CHP2 Gene
protein-coding GIFtS: 45
GCID: GC16P023765
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|
calcineurin-like EF-hand protein 2
| |
Aliases
for CHP2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Calcineurin-Like EF-Hand Protein 21 2 | | Hepatocellular Carcinoma-Associated Antigen 5202 3 | | Calcineurin B Homologous Protein 22 | | Calcineurin-Like EF Hand Protein 22 | | Hepatocellular Carcinoma Antigen Gene 5202 | | HCA5203 |
Export aliases for CHP2 gene to outside databasesPrevious GC identifers: GC16P023674 GC16P021855 |
Summaries
for CHP2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: CHP2_HUMAN, O43745Function: Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+)exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protectingcells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growthby increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFATsignaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus
|
Genomic Views
for CHP2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010393.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CHP2 gene promoter:
AhR Spz1 GATA-3 POU3F2 Evi-1 AREB6 PPAR-alpha SRY c-Myb Sox9
Other transcription factors
Search SABiosciences Chromatin IP Primers for CHP2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHP2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p12.2 Ensembl cytogenetic band: 16p12.2 HGNC cytogenetic band: 16p12.2CHP2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P023765: view genomic region
(about GC identifiers)
Start:
|
23,765,948 bp from pter |
End:
|
23,770,272 bp from pter |
Size:
|
4,325 bases |
Orientation:
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plus strand |
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Proteins
for CHP2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CHP2_HUMAN, O43745 (See
protein sequence)Recommended Name: Calcineurin B homologous protein 2 Size: 196 amino acids; 22452 Da
Subunit: Interacts with PPP3CA. Interacts with SLC9A1/NHE1; the interaction occurs in a calcium-dependent manner
Subcellular location: Nucleus. Cytoplasm. Cell membrane. Note=Predominantly localized in a juxtanuclear region.Colocalizes with SLC9A3 in the juxtanuclear region and at the plasma membrane (By similarity). Exported from thenucleus to the cytoplasm through a nuclear export signal (NES) pathway. May shuttle between nucleus and cytoplasm
1 PDB 3D structure from  and Proteopedia  for CHP2:2BEC (3D)
Explore the universe of human proteins at neXtProt for CHP2: NX_O43745
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O43745
CHP2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_071380.1
ENSEMBL proteins: ENSP00000300113
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
CHP2 for ontologies About GeneDecksing
CHP2 Antibody Products:
Assay Products for CHP2: |
Protein
Domains /
Families
for CHP2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CHP2 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O43745ProtoNet protein and cluster: O43745 UniProtKB/Swiss-Prot: CHP2_HUMAN, O43745Similarity: Belongs to the calcineurin regulatory subunit family. CHP subfamilySimilarity: Contains 4 EF-hand domains |
Function
for CHP2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CHP2_HUMAN, O43745Function: Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+)exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protectingcells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growthby increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFATsignaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHP2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHP2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for CHP2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHP2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHP2 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005509 | calcium ion binding |
IDA | -- | | GO:0005515 | protein binding |
IPI | -- |
CHP2 for ontologies About GeneDecksing
|
Pathways & Interactions
for CHP2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/14 super-pathways (see all 14) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | B cell receptor signaling pathway | | | 2 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | | | 3 | Tuberculosis | | | 4 | Long-term potentiation | | | 5 | Natural killer cell mediated cytotoxicity | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for CHP2
5/15 
Kegg Pathways (Kegg details for CHP2) (see all 15):
CHP2 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CHP2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/37 Interacting proteins for CHP2 (O437452, 3 ENSP000003001134) via UniProtKB, MINT, STRING, and/or I2D (see all 37)About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table
CHP2 for ontologies About GeneDecksing
|
Drugs & Compounds
for CHP2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CHP2
Search CenterWatch for drugs/clinical trials and news about CHP2
|
Transcripts
for CHP2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CHP2 gene: NM_022097.2 Unigene Cluster for CHP2: Calcineurin-like EF-hand protein 2 Hs.178589 [show with all ESTs]Unigene Representative Sequence: AF1460191 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000300113(uc002dmb.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHP2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHP2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CHP2 (NM_022097) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CHP2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHP2 |
Additional cDNA sequence: AF146019.1 AK096977.1 AK290253.1 AK313062.1 2 DOTS entries: DT.208555 DT.99930779 24/37 AceView cDNA sequences (see all 37): BF056925 BF223890 BX351351 AI675204 BX483271 AW051613 AA514619 AA889355 AW004627 AI880669 BI754025 AI826786 AI659333 BX371534 BV191042 AA298640 AA397980 AI273289 AF146019 BG152541 AA435717 AI653000 AA527435 NM_022097
GeneLoc Exon Structure
|
Expression
for CHP2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CHP2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTAGGATGAT
About this image
See CHP2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CHP2
SOURCE GeneReport for Unigene cluster: Hs.178589
UniProtKB/Swiss-Prot: CHP2_HUMAN, O43745Tissue specificity: Expressed in malignantly transformed cells but not detected in normal tissues
SABiosciences Custom PCR Arrays for CHP2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHP2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CHP2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHP2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHP2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHP2 |
Orthologs
for CHP2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CHP2 gene from 5/19 species (see all 19) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
zebrafish
(Danio rerio) |
Actinopterygii |
chp21 |
calcineurin-like EF hand protein 2 |
64.95(n)
58.76(a) |
|
327599 NM_199836.1 NP_956130.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
elm6 |
ethanol sensitive with low memory |
49(a) |
1 → many |
3R(1478555-1480613) |
worm
(Caenorhabditis elegans) |
Secernentea |
pbo-11 |
Protein PBO-1 |
53.08(n)
47.28(a) |
|
175385 NM_065200.2 NP_497601.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT3G184306 |
EF-hand, calcium binding motif-containing protein |
29(a) |
1 → many |
3(6325915-6327692) |
rice
(Oryza sativa) |
Liliopsida |
-- |
EF hand family protein, putative, expressed |
28(a) |
1 → many |
2(34200999-34203985) |
ENSEMBL Gene Tree for CHP2 (if available)
TreeFam Gene Tree for CHP2 (if available) |
Paralogs
for CHP2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CHP2 gene
- CIB12 CIB32 PPP3R22 CIB42 PPP3R12 WDR922 TESC2 CIB22
- CHP12
6 SIMAP similar genes for CHP2 using alignment to 1 protein entry: CHP2_HUMAN:LOC63928 CHP1 HZGJ TESC PPP3R1 PPP3R2
CHP2 for paralogs About GeneDecksing
|
Genomic Variants
for CHP2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CHP2 (23765948 - 23770272 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CHP2: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHP2 |
|
Disorders
/ Diseases
for CHP2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CHP2 for disorders About GeneDecksing
8  diseases for CHP2: About MalaCardsamyotrophic lateral sclerosis (als) amyotrophic lateral sclerosis lateral sclerosis hepatocellular carcinoma
ovarian cancer tuberculosis carcinoma leukemia
Export disorders for CHP2 gene to outside databases
|
Publications
for CHP2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CHP2 gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with CHP2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Expression of calcineurin B homologous protein 2 protects serum deprivation-induced cell death by serum-independent activation of Na+/H+ exchanger. (PubMed id 12226101)1, 2, 3, 9 Pang T.... Shigekawa M. (2002)
- CHP2 activates the calcineurin/nuclear factor of activated T cells signaling pathway and enhances the oncogenic potential of HEK293 cells. (PubMed id 18815128)1, 2 Li G.D....Zhang Y. (2008)
- Crystal structure of CHP2 complexed with NHE1-cytosolic region and an implication for pH regulation. (PubMed id 16710297)1, 2 Ammar Y.B.... Wakabayashi S. (2006)
- Large scale identification of human hepatocellular carcinoma- associated antigens by autoantibodies. (PubMed id 12097419)1, 2 Wang Y....Chen W.-F. (2002)
- Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PubMed id 10493829)1, 2 Loftus B.J.... Adams M.D. (1999)
- Overexpression of CHP2 enhances tumor cell growth, invasion and metastasis in ovarian cancer. (PubMed id 17708351)1, 9 Jin Q....Yang Q. (2007)
- Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women. (PubMed id 21507922)1 Ramsuran V....Ndung'u T. (2011)
- Nuclear accumulation of calcineurin B homologous protein 2 (CHP2) results in enhanced proliferation of tumor cells. (PubMed id 21392185)2 Li Q.H....Pang T.X. (2011)
- [Expression of a tumor related gene chp2 in leukemia cells] (PubMed id 18718049)1 Li B....Pang T.X. (2008)
- Crystallization and preliminary crystallographic analysis of the human calcineurin homologous protein CHP2 bound to the cytoplasmic region of the Na+/H+ exchanger NHE1. (PubMed id 16511206)2 Ben Ammar Y....Wakabayashi S. (2005)
|
External Searches for CHP2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CHP2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CHP2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CHP2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for CHP2 gene:
Search GeneIP for patents involving CHP2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CHP2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CHP2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CHP2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHP2 | | | OriGene Protein Over-expression Lysate for CHP2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CHP2 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHP2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHP2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CHP2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHP2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHP2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CHP2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHP2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHP2 |
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