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CHMP1B Gene

protein-coding   GIFtS: 53
GCID: GC18P011851

Charged Multivesicular Body Protein 1B

(Previous name: chromatin modifying protein 1B)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Charged Multivesicular Body Protein 1B1 2     hVps46-22 3
Chromatin Modifying Protein 1B1 2     C10orf22 5
Chromatin-Modifying Protein 1b2 3     C18-ORF22
Vacuolar Protein Sorting-Associated Protein 46-22 3     Vps46B2
C18orf22 3     Vacuolar Protein Sorting 46-22
CHMP1.52 3     CHMP1b3
Vps46-22 3     

External Ids:    HGNC: 242871   Entrez Gene: 571322   Ensembl: ENSG000002551127   OMIM: 6064865   UniProtKB: Q7LBR13   

Export aliases for CHMP1B gene to outside databases

Previous GC identifer: GC18P011842


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CHMP1B Gene:
CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These
proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved
in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs
have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required
for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 (PubMed 16730941)).(supplied
by OMIM, Mar 2008)

GeneCards Summary for CHMP1B Gene:
CHMP1B (charged multivesicular body protein 1B) is a protein-coding gene. Diseases associated with CHMP1B include hereditary spastic paraplegia, and paraplegia. GO annotations related to this gene include protein domain specific binding. An important paralog of this gene is CHMP1A.

UniProtKB/Swiss-Prot: CHM1B_HUMAN, Q7LBR1
Function: Probable peripherally associated component of the endosomal sorting required for transport complex III
(ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins
into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the
limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane
proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to
require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from
the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically
equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped
viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle
extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in
cytokinesis. Involved in recruiting VPS4A and/or VPS4B and SPAST to the midbody of dividing cells. Involved in
HIV-1 p6- and p9-dependent virus release

Gene Wiki entry for CHMP1B Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000018.10  NC_018929.2  NT_010859.15  
Regulatory elements:
   Regulatory transcription factor binding sites in the CHMP1B gene promoter:
         SRF   NF-1   NF-1/L   Pax-5   AML1a   ATF-2   SRF (504 AA)   c-Ets-1   NRF-2   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCHMP1B promoter sequence
   Search Chromatin IP Primers for CHMP1B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CHMP1B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18p11.21   Ensembl cytogenetic band:  18p11.21   HGNC cytogenetic band: 18p11.21

CHMP1B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CHMP1B gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18P011851:  view genomic region     (about GC identifiers)

Start:
11,851,389 bp from pter      End:
11,854,448 bp from pter
Size:
3,060 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: CHM1B_HUMAN, Q7LBR1 (See protein sequence)
Recommended Name: Charged multivesicular body protein 1b  
Size: 199 amino acids; 22109 Da
Subunit: Probable peripherally associated component of the endosomal sorting required for transport complex III
(ESCRT-III). ESCRT-III components are thought to multimerize to form a flat lattice on the perimeter membrane of
the endosome. Several assembly forms of ESCRT-III may exist that interact and act sequentally. Interacts with
CHMP1A. Interacts with VTA1; the interaction probably involves the open conformation of CHMP1B. Interacts with
CHMP2A. Interacts with VPS4A; the interaction is direct. Interacts with VPS4B; the interaction is direct.
Interacts with SPAST (via MIT domain); the interaction is direct. Interacts with IST1. Interacts with MITD1.
Interacts with STAMBP
Sequence caution: Sequence=AAG01449.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for CHMP1B:
3EAB (3D)    
Secondary accessions: Q96E89 Q9HD41

Explore the universe of human proteins at neXtProt for CHMP1B: NX_Q7LBR1

Explore proteomics data for CHMP1B at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys6, Lys12, Lys42, Lys87, Lys104, Lys110
  • Modification sites at PhosphoSitePlus

  • See CHMP1B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_065145.2  
    ENSEMBL proteins: 
     ENSP00000432279  

    CHMP1B Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    CHMP: Charged multivesicular body proteins

    1 InterPro protein domain:
     IPR005024 Snf7

    Graphical View of Domain Structure for InterPro Entry Q7LBR1

    ProtoNet protein and cluster: Q7LBR1

    1 Blocks protein domain: IPB005024 Eukaryotic protein of unknown function DUF279

    UniProtKB/Swiss-Prot: CHM1B_HUMAN, Q7LBR1
    Similarity: Belongs to the SNF7 family


    CHMP1B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CHM1B_HUMAN, Q7LBR1
    Function: Probable peripherally associated component of the endosomal sorting required for transport complex III
    (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins
    into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the
    limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane
    proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to
    require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from
    the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically
    equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped
    viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle
    extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in
    cytokinesis. Involved in recruiting VPS4A and/or VPS4B and SPAST to the midbody of dividing cells. Involved in
    HIV-1 p6- and p9-dependent virus release

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI17711858
    GO:0019904protein domain specific binding IPI17928862
         
    CHMP1B for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CHMP1B
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    Block miRNA regulation of human, mouse, rat CHMP1B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CHMP1B (see all 35):
    hsa-miR-300 hsa-miR-3653 hsa-miR-502-3p hsa-miR-9 hsa-miR-3658 hsa-miR-181b hsa-miR-3163 hsa-miR-381
    SwitchGear 3'UTR luciferase reporter plasmidCHMP1B 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CHM1B_HUMAN, Q7LBR1: Cytoplasm, cytosol. Endosome. Late endosome membrane; Peripheral membrane protein
    (Probable). Note=Localizes to the midbody of dividing cells, colocalizing with CEP55 and CHMP5. Localized at the
    periphery of the Fleming body

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol IEA--
    GO:0031902late endosome membrane IEA--
    GO:0070062extracellular vesicular exosome IDA19056867

    CHMP1B for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for CHMP1B About    
    See pathways by source

    SuperPathContained pathways About
    1Endocytosis
    Endocytosis

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways




    1 Kegg Pathway  (Kegg details for CHMP1B):
        Endocytosis


    CHMP1B for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CHMP1B
    Interactions:

        GeneGlobe Interaction Network for CHMP1B

    Selected Interacting proteins for CHMP1B (Q7LBR11, 2, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 25)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    USP8P408181, 2, 3EBI-2118090,EBI-1050865 MINT-6946799 I2D: score=3 
    STAMBPO956301, 3EBI-2118090,EBI-396676 I2D: score=3 
    USP54Q70EL12, 3MINT-6947265 I2D: score=1 
    VPS4AQ9UN373I2D: score=2 
    VPS4BO753513I2D: score=2 
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000910cytokinesis IMP19129479
    GO:0015031protein transport IEA--
    GO:0045184establishment of protein localization IMP--

    CHMP1B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CHMP1B (CHM1B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for CHMP1B gene: 
    NM_020412.4  

    Unigene Cluster for CHMP1B:

    Charged multivesicular body protein 1B
    Hs.656244  [show with all ESTs]
    Unigene Representative Sequence: NM_020412
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000526991(uc002kqe.3) ENST00000588284
    miRNA
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    hsa-miR-300 hsa-miR-3653 hsa-miR-502-3p hsa-miR-9 hsa-miR-3658 hsa-miR-181b hsa-miR-3163 hsa-miR-381
    SwitchGear 3'UTR luciferase reporter plasmidCHMP1B 3' UTR sequence
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      QuantiFast Probe-based Assays in human, mouse, rat CHMP1B

    Additional mRNA sequence: 

    AF281064.1 AJ227887.1 AK314068.1 BC012733.2 BC065933.1 

    12 DOTS entries:

    DT.456010  DT.100807602  DT.100710406  DT.95100288  DT.121097667  DT.95339044  DT.97823223  DT.100807591 
    DT.102842686  DT.121097637  DT.75163694  DT.95149101 

    Selected AceView cDNA sequences (see all 217):

    CA398228 CR616002 CB130551 NM_020412 CR595824 BM820146 AW022811 AA399458 
    AA830305 BU161149 CB070114 AI564294 CR600805 BU627541 AL546791 BC065933 
    CD369914 BQ218135 CF131956 BE877631 CR609924 BU683605 BM839878 AF281064 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CHMP1B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGTGTATTC
    CHMP1B Expression
    About this image

    CHMP1B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CHMP1B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.656244

    UniProtKB/Swiss-Prot: CHM1B_HUMAN, Q7LBR1
    Tissue specificity: Widely expressed. Expressed in pancreas, kidney, skeletal muscle, liver, lung, placenta and
    brain

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for CHMP1B gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Chmp1b1 , 5 charged multivesicular body protein 1B1, 5 92.29(n)1
    97.99(a)1
      18 (39.89 cM)5
    670641  NM_024190.21  NP_077152.11 
     672053595 
    chicken
    (Gallus gallus)
    Aves CHMP1B6
    Gallus gallus charged multivesicular body protein ...
    96(a)
    1 ↔ 1
    4(1501100-1507668)
    lizard
    (Anolis carolinensis)
    Reptilia CHMP1B6
    charged multivesicular body protein 1B
    93(a)
    1 ↔ 1
    GL343528.1(17852-21612)
    fruit fly
    (Drosophila melanogaster)
    Insecta Chmp16
    Chmp1
    73(a)
    1 ↔ 1
    3L(18676244-18677161)
    worm
    (Caenorhabditis elegans)
    Secernentea did-26
    Protein F23C8.6 (F23C8.6) mRNA, complete cds
    54(a)
    1 ↔ 1
    I(2420831-2421742) WBGene00017735
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes DID26
    Class E protein of the vacuolar protein-sorting (V...
    40(a)
    1 → many
    XI(507939-508553) YKR035W-A


    ENSEMBL Gene Tree for CHMP1B (if available)
    TreeFam Gene Tree for CHMP1B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CHMP1B gene
    CHMP1A2  
    2 SIMAP similar genes for CHMP1B using alignment to 1 protein entry:     CHM1B_HUMAN:
    CHMP1A    CHMP2A

    CHMP1B for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for CHMP1B
    PGOHUM00000258429


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for CHMP1B:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv833590CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing CHMP1B
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606486    OMIM disorders: --

    6 diseases for CHMP1B:    
    About MalaCards
    hereditary spastic paraplegia    paraplegia    conjunctivitis    bipolar disorder
    spasticity    hiv-1


    CHMP1B for disorders           About GeneDecksing

    Genetic Association Database (GAD): CHMP1B
    Human Genome Epidemiology (HuGE) Navigator: CHMP1B (2 documents)

    Export disorders for CHMP1B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CHMP1B gene, integrated from 10 sources (see all 43):
    (articles sorted by number of sources associating them with CHMP1B)
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    1. The hereditary spastic paraplegia protein spastin interacts with the ESCRT-III complex-associated endosomal protein CHMP1B. (PubMed id 15537668)1, 2, 3 Reid E....Sanderson C.M. (Hum. Mol. Genet. 2005)
    2. Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B. (PubMed id 18997780)1, 2, 9 Yang D.... Hurley J.H. (Nat. Struct. Mol. Biol. 2008)
    3. Structure and ESCRT-III protein interactions of the MIT domain of human VPS4A. (PubMed id 16174732)1, 2, 9 Scott A....Sundquist W.I. (Proc. Natl. Acad. Sci. U.S.A. 2005)
    4. Essential role of hIST1 in cytokinesis. (PubMed id 19129480)1, 2 Agromayor M.... Martin-Serrano J. (Mol. Biol. Cell 2009)
    5. Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population. (PubMed id 19328558)1, 4 Yosifova A....Nakamura Y. (J Affect Disord 2009)
    6. Biochemical analyses of human IST1 and its function in cytokinesis. (PubMed id 19129479)1, 2 Bajorek M....Sundquist W.I. (Mol. Biol. Cell 2009)
    7. ESCRT-III recognition by VPS4 ATPases. (PubMed id 17928862)1, 2 Stuchell-Brereton M.D.... Sundquist W.I. (Nature 2007)
    8. A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex. (PubMed id 16730941)1, 2 Tsang H.T.H....Sanderson C.M. (Genomics 2006)
    9. Association analysis of CHMP1.5 genetic variation and bipolar disorder. (PubMed id 16094257)1, 4 McNabb L.D....Berrettini W.H. (Psychiatr. Genet. 2005)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57132 HGNC: 24287 AceView: CHMP1.5 Ensembl:ENSG00000255112 euGenes: HUgn57132
    ECgene: CHMP1B Kegg: 57132 H-InvDB: CHMP1B

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CHMP1B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CHMP1B gene:
    Search GeneIP for patents involving CHMP1B

    GeneCards and IP:
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