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CHPF2 Gene

protein-coding   GIFtS: 53
GCID: GC07P150929

Chondroitin Polymerizing Factor 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Chondroitin Polymerizing Factor 21 2 3     chPF-22
Chondroitin Glucuronyltransferase2 3     Chondroitin Sulfate Glucuronyltransferase2
Chondroitin Synthase 32 3     Chondroitin Synthase-32
ChSy-32 3     CHSY33
N-Acetylgalactosaminyl-Proteoglycan 3-Beta-Glucuronosyltransferase2 3     CSGLCAT3
CSGlcAT2 5     CSGlcA-T3
KIAA14023 5     ChPF-23
CSGLCA-T2     EC 2.4.1.2263

External Ids:    HGNC: 292701   Entrez Gene: 544802   Ensembl: ENSG000000331007   OMIM: 6080375   UniProtKB: Q9P2E53   

Export aliases for CHPF2 gene to outside databases

Previous GC identifers: GC07P150562 GC07P144741


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CHPF2 Gene:
CHPF2 (chondroitin polymerizing factor 2) is a protein-coding gene. Diseases associated with CHPF2 include morquio syndrome b, and sly syndrome. GO annotations related to this gene include N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity. An important paralog of this gene is CSGALNACT1.

UniProtKB/Swiss-Prot: CHPF2_HUMAN, Q9P2E5
Function: Transfers glucuronic acid (GlcUA) from UDP-GlcUA to N-acetylgalactosamine residues on the non-reducing
end of the elongating chondroitin polymer. Has no N-acetylgalactosaminyltransferase activity




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000007.14  NC_018918.2  NT_007933.16  
Regulatory elements:
   Search for regulatory transcription factor binding sites for CHPF2
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): CHPF2 promoter sequence
   Search Chromatin IP Primers for CHPF2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CHPF2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q36.1   Ensembl cytogenetic band:  7q36.1   HGNC cytogenetic band: 7q36.1

CHPF2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CHPF2 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P150929:  view genomic region     (about GC identifiers)

Start:
150,929,575 bp from pter      End:
150,935,908 bp from pter
Size:
6,334 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 150,259,122-150,265,442     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: CHPF2_HUMAN, Q9P2E5 (See protein sequence)
Recommended Name: Chondroitin sulfate glucuronyltransferase  
Size: 772 amino acids; 85948 Da
Sequence caution: Sequence=BAA92640.1; Type=Erroneous initiation;
Secondary accessions: B2DBD8 Q6P2I4 Q6UXD2
Alternative splicing: 2 isoforms:  Q9P2E5-1   Q9P2E5-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CHPF2: NX_Q9P2E5

Explore proteomics data for CHPF2 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn121, Asn342
  • Modification sites at PhosphoSitePlus

  • See CHPF2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001271224.1  NP_061888.1  

    ENSEMBL proteins: 
     ENSP00000419769   ENSP00000418914   ENSP00000035307   ENSP00000420204  
    Reactome Protein details: Q9P2E5

    CHPF2 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    B3GT: Beta 3-glycosyltransferases
    B4GT: Beta 4-glycosyltransferases

    1 InterPro protein domain:
     IPR008428 Chond_GalNAc

    Graphical View of Domain Structure for InterPro Entry Q9P2E5

    ProtoNet protein and cluster: Q9P2E5

    UniProtKB/Swiss-Prot: CHPF2_HUMAN, Q9P2E5
    Similarity: Belongs to the chondroitin N-acetylgalactosaminyltransferase family


    CHPF2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CHPF2_HUMAN, Q9P2E5
    Function: Transfers glucuronic acid (GlcUA) from UDP-GlcUA to N-acetylgalactosamine residues on the non-reducing
    end of the elongating chondroitin polymer. Has no N-acetylgalactosaminyltransferase activity
    Catalytic activity: UDP-alpha-D-glucuronate +
    N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan = UDP +
    beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan

         Enzyme Number (IUBMB): EC 2.4.1.2261

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016757transferase activity, transferring glycosyl groups ----
    GO:0016758transferase activity, transferring hexosyl groups ----
    GO:0050510N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity IEA--
         
    CHPF2 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Chpf2 (no phenotypes)

    CHPF2 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Chpf2tm1Lex for CHPF2

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CHPF2
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CHPF2

    miRNA
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    miRTarBase miRNAs that target CHPF2:
    hsa-mir-339-5p (MIRT042782), hsa-let-7b-5p (MIRT005223), hsa-mir-671-5p (MIRT039288), hsa-mir-671-3p (MIRT037777), hsa-mir-10b-5p (MIRT047492), hsa-mir-125b-5p (MIRT045967), hsa-mir-193b-3p (MIRT041558), hsa-mir-766-3p (MIRT039052), hsa-mir-98-5p (MIRT027616)

    Block miRNA regulation of human, mouse, rat CHPF2 using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate CHPF2:
    hsa-miR-298 hsa-miR-3143 hsa-miR-3120-3p hsa-miR-543
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CHPF2_HUMAN, Q9P2E5: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    golgi apparatus5
    cytosol1
    endoplasmic reticulum1
    extracellular1
    lysosome1
    mitochondrion1
    nucleus1
    plasma membrane1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane TAS--
    GO:0016020membrane ----
    GO:0016021integral component of membrane IEA--
    GO:0032580Golgi cisterna membrane IEA--

    CHPF2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for CHPF2 About                                                                                                See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1MPS VI - Maroteaux-Lamy syndrome
    MPS VI - Maroteaux-Lamy syndrome0.45
    MPS II - Hunter syndrome0.45
    MPS IIIC - Sanfilippo syndrome C0.45
    Glycosaminoglycan metabolism0.45
    MPS IV - Morquio syndrome A0.45
    MPS IV - Morquio syndrome B0.45
    Mucopolysaccharidoses0.45
    MPS VII - Sly syndrome0.45
    2Chondroitin sulfate/dermatan sulfate metabolism
    Chondroitin sulfate/dermatan sulfate metabolism0.51
    Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate0.00
    Chondroitin sulfate biosynthesis0.41
    3Metabolism
    Metabolism0.38
    Metabolic pathways0.38
    4dermatan sulfate biosynthesis
    dermatan sulfate biosynthesis
    chondroitin and dermatan biosynthesis0.00
    5Disease
    Disease

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3 BioSystems Pathways for CHPF2
        chondroitin and dermatan biosynthesis
    chondroitin sulfate biosynthesis
    dermatan sulfate biosynthesis

    1 Reactome Pathway for CHPF2
        Chondroitin sulfate biosynthesis


    2 Kegg Pathways  (Kegg details for CHPF2):
        Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
    Metabolic pathways


    CHPF2 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CHPF2
    Interactions:

        Search GeneGlobe Interaction Network for CHPF2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    Selected Interacting proteins for CHPF2 (ENSP000000353074) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EXOSC10ENSP000003661354STRING: ENSP00000366135
    EXOSC6ENSP000003985974STRING: ENSP00000398597
    CHPFENSP000002437764STRING: ENSP00000243776
    CHSY1ENSP000002541904STRING: ENSP00000254190
    CHSY3ENSP000003026294STRING: ENSP00000302629
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process TAS--
    GO:0030203glycosaminoglycan metabolic process TAS--
    GO:0030204chondroitin sulfate metabolic process TAS--
    GO:0030206chondroitin sulfate biosynthetic process TAS--
    GO:0044281small molecule metabolic process TAS--

    CHPF2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CHPF2

    2 HMDB Compounds for CHPF2    About this table
    CompoundSynonyms CAS #PubMed Ids
    Uridine 5'-diphosphate5'-UDP (see all 9)58-98-0--
    Uridine diphosphate glucuronic acidUDP glucuronate (see all 41)2616-64-0--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for CHPF2 gene (2 alternative transcripts): 
    NM_001284295.1  NM_019015.2  

    Unigene Cluster for CHPF2:

    Chondroitin polymerizing factor 2
    Hs.647084  [show with all ESTs]
    Unigene Representative Sequence: BC052944
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000482173 ENST00000495645(uc003wjq.1) ENST00000035307(uc003wjr.1)
    ENST00000465601
    miRNA
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    hsa-miR-298 hsa-miR-3143 hsa-miR-3120-3p hsa-miR-543
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Additional mRNA sequence: 

    AB037823.1 AB095812.1 AK025885.1 AK025897.1 AK056331.1 AY358407.1 BC052944.1 BC064509.1 

    7 DOTS entries:

    DT.95162255  DT.100823980  DT.99976728  DT.100042137  DT.100823978  DT.97821977  DT.95162265 

    Selected AceView cDNA sequences (see all 198):

    CN479495 AI620649 BU154833 AI272323 AI868588 BM874161 BF594067 AI475193 
    BQ576140 F09189 AI569467 AI819341 BE302778 AI139595 BM873701 AK025897 
    AB037823 AW082159 BE207563 BE206147 CB242955 BX369272 CF529167 AI191668 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for CHPF2    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5
    SP1:                                          
    SP2:                                          
    SP3:              -                           


    ECgene alternative splicing isoforms for CHPF2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CHPF2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTTCTGCCA
    CHPF2 Expression
    About this image

    CHPF2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CHPF2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.647084

    UniProtKB/Swiss-Prot: CHPF2_HUMAN, Q9P2E5
    Tissue specificity: Ubiquitous. Highly expressed in placenta, small intestine and pancreas

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHPF2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for CHPF2 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Chpf21 , 5 chondroitin polymerizing factor 21, 5 88.42(n)1
    93.68(a)1
      5 (11.93 cM)5
    1009101  NM_133913.21  NP_598674.21 
     245867415 
    chicken
    (Gallus gallus)
    Aves CHPF21 chondroitin polymerizing factor 2 65.55(n)
    67.91(a)
      426039  XM_423717.4  XP_423717.3 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    55(a)
    1 → many
    1(94644949-94667323)
    zebrafish
    (Danio rerio)
    Actinopterygii chpf21 chondroitin polymerizing factor 2 61.74(n)
    59.39(a)
      100000654  XM_001337169.4  XP_001337205.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG433136
    --
    27(a)
    1 → many
    X(12990125-13006475)
    worm
    (Caenorhabditis elegans)
    Secernentea mig-226
    Protein MIG-22, isoform a
    24(a)
    1 → many
    III(8763291-8767342) WBGene00003253


    ENSEMBL Gene Tree for CHPF2 (if available)
    TreeFam Gene Tree for CHPF2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CHPF2 gene
    CSGALNACT12  CHSY32  CHPF2  B4GALNT32  CSGALNACT22  CHSY12  B4GALNT42  
    1 SIMAP similar gene for CHPF2 using alignment to 4 protein entries:     CHPF2_HUMAN (see all proteins):
    CHPF

    CHPF2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CHPF2 (see all 155)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs27924321,2
    C,F,A,H--150927763(+) TTTTTT/CAACTC 1 -- us2k1 tfbs318Minor allele frequency- C:0.16NS EA NA WA CSA 2337
    rs774881961,2
    F--150927850(+) ACAGCG/ACTGGT 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1410263481,2
    --150928107(+) CCAATA/GTTCCA 1 -- us2k10--------
    rs737271241,2
    C,F--150928177(+) ATAGCC/TTAACT 1 -- us2k13Minor allele frequency- T:0.12WA CSA 122
    rs1151282181,2
    C,F--150928233(+) AAAGAA/GTAAAA 1 -- us2k11Minor allele frequency- G:0.02WA 118
    rs1853070401,2
    C--150928306(+) TAGTAG/TTTATG 1 -- us2k10--------
    rs1900009151,2
    --150928387(+) CCAGTC/TCTCCA 1 -- us2k10--------
    rs1809287751,2
    --150928538(+) AGGCAC/TATCAG 1 -- us2k10--------
    rs47260091,2
    C,F,A,H--150928545(+) TCAGAT/CGATTA 1 -- us2k123Minor allele frequency- C:0.43NA NS EA WA CSA 2462
    rs1448860461,2
    --150928551(+) GATTAC/TAACCA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CHPF2 (150929575 - 150935908 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for CHPF2:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv435860CNV Deletion17901297
    nsv889487CNV Loss21882294
    nsv889488CNV Loss21882294
    nsv889476CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608037    OMIM disorders: --

    4 diseases for CHPF2:    About MalaCards
    morquio syndrome b    sly syndrome    mucopolysaccharidoses    colorectal cancer


    CHPF2 for disorders           About GeneDecksing


    Export disorders for CHPF2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CHPF2 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with CHPF2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of chondroitin sulfate glucuronyltransferase as chondroitin synthase-3 involved in chondroitin polymerization: chondroitin polymerization is achieved by multiple enzyme complexes consisting of chondroitin synthase family members. (PubMed id 18316376)1, 2, 3, 9 Izumikawa T....Kitagawa H. (J. Biol. Chem. 2008)
    2. Molecular cloning and characterization of a novel chondroitin sulfate glucuronyltransferase that transfers glucuronic acid to N- acetylgalactosamine. (PubMed id 12145278)1, 2, 3 Gotoh M.... Narimatsu H. (J. Biol. Chem. 2002)
    3. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2000)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    6. Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells. (PubMed id 22268729)1 Liu B....Wang L.S. (J. Proteome Res. 2012)
    7. Chondroitin synthases I, II, III and chondroitin sulfate glucuronyltransferase expression in colorectal cancer. (PubMed id 21468578)1 Kalathas D....Vynios D.H. (Mol Med Rep 2011)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. Chondroitin sulfate synthase-2. Molecular cloning and characterization of a novel human glycosyltransferase homologous to chondroitin sulfate glucuronyltransferase, which has dual enzymatic activities. (PubMed id 12761225)9 Yada T.... Kimata K. (J. Biol. Chem. 2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54480 HGNC: 29270 AceView: CSGlcA-T Ensembl:ENSG00000033100 euGenes: HUgn54480
    ECgene: CHPF2 Kegg: 54480 H-InvDB: CHPF2

    (According to HUGE)
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    HUGE: KIAA1402

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CHPF2 Pharmacogenomics, SNPs, Pathways
    GGDBhttp://jcggdb.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=CHPF2

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CHPF2 gene:
    Search GeneIP for patents involving CHPF2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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