CHM Gene
protein-coding GIFtS: 62
GCID: GC0XM085116
|
|
choroideremia (Rab escort protein 1)
(Previous symbols: TCD, DXS540)
| |
Aliases
for CHM gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Choroideremia (Rab Escort Protein 1)1 2 | | Rab Proteins Geranylgeranyltransferase Component A 12 | | TCD1 2 3 5 | | REP13 | | REP-11 2 3 | | Choroideremia Protein3 | | DXS5401 2 | | Rab Escort Protein 13 | | GGTA2 | | TCD Protein3 | | HSD-322 | | |
Export aliases for CHM gene to outside databasesPrevious GC identifers: GC0XM080499 GC0XM082196 GC0XM083152 GC0XM083889 GC0XM083891 GC0XM084923 GC0XM085002 GC0XM078692 |
Summaries
for CHM gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CHM:
This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunitbinds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyltransfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminusto localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia; also known astapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid,retinal pigment epithelium and retina. Alternative splicing results in multiple transcript variants encoding differentisoforms.(provided by RefSeq, Feb 2009)
UniProtKB/Swiss-Prot: RAE1_HUMAN, P24386Function: Binds unprenylated Rab proteins, presents it to the catalytic Rab GGTase dimer, and remains bound to it afterthe geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rabback to the donor membrane. Also a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B)can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rabprotein geranylgeranylation
Gene Wiki entry for CHM (Rab escort protein)
|
Genomic Views
for CHM gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_011651.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CHM gene promoter:
AML1a
Other transcription factors
Search SABiosciences Chromatin IP Primers for CHM
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHM |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq21.2 Ensembl cytogenetic band: Xq21.2 HGNC cytogenetic band: Xq21.1-q21.3CHM Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XM085116: view genomic region
(about GC identifiers)
Start:
|
85,116,185 bp from pter |
End:
|
85,302,566 bp from pter |
Size:
|
186,382 bases |
Orientation:
|
minus strand |
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Proteins
for CHM gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RAE1_HUMAN, P24386 (See
protein sequence)Recommended Name: Rab proteins geranylgeranyltransferase component A 1 Size: 653 amino acids; 73476 Da
Subunit: Monomer. Can associate with the Rab GGTase dimer (RGGT or component B) prior to Rab protein binding; theassociation is stabilized by geranylgeranyl pyrophosphate (GGpp). The CHM:RGGT:Rab complex is destabilized by GGpp.Interacts with RAB1B; the interaction is required for RAB1B prenylation. Interacts with RABGGTA
Secondary accessions: A1L4D2 O43732Alternative splicing: 2 isoforms: P24386-1 P24386-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for CHM: NX_P24386
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P24386
CHM Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_000381.1 NP_001138886.1
ENSEMBL proteins: ENSP00000350386 ENSP00000362228 ENSP00000441728
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005968 | Rab-protein geranylgeranyltransferase complex |
IEA | -- |
CHM for ontologies About GeneDecksing
CHM Antibody Products:
Assay Products for CHM: |
Protein
Domains /
Families
for CHM gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CHM for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P24386ProtoNet protein and cluster: P24386 1 Blocks protein family: IPB001738 Rab escort (choroideraemia) protein signature
UniProtKB/Swiss-Prot: RAE1_HUMAN, P24386Similarity: Belongs to the Rab GDI family |
Function
for CHM gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: RAE1_HUMAN, P24386Function: Binds unprenylated Rab proteins, presents it to the catalytic Rab GGTase dimer, and remains bound to it afterthe geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rabback to the donor membrane. Also a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B)can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rabprotein geranylgeranylation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHM (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHM (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHM |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
CHM for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for CHM:
Animal Models:
Mouse knock-outs for CHM: Chmtm1.3Seab Chmtm1Jvdh Chmtm1.2Seab
9 MGI mutant phenotypes (inferred from 5 alleles ) (MGI details for Chm):
CHM for phenotypes About GeneDecksing
|
Pathways & Interactions
for CHM gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CHM
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/65 Interacting proteins for CHM (P243863 ENSP000003503864) via UniProtKB, MINT, STRING, and/or I2D (see all 65)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
CHM for ontologies About GeneDecksing
|
Drugs & Compounds
for CHM gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
CHM for compounds About GeneDecksing
 Browse Tocris compounds for CHM
1 DrugBank Compound for CHM About this table
7 Novoseek chemical compound relationships for CHM gene About this table
Search CenterWatch for drugs/clinical trials and news about CHM / RAE1
|
Transcripts
for CHM gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CHM gene (3 alternative transcripts): NM_000390.2 NM_001145414.1 NM_001037312.1 Unigene Cluster for CHM: Choroideremia (Rab escort protein 1) Hs.496449 [show with all ESTs]Unigene Representative Sequence: NM_0003906 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000357749(uc004eet.3 uc011mqz.2) ENST00000467744 ENST00000358786(uc004eeu.4 uc004eev.4)
ENST00000487515 ENST00000483950 ENST00000537751
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHM (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHM (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): CHM (NM_000390) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CHM | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHM |
Additional cDNA sequence: AK095883.1 AK291160.1 AK299323.1 AK312443.1 AY255796.1 BC032237.1 BC063522.1 BC065702.1 BC073987.1 BC105969.1 BC130494.1 BC130496.1 M83773.1 X57637.1 X78121.1 11 DOTS entries: DT.75178644 DT.121299419 DT.70103090 DT.413508 DT.102827417 DT.121299409 DT.40126657 DT.100749495 DT.121299453 DT.40106218 DT.95156019 24/104 AceView cDNA sequences (see all 104): AI432571 CB155362 AW089657 BQ632151 AL524494 AW613181 AV709873 BC032237 BU688880 AI910647 AA931465 BE501743 BM721494 BU738048 AI474660 X78121 BQ631852 AY255796 CD106837 AA878377 BM677132 BX484921 NM_000390 BM700393
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for CHM (see all 6) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10a | · | 10b |
|---|
|
| SP1: | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CHM
|
Expression
for CHM gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CHM expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AATATATGAT
About this image
See CHM Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CHM
SOURCE GeneReport for Unigene cluster: Hs.496449
SABiosciences Custom PCR Arrays for CHM
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHM
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CHM | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHM | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHM | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHM |
Orthologs
for CHM gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CHM gene from 8/25 species (see all 25) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
CHM1 |
choroideremia (Rab escort protein 1) |
69.98(n)
66.56(a) |
|
422266 NM_001031119.1 NP_001026290.1 |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
65(a) |
1 → many |
GL343202.1(1229248-1282095) |
African clawed frog
(Xenopus laevis) |
Amphibia |
MGC685782 |
choroideremia (Rab escort protein 1) |
74.06(n) |
|
BC061662.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.170402 |
Danio rerio Rab escort protein 1 (chm) mRNA, complete more |
74.34(n) |
|
AY500891.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Rep1 , 3 |
neurotransmitter secretion RAB escort
protein3
Rab escort protein1 |
34(a)3
46.41(n)1
39.43(a)1 |
|
56D133
372461 NM_058072.31 NP_477420.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
Y67D2.13 |
-- |
30(a) |
|
III(1642144-1648359) -- |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
REP6 |
Rab escort protein |
25(a) |
1 → many |
3(2035003-2037788) |
rice
(Oryza sativa) |
Liliopsida |
-- |
rab GDP dissociation inhibitor alpha, putative, ex... |
30(a) |
1 → many |
1(9272876-9278032) |
ENSEMBL Gene Tree for CHM (if available)
TreeFam Gene Tree for CHM (if available) |
Paralogs
for CHM gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CHM gene
- GDI12 CHML2 GDI22
2 SIMAP similar genes for CHM using alignment to 3 protein entries: RAE1_HUMAN (see all proteins):CHML GDI2
CHM for paralogs About GeneDecksing
|
Genomic Variants
for CHM gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CHM (85116185 - 85302566 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for CHM
1 CNV: 1855
Human Gene Mutation Database (HGMD): CHM
Locus Specific Mutation Databases (LSDB): CHM
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHM |
|
Disorders
/ Diseases
for CHM gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CHM for disorders About GeneDecksing
OMIM gene information: 300390
OMIM disorders: 303100
UniProtKB/Swiss-Prot: RAE1_HUMAN, P24386
Defects in CHM are the cause of choroideremia (CHM) [MIM:303100]. An X-linked recessive disease characterizedby a slowly progressive degeneration of the choroid, photoreceptors, and retinal pigment epithelium. Affected malesdevelop night blindness in their teenage years followed by loss of peripheral vision and complete blindness at middleage. Carrier females are generally asymptomatic but funduscopic examination often shows patchy areas of chorioretinalatrophy
17  diseases for CHM: About MalaCardschoroideremia martin-probst deafness-mental retardation syndrome x-linked disease choroiditis
retinitis gestational trophoblastic neoplasm trophoblastic neoplasm mental retardation syndrome
chorioretinal atrophy chorioretinitis pigmentary retinopathy night blindness
retinal degeneration eye disease parkinson's disease blindness
choriocarcinoma
2 diseases from the University of Copenhagen DISEASES database for CHM:Choroideremia Parkinson's disease 7 Novoseek disease relationships for CHM gene About this table
Genatlas disease: CHM choroideremia
GeneTests: CHM
Choroideremia
Genetic Association Database (GAD): CHM
Export disorders for CHM gene to outside databases
|
Publications
for CHM gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CHM gene, integrated from 9 sources (see all 109):
(articles sorted by number of sources associating them with CHM) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The functional effect of pathogenic mutations in Rab escort protein 1. (PubMed id 19427510)1, 2, 9 Sergeev Y.V....Macdonald I.M. (2009)
- Rab escort protein-1 is a multifunctional protein that accompanies newly prenylated rab proteins to their target membranes. (PubMed id 7957092)1, 2, 9 Alexandrov K....Zerial M. (1994)
- Comprehensive mutation analysis (20 families) of the choroideremia gene reveals a missense variant that prevents the binding of REP1 with rab geranylgeranyl transferase. (PubMed id 21905166)1, 2 Esposito G.... Salvatore F. (2011)
- Rab geranylgeranylation occurs preferentially via the pre-formed REP-RGGT complex and is regulated by geranylgeranyl pyrophosphate. (PubMed id 18532927)1, 2 Baron R.A. and Seabra M.C. (2008)
- The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
- Missense mutation in the choroideremia gene. (PubMed id 7951216)1, 2 Donnelly P.... Pascal O. (1994)
- Cloning and characterization of the human choroideremia gene. (PubMed id 7981670)1, 2 van Bokhoven H.... Cremers F.P. (1994)
- Detection and characterization of point mutations in the choroideremia candidate gene by PCR-SSCP analysis and direct DNA sequencing. (PubMed id 1598901)1, 2 van den Hurk J.A.J.M.... Cremers F.P.M. (1992)
- Isolation of a candidate gene for choroideremia. (PubMed id 1549574)1, 2 Merry D.E.... Nussbaum R.L. (1992)
- Three RFLPs for pZ11 (DXS540) in the choroideremia gene at Xq21.2. (PubMed id 1373238)1, 3 Molloy C.M....Cremers F.P. (1992)
|
External Searches for CHM gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CHM gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CHM gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CHM gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CHM | Pharmacogenomics, SNPs, Pathways | | ATLAS Chromosomes in Cancer entry for CHM | Genetics and Cytogenetics in Oncology and Haematology | | Mutations of the REP1 gene | http://www.retina-international.org/files/sci-news/repmut.htm | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/CHM |
|
| | |
About This Section
| Patent Information for CHM gene:
Search GeneIP for patents involving CHM
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CHM gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for CHM | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CHM | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHM | | | OriGene Protein Over-expression Lysate for CHM | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CHM | | OriGene 3'-UTR Clone for CHM | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHM | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHM | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CHM | | OriGene Custom Protein Services for CHM | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CHM | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHM | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHM | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CHM | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHM | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHM |
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| | | | Search Tocris compounds for CHM |
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 | | | CHM Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHM |
|  |  |  | | | | Search ThermoFisher Antibodies for CHM |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHM |
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