CHKB-CPT1B Gene
protein-coding GIFtS: 23
GCID: GC22M051010
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CHKB-CPT1B readthrough (non-protein coding)
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Aliases
for CHKB-CPT1B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
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| CHKB-CPT1B Readthrough (Non-Protein Coding)1 2 | | CHKL-CPT1B2 |
| External Ids: | HGNC: 419981 | Entrez Gene: 3865932 | Ensembl: ENSG000002544137 | UniProtKB: H3BT564 | | ORGUL members: | |
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| NONCODE:n408072 | |
Export aliases for CHKB-CPT1B gene to outside databasesPrevious GC identifers: GC22M049297 GC22M049355 GC22M051009
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Summaries
for CHKB-CPT1B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CHKB-CPT1B:
The genes CHKB and CPT1B are adjacent on chromosome 22 and read-through transcripts are expressed that include exonsfrom both loci. The read-through transcripts are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely toexpress proteins. (provided by RefSeq, Jun 2009)
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Genomic Views
for CHKB-CPT1B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for CHKB-CPT1B
Other transcription factors
Search SABiosciences Chromatin IP Primers for CHKB-CPT1B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHKB-CPT1B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22q13.33 Ensembl cytogenetic band: 22q13.33 HGNC cytogenetic band: 22q13.33CHKB-CPT1B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22M051010: view genomic region
(about GC identifiers)
Start:
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51,007,290 bp from pter |
End:
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51,021,428 bp from pter |
Size:
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14,139 bases |
Orientation:
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minus strand |
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Proteins
for CHKB-CPT1B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/TrEMBL: H3BT56 (See
protein sequence)Recommended Name: Protein CHKB-CPT1B Size: 60 amino acids; 7003 Da
Secondary accessions: J3KQX7CHKB-CPT1B Protein expression data from MOPED and PaxDb: --
ENSEMBL proteins: ENSP00000457031
Human Recombinant Protein Products:
CHKB-CPT1B Antibody Products:
Assay Products for CHKB-CPT1B: |
Protein
Domains /
Families
for CHKB-CPT1B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
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CHKB-CPT1B for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry H3BT56ProtoNet protein and cluster: H3BT56 |
Function
for CHKB-CPT1B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHKB-CPT1B |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
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| GO:0016772 | transferase activity, transferring phosphorus-containing groups |
-- | -- |
CHKB-CPT1B for ontologies About GeneDecksing
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Pathways & Interactions
for CHKB-CPT1B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CHKB-CPT1B
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Drugs & Compounds
for CHKB-CPT1B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CHKB-CPT1B
Search CenterWatch for drugs/clinical trials and news about CHKB-CPT1B 
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Transcripts
for CHKB-CPT1B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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3 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000492556(uc003bmp.3 uc021wsc.1 uc003bmu.3) ENST00000453634
ENST00000452668
GeneLoc Exon Structure
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Expression
for CHKB-CPT1B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CHKB-CPT1B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
Genevestigator expression for CHKB-CPT1B
SABiosciences Custom PCR Arrays for CHKB-CPT1B
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat CHKB-CPT1B | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHKB-CPT1B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHKB-CPT1B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHKB-CPT1B |
Orthologs
for CHKB-CPT1B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of eukaryotes.
Orthologs for CHKB-CPT1B gene from 6/19 species (see all 19) About this table
ENSEMBL Gene Tree for CHKB-CPT1B (if available)
TreeFam Gene Tree for CHKB-CPT1B (if available) |
Paralogs
for CHKB-CPT1B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CHKB-CPT1B gene
- CHKA2 CHKB2 ETNK12 ETNK22
1 SIMAP similar gene for CHKB-CPT1B using alignment to 1 protein entry: H3BT56_HUMAN:ETNK2
CHKB-CPT1B for paralogs About GeneDecksing
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Genomic Variants
for CHKB-CPT1B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for CHKB-CPT1B
3 CNVs: 4139 5192 7354 | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for CHKB-CPT1B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
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CHKB-CPT1B for disorders About GeneDecksing
1  disease for CHKB-CPT1B: About MalaCardsmalaria
Export disorders for CHKB-CPT1B gene to outside databases
|
Publications
for CHKB-CPT1B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CHKB-CPT1B gene integrated from 9 sources:
(articles sorted by number of sources associating them with CHKB-CPT1B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PubMed id 20967262)1 Prakash T....Taylor T.D. (2010)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Identification of novel transcribed sequences on human chromosome 22 by expressed sequence tag mapping. (PubMed id 11258795)1 Hirosawa M....Ohara O. (2001)
- Novel expression of equivocal messages containing both regions of choline/ethanolamine kinase and muscle type carnitine palmitoyltransferase I. (PubMed id 10918069)1 Yamazaki N.... Terada H. (2000)
- Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PubMed id 10493829)1 Loftus B.J.... Adams M.D. (1999)
- Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
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External Searches for CHKB-CPT1B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing CHKB-CPT1B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing CHKB-CPT1B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CHKB-CPT1B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
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About This Section
| Patent Information for CHKB-CPT1B gene:
Search GeneIP for patents involving CHKB-CPT1B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CHKB-CPT1B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CHKB-CPT1B | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHKB-CPT1B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHKB-CPT1B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CHKB-CPT1B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHKB-CPT1B | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHKB-CPT1B |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHKB-CPT1B |
|  |  |  | | | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CHKB-CPT1B |
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