Aliases for CHRD Gene
External Ids for CHRD Gene
- HGNC: 1949
- Entrez Gene: 8646
- Ensembl: ENSG00000090539
- OMIM: 603475
- UniProtKB: Q9H2X0
Previous GeneCards Identifiers for CHRD Gene
- GC03P180570
- GC03P185091
- GC03P185499
- GC03P185419
- GC03P185421
- GC03P185580
- GC03P184097
- GC03P181483
Summaries for CHRD Gene
-
This gene encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. The encoded protein may also have roles in organogenesis and during adulthood. It has been suggested that this gene could be a candidate gene for Cornelia de Lange syndrome. Reduced expression of this gene results in enhanced bone regeneration. Alternative splicing results in multiple transcript variants. Other alternative splice variants have been described but their full length sequence has not been determined. [provided by RefSeq, Jan 2015]
GeneCards Summary for CHRD Gene
CHRD (Chordin) is a Protein Coding gene. Diseases associated with CHRD include Cornelia De Lange Syndrome. Among its related pathways are Mesodermal Commitment Pathway and TGF-beta signaling pathway (KEGG). GO annotations related to this gene include heparin binding and syndecan binding. An important paralog of this gene is CHRDL2.
UniProtKB/Swiss-Prot for CHRD Gene
-
Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes (By similarity).
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CHRD Gene
Genomics for CHRD Gene
Regulatory Elements for CHRD Gene
- Transcription factor binding sites by QIAGEN in the CHRD gene promoter:
Regulatory Element Products
Genomic Location for CHRD Gene
- Chromosome:
- 3
- Start:
- 184,380,073 bp from pter
- End:
- 184,390,736 bp from pter
- Size:
- 10,664 bases
- Orientation:
- Plus strand
Genomic View for CHRD Gene
- Cytogenetic band:
-
- 3q27.1 by Ensembl
- 3q27.1 by Entrez Gene
- 3q27.1 by HGNC
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CHRD Gene
Proteins for CHRD Gene
-
Protein details for CHRD Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9H2X0-CHRD_HUMAN
- Recommended name:
- Chordin
- Protein Accession:
- Q9H2X0
- O95254
- Q2M1I8
- Q6UW83
- Q9H2D3
- Q9H2W8
- Q9H2W9
- Q9P0Z2
- Q9P0Z3
- Q9P0Z4
- Q9P0Z5
Protein attributes for CHRD Gene
- Size:
- 955 amino acids
- Molecular mass:
- 102032 Da
- Quaternary structure:
-
- Interacts with TWSG1 and/or BMP4.
Protein Expression for CHRD Gene
Post-translational modifications for CHRD Gene
- Cleaved by tolloid proteases; cleavage participates in dorsoventral patterning during early development.
- Glycosylation at posLast=217217, Asn351, posLast=365365, and Asn434
- Modification sites at PhosphoSitePlus
Other Protein References for CHRD Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for CHRD (Chordin)
-
Custom Antibody ServicesOriGene Antibodies for CHRD
- Novus Biologicals Antibodies for CHRD
-
Cloud-Clone Corp. Antibodies for CHRD
- Invitrogen Antibodies for CHRD
- antibodies-online Antibodies for CHRD: See all 64
- Search GeneTex for Antibodies for CHRD
Protein Products
-
OriGene Purified Proteins for CHRD
- Search Origene for MassSpec and Protein Over-expression Lysates for CHRD
- Origene Custom Protein Services for CHRD
-
Cloud-Clone Corp. Proteins for CHRD
- antibodies-online Proteins for CHRD: See all 4
- Search antibodies-online for peptides
- Search GeneTex for Proteins for CHRD
No data available for DME Specific Peptides for CHRD Gene
Domains & Families for CHRD Gene
Protein Domains for CHRD Gene
Suggested Antigen Peptide Sequences for CHRD Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9H2X0- Family:
-
- Belongs to the chordin family.
No data available for Gene Families for CHRD Gene
Function for CHRD Gene
Molecular function for CHRD Gene
- GENATLAS Biochemistry:
- chordin,developmental protein,highly conserved,inhibiting the ventralizing activity of bone morphogenetic proteins,active during gastrulation,expressed in fetal and adult liver and cerebellum
- UniProtKB/Swiss-Prot Function:
- Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes (By similarity).
LifeMap Function Summary for CHRD Gene
- Epiblast
- Primitive Streak
- Ectoderm
- Neural Ectoderm
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 21988832 |
| GO:0008201 | heparin binding | IEA | -- |
| GO:0019955 | cytokine binding | NAS | 16449796 |
| GO:0045545 | syndecan binding | IEA | -- |
Phenotypes for CHRD Gene
- MGI mutant phenotypes for CHRD:
-
inferred from 2 alleles
- mortality/aging
- cellular phenotype
- behavior/neurological phenotype
- normal phenotype
- growth/size/body region phenotype
- immune system phenotype
- muscle phenotype
- nervous system phenotype
- homeostasis/metabolism phenotype
- cardiovascular system phenotype
- respiratory system phenotype
- digestive/alimentary phenotype
- reproductive system phenotype
- endocrine/exocrine gland phenotype
- vision/eye phenotype
- hearing/vestibular/ear phenotype
- skeleton phenotype
- embryo phenotype
- hematopoietic system phenotype
- renal/urinary system phenotype
- craniofacial phenotype
- taste/olfaction phenotype
- GenomeRNAi human phenotypes for CHRD:
Animal Models for CHRD Gene
- MGI Knock Outs for CHRD:
-
- Chrd tm1Emdr
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CHRD
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CHRD gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CHRD gene
- Search ViGene Biosciences for CHRD
CRISPR Products
-
OriGene CRISPR knockouts for CHRD
-
Santa Cruz Biotechnology (SCBT) CRISPR for CHRD
- GenScript: Design CRISPR guide RNA sequences for CHRD
miRNA Products
- Search ViGene Biosciences for CHRD
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CHRD
- Browse OriGene Inhibitory RNA Products For CHRD
-
ViGene Biosciences ready-to-package AAV shRNAs for CHRD gene
Clone Products
- Sino Biological Human cDNA Clone for CHRD
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CHRD
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CHRD
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for CHRD
-
ViGene Biosciences adenoviral particle packaged cDNA for CHRD gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CHRD gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CHRD gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for CHRD Gene
Localization for CHRD Gene
Subcellular locations from UniProtKB/Swiss-Prot for CHRD Gene
- Secreted.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA | -- |
| GO:0005615 | extracellular space | NAS | 16449796 |
Pathways & Interactions for CHRD Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | TGF-beta signaling pathway (KEGG) | ||
| 2 | Signaling by BMP | ||
| 3 | Mesodermal Commitment Pathway | ||
Pathways by source for CHRD Gene
1 GeneTex pathway for CHRD Gene
2 BioSystems pathways for CHRD Gene
1 KEGG pathway for CHRD Gene
Interacting Proteins for CHRD Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001501 | skeletal system development | TAS | 9782094 |
| GO:0001649 | osteoblast differentiation | IEA | -- |
| GO:0001702 | gastrulation with mouth forming second | IEA | -- |
| GO:0001707 | mesoderm formation | IEA | -- |
| GO:0002053 | positive regulation of mesenchymal cell proliferation | IMP | 18533030 |
No data available for SIGNOR curated interactions for CHRD Gene
Transcripts for CHRD Gene
mRNA/cDNA for CHRD Gene
- (15) REFSEQ mRNAs :
- (14) Additional mRNA sequences :
- (51) Selected AceView cDNA sequences:
- (17) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for CHRD
-
Santa Cruz Biotechnology (SCBT) CRISPR for CHRD
- GenScript: Design CRISPR guide RNA sequences for CHRD
miRNA Products
- Search ViGene Biosciences for CHRD
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CHRD
- Browse OriGene Inhibitory RNA Products For CHRD
-
ViGene Biosciences ready-to-package AAV shRNAs for CHRD gene
Clone Products
- Sino Biological Human cDNA Clone for CHRD
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CHRD
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CHRD
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | · | 10c | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP13: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP14: |
| ExUns: | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20a | · | 20b | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25a | · | 25b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||||
| SP5: | - | - | |||||||||||||||||||||||||
| SP6: | - | - | |||||||||||||||||||||||||
| SP7: | |||||||||||||||||||||||||||
| SP8: | |||||||||||||||||||||||||||
| SP9: | |||||||||||||||||||||||||||
| SP10: | |||||||||||||||||||||||||||
| SP11: | |||||||||||||||||||||||||||
| SP12: | |||||||||||||||||||||||||||
| SP13: | |||||||||||||||||||||||||||
| SP14: |
Expression for CHRD Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Primitive Streak (Early Embryonic Tissues)
- Primitive Streak Cells Anterior Primitive Streak
- Primitive Streak Cells Primitive Streak
- Prechordal Plate Cells Prechordal Plate
- Notochord Cells Notochord
- Primitive Node Cells Primitive Node
-
Epiblast (Early Embryo)
- Primitive Streak Cells Anterior Primitive Streak
- Early-Gastrula Organizer Epiblast
- Prechordal Plate Cells Prechordal Plate
- Primitive Node Cells Primitive Node
- Brain (Nervous System)
- Neural Tube (Nervous System)
-
Cartilage (Muscoskeletal System)
- Notochord Cells Notochord
- Gut Tube (Gastrointestinal Tract)
- Lung (Respiratory System)
mRNA differential expression in normal tissues according to GTEx for CHRD Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CHRD Gene
NURSA nuclear receptor signaling pathways regulating expression of CHRD Gene:
CHRDSOURCE GeneReport for Unigene cluster for CHRD Gene:
Hs.166186mRNA Expression by UniProt/SwissProt for CHRD Gene:
Q9H2X0-CHRD_HUMANEvidence on tissue expression from TISSUES for CHRD Gene
- Nervous system(4.1)
Primer Products
-
OriGene qPCR primer pairs for CHRD
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for CHRD Gene
Orthologs for CHRD Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CHRD 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | CHRD 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | CHRD 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Chrd 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Chrd 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | CHRD 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | CHRD 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | CHRD 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | CHRD 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | chrd 34 |
|
||
| Str.2204 34 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | LOC398045 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | chd 34 35 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | sog 36 34 35 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP000472 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToOne |
- Species where no ortholog for CHRD was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for CHRD Gene
(1) SIMAP similar genes for CHRD Gene using alignment to 3 proteins:
Variants for CHRD Gene
| SNP ID | Clin | Chr 03 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs145871696 | Likely benign | 184,383,572(+) | GGAGA(C/G/T)CAAGC | nc-transcript-variant, reference, missense | |
| rs886058219 | Uncertain significance | 184,378,144(-) | ACATG(A/T)CTTCC | intron-variant, upstream-variant-2KB, reference, missense, utr-variant-5-prime | |
| rs1000875801 | -- | 184,381,657(+) | TGGTT(C/G)AGGCT | intron-variant, upstream-variant-2KB | |
| rs1001837170 | -- | 184,388,070(+) | CCTTT(A/G)GGTTG | intron-variant | |
| rs1002536924 | -- | 184,378,174(+) | TCCAC(A/G)GCAGC | intron-variant, upstream-variant-2KB, reference, missense, utr-variant-5-prime |
Relevant External Links for CHRD Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CHRD Gene
Disorders for CHRD Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| cornelia de lange syndrome |
|
|
Relevant External Links for CHRD
No data available for UniProtKB/Swiss-Prot and Genatlas for CHRD Gene
Publications for CHRD Gene
- The human chordin gene encodes several differentially expressed spliced variants with distinct BMP opposing activities. (PMID: 11472837) Millet C. … Francois V. (Mech. Dev. 2001) 2 3 4 22 64
- Coding sequence and expression patterns of mouse chordin and mapping of the cognate mouse chrd and human CHRD genes. (PMID: 9782094) Pappano W.N. … Greenspan D.S. (Genomics 1998) 2 3 4 22 64
- BMP-binding modules in chordin: a model for signalling regulation in the extracellular space. (PMID: 10648240) Larrain J. … De Robertis E.M. (Development 2000) 3 4 22 64
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 46 64
- High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. (PMID: 19453261) Yerges L.M. … Zmuda J.M. (J. Bone Miner. Res. 2009) 3 46 64
Products for CHRD Gene
- R&D Systems Antibodies for CHRD (Chordin)
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- Custom Antibody ServicesOriGene Antibodies for CHRD
- Browse OriGene ELISA Kits
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- OriGene Purified Proteins for CHRD
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- Origene Custom Protein Services for CHRD
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CHRD
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- OriGene qPCR primer pairs for CHRD
- OriGene CRISPR knockouts for CHRD
- OriGene ORF clones in human for CHRD
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Next-day shipping cDNA ORF clone for CHRD in any vector
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- GenScript: Design CRISPR guide RNA sequences for CHRD
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for CHRD
- Novus Biologicals proteins and lysates for CHRD
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Cloud-Clone Corp. Antibodies for CHRD
- Cloud-Clone Corp. Proteins for CHRD
- Cloud-Clone Corp Assay Kits for CHRD
- antibodies-online Antibodies for CHRD: See all 64
- antibodies-online Kits for CHRD: See all 9
- antibodies-online Proteins for CHRD: See all 4
- Search antibodies-online for peptides
- Search GeneTex for Antibodies for CHRD
- Search GeneTex for Proteins for CHRD
- ViGene Biosciences adenoviral particle packaged cDNA for CHRD gene
- ViGene Biosciences lentiviral particle packaged cDNA for CHRD gene
- ViGene Biosciences ready-to-package AAV shRNAs for CHRD gene
- Search ViGene Biosciences for CHRD
- Horizon Cell Lines for CHRD
- Cyagen custom Knockout/knockin (KOKI) mouse models for CHRD
- VectorBuilder custom plasmid, inducible vectors for CHRD
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CHRD
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for CHRD Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer




