Aliases for CHORDC1 Gene
External Ids for CHORDC1 Gene
Previous GeneCards Identifiers for CHORDC1 Gene
GeneCards Summary for CHORDC1 Gene
CHORDC1 (Cysteine And Histidine-Rich Domain (CHORD) Containing 1) is a Protein Coding gene. Diseases associated with CHORDC1 include inclusion conjunctivitis. Among its related pathways are Alzheimers disease and Calcineurin-regulated NFAT-dependent transcription in lymphocytes. GO annotations related to this gene include Hsp90 protein binding. An important paralog of this gene is ITGB1BP2.
UniProtKB/Swiss-Prot for CHORDC1 Gene
Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis.