CHMP2A Gene
protein-coding GIFtS: 59
GCID: GC19M059062
|
|
charged multivesicular body protein 2A(Previous name: chromatin modifying protein 2A )
| |
Aliases for CHMP2A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Charged Multivesicular Body Protein 2A1 2 | | Putative Breast Adenocarcinoma Marker BC-22 3 | | CHMP21 2 3 | | Vacuolar Protein Sorting-Associated Protein 2-12 3 | | VPS21 2 5 | | HVps2-11 | | VPS2A1 2 5 | | Putative Breast Adenocarcinoma Marker (32kD)2 | | BC22 3 5 | | VPS2 Homolog A2 | | BC-21 2 | | Vps2-13 | | Chromatin Modifying Protein 2A1 2 | | CHMP2a3 | | Chromatin-Modifying Protein 2a2 3 | | Vps2-13 |
Export aliases for CHMP2A gene to outside databasesPrevious GC identifers: GC19M063755 GC19M055373 |
Summaries for CHMP2A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for CHMP2A: CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins arecomponents of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation ofsurface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear andcytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation andregulation of cell cycle progression (Tsang et al., 2006 (PubMed 16730941)).(supplied by OMIM, Mar 2008) UniProtKB/Swiss-Prot: CHM2A_HUMAN, O43633Function: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which isinvolved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs containintraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of theendosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growthfactor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O,-I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV isreleased. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminalstages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins arebelieved to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction withthe AAA ATPase VPS4. Involved in HIV-1 p6- and p9-dependent virus release Gene Wiki entry for CHMP2A
|
Genomic Views for CHMP2A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the CHMP2A gene promoter: AML1a Other transcription factors
Search SABiosciences Chromatin IP Primers for CHMP2A
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHMP2A |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q Ensembl cytogenetic band: 19q13.43 HGNC cytogenetic band: 19q13.43CHMP2A Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M059062: view genomic region
(about GC identifiers)
Start:
|
59,062,933 bp from pter |
End:
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59,066,486 bp from pter |
Size:
|
3,554 bases |
Orientation:
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minus strand |
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Proteins for CHMP2A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: CHM2A_HUMAN, O43633 (See
protein sequence)Recommended Name: Charged multivesicular body protein 2a Size: 222 amino acids; 25104 Da
Subunit: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III). ESCRT-IIIcomponents are thought to multimerize to form a flat lattice on the perimeter membrane of the endosome. Severalassembly forms of ESCRT-III may exist that interact and act sequentally. In vitro, heteromerizes with CHMP3 (but notCHMP4) to form helical tubular structures that expose membrane-interacting sites on the outside whereas VPS4B canassociate on the inside of the tubule. Interacts with CHMP1B, CHMP2B, CHMP3, CHMP4A, CHMP4B, CHMP4C and CHMP5.Interacts with VPS4A; the interaction is direct. Interacts with VPS4B; the interaction is direct. Interacts withMITD1. Interacts with VTA1; the interaction probably involves the open conformation of CHMP2A
Subcellular location: Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to themidbody of dividing cells. Localized in two distinct rings on either side of the Fleming body
Miscellaneous: Its overexpression strongly inhibits HIV-1 release
Secondary accessions: B2R4W6 Q3ZTT0Explore the universe of human proteins at neXtProt for CHMP2A: NX_O43633
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O43633 CHMP2A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_055268.1 NP_940818.1 ENSEMBL proteins: ENSP00000310440 Reactome Protein details: O43633 Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005829 | cytosol |
TAS | -- | | GO:0031902 | late endosome membrane |
IEA | -- |
CHMP2A for ontologies About GeneDecksing
CHMP2A Antibody Products: Assay Products for CHMP2A: |
Protein
Domains / Families for CHMP2A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CHMP2A for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry O43633ProtoNet protein and cluster: O43633 1 Blocks protein family: IPB005024 Eukaryotic protein of unknown function DUF279
UniProtKB/Swiss-Prot: CHM2A_HUMAN, O43633Domain: The acidic C-terminus and the basic N-termminus are thought to render the protein in a closed, soluble andinactive conformation through an autoinhibitory intramolecular interaction. The open and active conformation, whichenables membrane binding and oligomerization, is achieved by interaction with other cellular binding partners,probably including other ESCRT componentsSimilarity: Belongs to the SNF7 family |
Function for CHMP2A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: CHM2A_HUMAN, O43633Function: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which isinvolved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs containintraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of theendosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growthfactor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O,-I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV isreleased. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminalstages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins arebelieved to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction withthe AAA ATPase VPS4. Involved in HIV-1 p6- and p9-dependent virus release
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHMP2A (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHMP2A (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): CHMP2A (NM_014453) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CHMP2A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHMP2A  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHMP2A |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
CHMP2A for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for CHMP2A:
|
Pathways & Interactions for CHMP2A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Membrane Trafficking | | | 2 | Endocytosis | | | 3 | Signal Transduction | |
Pathway sources See GeneCards unified pathways Show all pathways
2
Reactome Pathways for CHMP2A
1
Kegg Pathway (Kegg details for CHMP2A):
CHMP2A for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CHMP2A
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/61 Interacting proteins for CHMP2A (O436332, 3 ENSP000003104404) via UniProtKB, MINT, STRING, and/or I2D (see all 61)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0015031 | protein transport |
IEA | -- | | GO:0016044 | cellular membrane organization |
TAS | -- | | GO:0016197 | endosomal transport |
TAS | -- |
CHMP2A for ontologies About GeneDecksing
|
Drugs & Compounds for CHMP2A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for CHMP2A Search CenterWatch for drugs/clinical trials and news about CHMP2A / CHM2A 
|
Transcripts for CHMP2A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for CHMP2A gene (2 alternative transcripts): NM_014453.2 NM_198426.1 Unigene Cluster for CHMP2A: Charged multivesicular body protein 2A Hs.12107 [show with all ESTs]Unigene Representative Sequence: BM5424991 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000312547(uc002qti.3 uc002qtj.3 uc002qtk.3)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHMP2A (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHMP2A (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): CHMP2A (NM_014453) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CHMP2A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHMP2A  |
Additional cDNA sequence: AF042384.1 AK311974.1 AY364248.1 BC002502.2 BT007298.1 CR457002.1 15 DOTS entries: DT.115965 DT.121473517 DT.97845612 DT.121473599 DT.92442623 DT.121473534 DT.447840 DT.99997736 DT.121473615 DT.102840979 DT.86852138 DT.99953083 DT.100794836 DT.121473590 DT.121473538 24/286 AceView cDNA sequences (see all 286): NM_014453 BM705125 BC047005 CA389250 BU789464 BG170705 BQ712094 BF448087 AI868949 BM968237 BC002502 AI753410 AA287678 AW028829 BU789156 BU147101 BM853923 AI400758 CA420431 BU675029 BQ224738 BQ421018 BU844484 BU629792 GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for CHMP2A (see all 8) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | |
| SP1: | |   | |   | |   | - |   | - |   | - |   | - |   | |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | - |   | - |   | - |   | |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |   | |
| SP3: | |   | |   | |   | - |   | - |   | - |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | - |   | - |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for CHMP2A
|
Expression for CHMP2A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CHMP2A expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: GGTGATGAGG
About this image See CHMP2A Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for CHMP2A
SOURCE GeneReport for Unigene cluster: Hs.12107 SABiosciences Custom PCR Arrays for CHMP2A
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHMP2A Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CHMP2A | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHMP2A | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHMP2A | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHMP2A |
Orthologs for CHMP2A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CHMP2A gene from 10/37 species (see all 37) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
Chmp2a1 , 5 |
charged multivesicular body protein 2A1, 5 |
90.69(n)1 99.55(a)1 |
  |
7 (7.73 cM)5 689531 NM_026885.31 NP_081161.11 130320065 |
chicken (Gallus gallus) |
Aves |
CHMP2A6 |
-- |
87(a) |
1 ↔ 1 |
Un(2559030-2560512) |
lizard (Anolis carolinensis) |
Reptilia |
CHMP2A6 |
-- |
94(a) |
1 ↔ 1 |
GL343253.1(141846-146201) |
African clawed frog (Xenopus laevis) |
Amphibia |
CA788317.12 |
-- |
78.72(n) |
  |
CA788317.1 |
zebrafish (Danio rerio) |
Actinopterygii |
Dr.23612 |
Danio rerio mRNA similar to RIKEN cDNA 1500016L11 gene more |
77.55(n) |
  |
BC045320.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
vps21 |
CG14542-PA |
71.77(n) 75.23(a) |
  |
43164 NM_143198.1 NP_651455.1 |
worm (Caenorhabditis elegans) |
Secernentea |
vps-21 |
Protein VPS-2 |
65.02(n) 69.37(a) |
  |
174908 NM_064316.3 NP_496717.1 |
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes |
DID4(YKL002W)4 DID41 |
Class E Vps protein of the ESCRT-III complex, required more4 Did4p1 |
52.29(n)1 47.25(a)1 |
  |
11(437778-438544)4 8538681, 4 NP_012924.21, 4 |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
VPS2.11 |
vacuolar protein sorting-associated protein 2-1 |
60.43(n) 58.45(a) |
  |
815211 NM_126650.3 NP_565336.1 |
rice (Oryza sativa) |
Liliopsida |
AK071087.12 |
-- |
74.6(n) |
  |
AK071087.1 |
ENSEMBL Gene Tree for CHMP2A (if available) TreeFam Gene Tree for CHMP2A (if available)  |
Paralogs for CHMP2A gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for CHMP2A gene
- CHMP2B2
3 SIMAP similar genes for CHMP2A using alignment to 4 protein entries: CHM2A_HUMAN (see all proteins):CHMP2B CHMP1B CHMP3
CHMP2A for paralogs About GeneDecksing
|
Genomic Variants for CHMP2A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 19 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for CHMP2A (59062933 - 59066486 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 4 variations for CHMP2A 3 CNVs: 50240 50238 50239 1 Indel: 58896  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHMP2A |
|
Disorders
/ Diseases for CHMP2A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CHMP2A for disorders About GeneDecksing
OMIM gene information: 610893
OMIM disorders: --
3 diseases for CHMP2A: About MalaCardsbreast adenocarcinoma adenocarcinoma conjunctivitis Export disorders for CHMP2A gene to outside databases
|
Publications for CHMP2A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CHMP2A gene, integrated from 9 sources (see all 36): (articles sorted by number of sources associating them with CHMP2A) | |  | Utopia: connect your pdf to the dynamic world of online information |
- CHMP1 functions as a member of a newly defined family of vesicle trafficking proteins. (PubMed id 11559748)1, 2, 3 Howard T.L....Hollenberg S.M. (2001)
- Helical structures of ESCRT-III are disassembled by VPS4. (PubMed id 18687924)1, 2, 9 Lata S....Weissenhorn W. (2008)
- A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex. (PubMed id 16730941)1, 2 Tsang H.T.H....Sanderson C.M. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Mammalian class E Vps proteins, SBP1 and mVps2/CHMP2A, interact with and regulate the function of an AAA-ATPase SKD1/Vps4B. (PubMed id 15173323)1, 3 Fujita H....Himeno M. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The protein network of HIV budding. (PubMed id 14505570)1, 2 von Schwedler U.K.... Sundquist W.I. (2003)
- Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (2003)
- Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins. (PubMed id 14519844)1, 2 Martin-Serrano J.... Bieniasz P.D. (2003)
- Novel interactions of ESCRT-III with LIP5 and VPS4 and their implications for ESCRT-III disassembly. (PubMed id 18385515)2, 9 Shim S.... Hanson P.I. (2008)
|
External Searches for CHMP2A gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing CHMP2A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CHMP2A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CHMP2A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
|
About This Section
| Patent Information for CHMP2A gene: Search GeneIP for patents involving CHMP2A
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products for CHMP2A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
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| | | | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CHMP2A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHMP2A | | OriGene Protein Over-expression Lysate for CHMP2A | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for CHMP2A | | OriGene 3'-UTR Clone for CHMP2A | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHMP2A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHMP2A | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for CHMP2A | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for CHMP2A | | OriGene Custom Protein Services for CHMP2A | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CHMP2A | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHMP2A | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHMP2A | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CHMP2A | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHMP2A | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHMP2A |
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| | | Search Tocris compounds for CHMP2A |
| |  |  |  |  | | | | | Recombinant Protein for CHMP2A |
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 | | CHMP2A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHMP2A |
|  |  |  | | | Search ThermoFisher Antibodies for CHMP2A |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHMP2A |
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