CHML Gene
protein-coding GIFtS: 51
GCID: GC01M241792
|
|
choroideremia-like (Rab escort protein 2)
| |
Aliases
for CHML gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Choroideremia-Like (Rab Escort Protein 2)1 2 | | Rab Proteins Geranylgeranyltransferase Component A 22 | | REP22 3 5 | | Choroideremia-Like Protein3 | | REP-21 3 | | Rab Escort Protein 23 | | Choroideraemia-Like Protein2 | | |
Export aliases for CHML gene to outside databasesPrevious GC identifers: GC01M239882 GC01M237250 GC01M238093 GC01M238838 GC01M238122 GC01M239858 GC01M212250 |
Summaries
for CHML gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CHML:
The product of the CHML gene supports geranylgeranylation of most Rab proteins and may substitute for REP-1 in tissuesother than retina. CHML is localized close to the gene for Usher syndrome type II. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: RAE2_HUMAN, P26374Function: Binds unprenylated Rab proteins, presents it to the catalytic Rab GGTase dimer, and remains bound to it afterthe geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rabback to the donor membrane. Less effective than REP-1 in supporting prenylation of Rab3 family
Gene Wiki entry for CHML
|
Genomic Views
for CHML gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_167186.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CHML gene promoter:
AML1a POU3F1 CUTL1 C/EBPalpha NF-AT E47 NF-AT4 NF-AT2 NF-AT3 NF-AT1
Other transcription factors
Search SABiosciences Chromatin IP Primers for CHML
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHML |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q42-qter Ensembl cytogenetic band: 1q43 HGNC cytogenetic band: 1q42-qterCHML Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M241792: view genomic region
(about GC identifiers)
Start:
|
241,792,155 bp from pter |
End:
|
241,799,232 bp from pter |
Size:
|
7,078 bases |
Orientation:
|
minus strand |
|
Proteins
for CHML gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RAE2_HUMAN, P26374 (See
protein sequence)Recommended Name: Rab proteins geranylgeranyltransferase component A 2 Size: 656 amino acids; 74071 Da
Subunit: Monomer. Interacts with Rab and Rab GGTase
Miscellaneous: Substitutes for REP-1 thereby preventing widespread tissue abnormalities in patients with choroideremiawho lack REP-1
Secondary accessions: B2RAB9 Q17RE0 Q9H1Y4Explore the universe of human proteins at neXtProt for CHML: NX_P26374
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P26374
CHML Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001812.2
ENSEMBL proteins: ENSP00000355511
Human Recombinant Protein Products for CHML:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005968 | Rab-protein geranylgeranyltransferase complex |
IEA | -- |
CHML for ontologies About GeneDecksing
CHML Antibody Products:
Assay Products for CHML: |
Protein
Domains /
Families
for CHML gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CHML for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P26374ProtoNet protein and cluster: P26374 1 Blocks protein family: IPB001738 Rab escort (choroideraemia) protein signature
UniProtKB/Swiss-Prot: RAE2_HUMAN, P26374Similarity: Belongs to the Rab GDI family |
Function
for CHML gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: RAE2_HUMAN, P26374Function: Binds unprenylated Rab proteins, presents it to the catalytic Rab GGTase dimer, and remains bound to it afterthe geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rabback to the donor membrane. Less effective than REP-1 in supporting prenylation of Rab3 family Genatlas biochemistry entry for CHML:Rab escort protein-2 activating geranylgeranyltransferase A (prenylating C terminus of RAB (signal transduction)
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004663 | Rab geranylgeranyltransferase activity |
IEA | -- | | GO:0005096 | GTPase activator activity |
IEA | -- |
CHML for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for CHML:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHML (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHML
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector: CHML (NM_001821) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CHML | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHML |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHML |
|
Pathways & Interactions
for CHML gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CHML
STRING Interaction
Network Preview (showing 5 interactants - click image to see 7)
5/7 Interacting proteins for CHML (P263743 ENSP000003555114) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
CHML for ontologies About GeneDecksing
|
Drugs & Compounds
for CHML gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CHML
Search CenterWatch for drugs/clinical trials and news about CHML / RAE2
|
Transcripts
for CHML gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CHML gene: NM_001821.3 Unigene Cluster for CHML: Choroideremia-like (Rab escort protein 2) Hs.654545 [show with all ESTs]Unigene Representative Sequence: NM_0018211 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000366553(uc001hzd.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHML (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHML
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CHML (NM_001821) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CHML | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHML |
Additional cDNA sequence: AJ293390.1 AJ293391.1 AJ293392.1 AK000933.1 AK023423.1 AK314125.1 BC117360.1 X64728.1 3 DOTS entries: DT.102994 DT.100041830 DT.100743529 24/100 AceView cDNA sequences (see all 100): BQ437051 CA312626 BU509892 BE348356 AA804486 BE503084 BI088411 BM763291 AI829541 BE468155 AI741219 BE895865 BF437331 BM557064 CB160778 BX956583 T11394 AI373290 AI004823 AI167858 BQ775652 NM_001821 AK023423 BF217939
GeneLoc Exon Structure
|
Expression
for CHML gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CHML expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAATTCAGTT
About this image
See CHML Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CHML
SOURCE GeneReport for Unigene cluster: Hs.654545
SABiosciences Custom PCR Arrays for CHML
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHML
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CHML | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHML | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHML | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHML |
Orthologs
for CHML gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CHML gene from 8/26 species (see all 26) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
CHML6 |
choroideremia |
66(a) |
1 → many |
4(8622348-8681695) |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
66(a) |
1 → many |
GL343202.1(1229248-1282095) |
zebrafish
(Danio rerio) |
Actinopterygii |
chm6 |
choroideremia |
50(a) |
1 → many |
21(33652581-33759726) |
fruit fly
(Drosophila melanogaster) |
Insecta |
Rep3 |
neurotransmitter secretion RAB escort
protein |
33(a) |
|
56D13 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
Y67D2.13
rep-11 |
Protein REP-11 |
33(a)3
46.48(n)1
37.31(a)1 |
|
III(1642144-1648359)3
1753111 NM_001027757.21 NP_001022928.11 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
MRS61 |
Mrs6p |
46.87(n)
32.29(a) |
|
854552 NP_015015.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
REP1 |
Rab escort protein |
45.97(n)
32.28(a) |
|
819832 NM_111530.3 NP_187306.2 |
rice
(Oryza sativa) |
Liliopsida |
Os01g02691001 |
hypothetical protein |
47.42(n)
42.25(a) |
|
4326267 NM_001049232.1 NP_001042697.1 |
ENSEMBL Gene Tree for CHML (if available)
TreeFam Gene Tree for CHML (if available) |
Paralogs
for CHML gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CHML gene
- GDI12 GDI22 CHM2
1 SIMAP similar gene for CHML using alignment to 1 protein entry: RAE2_HUMAN:CHM
CHML for paralogs About GeneDecksing
|
Genomic Variants
for CHML gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CHML (241792155 - 241799232 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CHML: -- | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for CHML gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CHML for disorders About GeneDecksing
OMIM gene information: 118825
OMIM disorders: --
9  diseases for CHML: About MalaCardsusher syndrome type ii usher syndrome choroideremia kearns-sayre syndrome
intrahepatic cholangiocarcinoma multiple sclerosis cholangiocarcinoma asthma
choroiditis
2 diseases from the University of Copenhagen DISEASES database for CHML:Choroideremia Kearns-Sayre syndrome 1 Novoseek disease relationship for CHML gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| choroideremia |
93.8 |
1 |
8294464 (1) |
Human Genome Epidemiology (HuGE) Navigator: CHML (2 documents)
Export disorders for CHML gene to outside databases
|
Publications
for CHML gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CHML gene, integrated from 9 sources (see all 27):
(articles sorted by number of sources associating them with CHML) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- REP-2, a Rab escort protein encoded by the choroideremia-like gene. (PubMed id 8294464)1, 2, 9 Cremers F.P.M....Goldstein J.L. (1994)
- Cloning and characterization of the human choroideremia gene. (PubMed id 7981670)1, 3, 9 van Bokhoven H.... Cremers F.P. (1994)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Different structural organization of the encephalopsin gene in man and mouse. (PubMed id 12242008)1, 2 Kasper G.... Rump A. (2002)
- An autosomal homologue of the choroideremia gene colocalizes with the Usher syndrome type II locus on the distal part of chromosome 1q. (PubMed id 1301160)1, 2 Cremers F.P.M.... Ropers H.-H. (1992)
- Mapping of the choroideremia-like (CHML) gene at 1q42-qter and mutation analysis in patients with Usher syndrome type II. (PubMed id 8188272)1, 9 von Bokhoven H....Ropers H.H. (1994)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Follow-up examination of linkage and association to c hromosome 1q43 in multiple sclerosis. (PubMed id 19626040)1 McCauley J.L....Haines J.L. (2009)
|
External Searches for CHML gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CHML gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CHML gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CHML gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CHML | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CHML gene:
Search GeneIP for patents involving CHML
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CHML gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CHML | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CHML | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHML | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CHML | | OriGene 3'-UTR Clone for CHML | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHML | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHML | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CHML | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHML | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHML | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CHML | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHML | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHML |
| |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHML |
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