CHMP1A Gene
protein-coding GIFtS: 53
GCID: GC16M089710
|
|
charged multivesicular body protein 1A(Previous names: procollagen (type III) N-endopeptidase, chromatin modifying...)
(Previous symbols: PRSM1, PCOLN3)
| |
Aliases
for CHMP1A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Charged Multivesicular Body Protein 1A1 2 | | PCH82 | | PCOLN31 2 3 5 | | VPS46-12 | | PRSM11 2 3 5 | | VPS46A2 | | CHMP11 2 3 | | Charged Multivesicular Body Protein 1/Chromatin Modifying Protein 12 | | Chromatin Modifying Protein 1A1 2 | | Protease, Metallo, 1, 33kD2 | | Procollagen (Type III) N-Endopeptidase1 2 | | CHMP1a3 | | KIAA00471 3 | | Vps46-13 | | Vacuolar Protein Sorting-Associated Protein 46-12 3 | | Chromatin-Modifying Protein 1a3 | | Vps46A1 | | HVps46-11 |
Export aliases for CHMP1A gene to outside databasesPrevious GC identifers: GC16M088239 GC16M075406 |
Summaries
for CHMP1A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CHMP1A:
This gene encodes a member of the CHMP/Chmp family of proteins which are involved in multivesicular body sorting ofproteins to the interiors of lysosomes. The initial prediction of the protein sequence encoded by this gene suggestedthat the encoded protein was a metallopeptidase. The nomenclature has been updated recently to reflect the correctbiological function of this encoded protein. Several transcripts encoding different isoforms have been found for thisgene. (provided by RefSeq, Dec 2012)
UniProtKB/Swiss-Prot: CHM1A_HUMAN, Q9HD42Function: Probable peripherally associated component of the endosomal sorting required for transport complex III(ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins intoMVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limitingmembrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such asstimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequentialfunction of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membranebefore the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events,such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses).ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities,possibly in conjunction with the AAA ATPase VPS4. Involved in cytokinesis. Involved in recruiting VPS4A and/or VPS4Bto the midbody of dividing cells. May also be involved in chromosome condensation. Targets the Polycomb group (PcG)protein BMI1/PCGF4 to regions of condensed chromatin. May play a role in stable cell cycle progression and in PcG genesilencing
Gene Wiki entry for CHMP1A
|
Genomic Views
for CHMP1A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010542.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CHMP1A gene promoter:
SREBP-1c MyoD AP-2gamma Meis-1b Arnt SREBP-1b HNF-4alpha1 E2F E2F-1 SREBP-1a
Other transcription factors
Search SABiosciences Chromatin IP Primers for CHMP1A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHMP1A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q24.3 Ensembl cytogenetic band: 16q24.3 HGNC cytogenetic band: 16q24.3CHMP1A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M089710: view genomic region
(about GC identifiers)
Start:
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89,710,839 bp from pter |
End:
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89,724,253 bp from pter |
Size:
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13,415 bases |
Orientation:
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minus strand |
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Proteins
for CHMP1A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CHM1A_HUMAN, Q9HD42 (See
protein sequence)Recommended Name: Charged multivesicular body protein 1a Size: 196 amino acids; 21703 Da
Subunit: Probable peripherally associated component of the endosomal sorting required for transport complex III(ESCRT-III). ESCRT-III components are thought to multimerize to form a flat lattice on the perimeter membrane of theendosome. Several assembly forms of ESCRT-III may exist that interact and act sequentally. Self-associates. Interactswith CHMP1B. Interacts with VPS4A. Interacts with VPS4B. Interacts with PHF1. Interacts with IST1. Interacts withMITD1
Subcellular location: Cytoplasm. Endosome membrane; Peripheral membrane protein. Nucleus matrix. Note=The cytoplasmicform is partially membrane-associated and localizes to early endosomes. The nuclear form remains associated with thechromosome scaffold during mitosis. On overexpression, it localizes to nuclear bodies characterized bynuclease-resistant condensed chromatin
Caution: Was originally (PubMed:8863740) thought to be a metalloprotease (PRSM1). This was based on a wrong translationof the ORF which gave rise to a putative protein of 318 AA containing a pattern reminiscent of zinc metalloproteases
Sequence caution: Sequence=AAC50775.1; Type=Erroneous translation; Note=Wrong choice of frame; Sequence=BAA07557.1;Type=Erroneous translation; Note=Wrong choice of frame;
3 PDB 3D structures from  and Proteopedia  for CHMP1A:2JQ9 (3D)
2YMB (3D)
4A5X (3D)
Secondary accessions: A2RU09 Q14468 Q15779 Q96G31Alternative splicing: 2 isoforms: Q9HD42-1 Q9HD42-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for CHMP1A: NX_Q9HD42
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9HD42
CHMP1A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001076783.1 NP_002759.2
ENSEMBL proteins: ENSP00000380998 ENSP00000442120 ENSP00000449243 ENSP00000447899 ENSP00000253475
Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
CHMP1A for ontologies About GeneDecksing
CHMP1A Antibody Products:
Assay Products for CHMP1A: |
Protein
Domains /
Families
for CHMP1A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CHMP1A for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9HD42ProtoNet protein and cluster: Q9HD42 1 Blocks protein family: IPB005024 Eukaryotic protein of unknown function DUF279
UniProtKB/Swiss-Prot: CHM1A_HUMAN, Q9HD42Similarity: Belongs to the SNF7 family |
Function
for CHMP1A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CHM1A_HUMAN, Q9HD42Function: Probable peripherally associated component of the endosomal sorting required for transport complex III(ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins intoMVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limitingmembrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such asstimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequentialfunction of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membranebefore the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events,such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses).ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities,possibly in conjunction with the AAA ATPase VPS4. Involved in cytokinesis. Involved in recruiting VPS4A and/or VPS4Bto the midbody of dividing cells. May also be involved in chromosome condensation. Targets the Polycomb group (PcG)protein BMI1/PCGF4 to regions of condensed chromatin. May play a role in stable cell cycle progression and in PcG genesilencingInduction: By muristerone
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHMP1A (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHMP1A (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHMP1A |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
CHMP1A for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for CHMP1A:
|
Pathways & Interactions
for CHMP1A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CHMP1A
STRING Interaction
Network Preview (showing 5 interactants - click image to see 10)
5/23 Interacting proteins for CHMP1A (Q9HD421, 2, 3 ENSP000002534754) via UniProtKB, MINT, STRING, and/or I2D (see all 23)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| USP8 | P408181, 2, 3, ENSP000003022394 | EBI-1057156,EBI-1050865 MINT-6946783 I2D:
score=3 STRING: ENSP00000302239 | | STAMBP | O956301, 3, ENSP000003447424 | EBI-1057156,EBI-396676 I2D:
score=2 STRING: ENSP00000344742 | | USP54 | Q70EL12, 3, ENSP000003452164 | MINT-6946930 I2D:
score=1 STRING: ENSP00000345216 | | KIAA1715 | Q9C0E83, ENSP000002727484 | I2D:
score=2 STRING: ENSP00000272748 | | VPS4A | Q9UN373, ENSP000002549504 | I2D:
score=2 STRING: ENSP00000254950 |
About this table
Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10): About this table
CHMP1A for ontologies About GeneDecksing
|
Drugs & Compounds
for CHMP1A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CHMP1A
Search CenterWatch for drugs/clinical trials and news about CHMP1A / CHM1A
|
Transcripts
for CHMP1A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CHMP1A gene (2 alternative transcripts): NM_001083314.3 NM_002768.4 Unigene Cluster for CHMP1A: Charged multivesicular body protein 1A Hs.589427 [show with all ESTs]Unigene Representative Sequence: NR_04641811 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000397901(uc002fnu.3 uc002fnv.3) ENST00000547687(uc002fnt.3)
ENST00000535997 ENST00000549139 ENST00000550102 ENST00000549328 ENST00000551981
ENST00000548650 ENST00000547614 ENST00000550872 ENST00000253475
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHMP1A (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHMP1A (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): CHMP1A (NM_002768) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CHMP1A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHMP1A |
Additional cDNA sequence: AF281063.1 AK302055.1 BC007527.1 BC010000.2 BC132711.1 BC132713.1 BT006841.1 D38554.1 NR_046418.2 U58048.1 19 DOTS entries: DT.446956 DT.100886073 DT.100886047 DT.97859944 DT.99983922 DT.91754015 DT.95159578 DT.100886070 DT.102833352 DT.100886049 DT.100886058 DT.100886065 DT.120728264 DT.120728265 DT.120728291 DT.75197121 DT.95100760 DT.95320001 DT.75126166 24/380 AceView cDNA sequences (see all 380): BQ723635 BU731045 CD366308 CR618565 BX366185 BG480548 BX443722 BF037744 BM820370 AI193119 BE514420 BU167140 BM763906 CR620879 AW078609 BP365411 BP342283 BM818966 AI355397 AA669311 BC007527 BQ691227 BU944725 AW327795
GeneLoc Exon Structure
|
Expression
for CHMP1A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CHMP1A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGCCAGGTGG
About this image
See CHMP1A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CHMP1A
SOURCE GeneReport for Unigene cluster: Hs.589427
UniProtKB/Swiss-Prot: CHM1A_HUMAN, Q9HD42Tissue specificity: Expressed in placenta, cultured skin fibroblasts and in osteoblast cell line MG-63
SABiosciences Custom PCR Arrays for CHMP1A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHMP1A
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CHMP1A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHMP1A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHMP1A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHMP1A |
Orthologs
for CHMP1A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CHMP1A gene from 7/33 species (see all 33) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
CHMP1A1 |
chromatin modifying protein 1A |
85.2(n)
94.9(a) |
|
415841 NM_001025440.1 NP_001020611.1 |
lizard
(Anolis carolinensis) |
Reptilia |
CHMP1A6 |
-- |
87(a) |
1 ↔ 1 |
GL343487.1(602460-606605) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.255842 |
Xenopus laevis transcribed sequence with weak similarity more |
79.63(n) |
|
CA793301.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc659142 |
hypothetical protein MGC65914 |
83.54(n) |
|
393535 AY398372.1 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
DID21 |
Did2p |
53.2(n)
48.19(a) |
|
853906 NP_012961.3 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
VPS46.26VPS46.16 |
vacuolar protein sorting 46.1 |
43(a)41(a) |
many ↔ manymany ↔ many |
1(27473826-27475122) 1(6099089-6100315) |
rice
(Oryza sativa) |
Liliopsida |
-- |
SNF7 domain containing protein, putative, expresse... |
43(a) |
1 → many |
6(26214485-26217669) |
ENSEMBL Gene Tree for CHMP1A (if available)
TreeFam Gene Tree for CHMP1A (if available) |
Paralogs
for CHMP1A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CHMP1A gene
- CHMP1B2
2 SIMAP similar genes for CHMP1A using alignment to 5 protein entries: CHM1A_HUMAN (see all proteins):PCOLN3 CHMP1B
CHMP1A for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for CHMP1A
PGOHUM00000243947
|
Genomic Variants
for CHMP1A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CHMP1A (89710839 - 89724253 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for CHMP1A
2 Indels: 11853 72701
Human Gene Mutation Database (HGMD): CHMP1A
| SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for CHMP1A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CHMP1A for disorders About GeneDecksing
OMIM gene information: 164010
OMIM disorders: --
7  diseases for CHMP1A: About MalaCardsataxia telangiectasia lymphedema hepatitis c conjunctivitis
ataxia hepatitis pancreatitis
Export disorders for CHMP1A gene to outside databases
|
Publications
for CHMP1A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CHMP1A gene, integrated from 9 sources (see all 35):
(articles sorted by number of sources associating them with CHMP1A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- CHMP1 is a novel nuclear matrix protein affecting chromatin structure and cell-cycle progression. (PubMed id 11559747)1, 2, 3, 9 Stauffer D.R....Hollenberg S.M. (2001)
- CHMP1 functions as a member of a newly defined family of vesicle trafficking proteins. (PubMed id 11559748)1, 2, 3 Howard T.L....Hollenberg S.M. (2001)
- Biochemical analyses of human IST1 and its function in cytokinesis. (PubMed id 19129479)1, 2, 9 Bajorek M....Sundquist W.I. (2009)
- Molecular cloning, expression and chromosomal localization of a human gene encoding a 33 kDa putative metallopeptidase (PRSM1). (PubMed id 8863740)1, 2, 9 Scott I.C.... Kadler K.E. (1996)
- ESCRT-III recognition by VPS4 ATPases. (PubMed id 17928862)1, 2 Stuchell-Brereton M.D.... Sundquist W.I. (2007)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The protein network of HIV budding. (PubMed id 14505570)1, 2 von Schwedler U.K.... Sundquist W.I. (2003)
- Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins. (PubMed id 14519844)1, 2 Martin-Serrano J.... Bieniasz P.D. (2003)
- Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 7584044)1, 2 Nomura N....Tabata S. (1994)
- Chmp1A functions as a novel tumor suppressor gene in human embryonic kidney and ductal pancreatic tumor cells. (PubMed id 18787405)1, 9 Li J....Park M. (2008)
|
External Searches for CHMP1A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CHMP1A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CHMP1A gene
(According to HUGE)
About This Section
| |
Specialized Databases showing CHMP1A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CHMP1A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CHMP1A gene:
Search GeneIP for patents involving CHMP1A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for CHMP1A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CHMP1A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CHMP1A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHMP1A | | | OriGene Protein Over-expression Lysate for CHMP1A | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CHMP1A | | OriGene 3'-UTR Clone for CHMP1A | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHMP1A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHMP1A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CHMP1A | | OriGene Custom Protein Services for CHMP1A | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CHMP1A | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHMP1A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHMP1A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CHMP1A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHMP1A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHMP1A |
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| | | | Search Tocris compounds for CHMP1A |
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 | | | CHMP1A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHMP1A |
|  |  |  | | | | ThermoFisher Antibodies for CHMP1A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHMP1A |
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