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Aliases for CHKB-CPT1B Gene

Subcategory (RNA class) for CHKB-CPT1B Gene

ncRNA

Quality Score for this RNA gene is

3

Aliases for CHKB-CPT1B Gene

  • CHKB-CPT1B Readthrough (NMD Candidate) 2 3
  • Choline Kinase-Like, Carnitine Palmitoyltransferase 1B (Muscle) Transcription Unit 3
  • CHKB-CPT1B Readthrough (Non-Protein Coding) 3
  • CHKL-CPT1B 3

External Ids for CHKB-CPT1B Gene

Summaries for CHKB-CPT1B Gene

Entrez Gene Summary for CHKB-CPT1B Gene

  • The genes CHKB and CPT1B are adjacent on chromosome 22 and read-through transcripts are expressed that include exons from both loci. The read-through transcripts are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to express proteins. [provided by RefSeq, Jun 2009]

GeneCards Summary for CHKB-CPT1B Gene

CHKB-CPT1B (CHKB-CPT1B Readthrough (NMD Candidate)) is a RNA Gene, and belongs to ncRNA RNA class. Diseases associated with CHKB-CPT1B include narcolepsy. An important paralog of this gene is CHKB.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CHKB-CPT1B Gene

Genomics for CHKB-CPT1B Gene

Genomic Location for CHKB-CPT1B Gene

Start:
50,568,861 bp from pter
End:
50,582,999 bp from pter
Size:
14,139 bases
Orientation:
Minus strand

Genomic View for CHKB-CPT1B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CHKB-CPT1B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CHKB-CPT1B Gene

No data available for Regulatory Elements for CHKB-CPT1B Gene

Proteins for CHKB-CPT1B Gene

  • Protein details for CHKB-CPT1B Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    H3BT56-H3BT56
    Recommended name:
    Protein CHKB-CPT1B
    Protein Accession:
    H3BT56
    Secondary Accessions:
    • J3KQX7

    Protein attributes for CHKB-CPT1B Gene

    Size:
    60 amino acids
    Molecular mass:
    7003 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CHKB-CPT1B Gene

Proteomics data for CHKB-CPT1B Gene at MOPED

Post-translational modifications for CHKB-CPT1B Gene

No Post-translational modifications

Other Protein References for CHKB-CPT1B Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for CHKB-CPT1B Gene

Domains for CHKB-CPT1B Gene

Protein Domains for CHKB-CPT1B Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with CHKB-CPT1B: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CHKB-CPT1B Gene

Function for CHKB-CPT1B Gene

Gene Ontology (GO) - Molecular Function for CHKB-CPT1B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016772 transferase activity, transferring phosphorus-containing groups --
genes like me logo Genes that share ontologies with CHKB-CPT1B: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CHKB-CPT1B Gene

Localization for CHKB-CPT1B Gene

No data available for Gene Ontology (GO) - Cellular Components for CHKB-CPT1B Gene

Pathways for CHKB-CPT1B Gene

SuperPathways for CHKB-CPT1B Gene

No Data Available

Interacting Proteins for CHKB-CPT1B Gene

Gene Ontology (GO) - Biological Process for CHKB-CPT1B Gene

None

No data available for Pathways by source for CHKB-CPT1B Gene

Transcripts for CHKB-CPT1B Gene

mRNA/cDNA for CHKB-CPT1B Gene

(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CHKB-CPT1B Gene

No ASD Table

Relevant External Links for CHKB-CPT1B Gene

GeneLoc Exon Structure for
CHKB-CPT1B
ECgene alternative splicing isoforms for
CHKB-CPT1B

Expression for CHKB-CPT1B Gene

mRNA expression in normal human tissues for CHKB-CPT1B Gene

genes like me logo Genes that share expressions with CHKB-CPT1B: view

Orthologs for CHKB-CPT1B Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for CHKB-CPT1B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CHKB 37
  • 15 (a)
OneToMany
cow
(Bos Taurus)
Mammalia CHKB 37
  • 13 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 37
  • 20 (a)
OneToMany
mouse
(Mus musculus)
Mammalia BC090627 16
Chkb 37
  • 13 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 10 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 19 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
OneToMany
zebrafish
(Danio rerio)
Actinopterygii chkb 37
  • 8 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG2201 37
  • 3 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea cka-1 37
  • 4 (a)
ManyToMany
cka-2 37
  • 6 (a)
ManyToMany
ckb-1 37
  • 3 (a)
ManyToMany
ckb-2 37
  • 3 (a)
ManyToMany
ckb-3 37
  • 3 (a)
ManyToMany
ckb-4 37
  • 4 (a)
ManyToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes CKI1 37
  • 2 (a)
ManyToMany
EKI1 37
  • 2 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 7 (a)
OneToMany
Species with no ortholog for CHKB-CPT1B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for CHKB-CPT1B Gene

ENSEMBL:
Gene Tree for CHKB-CPT1B (if available)
TreeFam:
Gene Tree for CHKB-CPT1B (if available)

Paralogs for CHKB-CPT1B Gene

Paralogs for CHKB-CPT1B Gene

Selected SIMAP similar genes for CHKB-CPT1B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CHKB-CPT1B: view

Variants for CHKB-CPT1B Gene

Structural Variations from Database of Genomic Variants (DGV) for CHKB-CPT1B Gene

Variant ID Type Subtype PubMed ID
nsv915495 CNV Loss 21882294
nsv914525 CNV Loss 21882294
dgv5062n71 CNV Loss 21882294
nsv471224 CNV Loss 18288195
nsv914542 CNV Loss 21882294
nsv914543 CNV Loss 21882294
nsv834239 CNV Loss 17160897
dgv1422e1 CNV Complex 17122850
dgv5066n71 CNV Loss 21882294
nsv829340 CNV Gain 20364138
dgv5067n71 CNV Loss 21882294
nsv914559 CNV Loss 21882294
esv33185 CNV Loss 17666407
nsv914561 CNV Loss 21882294
dgv5068n71 CNV Loss 21882294

Relevant External Links for CHKB-CPT1B Gene

HapMap Linkage Disequilibrium report
CHKB-CPT1B

No data available for Sequence variations from dbSNP and Humsavar for CHKB-CPT1B Gene

Disorders for CHKB-CPT1B Gene

(1) MalaCards Diseases for CHKB-CPT1B Gene

Search for CHKB-CPT1B Gene in MalaCards »
genes like me logo Genes that share disorders with CHKB-CPT1B: view

No data available for UniProtKB/Swiss-Prot for CHKB-CPT1B Gene

Publications for CHKB-CPT1B Gene

  1. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3
  2. Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PMID: 10493829) Loftus B.J. … Adams M.D. (Genomics 1999) 3
  3. Novel expression of equivocal messages containing both regions of choline/ethanolamine kinase and muscle type carnitine palmitoyltransferase I. (PMID: 10918069) Yamazaki N. … Terada H. (J. Biol. Chem. 2000) 3
  4. Identification of novel transcribed sequences on human chromosome 22 by expressed sequence tag mapping. (PMID: 11258795) Hirosawa M. … Ohara O. (DNA Res. 2001) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for CHKB-CPT1B Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate CHKB-CPT1B
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for CHKB-CPT1B
    • Block miRNA regulation of CHKB-CPT1B using miScript Target Protectors

    Sources for CHKB-CPT1B Gene

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