for CHST10 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CHST10 Gene

Golgi apparatus membrane; Single-pass type II membrane protein.

O43529-CHSTA_HUMAN

Subcellular locations from

COMPARTMENTS

Jensen Localization Image for CHST10 Gene

Compartment	Confidence
golgi apparatus	5
extracellular	3
cytosol	2
endoplasmic reticulum	1
peroxisome	1

Gene Ontology (GO) - Cellular Components for CHST10 Gene

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016021	integral component of membrane	IEA	--

Pathways & Interactions for CHST10 Gene

SuperPathways for CHST10 Gene

More details on SuperPathways for CHST10

	Superpath	Contained pathways
1	Transport to the Golgi and subsequent modification	Transport to the Golgi and subsequent modification .81 Asparagine N-linked glycosylation .63	Post-translational protein modification .49 Metabolism of proteins .47
2	N-glycan antennae elongation in the medial/trans-Golgi	N-glycan antennae elongation in the medial/trans-Golgi 1	Reactions specific to the complex N-glycan synthesis pathway 1
3	Other types of O-glycan biosynthesis	Other types of O-glycan biosynthesis 1
4	Articular Cartilage Extracellular Matrix Pathway	Articular Cartilage Extracellular Matrix Pathway 1
5	Phase II conjugation	metapathway biotransformation .39

Pathways by source for CHST10 Gene

1 BioSystems pathway for CHST10 Gene

metapathway biotransformation

6 Reactome pathways for CHST10 Gene

1 KEGG pathway for CHST10 Gene

Other types of O-glycan biosynthesis

1 R&D Systems pathway for CHST10 Gene

Articular Cartilage Extracellular Matrix Pathway

Interacting Proteins for CHST10 Gene

http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000264249%0d%0a9606.ENSP00000431512%0d%0a — STRING Interaction Network Preview (showing 1 interactants - click image to see details)

Selected Interacting proteins: ENSP00000264249 O43529-CHSTA_HUMAN for CHST10 Gene via STRING I2D

Symbol	External ID(s)	Details
EEF1G	P26641 ²¹	I2D: score=1
HSF1	ENSP00000431512 ²⁰	STRING: ENSP00000431512

Gene Ontology (GO) - Biological Process for CHST10 Gene

None

No data available for SIGNOR curated interactions for CHST10 Gene

Drugs & Compounds for CHST10 Gene

(1) Drugs for CHST10 Gene - From: Novoseek

Name	Status	Disease Links	Group	Role	Mechanism of Action	Clinical Trials

(2) Additional Compounds for CHST10 Gene - From: Novoseek

Name	Synonyms	Role	CAS Number	PubChem IDs	PubMed IDs

Drug Products

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CHST10

Browse compounds at ApexBio

Transcripts for CHST10 Gene

mRNA/cDNA for CHST10 Gene

(7) REFSEQ mRNAs :

(5) Additional mRNA sequences :

(154) Selected AceView cDNA sequences:

(12) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CHST10 Gene

Carbohydrate sulfotransferase 10:

Hs.516370

Representative Sequences:

AF033827

CRISPR Products

OriGene CRISPR knockouts for CHST10
- KN203793
- KN303320

Santa Cruz Biotechnology (SCBT) CRISPR for CHST10

GenScript: Design CRISPR guide RNA sequences for CHST10

miRNA Products

Search ViGene Biosciences for CHST10

Inhibitory RNA Products

Origene siRNA, shRNA, mouse_rna, rat_shrna, and RNAi products in human, mouse, rat for CHST10
Browse OriGene Inhibitory RNA Products For CHST10

ViGene Biosciences ready-to-package AAV shRNAs for CHST10 gene
- SH845901

Search Santa Cruz Biotechnology (SCBT) for CHST10 siRNA/shRNA

Clone Products

OriGene clones in human for CHST10
OriGene ORF clones in human,mouse,rat for CHST10
Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling

GenScript: Next-day shipping cDNA clones in your preferred vector

Sino Biological Human cDNA Clone for CHST10

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat

Search Addgene for plasmids for CHST10

Flow Cytometry Products

eBioscience FlowRNA Probe Sets

Alternative Splicing Database (ASD) splice patterns (SP) for CHST10 Gene

ExUns:	1a	·	1b	·	1c	·	1d	·	1e	·	1f	^	2a	·	2b	·	2c	^	3a	·	3b	·	3c	^	4a	·	4b	^	5	^	6	^	7a	·	7b	^	8	^	9	^	10a	·	10b	^	11	^	12a	·	12b	·	12c	·
SP1:													-		-		-		-		-		-		-		-		-				-		-		-		-
SP2:													-		-		-		-		-		-		-		-		-						-
SP3:																	-		-		-		-		-		-		-				-		-		-		-
SP4:																													-				-		-		-		-
SP5:																																	-		-		-		-
SP6:													-		-		-		-		-		-		-		-		-				-		-		-		-						-
SP7:													-		-		-		-		-		-		-		-		-						-		-		-
SP8:																	-								-		-		-				-		-		-		-
SP9:																	-		-		-		-						-				-		-		-		-
SP10:																							-		-		-		-				-		-		-		-
SP11:													-		-		-		-		-		-		-		-		-
SP12:																			-		-		-						-
SP13:

ExUns:	12d	^	13a	·	13b	^	14a	·	14b
SP1:			-
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:

Relevant External Links for CHST10 Gene

GeneLoc Exon Structure for: CHST10
ECgene alternative splicing isoforms for: CHST10

Expression for CHST10 Gene

mRNA expression in normal human tissues for CHST10 Gene

mRNA expression by BioGPS for CHST10 Gene

Protein differential expression in normal tissues from HIPED for CHST10 Gene

This gene is overexpressed in Vitreous humor (67.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CHST10 Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for CHST10 Gene

Integrated proteomics: cell line protein expression from ProteomicsDB, MOPED and MaxQB for CHST10 Gene

SOURCE GeneReport for Unigene cluster for CHST10 Gene Hs.516370

mRNA Expression by UniProt/SwissProt for CHST10 Gene

O43529-CHSTA_HUMAN

Tissue specificity: In fetal tissues, it is predominantly expressed in brain, and weakly expressed in lung, kidney and liver. In adult, it is highly expressed in brain, testis, ovary, expressed at intermediate level in heart, pancreas, skeletal muscle, spleen and thymus, and weakly expressed in other tissues. In brain, it is expressed at higher level in the frontal lobe.

Protein tissue co-expression partners for CHST10 Gene

Primer Products

OriGene qPCR primer pairs for CHST10
- HP208110
OriGene qPCR primer pairs and template standards for CHST10
- HK201985

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for CHST10 Gene

Orthologs for CHST10 Gene

This gene was present in the common ancestor of animals.

Orthologs for CHST10 Gene

Organism	Taxonomy	Gene	Similarity	Type	Details
cow (Bos Taurus)	Mammalia	CHST10 ³⁵	86.04 (n) 91.45 (a)		511215 NM_001098011.1 NP_001091480.1
cow (Bos Taurus)	Mammalia	CHST10 ³⁶	91 (a)	OneToOne	11:5469350-5488597
dog (Canis familiaris)	Mammalia	CHST10 ³⁵	89.84 (n) 94.3 (a)		474555 XM_005626011.1 XP_005626068.1
dog (Canis familiaris)	Mammalia	CHST10 ³⁶	92 (a)	OneToOne	10:42311067-42339732
mouse (Mus musculus)	Mammalia	Chst10 ³⁵	86.61 (n) 91.01 (a)		98388 NM_145142.2 NP_660124.2
		Chst10 ¹⁶			38863867
		Chst10 ³⁶	87 (a)	OneToOne	1:38863877-38898160
chimpanzee (Pan troglodytes)	Mammalia	CHST10 ³⁵	99.44 (n) 99.16 (a)		459446 XM_001161408.2 XP_001161408.2
chimpanzee (Pan troglodytes)	Mammalia	CHST10 ³⁶	99 (a)	OneToOne	2A:100664883-100691373
rat (Rattus norvegicus)	Mammalia	Chst10 ³⁵	87.08 (n) 90.17 (a)		140568 NM_080397.1 NP_536322.1
oppossum (Monodelphis domestica)	Mammalia	CHST10 ³⁶	85 (a)	OneToOne	7:62362328-62416808
platypus (Ornithorhynchus anatinus)	Mammalia	-- ³⁶	81 (a)	OneToMany	Contig12817:964-19203
platypus (Ornithorhynchus anatinus)	Mammalia	-- ³⁶	93 (a)	OneToMany	Contig29276:5851-6390
chicken (Gallus gallus)	Aves	CHST10 ³⁵	78.28 (n) 85.96 (a)		395206 NM_001030343.1 NP_001025514.1
chicken (Gallus gallus)	Aves	CHST10 ³⁶	85 (a)	OneToOne	1:132462152-132478739
lizard (Anolis carolinensis)	Reptilia	CHST10 ³⁶	85 (a)	OneToOne	GL343456.1:625180-639748
tropical clawed frog (Silurana tropicalis)	Amphibia	chst10 ³⁵	71.31 (n) 76.42 (a)		100487586 XM_002943061.2 XP_002943107.1
tropical clawed frog (Silurana tropicalis)	Amphibia	Str.16232 ³⁵			142000134
African clawed frog (Xenopus laevis)	Amphibia	Xl.8239 ³⁵			48024128
zebrafish (Danio rerio)	Actinopterygii	chst10 ³⁵	65.15 (n) 67.05 (a)		445322 NM_001003779.1 NP_001003779.1
		Dr.11834 ³⁵			CA471403.1
		chst10 ³⁶	64 (a)	OneToOne	1:27013564-27028673
fruit fly (Drosophila melanogaster)	Insecta	CG13937 ³⁶	17 (a)	ManyToMany	3L:1876551-1883041
fruit fly (Drosophila melanogaster)	Insecta	CG14024 ³⁶	18 (a)	ManyToMany	2L:5311311-5314885
sea squirt (Ciona savignyi)	Ascidiacea	-- ³⁶	24 (a)	ManyToMany	reftig_49:372207-375222
		-- ³⁶	23 (a)	ManyToMany	reftig_4:1103598-1104879
		-- ³⁶	23 (a)	ManyToMany	reftig_77:1438721-1447664
		-- ³⁶	28 (a)	ManyToMany	reftig_77:1472514-1474647
		-- ³⁶	26 (a)	ManyToMany	reftig_9:3204589-3205389

Species with no ortholog for CHST10:

A. gosspyii yeast (Ashbya gossypii)
Actinobacteria (Mycobacterium tuberculosis)
African malaria mosquito (Anopheles gambiae)
Alicante grape (Vitis vinifera)
alpha proteobacteria (Wolbachia pipientis)
amoeba (Dictyostelium discoideum)
Archea (Pyrococcus horikoshii)
baker's yeast (Saccharomyces cerevisiae)
barley (Hordeum vulgare)
beta proteobacteria (Neisseria meningitidis)
bread mold (Neurospora crassa)
Chromalveolata (Phytophthora infestans)
common water flea (Daphnia pulex)
corn (Zea mays)
E. coli (Escherichia coli)
filamentous fungi (Aspergillus nidulans)
Firmicute bacteria (Streptococcus pneumoniae)
fission yeast (Schizosaccharomyces pombe)
green algae (Chlamydomonas reinhardtii)
honey bee (Apis mellifera)
K. lactis yeast (Kluyveromyces lactis)
loblloly pine (Pinus taeda)
malaria parasite (Plasmodium falciparum)
medicago trunc (Medicago Truncatula)
moss (Physcomitrella patens)
orangutan (Pongo pygmaeus)
pig (Sus scrofa)
rainbow trout (Oncorhynchus mykiss)
rice (Oryza sativa)
rice blast fungus (Magnaporthe grisea)
schistosome parasite (Schistosoma mansoni)
sea anemone (Nematostella vectensis)
sea urchin (Strongylocentrotus purpuratus)
sorghum (Sorghum bicolor)
soybean (Glycine max)
stem rust fungus (Puccinia graminis)
sugarcane (Saccharum officinarum)
thale cress (Arabidopsis thaliana)
tomato (Lycopersicon esculentum)
toxoplasmosis (Toxoplasma gondii)
Trichoplax (Trichoplax adhaerens)
wheat (Triticum aestivum)
worm (Caenorhabditis elegans)

Evolution for CHST10 Gene

ENSEMBL:: Gene Tree for CHST10 (if available)
TreeFam:: Gene Tree for CHST10 (if available)

Paralogs for CHST10 Gene

CHST9 ⁵
CHST13 ⁵
CHST11 ⁵
CHST14 ⁵
CHST12 ⁵
CHST8 ⁵

(4) SIMAP similar genes for CHST10 Gene using alignment to 8 proteins:

Variants for CHST10 Gene

Sequence variations from dbSNP and Humsavar for CHST10 Gene

SNP ID	Clin	Chr 02 pos	Sequence Context	Type
rs3748932	-	100,393,544(-)	TTGGG(A/G)ACCAC	reference, missense
rs35177621	-	100,406,618(-)	TCATG(G/T)TGGCT	reference, missense
rs1811415	--	100,399,139(-)	GCCAC(A/G)GAACG	intron-variant
rs1057055	--	100,392,914(-)	CCGTT(C/T)CCTTC	utr-variant-3-prime
rs1057056	--	100,392,620(-)	CAGGG(A/G)TCCAT	utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for CHST10 Gene

Variant ID	Type	Subtype	PubMed ID
nsv874701	CNV	Gain	21882294
nsv829583	CNV	Gain	20364138

Variation tolerance for CHST10 Gene

Residual Variation Intolerance Score: 73.7% of all genes are more intolerant (likely to be disease-causing)

Gene Damage Index Score: 8.49; 85.84% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for CHST10 Gene

Disorders for CHST10 Gene

Relevant External Links for CHST10

Genetic Association Database (GAD): CHST10
Human Genome Epidemiology (HuGE) Navigator: CHST10
Atlas of Genetics and Cytogenetics in Oncology and Haematology:: CHST10

No disorders were found for CHST10 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CHST10 Gene

Publications for CHST10 Gene

Structure and function of HNK-1 sulfotransferase. Identification of donor and acceptor binding sites by site-directed mutagenesis. (PMID: 10464296) Ong E. … Fukuda M. (J. Biol. Chem. 1999) ³ ⁴ ²³ ⁶⁷
Molecular cloning and characterization of chondroitin-4-O- sulfotransferase-3. A novel member of the HNK-1 family of sulfotransferases. (PMID: 12080076) Kang H.-G. … Schachner M. (J. Biol. Chem. 2002) ² ³ ²³
Mechanism of regulation and suppression of melanoma invasiveness by novel retinoic acid receptor-gamma target gene carbohydrate sulfotransferase 10. (PMID: 19470764) Zhao X. … Spanjaard R.A. (Cancer Res. 2009) ³ ²³
Expression cloning of a human sulfotransferase that directs the synthesis of the HNK-1 glycan on the neural cell adhesion molecule and glycolipids. (PMID: 9478973) Ong E. … Fukuda M. (J. Biol. Chem. 1998) ³ ²³
The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) ³