CHMP5 Gene
protein-coding GIFtS: 54
GCID: GC09P033257
|
|
charged multivesicular body protein 5(Previous names: chromosome 9 open reading frame 83, chromatin modifying...)
(Previous symbols: C9orf83, SNF7DC2)
| |
Aliases
for CHMP5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Charged Multivesicular Body Protein 51 2 | | HVps601 | | C9orf831 2 3 | | SNF7 Domain-Containing Protein 22 3 | | SNF7DC21 2 3 | | CGI-341 | | Vps601 2 3 | | Chromosome 9 Open Reading Frame 831 | | HSPC1771 2 | | PNAS-22 | | Chromatin Modifying Protein 51 2 | | Apoptosis-Related Protein PNAS-22 | | Chromatin-Modifying Protein 52 3 | | SNF7 Domain Containing 22 | | Vacuolar Protein Sorting-Associated Protein 602 3 | | |
Export aliases for CHMP5 gene to outside databases |
Summaries
for CHMP5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CHMP5:
CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins arecomponents of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation ofsurface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear andcytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation andregulation of cell cycle progression (Tsang et al., 2006 (PubMed 16730941)).(supplied by OMIM, Mar 2008)
UniProtKB/Swiss-Prot: CHMP5_HUMAN, Q9NZZ3Function: Probable peripherally associated component of the endosomal sorting required for transport complex III(ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins intoMVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limitingmembrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such asstimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequentialfunction of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membranebefore the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events,such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses).ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities,possibly in conjunction with the AAA ATPase VPS4. Involved in HIV-1 p6- and p9-dependent virus release
Gene Wiki entry for CHMP5
|
Genomic Views
for CHMP5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_008413.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CHMP5 gene promoter:
ER-alpha GR LHX3b/Lhx3b RFX1 Evi-1 POU2F1 POU2F1a LHX3a/Lhx3a GR-alpha ATF6
Other transcription factors
Search SABiosciences Chromatin IP Primers for CHMP5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHMP5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9p13.3 Ensembl cytogenetic band: 9p13.3 HGNC cytogenetic band: 9p13.3CHMP5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09P033257: view genomic region
(about GC identifiers)
Start:
|
33,264,877 bp from pter |
End:
|
33,281,977 bp from pter |
Size:
|
17,101 bases |
Orientation:
|
plus strand |
|
Proteins
for CHMP5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CHMP5_HUMAN, Q9NZZ3 (See
protein sequence)Recommended Name: Charged multivesicular body protein 5 Size: 219 amino acids; 24571 Da
Subunit: Probable peripherally associated component of the endosomal sorting required for transport complex III(ESCRT-III). ESCRT-III components are thought to multimerize to form a flat lattice on the perimeter membrane of theendosome. Several assembly forms of ESCRT-III may exist that interact and act sequentally. Interacts with VTA1.Interacts with CHMP2A. Interacts with VTA1; the interaction involves soluble CHMP5
Subcellular location: Cytoplasm, cytosol. Endosome membrane; Peripheral membrane protein (Probable). Note=Localizes tothe midbody of dividing cells. Localized in two distinct rings on either side of the Fleming body
Sequence caution: Sequence=AAG23821.1; Type=Erroneous initiation;
5 PDB 3D structures from  and Proteopedia  for CHMP5:2LXM (3D)
3ULY (3D)
3UM0 (3D)
3UM1 (3D)
3UM2 (3D)
Secondary accessions: B2RD95 B4DIR6 Q5VXW2 Q96AV2 Q9HB68 Q9NYS4 Q9Y323Alternative splicing: 2 isoforms: Q9NZZ3-1 Q9NZZ3-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for CHMP5: NX_Q9NZZ3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NZZ3
CHMP5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001182465.1 NP_057494.3
ENSEMBL proteins: ENSP00000223500 ENSP00000442725 Reactome Protein details: Q9NZZ3
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
CHMP5 for ontologies About GeneDecksing
CHMP5 Antibody Products:
Assay Products for CHMP5: |
Protein
Domains /
Families
for CHMP5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CHMP5 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9NZZ3ProtoNet protein and cluster: Q9NZZ3 1 Blocks protein family: IPB005024 Eukaryotic protein of unknown function DUF279
UniProtKB/Swiss-Prot: CHMP5_HUMAN, Q9NZZ3Similarity: Belongs to the SNF7 family |
Function
for CHMP5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CHMP5_HUMAN, Q9NZZ3Function: Probable peripherally associated component of the endosomal sorting required for transport complex III(ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins intoMVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limitingmembrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such asstimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequentialfunction of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membranebefore the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events,such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses).ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities,possibly in conjunction with the AAA ATPase VPS4. Involved in HIV-1 p6- and p9-dependent virus release
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHMP5 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHMP5 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector (see all 2): CHMP5 (NM_016410) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CHMP5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHMP5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHMP5 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
IPI | -- |
CHMP5 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Chmp5tm1Gho for CHMP5
6 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Chmp5):
CHMP5 for phenotypes About GeneDecksing
|
Pathways & Interactions
for CHMP5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Membrane Trafficking | | | 2 | Endocytosis | | | 3 | Signal Transduction | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for CHMP5
1 
Kegg Pathway (Kegg details for CHMP5):
CHMP5 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CHMP5
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/64 Interacting proteins for CHMP5 (Q9NZZ31, 2, 3 ENSP000002235004) via UniProtKB, MINT, STRING, and/or I2D (see all 64)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0001919 | regulation of receptor recycling |
IEA | -- | | GO:0007040 | lysosome organization |
IEA | -- | | GO:0008333 | endosome to lysosome transport |
IEA | -- | | GO:0015031 | protein transport |
IEA | -- | | GO:0016044 | cellular membrane organization |
TAS | -- |
CHMP5 for ontologies About GeneDecksing
|
Drugs & Compounds
for CHMP5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CHMP5
Search CenterWatch for drugs/clinical trials and news about CHMP5
|
Transcripts
for CHMP5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CHMP5 gene (2 alternative transcripts): NM_001195536.1 NM_016410.5 Unigene Cluster for CHMP5: Charged multivesicular body protein 5 Hs.635313 [show with all ESTs]Unigene Representative Sequence: NM_0164103 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000223500 ENST00000487080 ENST00000419016(uc003zsm.4 uc011lnv.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHMP5 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHMP5 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): CHMP5 (NM_016410) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CHMP5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHMP5 |
Additional cDNA sequence: AF132968.1 AF161525.1 AF229832.1 AF275810.1 AK024753.1 AK295744.1 AK315455.1 BC006974.1 BC007457.1 BC016698.1 BC018603.1 BC020796.1 BC021168.1 24 DOTS entries: DT.97859589 DT.70100200 DT.100701211 DT.100878174 DT.40111737 DT.121303570 DT.121156509 DT.100878172 DT.92331589 DT.70104660 DT.100878175 DT.92016989 DT.92439425 DT.100878176 DT.121156531 DT.91767476 DT.91970777 DT.95357916 DT.95372646 DT.95372647 DT.100691501 DT.100837530 DT.40132613 DT.97839334 24/574 AceView cDNA sequences (see all 574): AW614845 BP333968 BQ438350 AA470080 BC021168 BQ223761 BQ962070 BQ222522 CR601311 BC020796 AI279724 AI081009 BF103730 AW169778 BM479659 BM311551 CD107594 AI300288 BG170672 CB150763 CA842880 BQ722361 CR612296 AI911672
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for CHMP5 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b | ^ | 14a | · | 14b | ^ | 15 | ^ | 16 |
|---|
|
| SP1: | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CHMP5
|
Expression
for CHMP5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CHMP5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGTGGGTATT
About this image
See CHMP5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CHMP5
SOURCE GeneReport for Unigene cluster: Hs.635313
SABiosciences Custom PCR Arrays for CHMP5
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHMP5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CHMP5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHMP5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHMP5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHMP5 |
Orthologs
for CHMP5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CHMP5 gene from 8/33 species (see all 33) About this table
ENSEMBL Gene Tree for CHMP5 (if available)
TreeFam Gene Tree for CHMP5 (if available) |
Paralogs
for CHMP5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CHMP5 gene
CHMP5 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for CHMP5
PGOHUM00000244396 PGOHUM00000241268
|
Genomic Variants
for CHMP5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CHMP5 (33264877 - 33281977 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CHMP5: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHMP5 |
|
Disorders
/ Diseases
for CHMP5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CHMP5 for disorders About GeneDecksing
OMIM gene information: 610900
OMIM disorders: --
5  diseases for CHMP5: About MalaCardsconjunctivitis prostate cancer prostatitis malaria
leukemia
Human Genome Epidemiology (HuGE) Navigator: CHMP5 (1 document)
Export disorders for CHMP5 gene to outside databases
|
Publications
for CHMP5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CHMP5 gene, integrated from 9 sources (see all 34):
(articles sorted by number of sources associating them with CHMP5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The role of LIP5 and CHMP5 in multivesicular body formation and HIV-1 budding in mammalian cells. (PubMed id 15644320)1, 2, 3 Ward D.M.... Kaplan J. (2005)
- Targeting of AMSH to endosomes is required for epidermal growth factor receptor degradation. (PubMed id 17261583)1, 2 Ma Y.M.... Kirchhausen T. (2007)
- DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins. (PubMed id 14519844)1, 2 Martin-Serrano J.... Bieniasz P.D. (2003)
- CHMP1 functions as a member of a newly defined family of vesicle trafficking proteins. (PubMed id 11559748)1, 3 Howard T.L....Hollenberg S.M. (2001)
- Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (2000)
- Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2 Lai C.H....Lin W. (2000)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
|
External Searches for CHMP5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CHMP5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CHMP5 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CHMP5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CHMP5 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CHMP5 gene:
Search GeneIP for patents involving CHMP5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CHMP5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for CHMP5 | | OriGene shRNA RFP for CHMP5 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CHMP5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHMP5 | | | OriGene Protein Over-expression Lysate for CHMP5 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CHMP5 | | OriGene 3'-UTR Clone for CHMP5 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHMP5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHMP5 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CHMP5 | | OriGene Custom Protein Services for CHMP5 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CHMP5 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHMP5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHMP5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CHMP5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHMP5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHMP5 |
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| | | | Search Tocris compounds for CHMP5 |
| |  |  |  |  | | | | | | Recombinant Protein for CHMP5 |
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 | | | CHMP5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHMP5 |
|  |  |  | | | | ThermoFisher Antibody for CHMP5 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHMP5 |
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