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protein-coding   GIFtS: 61
GCID: GC22M051017

Choline Kinase Beta

(Previous name: choline kinase-like)
(Previous symbol: CHKL)
  See CHKB-related diseases

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Choline Kinase Beta1 2 3     EK2 3
CHKL1 2 3 5     MDCMC2 5
CKEKB2 3 5     Choline Kinase-Like1
EKB2 3 5     Choline/Ethanolamine Kinase2
Choline Kinase-Like Protein2 3     EC
Ethanolamine Kinase Beta2 3     EC
CHETK2 3     Choline/Ethanolamine Kinase Beta3
CK2 3     Ethanolamine Kinase3
CKB2 3     

External Ids:    HGNC: 19381   Entrez Gene: 11202   Ensembl: ENSG000001002887   OMIM: 6123955   UniProtKB: Q9Y2593   

Export aliases for CHKB gene to outside databases

Previous GC identifiers: GC22M049149 GC22M049298 GC22M049307 GC22M049364 GC22M051007 GC22M033908

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CHKB Gene:
Choline kinase (CK) and ethanolamine kinase (EK) catalyze the phosphorylation of choline/ethanolamine to
phosphocholine/phosphoethanolamine. This is the first enzyme in the biosynthesis of
phosphatidylcholine/phosphatidylethanolamine in all animal cells. The highly purified CKs from mammalian sources
and their recombinant gene products have been shown to have EK activity also, indicating that both activities
reside on the same protein. The choline kinase-like protein encoded by CHKL belongs to the choline/ethanolamine
kinase family; however, its exact function is not known. Read-through transcripts are expressed from this locus
that include exons from the downstream CPT1B locus. (provided by RefSeq, Jun 2009)

GeneCards Summary for CHKB Gene:
CHKB (choline kinase beta) is a protein-coding gene. Diseases associated with CHKB include spermatic cord torsion, and japanese spotted fever. GO annotations related to this gene include ethanolamine kinase activity and choline kinase activity. An important paralog of this gene is CHKA.

UniProtKB/Swiss-Prot: CHKB_HUMAN, Q9Y259
Function: Has a key role in phospholipid biosynthesis. Catalyzes the first step in phosphatidylethanolamine
biosynthesis. Phosphorylates ethanolamine, and can also act on choline (in vitro). Has higher activity with
ethanolamine. May not significantly contribute to in vivo phosphatidylcholine biosynthesis

Gene Wiki entry for CHKB Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence at NCBI GenBank:
NC_000022.10  NC_018933.2  NT_011526.8  
Regulatory elements:
   Regulatory transcription factor binding sites in the CHKB gene promoter:
         PPAR-gamma1   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCHKB promoter sequence
   Search Chromatin IP Primers for CHKB

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CHKB

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.33   Ensembl cytogenetic band:  22q13.33   HGNC cytogenetic band: 22q13.33

CHKB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CHKB gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22M051017:  view genomic region     (about GC identifiers)

51,017,378 bp from pter      End:
51,039,884 bp from pter
22,507 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, antibodies-online, and/or GeneTex,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or GeneTex.)
About This Section

UniProtKB/Swiss-Prot: CHKB_HUMAN, Q9Y259 (See protein sequence)
Recommended Name: Choline/ethanolamine kinase  
Size: 395 amino acids; 45271 Da
Subunit: Homodimer, and heterodimer with CHKA
Miscellaneous: This protein is produced by a bicistronic gene which also produces the CPT1B protein from a
non-overlapping reading frame
Sequence caution: Sequence=AAB03342.2; Type=Erroneous gene model prediction;
3 PDB 3D structures from and Proteopedia for CHKB:
2IG7 (3D)        3FEG (3D)        3LQ3 (3D)    
Secondary accessions: A0PJM6 Q13388
Alternative splicing: 2 isoforms:  Q9Y259-1   Q9Y259-2   

Explore the universe of human proteins at neXtProt for CHKB: NX_Q9Y259

Explore proteomics data for CHKB at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CHKB Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_005189.2  
    ENSEMBL proteins: 
    Reactome Protein details: Q9Y259

    CHKB Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    R&D Systems Recombinant & Natural Proteins for CHKB (Choline Kinase beta)
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Proteins for CHKB
    OriGene Protein Over-expression Lysate for CHKB
    OriGene MassSpec for CHKB
    OriGene Custom Protein Services for CHKB
    GenScript Custom Purified and Recombinant Proteins Services for CHKB
    Novus Biologicals CHKB Protein
    Novus Biologicals CHKB Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

    Search eBioscience for Proteins for CHKB 

    antibodies-online proteins for CHKB (4 products) 

    antibodies-online peptides for CHKB

    Search GeneTex for Proteins for CHKB 

    CHKB Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for CHKB
    OriGene Custom Antibody Services for CHKB
    Novus Biologicals CHKB Antibodies
    Abcam antibodies for CHKB
    Browse Antibodies at Cloud-Clone Corp.
    ThermoFisher Antibodies for CHKB
    antibodies-online antibodies for CHKB (30 products) 

    GeneTex Antibodies for CHKB:  
                        CHKB Antibodies

    CHKB Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CHKB
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CHKB
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for CHKB 
    antibodies-online kits for CHKB (6 products) 

    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GenesLikeMe)
    About This Section

    1 InterPro protein domain:
     IPR011009 Kinase-like_dom

    Graphical View of Domain Structure for InterPro Entry Q9Y259

    ProtoNet protein and cluster: Q9Y259

    1 Blocks protein domain: IPB002573 Choline/ethanolamine kinase

    UniProtKB/Swiss-Prot: CHKB_HUMAN, Q9Y259
    Similarity: Belongs to the choline/ethanolamine kinase family

    Find genes that share domains with CHKB           About GenesLikeMe

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway, and/or Taconic Biosciences, CRISPR knockouts from OriGene, transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Clones from OriGene, GenScript, Sino Biological, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CHKB_HUMAN, Q9Y259
    Function: Has a key role in phospholipid biosynthesis. Catalyzes the first step in phosphatidylethanolamine
    biosynthesis. Phosphorylates ethanolamine, and can also act on choline (in vitro). Has higher activity with
    ethanolamine. May not significantly contribute to in vivo phosphatidylcholine biosynthesis
    Catalytic activity: ATP + choline = ADP + phosphocholine
    Catalytic activity: ATP + ethanolamine = ADP + O-phosphoethanolamine
    Biophysicochemical properties: Kinetic parameters: KM=0.57 mM for choline; KM=2.9 mM for ethanolamine;

         Enzyme Numbers (IUBMB): EC EC

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004103choline kinase activity IDA19915674
    GO:0004305ethanolamine kinase activity IDA19915674
    GO:0005524ATP binding IEA--
    GO:0016772transferase activity, transferring phosphorus-containing groups ----
    Find genes that share ontologies with CHKB           About GenesLikeMe

         6 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Chkb):
     behavior/neurological  homeostasis/metabolism  limbs/digits/tail  muscle  nervous system 

    Find genes that share phenotypes with CHKB           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for CHKB

        Taconic Biosciences Mouse Models for CHKB:  
                        TF3031 - Chkb

    CRISPR Knockouts: 
       OriGene CRISPR knockouts for CHKB

    miRTarBase miRNAs that target CHKB:
    hsa-let-7b-5p (MIRT052190), hsa-mir-196b-5p (MIRT042674), hsa-mir-92a-3p (MIRT049124), hsa-mir-320a (MIRT044642), hsa-mir-346 (MIRT042718), hsa-mir-324-5p (MIRT043074), hsa-mir-744-5p (MIRT037448), hsa-mir-935 (MIRT036653), hsa-mir-1260b (MIRT052723)

    Block miRNA regulation of human, mouse, rat CHKB using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate CHKB:
    hsa-miR-146b-3p hsa-miR-4254 hsa-miR-874 hsa-miR-4308
    SwitchGear 3'UTR luciferase reporter plasmidCHKB 3' UTR sequence
    Inhib. RNA
    OriGene RNAi products in human, mouse, rat for CHKB
    Predesigned siRNA for gene silencing in human, mouse, rat CHKB

    OriGene clones in human, mouse for CHKB (see all 13)
    OriGene ORF clones in mouse, rat for CHKB
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CHKB (NM_005198)
    Browse Sino Biological Human cDNA Clones
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHKB
    Addgene plasmids for CHKB 

    Cell Line
    GenScript Custom overexpressing Cell Line Services for CHKB
    Browse ESI BIO Cell Lines and PureStem Progenitors for CHKB 
    In Situ Assay

    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHKB

    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
    About This Section

    Subcellular locations from COMPARTMENTS: 


    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ----
    GO:0005829cytosol TAS--

    Find genes that share ontologies with CHKB           About GenesLikeMe

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GenesLikeMe, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
    About This Section

    SuperPaths for CHKB About    
    See pathways by source

    SuperPathContained pathways About
    1Glycerophospholipid biosynthesis
    Glycerophospholipid biosynthesis0.64
    Synthesis of PE0.00
    Phospholipid metabolism0.64
    Synthesis of PC0.00
    Glycerophospholipid metabolism0.62
    Metabolism of lipids and lipoproteins0.37
    Metabolic pathways0.38
    3Mitochondrial LC-Fatty Acid Beta-Oxidation
    Fatty Acid Beta Oxidation0.35

    Find genes that share SuperPaths with CHKB           About GenesLikeMe

    Pathways by source                                   See SuperPaths
    Show all pathways

    1 BioSystems Pathway for CHKB
        Fatty Acid Beta Oxidation

    2 Reactome Pathways for CHKB
        Synthesis of PE
    Synthesis of PC

    2 Kegg Pathways  (Kegg details for CHKB):
        Glycerophospholipid metabolism
    Metabolic pathways

    UniProtKB/Swiss-Prot: CHKB_HUMAN, Q9Y259
    Pathway: Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from
    ethanolamine: step 1/3

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CHKB

        Search GeneGlobe Interaction Network for CHKB

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for CHKB (Q9Y2593 ENSP000003844004) via UniProtKB, MINT, STRING, and/or I2D (see all 82)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000206286Q8N1B43I2D: score=1 
    ENSG00000224455Q8N1B43I2D: score=1 
    ENSG00000225590Q8N1B43I2D: score=1 
    ENSG00000228425Q8N1B43I2D: score=1 
    ENSG00000236014Q8N1B43I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006644phospholipid metabolic process TAS--
    GO:0006646phosphatidylethanolamine biosynthetic process TAS--
    GO:0006656phosphatidylcholine biosynthetic process TAS--
    GO:0006657CDP-choline pathway IDA19915674
    GO:0044281small molecule metabolic process TAS--

    Find genes that share ontologies with CHKB           About GenesLikeMe

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, Sets of similar genes according to GenesLikeMe)
    About This Section

    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CHKB

    6 HMDB Compounds for CHKB    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    Choline(2-Hydroxyethyl)trimethyl ammonium (see all 19)62-49-7--
    Ethanolamine1-Amino-2-hydroxyethane (see all 28)141-43-5--
    O-PhosphoethanolaminePhosphoryethanolamine (see all 28)1071-23-4--
    PhosphorylcholineCholine phosphate (see all 5)3616-04-4--

    1 DrugBank Compound for CHKB    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    CholineBilineurine (see all 7)62-49-7enzymesubstrate16371353 17236204

    Selected Novoseek inferred chemical compound relationships for CHKB gene (see all 146)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    creatinine 95.3 1967 16324360 (4), 7736901 (3), 1764545 (3), 8873665 (3) (see all 99)
    cyclocreatine 75.9 17 7923134 (3), 11745437 (2), 8042860 (1), 9888469 (1) (see all 6)
    lactate 75.5 270 11108185 (3), 8557926 (3), 17650795 (3), 8358570 (2) (see all 99)
    aspartate 71.7 140 19254158 (2), 19421954 (2), 12639201 (2), 14642073 (2) (see all 99)
    alpha-hydroxybutyrate 71.2 9 2046229 (1), 9453514 (1), 10370734 (1), 18971188 (1) (see all 9)
    phosphocreatine 69.3 60 19332463 (4), 8276423 (3), 9746337 (2), 8635232 (2) (see all 30)
    alanine 50.5 62 12639201 (2), 9216454 (1), 11018813 (1), 15754570 (1) (see all 59)
    adp 41.4 27 8276423 (3), 8797846 (2), 9479037 (1), 9746337 (1) (see all 15)
    dantrolene 40.3 14 14649364 (3), 14719706 (3), 15717469 (2), 7486044 (2) (see all 5)
    atp 40.3 98 10387096 (4), 19332463 (4), 9764442 (3), 15647364 (3) (see all 52)

    Find genes that share compounds with CHKB           About GenesLikeMe

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    REFSEQ mRNAs for CHKB gene (2 alternative transcripts): 
    NM_005198.4  NM_152253.1  

    Unigene Cluster for CHKB:

    Choline kinase beta
    Hs.654827  [show with all ESTs]
    Unigene Representative Sequence: NM_005198
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000406938(uc003bmv.3) ENST00000492582(uc003bmt.2) ENST00000464225
    ENST00000471515 ENST00000484266 ENST00000481673 ENST00000479003 ENST00000468532
    ENST00000489453 ENST00000476289 ENST00000463053 ENST00000465842
    Block miRNA regulation of human, mouse, rat CHKB using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate CHKB:
    hsa-miR-146b-3p hsa-miR-4254 hsa-miR-874 hsa-miR-4308
    SwitchGear 3'UTR luciferase reporter plasmidCHKB 3' UTR sequence
    Inhib. RNA
    OriGene RNAi products in human, mouse, rat for CHKB
    Predesigned siRNA for gene silencing in human, mouse, rat CHKB
    OriGene clones in human, mouse for CHKB (see all 13)
    OriGene ORF clones in mouse, rat for CHKB
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CHKB (NM_005198)
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHKB
    Addgene plasmids for CHKB 
    OriGene qPCR primer pairs and template standards for CHKB
    OriGene qSTAR qPCR primer pairs in human, mouse for CHKB
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat CHKB
      QuantiTect SYBR Green Assays in human, mouse, rat CHKB
      QuantiFast Probe-based Assays in human, mouse, rat CHKB

    Additional mRNA sequence: 

    AB029886.1 AK314324.1 AL096780.1 AL096781.1 BC024286.1 BC050443.1 BC082263.1 BC101488.1 
    BC113521.1 BC141974.1 BC150582.1 CR456419.1 

    23 DOTS entries:

    DT.100838063  DT.444144  DT.100866086  DT.95264267  DT.102835430  DT.95239121  DT.91825945  DT.97770629 
    DT.97791231  DT.100835220  DT.95073240  DT.97846203  DT.100866077  DT.100662643  DT.100767679  DT.120661725 
    DT.120661774  DT.87003770  DT.91978213  DT.120661788  DT.100653056  DT.100703190  DT.100866072 

    Selected AceView cDNA sequences (see all 50):

    AW163316 CD364730 BM702182 BI494180 AA761255 BX331471 BM695582 BX355944 
    BX346470 W72661 AA149411 T53978 BE247467 AW771894 AA743869 AI268288 
    BU726575 AA465477 W73539 BM923362 W76418 AW612501 BX391233 AW157517 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CHKB (see all 29)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b · 3c · 3d ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13a · 13b ·
    SP1:                                                        -     -           -           -                                                     -     -     -   
    SP5:                          -           -                 -     -           -           -                                                                     

    ExUns: 13c ^ 14a · 14b ^ 15a · 15b · 15c · 15d ^ 16a · 16b · 16c ^ 17a · 17b · 17c · 17d · 17e ^ 18a · 18b · 18c · 18d ^ 19a · 19b · 19c ^ 20a · 20b ^ 21a · 21b ^
    SP1:  -     -     -     -     -                                                     -     -                                                           -         
    SP2:                    -     -                                                     -     -                                                           -         
    SP3:                    -     -                                                     -     -                                                           -         
    SP4:                                                                                -     -                                                           -         

    ExUns: 22a · 22b · 22c ^ 23a · 23b ^ 24 ^ 25a · 25b ^ 26a · 26b ^ 27a · 27b ^ 28 ^ 29 ^ 30 ^ 31a · 31b ^ 32 ^ 33a · 33b · 33c ^ 34a · 34b
    SP1:                    -     -           -                             -                                                     -               
    SP2:                    -     -           -                             -                                               -     -               
    SP3:                    -     -           -                             -                                                                     
    SP4:                    -     -           -                             -                                               -     -               

    ECgene alternative splicing isoforms for CHKB

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GenesLikeMe, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CHKB expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CHKB Expression
    About this image

    CHKB expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     Brain (Nervous System)    fully expand to see all 5 entries
             Cerebral Cortex
     Neural Tube (Nervous System)    fully expand to see all 3 entries
     Eye (Sensory Organs)
     Heart (Cardiovascular System)
     Placenta (Extraembryonic Tissues)
    CHKB Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CHKB Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.654827
        Custom PCR Arrays for CHKB
    OriGene qPCR primer pairs and template standards for CHKB
    OriGene qSTAR qPCR primer pairs in human, mouse for CHKB
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat CHKB
    QuantiTect SYBR Green Assays in human, mouse, rat CHKB
    QuantiFast Probe-based Assays in human, mouse, rat CHKB
    In Situ
    Assay Products:

    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHKB

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CHKB gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    Gene Description Human
    (Mus musculus)
    Mammalia Chkb1 , 5 choline kinase beta1, 5 85.11(n)1
      15 (44.89 cM)5
    126511  NM_007692.61  NP_031718.11 
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    1 → many
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia chkb1 choline kinase beta 60.59(n)
      100145186  NM_001126676.1  NP_001120148.1 
    (Danio rerio)
    Actinopterygii chkb1 choline kinase beta 62.95(n)
      563589  NM_001100012.2  NP_001093482.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG22011 CG2201 49.46(n)
      35417  NM_165387.3  NP_724349.1 
    (Caenorhabditis elegans)
    Secernentea cka-11 cka-1 49.95(n)
      177807  NM_001136377.2  NP_001129849.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes EKI16
    Ethanolamine kinase, primarily responsible for pho...
    Choline kinase, catalyzing the first step in phosp...
    many ↔ many
    many ↔ many
    IV(751631-753235) YDR147W
    XII(408445-410193) YLR133W
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G743201 AT1G74320 46.89(n)
      843772  NM_106092.3  NP_177572.2 
    (Oryza sativa)
    Liliopsida Os05g05354001 Os05g0535400 50(n)
      9268113  NM_001187573.1  NP_001174502.1 

    ENSEMBL Gene Tree for CHKB (if available)
    TreeFam Gene Tree for CHKB (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to Build 68,Sets of similar genes according to GenesLikeMe)
    About This Section

    Paralogs for CHKB gene
    CHKA2  ETNK12  CHKB-CPT1B2  ETNK22  
    2 SIMAP similar genes for CHKB using alignment to 1 protein entry:     CHKB_HUMAN:
    CHKA    ETNK2

    Find genes that share paralogs with CHKB           About GenesLikeMe

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and 4UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    Selected SNPs for CHKB (see all 41)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    Chr 22 posSequence#AA
    C--33913778(-) TTTTT-/TTTT  
    1 -- us2k10--------
    C,F,H--34965120(-) CAATGT/GGAGGT 1 -- us2k112Minor allele frequency- G:0.28MN NA WA CSA 437
    C,F--34965176(+) CCCCAG/AGCTAG 1 -- us2k11Minor allele frequency- A:0.06WA 118
    C--34965362(+) AAATCG/TGAGTC 1 -- us2k10--------
    C,F,A,H--34965522(-) accacA/Gcccgg 1 -- us2k17Minor allele frequency- G:0.48NS NA WA EA 484
    C,A--34965524(+) GGGCGT/CGGTGG 1 -- us2k15Minor allele frequency- C:0.13WA CSA NA EA 244
    C,A--34965572(+) CGGGCG/AGATCA 1 -- us2k1 tfbs32Minor allele frequency- A:0.33WA CSA 3
    --34965646(+) ACAAAA/GATTAG 1 -- us2k10--------
    C,F--34965703(+) GAGGCG/ATGACA 1 -- us2k16Minor allele frequency- A:0.16NA WA CSA EA 363
    C--34965760(+) CTGAGC/G/TGACAG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CHKB (51017378 - 51039884 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for CHKB (see all 14):    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv914559CNV Loss21882294
    nsv915495CNV Loss21882294
    nsv914561CNV Loss21882294
    dgv5062n71CNV Loss21882294
    dgv5068n71CNV Loss21882294
    nsv914525CNV Loss21882294
    nsv914543CNV Loss21882294
    nsv834239CNV Loss17160897
    dgv5066n71CNV Loss21882294
    nsv471224CNV Loss18288195

    Human Gene Mutation Database (HGMD): CHKB
    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing CHKB

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB, Sets of similar genes according to GenesLikeMe)
    About This Section

    OMIM gene information: 612395   
    OMIM disorders: 602541  
    Selected diseases for CHKB (see all 46):    
    About MalaCards
    spermatic cord torsion    japanese spotted fever    cytoplasmic body myopathy    fainting
    cardiac rupture    distal muscular dystrophy    adult dermatomyositis    proximal spinal muscular atrophy
    compartment syndrome    muscular dystrophy, congenital, megaconial type    chkb-related muscle diseases    acute myocardial infarction
    myositis    gas gangrene    creatine phosphokinase, elevated serum    pericardial effusion
    neuroleptic malignant syndrome    chondroblastoma    endometritis    myoblastoma

    1 inferred disease relationship from the University of Copenhagen DISEASES database for CHKB:
    Sleep disorder

    Find genes that share disorders with CHKB           About GenesLikeMe

    Selected Novoseek inferred disease relationships for CHKB gene (see all 97)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    rhabdomyolysis 84 82 19534642 (4), 20014178 (4), 1952045 (2), 14655521 (2) (see all 46)
    acute myocardial infarction 78.9 102 11253625 (3), 7666339 (3), 8164150 (2), 8937582 (2) (see all 79)
    creatine phosphokinase, elevated serum 78.6 4 9141928 (1), 16502425 (1), 11993531 (1), 11532557 (1)
    myopathy 76.3 60 15367725 (3), 19078624 (2), 17327290 (2), 19833260 (2) (see all 48)
    polymyositis 71.8 18 8480146 (2), 2088650 (2), 9745852 (1), 7914924 (1) (see all 13)
    myositis 71.7 30 7474450 (3), 8480146 (2), 17763431 (2), 11317279 (1) (see all 22)
    myocardial infarction 70.7 87 18328834 (3), 8557926 (3), 19050596 (2), 9115102 (2) (see all 61)
    muscular dystrophy duchenne 65.3 8 10825803 (2), 9829280 (1), 11269976 (1), 11532557 (1) (see all 7)
    infarct 64.1 94 16645412 (7), 19050596 (4), 15546288 (4), 9453514 (4) (see all 47)
    neuroleptic malignant syndrome 60.2 6 8101383 (1), 16453254 (1), 16145285 (1), 19952877 (1) (see all 6)

    Genetic Association Database (GAD): CHKB
    Human Genome Epidemiology (HuGE) Navigator: CHKB (7 documents)

    Export disorders for CHKB gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CHKB gene, integrated from 10 sources (see all 1090) (see top 10):
    (articles sorted by number of sources associating them with CHKB)

    1. Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? (PubMed id 20602615)1, 4 RuaA+o G....Wu A.H. (Pharmacogenomics 2010)
    2. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    3. Polymorphism located between CPT1B and CHKB, and HLA-DRB1*1501-DQB1*0602 haplotype confer susceptibility to CNS hypersomnias (essential hypersomnia). (PubMed id 19404393)1, 4 Miyagawa T....Tokunaga K. (PLoS ONE 2009)
    4. Physiogenomic comparison of edema and BMI in patients receiving rosiglitazone or pioglitazone. (PubMed id 18996102)1, 4 RuaA+o G....Hanks S. ( international journal of clinical chemistry 2009)
    5. Differential role of human choline kinase alpha and beta enzymes in lipid metabolism: implications in cancer onset and treatment. (PubMed id 19915674)1, 2 Gallego-Ortega D.... Lacal J.C. (PLoS ONE 2009)
    6. Variant between CPT1B and CHKB associated with susceptibility to narcolepsy. (PubMed id 18820697)1, 4 Miyagawa T....Tokunaga K. (Nat. Genet. 2008)
    7. A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (Genome Biol. 2004)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    10. Structure and function of choline kinase isoforms in mammalian cells. (PubMed id 15003397)1, 3 Aoyama C....Ishidate K. (Prog. Lipid Res. 2004)
    11. Novel expression of equivocal messages containing both regions of choline/ethanolamine kinase and muscle type carnitine palmitoyltransferase I. (PubMed id 10918069)1, 2 Yamazaki N.... Terada H. (J. Biol. Chem. 2000)
    12. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    13. Muscular dystrophy with large mitochondria associated with mutations in the CHKB gene in three British patients: extending the clinical and pathological phenotype. (PubMed id 23692895)1 Quinlivan R....Straub V. (Neuromuscul. Disord. 2013)
    14. Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-I+-acetylation features. (PubMed id 22223895)2 Bienvenut W.V....Giglione C. (amp 2012)
    15. TCRA, P2RY11, and CPT1B/CHKB associations in Chinese narcolepsy. (PubMed id 22177342)1 Han F....Mignot E. (Sleep Med. 2012)
    16. A congenital muscular dystrophy with mitochondrial structural abnormalities caused by defective de novo phosphatidylcholine biosynthesis. (PubMed id 21665002)1 Mitsuhashi S....Nishino I. (Am. J. Hum. Genet. 2011)
    17. Crystal structures of human choline kinase isoforms in complex with hemicholinium-3: single amino acid near the active site influences inhibitor sensitivity. (PubMed id 20299452)1 Hong B.S.... Park H.W. (J. Biol. Chem. 2010)
    18. Choline kinase and its function. (PubMed id 20651826)1 Wu G. and Vance D.E. (Biochem. Cell Biol. 2010)
    19. Distinct choline metabolic profiles are associated with differences in gene expression for basal-like and luminal-like breast cancer xenograft models. (PubMed id 20716336)1 Moestue S.A....Gribbestad I.S. (BMC Cancer 2010)
    20. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (Am. J. Hum. Genet. 2009)
    21. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    22. Phosphocholine as a biomarker of breast cancer: molecular and biochemical studies. (PubMed id 17236204)7 Eliyahu G....Degani H. (Int. J. Cancer 2007)
    23. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    24. A rostrocaudal muscular dystrophy caused by a defect in choline kinase beta, the first enzyme in phosphatidylcholine biosynthesis. (PubMed id 16371353)7 Sher R.B....Cox G.A. (J. Biol. Chem. 2006)
    25. An investigation into the human serum &quot;interactome&quot;. (PubMed id 15174051)1 Zhou M....Conrads T.P. (Electrophoresis 2004)
    26. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    27. Identification of novel transcribed sequences on human chromosome 22 by expressed sequence tag mapping. (PubMed id 11258795)1 Hirosawa M.... Ohara O. (DNA Res. 2001)
    28. Structure and characterization of the genes for murine choline/ethanolamine kinase isozymes alpha and beta. (PubMed id 10706593)1 Aoyama C....Ishidate K. (J. Lipid Res. 2000)
    29. The DNA sequence of human chromosome 22. (PubMed id 10591208)2 Dunham I.... Wright H. (Nature 1999)
    30. Complementary DNA sequence for a 42 kDa rat kidney choline/ethanolamine kinase. (PubMed id 9487136)1 Aoyama C....Ishidate K. (Biochim. Biophys. Acta 1998)
    31. Choline/ethanolamine kinase from mammalian tissues. (PubMed id 9370318)1 Ishidate K. (Biochim. Biophys. Acta 1997)
    32. Structural features of the gene encoding human muscle type carnitine palmitoyltransferase I. (PubMed id 9224698)3 Yamazaki N....Terada H. (FEBS Lett. 1997)
    33. Congenital Muscular Dystrophy Overview (PubMed id 20301468)1 Pagon R.A....Stephens K. (1993)
    34. The significance of creatine kinase in cardiac patients with acute limb ischaemia. (PubMed id 10596995)9 Brow T.D....Das S.K. (J Cardiovasc Surg (Torino) 1999)
    35. Serum creatine kinase elevation in a medical department. (PubMed id 11253625)9 Kodatsch I....StAPllberger C. (Acta Med. Austriaca 2001)
    36. Glucose, free fatty acid and ketone body metabolism in Duchenne muscular dystrophy. (PubMed id 2240459)9 Nishio H....Nakamura H. (amp 1990)
    37. Effect of newly proposed CK reference limits on neuromuscular diagnosis. (PubMed id 19260057)9 Nardin R.A....Tarulli A.W. (amp 2009)
    38. CK-MM autoantibodies: prevalence, immune complexes, and effect on CK clearance. (PubMed id 16810680)9 Warren G.L....Clarkson P.M. (amp 2006)
    39. Complexes of creatine kinase and immunoglobulins in serum identified by a nonimmune binding method. (PubMed id 1993321)9 Backer E.T....van Wermeskerken R.K. (Clin. Chem. 1991)
    40. Reduced myocardial creatine kinase flux in human myocardial infarction: an in vivo phosphorus magnetic resonance spectroscopy study. (PubMed id 19332463)9 Bottomley P.A....Weiss R.G. (Circulation 2009)
    41. Serum cardiac troponin T, but not troponin I, is elevated in idiopathic inflammatory myopathies. (PubMed id 19833747)9 Aggarwal R....Case J.P. (J. Rheumatol. 2009)
    42. Estimation of infarct size by single measurements of creatine kinase levels in patients with a first myocardial infarction. (PubMed id 16645412)9 Di Chiara A....Fioretti P.M. (J Cardiovasc Med (Hagerstown) 2006)
    43. Increased creatine kinase and spontaneous activity on electromyography, in amyotrophic lateral sclerosis. (PubMed id 12712806)9 Lima Carvalho M. (Electromyogr Clin Neurophysiol 2003)
    44. Short-term immobilization after eccentric exercise. Part II: creatine kinase and myoglobin. (PubMed id 12750585)9 Sayers S.P. and Clarkson P.M. (Med Sci Sports Exerc 2003)
    45. Creatine kinase as an indicator of sperm quality and maturity in men with oligospermia. (PubMed id 11549497)9 Hallak J....Agarwal A. (Urology 2001)
    46. Abnormal properties of creatine kinase in Alzheimer's disease brain: correlation of reduced enzyme activity and active site photolabeling with aberrant cytosol-membrane partitioning. (PubMed id 9555058)9 David S....Haley B.E. (Brain Res. Mol. Brain Res. 1998)
    47. Muscle toxicity with statins. (PubMed id 20014178)9 Hedenmalm K....Dahl M.L. (Pharmacoepidemiol Drug Saf 2010)
    48. The risk for significant creatine kinase elevation with statins. (PubMed id 20524720)9 Stolcpart R.S....Merenich J.A. (Am J Cardiovasc Drugs 2010)
    49. Creatine kinase monitoring in sport medicine. (PubMed id 17569697)9 Brancaccio P....Limongelli F.M. (Br. Med. Bull. 2007)
    50. Less calcemic Vitamin D analogs enhance creatine kinase specific activity and modulate responsiveness to gonadal steroids in the vasculature. (PubMed id 17029789)9 Somjen D....Stern N. (J. Steroid Biochem. Mol. Biol. 2006)
    51. Expression and carbonylation of creatine kinase in the quadriceps femoris muscles of patients with chronic obstructive pulmonary disease. (PubMed id 16166745)9 Barreiro E....Hussain S.N. (Am. J. Respir. Cell Mol. Biol. 2005)
    52. Serum creatine kinase levels in overt and subclinical hypothyroidism. (PubMed id 16392619)9 Hekimsoy Z. and Oktem I.K. (Endocr. Res. 2005)
    53. Low values of creatine kinase in systemic lupus erythematosus. Clinical significance in 300 patients. (PubMed id 12508777)9 Font J....Ingelmo M. (Clin. Exp. Rheumatol. 2002)
    54. Effects of zinc on creatine kinase: activity changes, conformational changes, and aggregation. (PubMed id 11233168)9 Tong X....Zhou H.M. (J. Protein Chem. 2000)
    55. Effect of therapeutic interventions on CK and CK MB serum activity kinetics during acute myocardial infarct. (PubMed id 9115102)9 Raos V....Straus B. (Acta Med Croatica 1997)
    56. [Increase of blood levels of creatine kinase following intramuscular injection]. (PubMed id 9064405)9 Montero PAcrez F.J....Torres Murillo J. (Med Clin (Barc) 1996)
    57. Reduced serum creatine kinase activity in inflammatory rheumatic diseases. (PubMed id 8882037)9 SanmartA- R....MuA+oz-Gomez J. (J. Rheumatol. 1996)
    58. Effect of cysteine modification on creatine kinase aggregation. (PubMed id 18548203)9 Zou H.C....Park Y.D. (Appl. Biochem. Biotechnol. 2009)
    59. Sertraline-induced rhabdomyolysis in an elderly patient with dementia and comorbidities. (PubMed id 19567656)9 Gareri P....De Sarro G. (Ann Pharmacother 2009)
    60. IL6 (-174) and TNFA (-308) promoter polymorphisms are associated with systemic creatine kinase response to eccentric exercise. (PubMed id 18758806)9 Yamin C....Amir R.E. (Eur. J. Appl. Physiol. 2008)
    61. Less-calcemic vitamin D analogs enhance creatine kinase specific activity and modulate responsiveness to gonadal steroids in rat skeletal tissues. (PubMed id 17392597)9 Somjen D....Kaye A.M. (J. Endocrinol. Invest. 2007)
    62. Serum cardiac markers response to biphasic and monophasic electrical cardioversion for supraventricular tachyarrhythmia--a randomised study. (PubMed id 16901614)9 Skulec R....Aschermann M. (Resuscitation 2006)
    63. Incidence of serum creatine kinase elevation and its relation to medications used after heart transplantation. (PubMed id 15659133)9 Hsu R.B....Chu S.H. (Clin Transplant 2005)
    64. Early peak creatine kinase activity is not always a marker of successful reperfusion with myocardial salvage in patients with reperfused anterior acute myocardial infarction. (PubMed id 11320363)9 Kosuge M....Umemura S. (Am. Heart J. 2001)
    65. Age-related variations of serum CK and CK MB response in females. (PubMed id 11098154)9 Arnett M.G....Schneider C.M. (Can J Appl Physiol 2000)
    66. [Pathogenesis of pulmonary thrombosis in Duchenne muscular dystrophy; a consideration from changes in serum CK and LDH levels]. (PubMed id 10825803)9 Nakayama T....Kawai M. (Rinsho Shinkeigaku 2000)
    67. Release kinetics of cardiac troponin I and cardiac troponin T in effluents from isolated perfused rabbit hearts after graded experimental myocardial contusion. (PubMed id 10498300)9 Bertinchant J.P....Dauzat M. (J Trauma 1999)
    68. Marked elevation of serum creatine kinase associated with olanzapine therapy. (PubMed id 10410183)9 Marcus E.L....Zislin J. (Ann Pharmacother 1999)
    69. Cytokeratin patterns of liver carcinomas induced by diethylnitrosamine in monkeys. (PubMed id 7540236)9 Lapis K....Thorgeirsson U.P. ( a journal of technical methods and pathology 1995)
    70. Creatine kinase alterations after acute malignant hyperthermia episodes and common surgical procedures. (PubMed id 7486044)9 Antognini J.F. (Anesth. Analg. 1995)
    71. Rapid diagnosis of coronary reperfusion by measurement of myoglobin level every 15 min in acute myocardial infarction. (PubMed id 8144762)9 Miyata M....Tahara M. (J. Am. Coll. Cardiol. 1994)
    72. Creatine kinase-MB mass concentration versus creatine kinase-B activity for the detection of acute myocardial infarction in patients with slightly elevated total creatine kinase activity in serum. (PubMed id 8120516)9 Hulting J....Wallinder H. (J. Intern. Med. 1994)
    73. Immunofluorescent analysis of creatine kinase in cultured astrocytes by conventional and confocal microscopy: a nuclear localization. (PubMed id 1282525)9 Manos P. and Edmond J. (J. Comp. Neurol. 1992)
    74. Creatine kinase and creatine kinase isoenzymes as a marker of uterine activity. (PubMed id 1418156)9 Satin A.J....Scott R.T. (Am J Perinatol 1992)
    75. CK-MM gene polymorphism does not influence the blood CK activity levels after exhaustive eccentric exercise. (PubMed id 20157874)9 Yamin C....Duarte J.A. (Int J Sports Med 2010)
    76. Comparative predictive value of infarct location, peak CK, and ejection fraction after primary PCI for ST elevation myocardial infarction. (PubMed id 19050596)9 Nienhuis M.B....van 't Hof A.W. (Coron. Artery Dis. 2009)
    77. Low creatine kinase is associated with a high population incidence of fainting. (PubMed id 19468786)9 Brewster L.M....Wieling W. (Clin. Auton. Res. 2009)
    78. The upper values of plasma creatine kinase of professional soccer players during the Brazilian National Championship. (PubMed id 18069060)9 Lazarim Macedo D.V. (J Sci Med Sport 2009)
    79. Admission creatine kinase as a prognostic marker in acute myocardial infarction. (PubMed id 20201171)9 Kazmi K.A....Iqbal M.P. (J Pak Med Assoc 2009)
    80. Blocking creatine kinase refolding by trace amounts of copper ions. (PubMed id 18255152)9 Feng S....Yan Y.B. (J. Inorg. Biochem. 2008)
    81. CK levels in unmedicated bipolar patients. (PubMed id 17628446)9 Segal M....Weizman A. (Eur Neuropsychopharmacol 2007)
    82. Application of serum CK and BUN determination in monitoring pre-competition training of badminton athletes. (PubMed id 17393126)9 Yang Y. (J. Huazhong Univ. Sci. Technol. Med. Sci. 2007)
    83. Compensation of type I and type II cytokeratin pools in lung cancer. (PubMed id 17161499)9 Kanaji N....Kubo A. (Lung Cancer 2007)
    84. Serum creatine kinase levels and renal function measures in exertional muscle damage. (PubMed id 16679975)9 Clarkson P.M....Thompson P.D. (Med Sci Sports Exerc 2006)
    85. ATP flux through creatine kinase in the normal, stressed, and failing human heart. (PubMed id 15647364)9 Weiss R.G....Bottomley P.A. (Proc. Natl. Acad. Sci. U.S.A. 2005)
    86. [Striated muscular injury and myocardiac injury caused by acute carbon monoxide poisoning]. (PubMed id 16405777)9 Wang H.T....Li Y.P. (Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2005)
    87. Preventing renal failure in patients with rhabdomyolysis: do bicarbonate and mannitol make a difference? (PubMed id 15211124)9 Brown C.V....Velmahos G.C. (J Trauma 2004)
    88. Indices of muscular damage in the perioperative period of peripheral revascularization procedures. (PubMed id 15702060)9 Olivei M.C....Guglielmotti E. (Minerva Anestesiol 2004)
    89. Creatine kinase and aspartate aminotransferase in cows as indicators for endometritis. (PubMed id 15214854)9 Sattler T. and FA1rll M. (J Vet Med A Physiol Pathol Clin Med 2004)
    90. Cytokeratin profiles of the thymus and thymomas: histogenetic correlations and proposal for a histological classification of thymomas. (PubMed id 10792481)9 Kuo T.t. (Histopathology 2000)
    91. Plasma creatine kinase responses of 18- to 30-yr-old African-American men to eccentric exercise. (PubMed id 10694119)9 Schwane J.A....Shepherd J.R. (Med Sci Sports Exerc 2000)
    92. Preconditioning the human myocardium by simulated ischemia: studies on the early and delayed protection. (PubMed id 10728354)9 Ghosh S....GaliA+anes M. (Cardiovasc. Res. 2000)
    93. Serum creatine kinase activity is not a reliable marker for muscle damage in conditions associated with low extracellular glutathione concentration. (PubMed id 9590365)9 Gunst J.J....Leroux-Roels G.G. (Clin. Chem. 1998)
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    389. Intermediate coronary revascularization using the Deltastream blood pump: results from an experimental study. (PubMed id 19241363)9 Litmathe J....Gams E. (Int J Artif Organs 2009)
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    391. Effects of eccentric treadmill exercise on inflammatory gene expression in human skeletal muscle. (PubMed id 19767811)9 Buford T.W....Willoughby D.S. (Appl Physiol Nutr Metab 2009)
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    396. Stereospecificity, substrate, and inhibitory properties of nucleoside diphosphate analogs for creatine and pyruvate kinases. (PubMed id 18433830)9 Wennefors C.K....Shaw B.R. (Bioorg. Chem. 2008)
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    402. The application of NMR spectroscopy for the study of heart failure. (PubMed id 18673182)9 ten Hove M. and Neubauer S. (Curr. Pharm. Des. 2008)
    403. The effects of contrast bathing and compression therapy on muscular performance. (PubMed id 18580411)9 French D.N....Wilkes G. (Med Sci Sports Exerc 2008)
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    406. Methylene blue increases contralateral testicular ischaemia-reperfusion injury after unilateral testicular torsion. (PubMed id 18047627)9 Inan M....Turan N. (amp 2008)
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    408. Serum markers of brain-cell damage and C-reactive protein are unaffected by electroconvulsive therapy. (PubMed id 17853285)9 Giltay E.J....Blansjaar B.A. (World J. Biol. Psychiatry 2008)
    409. Serum interferon-gamma-inducible protein 10 level was increased in myocardial infarction patients, and negatively correlated with infarct size. (PubMed id 17963704)9 Koten K....Ohe T. (Clin. Biochem. 2008)
    410. Inhibition of brain creatine kinase activity after renal ischemia is attenuated by N-acetylcysteine and deferoxamine administration. (PubMed id 18304734)9 Di-Pietro P.B....Streck E.L. (Neurosci. Lett. 2008)
    411. Acute renal failure due to rhabdomyolysis in a child with McArdle disease. (PubMed id 17899190)9 DelibaA9 A....Oner A. (Eur. J. Pediatr. 2008)
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    413. Does pregnancy-associated plasma protein A have a role in allergic rhinitis? (PubMed id 18588751)9 GA1AslA1 E....Egeli E. (Am J Rhinol 2008)
    414. Blood parameters in adults with intellectual disability at rest and after endurance exercise. (PubMed id 19089748)9 Carmeli E....Merrick J. (Res Sports Med 2008)
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    417. Ventricle-specific metabolic differences in the newborn piglet myocardium in vivo and during arrested global ischemia. (PubMed id 18043511)9 Quaglietta D....Wittnich C. (Pediatr. Res. 2008)
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    420. Utility of cardiac biomarkers in predicting infarct size, left ventricular function, and clinical outcome after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction. (PubMed id 19463339)9 Chia S....Jang I.K. (JACC Cardiovasc Interv 2008)
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    422. Multiscale and modular analysis of cardiac energy metabolism: repairing the broken interfaces of isolated system components. (PubMed id 18375588)9 Van Beek J.H. (Ann. N. Y. Acad. Sci. 2008)
    423. Effects of allicin supplementation on plasma markers of exercise-induced muscle damage, IL-6 and antioxidant capacity. (PubMed id 18305954)9 Su Q.S....Zhang H. (Eur. J. Appl. Physiol. 2008)
    424. Cerebrospinal creatinine kinase level in children with meningitis. (PubMed id 18501707)9 Tamimi W....Alharbi K.K. (Clin. Biochem. 2008)
    425. Acute kidney injury due to rhabdomyolysis-associated gangrenous myositis. (PubMed id 19260387)9 Daher E.F....LibA^rio A.B. (Acta Biomed 2008)
    426. Changes in clinical enzyme activity and bile acid levels in psittacine birds with altered liver function and disease. (PubMed id 18543598)9 Cray C....Arheart K.L. (J. Avian Med. Surg. 2008)
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    428. C2C12 myoblastoma cell differentiation and proliferation is stimulated by androgens and associated with a modulation of myostatin and Pax7 expression. (PubMed id 18434429)9 Diel P....Schwarz J.P. (J. Mol. Endocrinol. 2008)
    429. The creatine kinase response to eccentric exercise with atorvastatin 10 mg or 80 mg. (PubMed id 18261731)9 Kearns A.K....Thompson P.D. (Atherosclerosis 2008)
    430. Evolution of serum biochemical indicators in anorexia nervosa patients: a 1-year follow-up study. (PubMed id 18184391)9 Nova E....Marcos A. (J Hum Nutr Diet 2008)
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    432. Release of cardiac bio-markers during high mechanical index contrast-enhanced echocardiography in humans. (PubMed id 17409107)9 Vancraeynest D....Vanoverschelde J.L. (Eur. Heart J. 2007)
    433. Plasma creatine kinase indicates major amputation or limb preservation in acute lower limb ischemia. (PubMed id 17398384)9 Currie I.S....Chalmers R.T. (J. Vasc. Surg. 2007)
    434. Increased serum creatine kinase is a reliable marker for acute transplanted heart rejection diagnosis in rats. (PubMed id 17239027)9 BaA+A^n-Maneus la Ossa P.P. (Transpl. Int. 2007)
    435. MR spectroscopy in heart failure--clinical and experimental findings. (PubMed id 17333358)9 Ten Hove M. and Neubauer S. (Heart Fail Rev 2007)
    436. Myoglobin plasma level related to muscle mass and fiber composition: a clinical marker of muscle wasting? (PubMed id 17605115)9 Weber M.A....Hildebrandt W. (J. Mol. Med. 2007)
    437. Comparative cytokeratin distribution patterns in cholesteatoma epithelium. (PubMed id 17128409)9 Olszewska E. and Sudhoff H. (Histol. Histopathol. 2007)
    438. Neurogenic pulmonary oedema misdiagnosed as acute myocardial infarction in a comatose patient. (PubMed id 17767340)9 Seow V.K....Chong C.F. (Ann. Acad. Med. Singap. 2007)
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    443. Cardiac troponin I concentrations in people presenting with diabetic ketoacidosis. (PubMed id 17594788)9 Geddes J....Fisher B.M. (Ann. Clin. Biochem. 2007)
    444. Rituximab for refractory polymyositis: an open-label prospective study. (PubMed id 17722224)9 Mok C.C....To C.H. (J. Rheumatol. 2007)
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    446. Metabolic and clinical traits in horses undergoing feed deprivation for elective orthopaedic surgery. (PubMed id 17416136)9 Reinprecht B....Zentek J. (Berl. Munch. Tierarztl. Wochenschr. 2007)
    447. Dynamics and source of endothelin-1 and interleukin-6 following coronary reperfusion in patients with acute myocardial infarction. (PubMed id 17507790)9 Imaizumi T....Takano T. (J Nippon Med Sch 2007)
    448. 'Postconditioning' the human heart: multiple balloon inflations during primary angioplasty may confer cardioprotection. (PubMed id 17235447)9 Darling C.E....Przyklenk K. (Basic Res. Cardiol. 2007)
    449. Statin and statin-fibrate use was significantly associated with increased myositis risk in a managed care population. (PubMed id 17606177)9 McClure D.L....Hokanson J.E. (J Clin Epidemiol 2007)
    450. CK-MM and ACE genotypes and physiological prediction of the creatine kinase response to exercise. (PubMed id 17478608)9 Heled Y....Deuster P.A. (J. Appl. Physiol. 2007)
    451. Ischaemia modified albumin in radiofrequency catheter ablation. (PubMed id 17213337)9 Sbarouni E....Kremastinos D.T. (Europace 2007)
    452. In vitro effect of quinolinic acid on energy metabolism in brain of young rats. (PubMed id 17126438)9 Schuck P.F....Wajner M. (Neurosci. Res. 2007)
    453. Troponin-I concentration 72 h after myocardial infarction correlates with infarct size and presence of microvascular obstruction. (PubMed id 17540686)9 Younger J.F....Greenwood J.P. (Heart 2007)
    454. Blood biochemistry reveals malnutrition in black-necked swans (Cygnus melanocoryphus) living in a conservation priority area. (PubMed id 17158079)9 Artacho P....Nespolo R.F. (amp 2007)
    455. Early evolution of the creatine kinase gene family and the capacity for creatine biosynthesis and membrane transport. (PubMed id 18652070)9 Ellington W.R. and Suzuki T. (Subcell. Biochem. 2007)
    456. A new model for the study of the abdominal compartment syndrome in rats. (PubMed id 17254610)9 Meier C....Menger M.D. (J. Surg. Res. 2007)
    457. Long-term aerobic exercise protects the heart against ischemia/reperfusion injury via PI3 kinase-dependent and Akt-mediated mechanism. (PubMed id 17505785)9 Zhang K.R....Gao F. (Apoptosis 2007)
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    459. The effect of alpha-Tocopherol supplementation on training-induced elevation of S100B protein in sera of basketball players. (PubMed id 17532314)9 Schulpis K.H....Tsakiris S. (Clin. Biochem. 2007)
    460. Advanced-glycation end products (AGEs) derived from glycated albumin suppress early beta1-adrenergic preconditioning. (PubMed id 17227443)9 Robinet A....Millart H. (amp 2007)
    461. Limited effects of high-dose intravenous immunoglobulin (IVIG) treatment on molecular expression in muscle tissue of patients with inflammatory myopathies. (PubMed id 17277004)9 Barbasso Helmers S....Lundberg I.E. (Ann. Rheum. Dis. 2007)
    462. The generation of the oxidized form of creatine kinase is a negative regulation on muscle creatine kinase. (PubMed id 17303563)9 Zhao T.J....Zhou H.M. (J. Biol. Chem. 2007)
    463. An unusual case of congenital muscular dystrophy with normal serum CK level, external ophtalmoplegia, and white matter changes on brain MRI. (PubMed id 17395506)9 Vondracek P....Tajsharghi H. (Eur. J. Paediatr. Neurol. 2007)
    464. Acute myopathy in a patient with oesophageal stricture. (PubMed id 17965038)9 Possamai L. and Waring W.S. (Age Ageing 2007)
    465. A novel FKRP gene mutation in a Taiwanese patient with limb-girdle muscular dystrophy 2I. (PubMed id 17055682)9 Lin Y.C....Jong Y.J. (amp 2007)
    466. Decreased blood oxidative stress after repeated muscle-damaging exercise. (PubMed id 17596775)9 Nikolaidis M.G....Jamurtas A.Z. (Med Sci Sports Exerc 2007)
    467. Typhoid myopathy or typhoid hepatitis: a matter of debate. (PubMed id 18087083)9 Mirsadraee M....Roknee F. (Indian J Med Microbiol 2007)
    468. The creatine kinase phosphotransfer network: thermodynamic and kinetic considerations, the impact of the mitochondrial outer membrane and modelling approaches. (PubMed id 18652071)9 Saks V....Vendelin M. (Subcell. Biochem. 2007)
    469. Baseline serum levels of cardiac biomarkers in patients with stable coronary artery disease. (PubMed id 17701751)9 Karacalioglu O....Ozguven M. (Biomarkers 2007)
    470. Effects of the single point genetic mutation D54G on muscle creatine kinase activity, structure and stability. (PubMed id 17030001)9 Feng S....Yan Y.B. (amp 2007)
    471. Markers of muscle ischemia, necrosis, and inflammation following uterine artery embolization in the treatment of symptomatic uterine fibroids. (PubMed id 17346524)9 Banu N.S....Manyonda I.T. (Am. J. Obstet. Gynecol. 2007)
    472. Colchicine prescribing and safety monitoring in patients with gout. (PubMed id 18264188)9 Ly J....Dalbeth N. (N. Z. Med. J. 2007)
    473. Monomeric creatine kinase aggregation and sodium dodecyl sulfate-cyclodextrin assisted refolding. (PubMed id 17206851)9 Zou H.C....Park Y.D. (amp 2007)
    474. Gabapentin-induced severe myopathy. (PubMed id 17565043)9 Tuccori M....Del Tacca M. (Ann Pharmacother 2007)
    475. Mycophenolate mofetil treatment in resistant myositis. (PubMed id 17003173)9 Pisoni C.N....D'Cruz D.P. (Rheumatology (Oxford) 2007)
    476. A novel compound heterozygous dysferlin mutation in Miyoshi myopathy siblings responding to dantrolene. (PubMed id 17868276)9 Hattori H....Suzuki N. (Eur. J. Neurol. 2007)
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    478. Antioxidants did not prevent muscle damage in response to an ultramarathon run. (PubMed id 16394956)9 Mastaloudis A....Widrick J.J. (Med Sci Sports Exerc 2006)
    479. Insulin resistance increases PAI-1 in the heart. (PubMed id 16750510)9 Sobel B.E....Pratley R.E. (Biochem. Biophys. Res. Commun. 2006)
    480. Rhabdomyolysis and acute renal failure following arthroscopic knee surgery in a college football player taking creatine supplements. (PubMed id 16509464)9 Sheth N.P....Berns J.S. (Clin. Nephrol. 2006)
    481. Effect of age on metabolic fatigue and on indirect symptoms of skeletal muscle damage after stretch-shortening exercise. (PubMed id 16998448)9 Skurvydas A....Mamkus G. (J Sports Med Phys Fitness 2006)
    482. Presymptomatic neuromuscular disorders disclosed following statin treatment. (PubMed id 16864763)9 Tsivgoulis G....Manta P. (Arch. Intern. Med. 2006)
    483. Cytokeratin expression in pseudoepitheliomatous hyperplasia of oral paracoccidioidomycosis. (PubMed id 16882606)9 Kaminagakura E....Scully C. (Med. Mycol. 2006)
    484. Macroenzyme creatine kinase (CK) type 2 in HIV-infected patients is significantly associated with TDF and consists of ubiquitous mitochondrial CK. (PubMed id 17302377)9 Schmid H....Goebel F.D. (Antivir. Ther. (Lond.) 2006)
    485. Massive creatine kinase elevations with quetiapine: report of two cases. (PubMed id 16453254)9 Klein J.P....Jockers-ScherA1bl M.C. (Pharmacopsychiatry 2006)
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    487. Effect of high dose vitamin C supplementation on muscle soreness, damage, function, and oxidative stress to eccentric exercise. (PubMed id 16948483)9 Bryer S.C. and Goldfarb A.H. (Int J Sport Nutr Exerc Metab 2006)
    488. Serum creatine kinase activity varies with ovulatory status in regularly exercising, premenopausal women. (PubMed id 16514242)9 Thompson H.S....De Souza M.J. (Horm. Res. 2006)
    489. Salivary enzymes and periodontal disease. (PubMed id 16505786)9 Todorovic T....Knezevic M. (Med Oral Patol Oral Cir Bucal 2006)
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    491. Rosuvastatin 5 and 10 mg/d: a pilot study of the effects in hypercholesterolemic adults unable to tolerate other statins and reach LDL cholesterol goals with nonstatin lipid-lowering therapies. (PubMed id 16860175)9 Glueck C.J....Wang P. (Clin Ther 2006)
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    493. Exertional Rhabdomyolysis during a 246-km continuous running race. (PubMed id 16775544)9 Skenderi K.P....Matalas A.L. (Med Sci Sports Exerc 2006)
    494. Relationship between the mismatch of 123I-BMIPP and 201Tl myocardial single-photon emission computed tomography and autonomic nervous system activity in patients with acute myocardial infarction. (PubMed id 16607047)9 Yamanaka H....Takano T. (Int Heart J 2006)
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    496. Raised troponin T in inclusion body myositis is common and serum levels are persistent over time. (PubMed id 16920359)9 Lindberg C....Oldfors A. (Neuromuscul. Disord. 2006)
    497. Metallothionein-3 is a component of a multiprotein complex in the mouse brain. (PubMed id 17018872)9 El Ghazi I....Armitage I.M. (Exp. Biol. Med. (Maywood) 2006)
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    501. Acute heroin-related neuropathy. (PubMed id 17117938)9 Dabby R....Watemberg N. (J. Peripher. Nerv. Syst. 2006)
    502. Muscular damage and intravascular haemolysis during an 18 hour subterranean exploration in a cave of 700 m depth. (PubMed id 16505080)9 Stenner E....Bussani A. (Br J Sports Med 2006)
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    504. Immunohistochemical study of porcine nephroblastoma. (PubMed id 16540114)9 Grieco V....Scanziani E. (J. Comp. Pathol. 2006)
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    506. Creatine and antioxidant treatment prevent the inhibition of creatine kinase activity and the morphological alterations of C6 glioma cells induced by the branched-chain alpha-keto acids accumulating in maple syrup urine disease. (PubMed id 16633902)9 Funchal C....Wajner M. (Cell. Mol. Neurobiol. 2006)
    507. An adolescent girl with Meyer-Betz syndrome. (PubMed id 16328090)9 Kasap B....Kavukcu S. (Clin. Rheumatol. 2006)
    508. Mammary NOS-type sarcoma with CD10 expression: a rare entity with features of myoepithelial differentiation. (PubMed id 16625090)9 Leibl S. and Moinfar F. (Am. J. Surg. Pathol. 2006)
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    510. The diagnostic value of cytokeratins and carcinoembryonic antigen immunostaining in differentiating hepatocellular carcinomas from intrahepatic cholangiocarcinomas. (PubMed id 16680226)9 Stroescu C....Popescu I. (J Gastrointestin Liver Dis 2006)
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    512. Sodium barbital is a slow reversible inactivator of rabbit-muscle creatine kinase. (PubMed id 16609694)9 Shi F....Wu P. (Biochem. Cell Biol. 2006)
    513. Differential myolysis of myocardium and skeletal muscle in hamsters with dilated cardiomyopathy: beneficial protective effect of diltiazem. (PubMed id 17062977)9 Kato Y....Yokota M. (Circ. J. 2006)
    514. Prognostic implications of creatine kinase elevation after primary percutaneous coronary intervention for acute myocardial infarction. (PubMed id 16516077)9 Halkin A....Mehran R. (J. Am. Coll. Cardiol. 2006)
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    516. Concerning the mechanism of pexelizumab's benefit in acute myocardial infarction. (PubMed id 16569534)9 Armstrong P.W....Granger C.B. (Am. Heart J. 2006)
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    519. Comparison of systemic cytokine responses after a long distance triathlon and a 100-km run: relationship to metabolic and inflammatory processes. (PubMed id 16840030)9 Gomez-Merino D....Chennaoui M. (Eur. Cytokine Netw. 2006)
    520. Comparison between risperidone, olanzapine, and clozapine in the management of chronic schizophrenia: a naturalistic prospective 12-week observational study. (PubMed id 16783815)9 Strous R.D....Spivak B. (Hum Psychopharmacol 2006)
    521. Neuroleptic malignant syndrome with delayed onset of fever following risperidone administration. (PubMed id 17119106)9 Norris B....Seale J.P. (Ann Pharmacother 2006)
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    523. Cell-free plasma DNA as a novel marker of aseptic inflammation severity related to exercise overtraining. (PubMed id 16840584)9 Fatouros I.G....Papassotiriou I. (Clin. Chem. 2006)
    524. Neurological manifestations of dengue virus infection. (PubMed id 16524594)9 Misra U.K....Dhole T.N. (J. Neurol. Sci. 2006)
    525. Capture of monomeric refolding intermediate of human muscle creatine kinase. (PubMed id 16373479)9 Li S....Zhou H.M. (Protein Sci. 2006)
    526. Improved detection of acute myocardial infarction using a diagnostic algorithm based on calculated epicardial potentials. (PubMed id 16368156)9 Owens C....Adgey J. (Int. J. Cardiol. 2006)
    527. Heterogeneity of Escherichia coli-expressed human muscle creatine kinase. (PubMed id 16801217)9 Wang P.F....McLeish M.J. (IUBMB Life 2006)
    528. [Differentiation of acute coronary syndrome and ulcerative colitis as causes of elevated macro creatine kinase in a patient with effort angina pectoris: a case report]. (PubMed id 17136824)9 Yokoo T....Koike A. (J Cardiol 2006)
    529. Influence of hemolysis on routine clinical chemistry testing. (PubMed id 16519604)9 Lippi G....Guidi G.C. (Clin. Chem. Lab. Med. 2006)
    530. Simvastatin-amiodarone interaction resulting in rhabdomyolysis, azotemia, and possible hepatotoxicity. (PubMed id 16537817)9 Ricaurte B....Zabriskie D. (Ann Pharmacother 2006)
    531. Responses of old men to repeated bouts of eccentric exercise of the elbow flexors in comparison with young men. (PubMed id 16767435)9 Lavender A.P. and Nosaka K. (Eur. J. Appl. Physiol. 2006)
    532. [Early marker of myocardial injury of the ischemia-reperfused heart in dogs and during operations with artificial circulation in humans]. (PubMed id 16958209)9 Sahach V.F....Knyshev H.V. (Fiziol Zh 2006)
    533. High plasma creatine kinase: review of the literature and proposal for a diagnostic algorithm. (PubMed id 17122938)9 Morandi L....Citterio A. (Neurol. Sci. 2006)
    534. [The investigation of ischemic myocardial damage in patients with carbon monoxide poisoning]. (PubMed id 16140649)9 Aslan S....Katirci Y. (Anadolu Kardiyol Derg 2005)
    535. Isotretinoin therapy induces DNA oxidative damage. (PubMed id 16232082)9 Georgala S....Schulpis K.H. (Clin. Chem. Lab. Med. 2005)
    536. Effect of short-acting inhaler beta2-agonists on serum cardiac troponin in wheezy infant. (PubMed id 16541973)9 TaA9ar M.A....Dallar Y. (Allergy Asthma Proc 2005)
    537. The most common mutation in FKRP causing limb girdle muscular dystrophy type 2I (LGMD2I) may have occurred only once and is present in Hutterites and other populations. (PubMed id 15580560)9 Frosk P....Wrogemann K. (Hum. Mutat. 2005)
    538. Prognostic significance of time-delay to peak creatine kinase after direct percutaneous coronary intervention in acute myocardial infarction patients. (PubMed id 16272768)9 Katayama T....Yano K. (Int Heart J 2005)
    539. Metaplastic breast carcinomas: are they of myoepithelial differentiation?: immunohistochemical profile of the sarcomatoid subtype using novel myoepithelial markers. (PubMed id 15725803)9 Leibl S....Moinfar F. (Am. J. Surg. Pathol. 2005)
    540. Denaturant sensitive regions in creatine kinase identified by hydrogen/deuterium exchange. (PubMed id 15880663)9 Mazon H....Vial C. (Rapid Commun. Mass Spectrom. 2005)
    541. Creatine kinase, a magnetic resonance-detectable marker gene for quantification of liver-directed gene transfer. (PubMed id 16390274)9 Li Z....Zhou R. (Hum. Gene Ther. 2005)
    542. Effect of macro-creatine kinase and increased creatine kinase BB on the rapid diagnosis of patients with suspected acute myocardial infarction in the emergency department. (PubMed id 16173202)9 Serdar M.A....Kutluay T. (Mil Med 2005)
    543. Physiogenomic analysis links serum creatine kinase activities during statin therapy to vascular smooth muscle homeostasis. (PubMed id 16296949)9 RuaA+o G....Wu A.H. (Pharmacogenomics 2005)
    544. The prevalence of false-positive cardiac troponin I in ED patients with rhabdomyolysis. (PubMed id 16291441)9 Li S.F....Tillem E. (Am J Emerg Med 2005)
    545. Clinical factors associated with persistent pericardial effusion after successful primary coronary angioplasty. (PubMed id 16100170)9 Sugiura T....Iwasaka T. (Chest 2005)
    546. Biochemical diagnosis of myocardial infarction evolves towards ESC/ACC consensus: experiences from the Nordic countries. (PubMed id 16146978)9 HjortshA...Ravkilde J. (Scand. Cardiovasc. J. 2005)
    547. Exercise-induced muscle damage, plasma cytokines, and markers of neutrophil activation. (PubMed id 15870626)9 Peake J.M....Coombes J.S. (Med Sci Sports Exerc 2005)
    548. [Analysis of misdiagnosis in 33 cases of aortic dissection]. (PubMed id 16174592)9 Liang Z.T....Zhang B. (Di Yi Jun Yi Da Xue Xue Bao 2005)
    549. Evaluation of H-FABP as a marker of ongoing myocardial damage using hGH transgenic mice. (PubMed id 16026778)9 Naraoka H....Tojo H. ( international journal of clinical chemistry 2005)
    550. Attenuation of protective effect against eccentric exercise-induced muscle damage. (PubMed id 16293902)9 Nosaka K....Sacco P. (Can J Appl Physiol 2005)
    551. Clinical significance of von Willebrand factor in patients with adult dermatomyositis. (PubMed id 15565394)9 Komiya T....Yoshikawa J. (Clin. Rheumatol. 2005)
    552. Impact of intraoperative myocardial cellular damage on early hemodynamics after off-pump versus on-pump coronary artery bypass surgery. (PubMed id 15946923)9 Thielmann M....Jakob H. (Eur. J. Med. Res. 2005)
    553. Origin and properties of cytoplasmic and mitochondrial isoforms of taurocyamine kinase. (PubMed id 16008553)9 Uda K....Suzuki T. (FEBS J. 2005)
    554. Comparison between leg and arm eccentric exercises of the same relative intensity on indices of muscle damage. (PubMed id 16007451)9 Jamurtas A.Z....Nosaka K. (Eur. J. Appl. Physiol. 2005)
    555. Short-term and long-term in vivo exposure to an ephedra- and caffeine-containing metabolic nutrition system does not induce cardiotoxicity in B6C3F1 mice. (PubMed id 15895207)9 Ray S....Stohs S. (Arch. Toxicol. 2005)
    556. High serum erythropoietin level is associated with smaller infarct size in patients with acute myocardial infarction who undergo successful primary percutaneous coronary intervention. (PubMed id 15862410)9 Namiuchi S....Shirato K. (J. Am. Coll. Cardiol. 2005)
    557. [Serum creatine kinase activity in dogs and cats with metabolic diseases]. (PubMed id 16240913)9 Neumann S. (DTW. Dtsch. Tierarztl. Wochenschr. 2005)
    558. Effects of methylprednisolone and a biocompatible copolymer circuit on blood activation during cardiopulmonary bypass. (PubMed id 15680854)9 Rubens F.D....Mesana T. (Ann. Thorac. Surg. 2005)
    559. Body temperature - a marker of infarct size in the era of early reperfusion. (PubMed id 15785024)9 Ben-Dor I....Hasdai D. (Cardiology 2005)
    560. Negative myoglobin staining in hemiplegic muscle of acute stroke patients predicts functional recovery. (PubMed id 16141747)9 Sato Y....Satoh K. (amp 2005)
    561. [Quantitative analysis of serum troponin I and myoglobin in patients with acute myocardial infarction]. (PubMed id 15897132)9 Xiao H.G....Lin Y.P. (Di Yi Jun Yi Da Xue Xue Bao 2005)
    562. Reduced plasma levels of NGF and BDNF in patients with acute coronary syndromes. (PubMed id 15939120)9 Manni L....Aloe L. (Int. J. Cardiol. 2005)
    563. Changes of single fiber electromyography in patients with inflammatory myopathies. (PubMed id 15844301)9 Jian F....Du H. (Chin. Med. Sci. J. 2005)
    564. Compartmentation of energy metabolism in atrial myocardium of patients undergoing cardiac surgery. (PubMed id 15792353)9 Seppet E....Seppet E.K. (Mol. Cell. Biochem. 2005)
    565. Indications for angiography subsequent to coronary artery bypass grafting. (PubMed id 15976792)9 Alter P....Moosdorf R. (Am. Heart J. 2005)
    566. Differential association between statin exposure and elevated levels of creatine kinase. (PubMed id 16160000)9 Chan J....Levin E. (Ann Pharmacother 2005)
    567. [Protective effect of reduced glutathione on multiple organ function in patient with acute pancreatitis]. (PubMed id 16297323)9 Huang Z.W....Wang W. (Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 2005)
    568. Cardiac involvement in malignant syndrome in Parkinson's disease. (PubMed id 16145285)9 Sato Y....Satoh K. (Eur. Neurol. 2005)
    569. Distribution of cytokeratins and vimentin in adult renal neoplasms and normal renal tissue: potential utility of a cytokeratin antibody panel in the differential diagnosis of renal tumors. (PubMed id 15897741)9 Skinnider B.F....Amin M.B. (Am. J. Surg. Pathol. 2005)
    570. Effect of 6 months' training on the reactive oxygen species production capacity of neutrophils and serum opsonic activity in judoists. (PubMed id 15586397)9 Miura M....Sugawara K. (Luminescence 2005)
    571. [Protective effects of ulinastatin against multiple organic damage after severe burn injury: experimental and clinic studies]. (PubMed id 16324360)9 Hu X.H....Sun Y.H. (Zhonghua Yi Xue Za Zhi 2005)
    572. Dual-isotope myocardial SPECT in patients with redefined myocardial infarction. (PubMed id 16168815)9 Fukushima M....Takano T. (Int. J. Cardiol. 2005)
    573. The effect of cardiac troponin testing on clinical care in a veterans population: a randomized controlled trial. (PubMed id 16050851)9 Berkwits M....Kimmel S.E. (J Gen Intern Med 2005)
    574. [Effect of temperature of fluid infusion on diamine oxidase, MB isoenzyme of creatine kinase, creatine-kinase and lactate dehydrogenase in hemorrhagic shock rabbits]. (PubMed id 15636711)9 Liu Y.C....Su R. (Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 2005)
    575. Enzymatic examination of potential interaction between statins or fibrates and consumed Tricholoma equestre. (PubMed id 16225097)9 Chodorowski Z....Hajduk A. (Prz. Lek. 2005)
    576. Treatment of antisynthetase-associated interstitial lung disease with tacrolimus. (PubMed id 16052580)9 Wilkes M.R....Oddis C.V. (Arthritis Rheum. 2005)
    577. [Myopathies under therapy with lipid-lowering agents]. (PubMed id 15609055)9 KAPller H....Hartung H.P. (Nervenarzt 2005)
    578. Impact of the revised criteria for acute myocardial infarction using cardiac troponins in a Japanese population with acute coronary syndromes. (PubMed id 15988101)9 Yamamoto T....Takano T. (Circ. J. 2005)
    579. Elevated creatine kinase activity in primary hepatocellular carcinoma. (PubMed id 15748292)9 Meffert G....Wyss M. (BMC Gastroenterol 2005)
    580. ACTN3 and MLCK genotype associations with exertional muscle damage. (PubMed id 15817725)9 Clarkson P.M....Devaney J.M. (J. Appl. Physiol. 2005)
    581. Serum creatine kinase response to exercise during dexamethasone-induced insulin resistance in Quarter Horses with polysaccharide storage myopathy. (PubMed id 16273902)9 Firshman A.M....Seaquist E.R. (Am. J. Vet. Res. 2005)
    582. The electromyographic features of acute rhabdomyolysis. (PubMed id 19078759)9 Al-Shekhlee A....Katirji B. (J Clin Neuromuscul Dis 2005)
    583. The creatine kinase system in human skin: protective effects of creatine against oxidative and UV damage in vitro and in vivo. (PubMed id 15675966)9 Lenz H....Blatt T. (J. Invest. Dermatol. 2005)
    584. Laparoscopic renal surgery and the risk of rhabdomyolysis: diagnosis and treatment. (PubMed id 16194704)9 Reisiger K.E....Clayman R.V. (Urology 2005)
    585. Qualitative troponin I estimation in the diagnosis of acute coronary syndromes in three rural hospitals. (PubMed id 16356383)9 Hindle H.R. and Hindle S.K. (Can J Rural Med 2005)
    586. [Allogeneic umbilical cord blood stem cell transplantation in Duchenne muscular dystrophy]. (PubMed id 15949330)9 Zhang C....Liu Y. (Zhonghua Yi Xue Za Zhi 2005)
    587. The effect of creatine supplementation upon inflammatory and muscle soreness markers after a 30km race. (PubMed id 15306159)9 Santos R.V....Costa Rosa L.F. (Life Sci. 2004)
    588. Subclinical Becker's muscular dystrophy presenting with severe heart failure. (PubMed id 15098601)9 Yokota R....Hattori R. (Intern. Med. 2004)
    589. [Comparison of serum biochemical features between SARS and other viral pneumonias]. (PubMed id 15535901)9 Song S.Z....Tian Y.P. (Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 2004)
    590. Prognostic significance of the long pentraxin PTX3 in acute myocardial infarction. (PubMed id 15477419)9 Latini R....Mantovani A. (Circulation 2004)
    591. Changes in inflammatory mediators following eccentric exercise of the elbow flexors. (PubMed id 15633588)9 Hirose L....Suzuki K. (Exerc Immunol Rev 2004)
    592. Relationship between size of myocardial infarctions assessed by delayed contrast-enhanced MRI after primary PCI, biochemical markers, and time to intervention. (PubMed id 15546288)9 Haase J....Sommer T. (J Interv Cardiol 2004)
    593. Factors determining the oxygen consumption rate (VO2) on-kinetics in skeletal muscles. (PubMed id 14744260)9 Korzeniewski B. and Zoladz J.A. (Biochem. J. 2004)
    594. 15d-prostaglandin J2 reduces multiple organ failure caused by wall-fragment of Gram-positive and Gram-negative bacteria. (PubMed id 15364008)9 Dugo L....Thiemermann C. (Eur. J. Pharmacol. 2004)
    595. Quantitative assessment of MRI T2 relaxation time of thigh muscles in juvenile dermatomyositis. (PubMed id 14983103)9 Maillard S.M....Murray K.J. (Rheumatology (Oxford) 2004)
    596. Elevated cardiac troponin T in hemodialysis patients receiving more intravenous iron sucrose. (PubMed id 15600258)9 Guz G....Sindel S. (Ren Fail 2004)
    597. Severe acute respiratory syndrome: clinical and laboratory manifestations. (PubMed id 18458712)9 Lam C.W....Wong C.K. (Clin Biochem Rev 2004)
    598. Inhibition of mitochondrial creatine kinase activity from rat cerebral cortex by methylmalonic acid. (PubMed id 15234108)9 Schuck P.F....Wajner M. (Neurochem. Int. 2004)
    599. Reference intervals for eight enzymes in blood of adult females and males measured in accordance with the International Federation of Clinical Chemistry reference system at 37 degrees C: part of the Nordic Reference Interval Project. (PubMed id 15223701)9 StrA...Urdal P. (Scand. J. Clin. Lab. Invest. 2004)
    600. Role of amino acid residues on the GS region of Stichopus arginine kinase and Danio creatine kinase. (PubMed id 15115182)9 Uda K. and Suzuki T. (Protein J. 2004)
    601. Pathophysiology, prognostic significance and clinical utility of B-type natriuretic peptide in acute coronary syndromes. (PubMed id 15256312)9 Wiviott S.D....Morrow D.A. ( international journal of clinical chemistry 2004)
    602. [Stem cell mobilization after coronary artery bypass grafting]. (PubMed id 15253141)9 Gaspardone A....Chiariello L. (Ital Heart J Suppl 2004)
    603. Different effects of exercise tests on the antioxidant enzyme activities in lymphocytes and neutrophils. (PubMed id 15302083)9 Tauler P....Pons A. (J. Nutr. Biochem. 2004)
    604. Biochemical markers of myocardial damage after radiofrequency ablation. (PubMed id 15226782)9 Bednarek J....Lelakowski J. (Kardiol Pol 2004)
    605. Cornification (keratinization) in Basal cell carcinoma: a histopathological and immunohistochemical study of 16 cases. (PubMed id 15492437)9 Misago N....Narisawa Y. (J. Dermatol. 2004)
    606. Troponin T: how high is high? Relationship and differences between serum cardiac markers according to level of creatine kinase and type of myocardial infarction. (PubMed id 15466999)9 Williams S.G....Currie P. (Postgrad Med J 2004)
    607. Cytokeratin expression in central mucoepidermoid carcinoma and glandular odontogenic cyst. (PubMed id 15006629)9 Pires F.R....Kowalski L.P. (Oral Oncol. 2004)
    608. Early alterations in serum creatine kinase and total cholesterol following high intensity eccentric muscle actions. (PubMed id 15470318)9 Shahbazpour N....Carson R.G. (J Sports Med Phys Fitness 2004)
    609. Chronic lower extremity ischemia: a human model of ischemic tolerance. (PubMed id 15540688)9 Badhwar A....Potter R.F. (Can J Surg 2004)
    610. Immunohistochemical profiles of Mallory body by a panel of anti-cytokeratin antibodies. (PubMed id 15221653)9 Pei R.J....Tsubura A. (Med Electron Microsc 2004)
    611. Effects of prolonged strenuous exercise (marathon running) on biochemical and haematological markers used in the investigation of patients in the emergency department. (PubMed id 15155430)9 Smith J.E....Pedoe D.T. (Br J Sports Med 2004)
    612. Rhabdomyolysis in response to weight-loss herbal medicine. (PubMed id 15201651)9 Mansi I.A. and Huang J. (Am. J. Med. Sci. 2004)
    613. Isoleucine 69 and valine 325 form a specificity pocket in human muscle creatine kinase. (PubMed id 15504039)9 Novak W.R....Babbitt P.C. (Biochemistry 2004)
    614. Treatment with non-hypercalcemic analogs of 1,25-dihydroxyvitamin D3 increases responsiveness to 17beta-estradiol, dihydrotestosterone or raloxifene in primary human osteoblasts. (PubMed id 15084353)9 Katzburg S....Somjen D. (J. Steroid Biochem. Mol. Biol. 2004)
    615. [Comparison of fetal ECG recordings using STAN S21 analyser and external ECG of newborns, in relation to enzymatic ischaemic markers and acid-base parameters in umbilical blood]. (PubMed id 15754570)9 Zikitek M....Ronin-Walknowska E. (Ginekol. Pol. 2004)
    616. [Clinical observation on treatment of SARS with combination of chaihu droplet pill and huoxiang zhengqi droplet pill]. (PubMed id 15143718)9 Li H....Tang K.C. (Zhongguo Zhong Xi Yi Jie He Za Zhi 2004)
    617. In vivo 31P magnetic resonance spectroscopy of human brain at 7 T: an initial experience. (PubMed id 12541238)9 Lei H....Chen W. (Magn Reson Med 2003)
    618. Reversible acute renal failure associated with hypothyroidism: report of four cases with a brief review of literature. (PubMed id 15012734)9 Mooraki A....Bastani B. (Nephrology (Carlton) 2003)
    619. A dietary supplement attenuates IL-6 and CRP after eccentric exercise in untrained males. (PubMed id 14652498)9 Phillips T....Leeuwenburgh C. (Med Sci Sports Exerc 2003)
    620. [Cardioprotective effects of diltiazem infusion in the perioperative period in patients undergoing coronary artery bypass grafting with extracorporeal circulation]. (PubMed id 14521738)9 Zhang P....Wang G.L. (Zhonghua Yi Xue Za Zhi 2003)
    621. Late-onset distal muscular dystrophy affecting the posterior calves. (PubMed id 14506716)9 Katz J.S....Amato A.A. (amp 2003)
    622. Statin-associated myopathy. (PubMed id 12672737)9 Thompson P.D....Karas R.H. (JAMA 2003)
    623. Creatine kinase BB in brain in schizophrenia. (PubMed id 14608589)9 Burbaeva G.S.h....Boksha I.S. (World J. Biol. Psychiatry 2003)
    624. Smooth muscle and NMR review: an overview of smooth muscle metabolism. (PubMed id 12701805)9 Nakayama S. and Clark J.F. (Mol. Cell. Biochem. 2003)
    625. Rhabdomyolysis in diabetic ketoacidosis. (PubMed id 14655521)9 Casteels K....Van Geet C. (Pediatr Diabetes 2003)
    626. D-2-hydroxyglutaric acid inhibits creatine kinase activity from cardiac and skeletal muscle of young rats. (PubMed id 14511354)9 da Silva C.G....Wajner M. (Eur. J. Clin. Invest. 2003)
    627. Skeletal muscle enzymes as predictors of 24-h energy metabolism in reduced-obese persons. (PubMed id 12936925)9 Doucet E....Joanisse D.R. (Am. J. Clin. Nutr. 2003)
    628. Successful orthotopic liver transplantation after trimethoprim-sulfamethoxazole associated fulminant liver failure. (PubMed id 14703931)9 Zaman F....Zibari G.B. (Clin Transplant 2003)
    629. Serum creatine kinase is elevated in patients with Parkinson's disease: a case controlled study. (PubMed id 12735914)9 Takubo H....Mizuno Y. (amp 2003)
    630. New IFCC reference procedures for the determination of catalytic activity concentrations of five enzymes in serum: preliminary upper reference limits obtained in hospitalized subjects. (PubMed id 12482620)9 Schumann G. and Klauke R. ( international journal of clinical chemistry 2003)
    631. Changes in serum biochemical responses during cardiac rehabilitation. (PubMed id 12750582)9 Brodie D.A....Jackson M. (Med Sci Sports Exerc 2003)
    632. Early use of beta-blockers is associated with attenuation of serum C-reactive protein elevation and favorable short-term prognosis after acute myocardial infarction. (PubMed id 12589122)9 Anzai T....Ogawa S. (Cardiology 2003)
    633. Metastatic chondroblastoma with elevated creatine kinase and paraneoplastic neurologic autoimmunity. (PubMed id 14608202)9 Joshi D.D....Lennon V.A. (J. Pediatr. Hematol. Oncol. 2003)
    634. Higher energy monophasic DC cardioversion for persistent atrial fibrillation: is it time to start at 360 joules? (PubMed id 12848792)9 Boos C....More R.S. (Ann Noninvasive Electrocardiol 2003)
    635. Laminin induces the expression of cytokeratin 19 in hepatocellular carcinoma cells growing in culture. (PubMed id 12717831)9 Su Q....Wang C.M. (World J. Gastroenterol. 2003)
    636. Clinical study of Japanese spotted fever and its aggravating factors. (PubMed id 12673413)9 Kodama K....Chikahira Y. (J. Infect. Chemother. 2003)
    637. Human immunodeficiency virus-associated polymyositis: a longitudinal study of outcome. (PubMed id 12687507)9 Johnson R.W....Reveille J.D. (Arthritis Rheum. 2003)
    638. Absence of myocardial involvement in children victims of Crotalus durissus terrificus envenoming. (PubMed id 14757204)9 Cupo P....Hering S.E. (Toxicon 2003)
    639. Differential diagnosis of high serum creatine kinase levels in systemic lupus erythematosus. (PubMed id 12739036)9 Richter J.G....Schneider M. (Rheumatol. Int. 2003)
    640. [Comparison of perioperative myocardial enzyme changes among congenital, rheumatic and coronary artery diseases]. (PubMed id 14505535)9 Chen C.C....Hu Y.L. (Zhonghua Wai Ke Za Zhi 2003)
    641. Plasma creatine kinase activity and glutathione after eccentric exercise. (PubMed id 12783040)9 Lee J. and Clarkson P.M. (Med Sci Sports Exerc 2003)
    642. Clinical and scintigraphic (99mTc-MIBI SPECT) heart evaluation in young acutely carbon monoxide poisoned patients. (PubMed id 14569889)9 Hubalewska-HoA8a A....Huszno B. (Prz. Lek. 2003)
    643. Myocardial and lung injury after cardiopulmonary bypass: role of interleukin (IL)-10. (PubMed id 12842524)9 Giomarelli P....Biagioli B. (Ann. Thorac. Surg. 2003)
    644. Risperidone-induced marked elevation of serum creatine kinase in adolescence. A case report. (PubMed id 14663658)9 Holtmann M....Schmidt M.H. (Pharmacopsychiatry 2003)
    645. Erdosteine prevents doxorubicin-induced cardiotoxicity in rats. (PubMed id 12902208)9 Yagmurca M....Irmak M.K. (Pharmacol. Res. 2003)
    646. [Study on the myocardiac injury in patients with severe acute respiratory syndrome]. (PubMed id 12921602)9 Guan Y.J....Lei C.L. (Zhonghua Nei Ke Za Zhi 2003)
    647. Altered cytokeratin expression in actinic cheilitis. (PubMed id 12680953)9 dos Santos AraA_jo V.C. (J. Cutan. Pathol. 2003)
    648. Overloaded training increases exercise-induced oxidative stress and damage. (PubMed id 12904636)9 Palazzetti S....Margaritis I. (Can J Appl Physiol 2003)
    649. Evaluation of human serum albumin cobalt binding assay for the assessment of myocardial ischemia and myocardial infarction. (PubMed id 12651810)9 Bhagavan N.V....Ha C.E. (Clin. Chem. 2003)
    650. Myocardial stress after competitive exercise in professional road cyclists. (PubMed id 14523304)9 KAPnig D....Dickhuth H.H. (Med Sci Sports Exerc 2003)
    651. Utility of troponin I in patients with cocaine-associated chest pain. (PubMed id 12359538)9 Kontos M.C....Jesse R.L. (Acad Emerg Med 2002)
    652. Evolution of arginine deiminase (ADI) pathway genes. (PubMed id 12450748)9 ZA_A+iga M....GonzA!lez-Candelas F. (Mol. Phylogenet. Evol. 2002)
    653. Snakebites by Crotalus durissus ssp in children in Campinas, SALo Paulo, Brazil. (PubMed id 12163905)9 Bucaretchi F....Vieira R.J. (Rev. Inst. Med. Trop. Sao Paulo 2002)
    654. [Coronary flow velocity reserve and collateral resistance after recanalization of chronic total coronary occlusions and periprocedural CK and cTNI elevation]. (PubMed id 12442197)9 Bahrmann P....Werner G.S. (Z Kardiol 2002)
    655. Membrane leakage and increased content of Na+ -K+ pumps and Ca2+ in human muscle after a 100-km run. (PubMed id 11960939)9 Overgaard K....Clausen T. (J. Appl. Physiol. 2002)
    656. Lead ion effect on creatine kinase: equilibrium and kinetic studies of inactivation and conformational changes. (PubMed id 11906827)9 Zhou H.W....Zhou H.M. (amp 2002)
    657. Recurrent acute myositis after allogeneic bone marrow transplantation for myelodysplasia. (PubMed id 12186701)9 Sato N....Ikeda Y. (Hematology 2002)
    658. Women with pregnancy-related polymyositis and high serum CK levels in the newborn. (PubMed id 11839858)9 Messina S....Sciacco M. (Neurology 2002)
    659. Comparison of troponin T and enzyme levels in acute myocardial infarction and skeletal muscle injury. (PubMed id 12688092)9 Majeed R....Baseer A. (J Ayub Med Coll Abbottabad 2002)
    660. Plasma carnosine concentration: diurnal variation and effects of age, exercise and muscle damage. (PubMed id 12405702)9 Dunnett M....Harris P.A. (Equine Vet J Suppl 2002)
    661. Retrospective study of a large population of patients with asymptomatic or minimally symptomatic raised serum creatine kinase levels. (PubMed id 11993531)9 Prelle A....Moggio M. (J. Neurol. 2002)
    662. The creatine kinase system is essential for optimal refill of the sarcoplasmic reticulum Ca2+ store in skeletal muscle. (PubMed id 11734556)9 de Groof A.J....Koopman W.J. (J. Biol. Chem. 2002)
    663. Colchicine neuromyopathy: a report of six cases. (PubMed id 12371628)9 Altiparmak M.R....Serdengecti K. (Clin. Exp. Rheumatol. 2002)
    664. Acute changes in selected serum enzyme and metabolite concentrations in 12- to 14-yr.-old athletes after an all-out 100-m swimming sprint. (PubMed id 12578257)9 Fu F.H....Kong Z.W. (Percept Mot Skills 2002)
    665. Subunit interaction slows the unfolding of the N-terminal domain of creatine kinase in urea. (PubMed id 12600269)9 Guo Z....Wang X.C. (Biochemistry Mosc. 2002)
    666. HCC CKs are altered histones during tumor transformation in hepatoma. (PubMed id 15080494)9 Liu Y.H....Lai Y.S. (Res. Commun. Mol. Pathol. Pharmacol. 2002)
    667. Intramuscular administration of recombinant adeno-associated virus 2 alpha-1 antitrypsin (rAAV-SERPINA1) vectors in a nonhuman primate model: safety and immunologic aspects. (PubMed id 12231168)9 Song S....Flotte T.R. (Mol. Ther. 2002)
    668. Evaluation of enzymes in serum and cerebrospinal fluid in cases of stroke. (PubMed id 12577113)9 Parakh N....Jain A. (Neurol India 2002)
    669. Incidence of high-risk acute coronary syndromes and eligibility for glycoprotein IIb/IIIa inhibitors among patients admitted for possible myocardial ischemia. (PubMed id 11773914)9 Kontos M.C....Jesse R.L. (Am. Heart J. 2002)
    670. Troponin T concentrations 72 hours after myocardial infarction as a serological estimate of infarct size. (PubMed id 12010931)9 Licka M....KA1bler W. (Heart 2002)
    671. Cardiac injury markers and a failed algorithm: can accurate assessment of acute myocardial infarction be cost effective? (PubMed id 12188242)9 Abadie J.M. (Mil Med 2002)
    672. Calpain and mitochondria in ischemia/reperfusion injury. (PubMed id 12042324)9 Chen M....Gottlieb R.A. (J. Biol. Chem. 2002)
    673. [Acute fluoroacetamide poisoning with main damage to the heart]. (PubMed id 14694721)9 Lin J....Xia G. (Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2002)
    674. Prognostic implication of cardiac troponin T increase following stent implantation. (PubMed id 12010937)9 Herrmann J....Erbel R. (Heart 2002)
    675. Antioxidant status and muscle cell leakage during endurance exercise. (PubMed id 12405670)9 Hargreaves B.J....Harris P.A. (Equine Vet J Suppl 2002)
    676. Guiding catheter aspiration to prevent embolic events during saphenous vein graft intervention. (PubMed id 12476653)9 Morales P.A. and Heuser R.R. (J Interv Cardiol 2002)
    677. [Biochemical marker for myocardial injury]. (PubMed id 12652682)9 Nakai K....Suwabe A. (Rinsho Byori 2002)
    678. Physical activity changes the regulation of mitochondrial respiration in human skeletal muscle. (PubMed id 12181291)9 Zoll J....Mettauer B. (J. Physiol. (Lond.) 2002)
    679. The physical state and plasma biochemical profile of young calves on arrival at a slaughter plant. (PubMed id 16032182)9 Stafford K.J....Ward R.N. (N Z Vet J 2001)
    680. Mutagenesis of two acidic active site residues in human muscle creatine kinase: implications for the catalytic mechanism. (PubMed id 11258919)9 Cantwell J.S....Babbitt P.C. (Biochemistry 2001)
    681. &quot;Liver function tests&quot; are not always tests of liver function. (PubMed id 11426492)9 Korones D.N....Palis J. (Am. J. Hematol. 2001)
    682. Matrix metalloproteinases (MMPs) in breast cancer cell lines of different tumorigenicity. (PubMed id 11911253)9 Bachmeier B.E....Sommerhoff C.P. (Anticancer Res. 2001)
    683. Metabolic characteristics of the deltoid muscle in patients with chronic obstructive pulmonary disease. (PubMed id 11488330)9 Gea J.G....Broquetas J. (Eur. Respir. J. 2001)
    684. Relationship between kinetic and equilibrium folding intermediates of creatine kinase. (PubMed id 11467829)9 Zhu L....Zhou J.M. (Biochem. Biophys. Res. Commun. 2001)
    685. Corrected TIMI frame counts correlate with stenosis severity and infarct zone wall motion after thrombolytic therapy. (PubMed id 11275924)9 Amos D.J....White H.D. (Am. Heart J. 2001)
    686. Release of muscle proteins after downhill running in male and female subjects. (PubMed id 11169232)9 Sorichter S....Puschendorf B. (amp 2001)
    687. [Macromolecular creatinine kinase in patients diagnosed with ulcerative colitis]. (PubMed id 11219135)9 PAcrez Calle J.L....GonzA!lez Lara V. (Gastroenterol Hepatol 2001)
    688. Evaluation of aminotransferase elevations in a bodybuilder using anabolic steroids: hepatitis or rhabdomyolysis? (PubMed id 11476029)9 Pertusi R....McConathy W.J. (J Am Osteopath Assoc 2001)
    689. Estrogen-like activity of glabrene and other constituents isolated from licorice root. (PubMed id 11595510)9 Tamir S....Vaya J. (J. Steroid Biochem. Mol. Biol. 2001)
    690. Creatine loading and resting skeletal muscle phosphocreatine flux: a saturation-transfer NMR study. (PubMed id 11502426)9 Wiedermann D....MAPller H.E. (MAGMA 2001)
    691. Cardiac troponin and beta-type myosin heavy chain concentrations in patients with polymyositis or dermatomyositis. (PubMed id 11282091)9 Erlacher P....Mair J. ( international journal of clinical chemistry 2001)
    692. Clinical evaluation of the ACS:180 cardiac troponin I assay. (PubMed id 11587129)9 Collinson P.O....Gaze D.C. (Ann. Clin. Biochem. 2001)
    693. Creatine transporter and mitochondrial creatine kinase protein content in myopathies. (PubMed id 11317279)9 Tarnopolsky M.A....Wallimann T. (amp 2001)
    694. Minor myocardial injury after elective uncomplicated successful PTCA with or without stenting: detection by cardiac troponins. (PubMed id 11387602)9 Saadeddin S.M....Ferns G.A. (amp 2001)
    695. Creatine kinase gene mutation in a patient with muscle creatine kinase deficiency. (PubMed id 11673364)9 Yamamichi H....Koshiba M. (Clin. Chem. 2001)
    696. Reactivation kinetics of guanidine hydrochloride-denatured creatine kinase measured using the substrate reaction. (PubMed id 11330350)9 Park Y.D....Zhou H.M. (J. Protein Chem. 2001)
    697. Non-Hodgkin's lymphoma of the ascending colon in a patient with becker muscular dystrophy: report of a case. (PubMed id 11766073)9 Uotani H....Tsukada K. (Surg. Today 2001)
    698. Diagnosis of acute myocardial infarction in angiographically documented occluded infarct vessel : limitations of ST-segment elevation in standard and extended ECG leads. (PubMed id 11713132)9 Schmitt C....SchAPmig A. (Chest 2001)
    699. [Incompatibility of olanzapine and amisulpride in multisystemic myotonic myopathy]. (PubMed id 11572107)9 Pedrosa Gil F....RA1ther E. (Nervenarzt 2001)
    700. Normalization of creatine kinase level during pregnancy in idiopathic hyperCKemia. (PubMed id 11532557)9 Fukutake T. and Hattori T. (Clin Neurol Neurosurg 2001)
    701. Pharmacokinetics and residues in milk of oxytetracyclines administered parenterally to dairy goats. (PubMed id 11549049)9 Rule R....Garcia J. (Aust. Vet. J. 2001)
    702. Levels of vasodilators (SP, CGRP) and vasoconstrictor (NPY) peptides in early human burns. (PubMed id 11264654)9 Onuoha G.N. and Alpar E.K. (Eur. J. Clin. Invest. 2001)
    703. The effects of sprint (300 m) running on plasma lactate, uric acid, creatine kinase and lactate dehydrogenase in competitive hurdlers and untrained men. (PubMed id 11533559)9 KlapciA8ska B....Grzesiok K. (J Sports Med Phys Fitness 2001)
    704. Role of creatine kinase isoenzymes on muscular and cardiorespiratory endurance: genetic and molecular evidence. (PubMed id 11708401)9 Echegaray M. and Rivera M.A. (Sports Med 2001)
    705. Serum neopterin and activity of coronary artery disease. (PubMed id 11975809)9 Auer J....Eber B. (Heart Dis 2001)
    706. An overview of biochemical markers in acute coronary syndromes. (PubMed id 11467201)9 Olukoga A. and Donaldson D. (J R Soc Promot Health 2001)
    707. Relationship between myocardial damage and C-reactive protein levels immediately after onset of acute myocardial infarction. (PubMed id 11216827)9 Kimura K....Umemura S. (Jpn. Circ. J. 2001)
    708. Involvement of nervous system in maternally inherited diabetes and deafness (MIDD) with the A3243G mutation of mitochondrial DNA. (PubMed id 11240563)9 Lien L.M....Wei Y.H. (Acta Neurol. Scand. 2001)
    709. Skeletal muscle metabolism in overweight and post-overweight women: an isometric exercise study using (31)P magnetic resonance spectroscopy. (PubMed id 11571592)9 Newcomer B.R....Weinsier R.L. (Int. J. Obes. Relat. Metab. Disord. 2001)
    710. Creatine kinase revisited. (PubMed id 19078624)9 Katiriji B. and Al Jaberi M.M. (J Clin Neuromuscul Dis 2001)
    711. Postischemic reperfusion injury can be attenuated by oxygen tension control. (PubMed id 11266197)9 Kaneda T....Oku H. (Jpn. Circ. J. 2001)
    712. Clinical and experimental results on cardiac troponin expression in Duchenne muscular dystrophy. (PubMed id 11238296)9 Hammerer-Lercher A....Mair J. (Clin. Chem. 2001)
    713. Crystal structure of human ubiquitous mitochondrial creatine kinase. (PubMed id 10737943)9 Eder M.... Schlattner U. (Proteins 2000)
    714. Assessment of the myotoxicity of pharmaceutical buffers using an in vitro muscle model: effect of pH, capacity, tonicity, and buffer type. (PubMed id 10669926)9 Napaporn J....Brazeau G.A. (Pharm Dev Technol 2000)
    715. Cytokeratin expression in seminoma of the human testis. (PubMed id 10761461)9 Cheville J.C....Pankratz V.S. (Am. J. Clin. Pathol. 2000)
    716. [Clinical study of Astragalus injection plus ligustrazine in protecting myocardial ischemia reperfusion injury]. (PubMed id 11789206)9 Zhou S....Zhang W. (Zhongguo Zhong Xi Yi Jie He Za Zhi 2000)
    717. Tacrolimus limits polymorphonuclear leucocyte accumulation and protects against myocardial ischaemia- reperfusion injury. (PubMed id 10731442)9 Squadrito F....Caputi A.P. (J. Mol. Cell. Cardiol. 2000)
    718. Training and overtraining markers in selected sport events. (PubMed id 10647551)9 Hartmann U. and Mester J. (Med Sci Sports Exerc 2000)
    719. Postoperative blood salvage and reinfusion in spinal surgery: blood quality, effectiveness and impact on patient blood parameters. (PubMed id 11189913)9 SebastiA!n C....MuA+oz M. (Eur Spine J 2000)
    720. Cytokeratin staining in Merkel cell carcinoma: an immunohistochemical study of cytokeratins 5/6, 7, 17, and 20. (PubMed id 11127923)9 Jensen K....Rouse R.V. (amp 2000)
    721. Relationship between gastro-intestinal complaints and endotoxaemia, cytokine release and the acute-phase reaction during and after a long-distance triathlon in highly trained men. (PubMed id 10600658)9 Jeukendrup A.E....Wagenmakers A.J. (Clin. Sci. 2000)
    722. Correlation of antemortem serum creatine kinase, creatine kinase-MB, troponin I, and troponin T with cardiac pathology. (PubMed id 10702520)9 Ooi D.S....Veinot J.P. (Clin. Chem. 2000)
    723. Cardiac toxicity of intravenous terbutaline for the treatment of severe asthma in children: a prospective assessment. (PubMed id 10891825)9 Chiang V.W....Weiner D.L. (J. Pediatr. 2000)
    724. Long-term experience with an accelerated protocol for diagnosis of chest pain. (PubMed id 11035571)9 Caragher T.E....Barr L.A. (amp 2000)
    725. Malignant insulinoma which expressed a unique creatine kinase isoenzyme: clinical value of arterial embolization as a palliative therapy. (PubMed id 10852167)9 Hayashi M....Fujita T. (Intern. Med. 2000)
    726. Calcium regulation by skeletal muscle membranes of horses with recurrent exertional rhabdomyolysis. (PubMed id 10714513)9 Ward T.L....Mickelson J.R. (Am. J. Vet. Res. 2000)
    727. Postcompetition elevation of muscle enzyme levels in professional football players. (PubMed id 11104450)9 Garry J.P. and McShane J.M. (MedGenMed 2000)
    728. Laboratory diagnosis of patients with acute chest pain. (PubMed id 10905753)9 PenttilAo I....Rantanen T. (Clin. Chem. Lab. Med. 2000)
    729. Myxedema coma of both primary and secondary origin, with non-classic presentation and extremely elevated creatine kinase. (PubMed id 11014385)9 Benvenga S....Trimarchi F. (Horm. Metab. Res. 2000)
    730. Induced fit in arginine kinase. (PubMed id 10692338)9 Zhou G....Chapman M.S. (Biophys. J. 2000)
    731. Discordant results of CK-MB and troponin I measurements: a review of 14 cases. (PubMed id 10807160)9 Bennett A.E. and Bertholf R.L. (Ann. Clin. Lab. Sci. 2000)
    732. Monitoring of impending myocardial damage after pleuropneumonectomy and intraoperative photodynamic therapy for malignant pleural mesothelioma using biochemical markers. (PubMed id 10732455)9 Klaase J.M....Baas P. (Photochem. Photobiol. 2000)
    733. Diagnosis of dermatomyositis and polymyositis: a study of 102 cases. (PubMed id 11018813)9 Scola R.H....Iwamoto F.M. (Arq Neuropsiquiatr 2000)
    734. [The role of biochemical markers of myocardial damage in clinical practice: the diagnosis of infarct and risk stratification. The Intersociety Interdisciplinary Study Group of the ANMCO-SIBioC-SIMeL, Markers of Muocardial Lesions. L'Associazione Nazionale Medici Cardiologi Ospedalieri-SocietA Italiana di Biochimica Clinica-SocietA Italiana di Medicina di Laboratorio]. (PubMed id 10832120)9 Ottani F....Zaninotto M. (Ital Heart J Suppl 2000)
    735. Transaminitis in Duchenne's muscular dystrophy. (PubMed id 11269976)9 Tay S.K....Low P.S. (Ann. Acad. Med. Singap. 2000)
    736. Estrogen and gender effects on muscle damage, inflammation, and oxidative stress. (PubMed id 10953066)9 Tiidus P.M. (Can J Appl Physiol 2000)
    737. Active recovery reduces the decrease in circulating white blood cells after exercise. (PubMed id 11156284)9 Wigernaes I....mme S.B. (Int J Sports Med 2000)
    738. [Lysosomal glycogen storage disease with normal acid maltase (Danon) without apparent cardiomyopathy and mental retardation]. (PubMed id 10885338)9 Kawamura H....Tadokoro M. (Rinsho Shinkeigaku 2000)
    739. Interferon treatment for dilated cardiomyopathy and striated myopathy associated with hepatitis C virus infection based on serial measurements of serum concentrations of cardiac troponin T. (PubMed id 10783058)9 Sato Y....Matsumori A. (Jpn. Circ. J. 2000)
    740. Efficacy of rescue thrombolysis in patients with acute myocardial infarction: preliminary findings. (PubMed id 10755205)9 Sarullo F.M....Mauri F. (Cardiovasc Drugs Ther 2000)
    741. Clinical evaluation of the first medical whole blood, point-of-care testing device for detection of myocardial infarction. (PubMed id 11017938)9 Apple F.S....Murakami M.M. (Clin. Chem. 2000)
    742. Phosphorylation of the beta-amyloid precursor protein at the cell surface by ectocasein kinases 1 and 2. (PubMed id 10806211)9 Walter J.... Haass C. (J. Biol. Chem. 2000)
    743. The cytokeratin profile of medullary carcinoma of the breast. (PubMed id 10931242)9 Tot T. (Histopathology 2000)
    744. Cardiac fatigue following prolonged endurance exercise of differing distances. (PubMed id 10862531)9 Whyte G.P....McKenna W.J. (Med Sci Sports Exerc 2000)
    745. Oxidative modification of creatine kinase BB in Alzheimer's disease brain. (PubMed id 10820214)9 Aksenov M....Markesbery W.R. (J. Neurochem. 2000)
    746. Serum levels of vascular endothelial growth factor in patients with angina pectoris and acute myocardial infarction. (PubMed id 12906138)9 Yin R....Wu H. (Chin. Med. Sci. J. 2000)
    747. Cardioprotective effects of the Na(+)/H(+) exchange inhibitor cariporide in patients with acute anterior myocardial infarction undergoing direct PTCA. (PubMed id 10869261)9 Rupprecht H.J....Drexler H. (Circulation 2000)
    748. Force and EMG power spectrum during and after eccentric and concentric fatigue. (PubMed id 11018439)9 Linnamo V....Komi P.V. (J Electromyogr Kinesiol 2000)
    749. Interactions between beta-enolase and creatine kinase in the cytosol of skeletal muscle cells. (PubMed id 10657248)9 Foucault G....Arrio-Dupont M. (Biochem. J. 2000)
    750. The relationship between creatine kinase kinetics and exercise intensity in human forearm is unchanged by age. (PubMed id 10913033)9 HorskA! A....Spencer R.G. (Am. J. Physiol. Endocrinol. Metab. 2000)
    751. Chest pain with nondiagnostic electrocardiogram in the emergency department: a randomized controlled trial of two cardiac marker regimens. (PubMed id 10862229)9 Dagnone E....Morton R. (CMAJ 2000)
    752. Elevated serum creatine kinase activity in a patient with acute pancreatitis. (PubMed id 10622080)9 Randeva H.S....Press M. (Int. J. Clin. Pract. 1999)
    753. Effect of exhausting stretch-shortening cycle exercise on the time course of mechanical behaviour in the drop jump: possible role of muscle damage. (PubMed id 10029337)9 Horita T....KyrAPlAoinen H. (Eur J Appl Physiol Occup Physiol 1999)
    754. Influence of mammary artery as a bypass vessel on the results of seven biochemical assays after coronary artery bypass surgery. (PubMed id 10370734)9 Harff G.A....SchAPnberger J.P. (Ann. Clin. Biochem. 1999)
    755. The use of selected plasma enzyme activities for the diagnosis of fatty liver-hemorrhagic syndrome in laying hens. (PubMed id 10611993)9 Diaz G.J....Julian R.J. (Avian Dis. 1999)
    756. Characteristics and prognosis of patients with suspected acute myocardial infarction and elevated MB relative index but normal total creatine kinase. (PubMed id 10569646)9 Lloyd-Jones D.M....O'Donnell C.J. (Am. J. Cardiol. 1999)
    757. Measurement of myocardial infarct size from plasma fatty acid-binding protein or myoglobin, using individually estimated clearance rates. (PubMed id 10690308)9 de Groot M.J....Hermens W.T. (Cardiovasc. Res. 1999)
    758. Creatine and cyclocreatine treatment of human colon adenocarcinoma xenografts: 31P and 1H magnetic resonance spectroscopic studies. (PubMed id 9888469)9 Kristensen C.A....Koretsky A.P. (Br. J. Cancer 1999)
    759. Impact of three different types of exercise on components of the inflammatory response. (PubMed id 10502079)9 Brenner I.K....Shephard R.J. (Eur J Appl Physiol Occup Physiol 1999)
    760. Blood leukocyte and glutamine fluctuations after eccentric exercise. (PubMed id 10452230)9 Miles M.P....Clarkson P.M. (Int J Sports Med 1999)
    761. Characterization of the cellular component of polymorphous low-grade adenocarcinoma by immunohistochemistry and electron microscopy. (PubMed id 10435151)9 AraA_jo V....AraA_jo N. (Oral Oncol. 1999)
    762. [Creatine kinase BB activity in the serum and bronchial aspirate of preterm newborns with respiratory distress syndrome]. (PubMed id 10652804)9 SA!nchez Navarro M.R....Samaniego MuA+oz M. (An. Esp. Pediatr. 1999)
    763. Nucleotide binding to creatine kinase: an isothermal titration microcalorimetry study. (PubMed id 10561506)9 Forstner M....Wallimann T. (FEBS Lett. 1999)
    764. Decreased serum biochemical markers of muscle origin in patients with ankylosing spondylitis. (PubMed id 10460186)9 Giltay E.J....Dijkmans B.A. (Ann. Rheum. Dis. 1999)
    765. The relationship between periprocedural myocardial infarction and subsequent target vessel revascularization following percutaneous coronary revascularization: insights from the EPIC trial. Evaluation of IIb/IIIa platelet receptor antagonist 7E3 in Preventing Ischemic Complications. (PubMed id 10080464)9 Narins C.R....Topol E.J. (J. Am. Coll. Cardiol. 1999)
    766. High levels of BCL-2 messenger RNA detected by in situ hybridization in human hepatocellular and cholangiocellular carcinomas. (PubMed id 10617275)9 Fiorentino M....Grigioni W.F. (Diagn. Mol. Pathol. 1999)
    767. Relation of minor cardiac troponin I elevation to late cardiac events after uncomplicated elective successful percutaneous transluminal coronary angioplasty for angina pectoris. (PubMed id 10404851)9 Bertinchant J.P....Nigond J. (Am. J. Cardiol. 1999)
    768. Anabolic steroid-induced hepatotoxicity: is it overstated? (PubMed id 10336050)9 Dickerman R.D....McConathy W.J. (Clin J Sport Med 1999)
    769. Early diagnosis of acute myocardial infarction in patients without ST-segment elevation. (PubMed id 10073813)9 Kontos M.C....Jesse R.L. (Am. J. Cardiol. 1999)
    770. [Serum markers for ischemic myocardial damage]. (PubMed id 10661020)9 Fontes J.P....Ribeiro V.G. (Rev Port Cardiol 1999)
    771. Short-term effects of marathon running: no evidence of cardiac dysfunction. (PubMed id 10527313)9 LucA-a A....Chicharro J.L. (Med Sci Sports Exerc 1999)
    772. Effect of diet on thoroughbred horses with recurrent exertional rhabdomyolysis performing a standardised exercise test. (PubMed id 10659299)9 MacLeay J.M....Kaese H. (Equine Vet J Suppl 1999)
    773. Improved detection of radiofrequency current-induced minor myocardial injury by cardiac troponin T measurement. (PubMed id 10410480)9 Sribhen K....Chaithiraphan S. (J Med Assoc Thai 1999)
    774. Elevated cardiac troponin I predicts a high-risk angiographic anatomy of the culprit lesion in unstable angina. (PubMed id 10220629)9 Benamer H....Assayag P. (Am. Heart J. 1999)
    775. Naproxen does not alter indices of muscle damage in resistance-exercise trained men. (PubMed id 9927002)9 Bourgeois J....Tarnopolsky M. (Med Sci Sports Exerc 1999)
    776. [Myositis in the presence of slightly elevated creatine kinase values]. (PubMed id 10368712)9 van Vonderen M.G....Gans R.O. (Ned Tijdschr Geneeskd 1999)
    777. Increased cardiac troponin T and endothelin-1 concentrations in dialysis patients may indicate heart disease. (PubMed id 10462276)9 LAPwbeer C....Gutierrez A. (Nephrol. Dial. Transplant. 1999)
    778. Changes in plasma enzyme activity after intramuscular injection of bupivacaine into the human biceps brachii. (PubMed id 10606828)9 Nosaka K. and Sakamoto K. (Acta Physiol. Scand. 1999)
    779. Retrieval and analysis of particulate debris after saphenous vein graft intervention. (PubMed id 10440161)9 Webb J.G....Oesterle S. (J. Am. Coll. Cardiol. 1999)
    780. Rhabdomyolysis associated with concomitant use of atorvastatin and cyclosporine. (PubMed id 10573315)9 Maltz H.C....Cheigh J.S. (Ann Pharmacother 1999)
    781. Combined hyperlipidemia is associated with increased exercise-induced muscle protein release which is improved by triglyceride-lowering intervention. (PubMed id 10599982)9 Smit J.W....Erkelens D.W. (Metab. Clin. Exp. 1999)
    782. Creatine kinase and its CK-MB isoenzyme: the conventional marker for the diagnosis of acute myocardial infarction. (PubMed id 9950395)9 Robinson D.J. and Christenson R.H. (J Emerg Med 1999)
    783. Tissue and plasma enzyme activities in juvenile green iguanas. (PubMed id 10048552)9 Wagner R.A. and Wetzel R. (Am. J. Vet. Res. 1999)
    784. Normalization of creatine kinase level during arthritis in a patient with Becker muscular dystrophy. (PubMed id 9921868)9 Maegaki Y....Takeshita K. (Neurology 1999)
    785. Electrophoresis of creatine kinase isoforms: a highly sensitive fluorescence scanning method. (PubMed id 11593528)9 Zhao X....Yang Z. (Chin. Med. J. 1999)
    786. Strategies for the early diagnosis of acute myocardial infarction using biochemical markers. (PubMed id 10078116)9 Zaninotto M....Plebani M. (Am. J. Clin. Pathol. 1999)
    787. Comparison of the prognostic value of C-reactive protein and troponin I in patients with unstable angina pectoris. (PubMed id 9781965)9 Benamer H....Assayag P. (Am. J. Cardiol. 1998)
    788. Cytoplasmic extrusion and the switch from creatine kinase B to M isoform are completed by the commencement of epididymal transport in human and stallion spermatozoa. (PubMed id 9537287)9 Huszar G....Johnson L. (J. Androl. 1998)
    789. [Acute myocardial infarction diagnosis. The value of serum myoglobin levels, compared with creatine kinase MB fraction]. (PubMed id 9659712)9 Cavalcanti A.B....Zunino J.N. (Arq. Bras. Cardiol. 1998)
    790. Cardiac troponins in patients with renal dysfunction. (PubMed id 9635103)9 Collinson P.O....O'Donnell J. (Ann. Clin. Biochem. 1998)
    791. Differentiation between transmural perioperative myocardial infarction and subendocardial injury after coronary artery bypass grafting using biochemical tests, elaborated by cluster and discriminant analysis. (PubMed id 9681595)9 Harff G.A....SchAPnberger J.P. ( international journal of clinical chemistry 1998)
    792. Absence of myofibrillar creatine kinase and diaphragm isometric function during repetitive activation. (PubMed id 9516180)9 LaBella J.J....Watchko J.F. (J. Appl. Physiol. 1998)
    793. Thrombolytic therapy does not change the release ratios of enzymatic and non-enzymatic myocardial marker proteins. (PubMed id 9641361)9 Wodzig K.W....Hermens W.T. ( international journal of clinical chemistry 1998)
    794. A severe clinical and pathological variant of central core disease with possible autosomal recessive inheritance. (PubMed id 9829276)9 Manzur A.Y....Muntoni F. (Neuromuscul. Disord. 1998)
    795. Nonhypercalcemic analogs of vitamin D stimulate creatine kinase B activity in osteoblast-like ROS 17/2.8 cells and up-regulate their responsiveness to estrogens. (PubMed id 9618798)9 SAPmjen D....Kaye A.M. (Steroids 1998)
    796. [A new fluorescent scanning technique in quantitative determination of isoenzymes of creatine kinase]. (PubMed id 10682576)9 Zou M....Liu Y. (Hunan Yi Ke Da Xue Xue Bao 1998)
    797. [Diagnostic muscle MRI abnormality in a patient with inclusion body myositis]. (PubMed id 9805998)9 Ono K....Takamori M. (Rinsho Shinkeigaku 1998)
    798. Dietary control of exertional rhabdomyolysis in horses. (PubMed id 9604030)9 Valentine B.A....Thompson K.N. (J. Am. Vet. Med. Assoc. 1998)
    799. Specificity of cardiac troponins I and T in renal disease. (PubMed id 9594044)9 Willging S....Steinbach G. (Clin. Chem. Lab. Med. 1998)
    800. Biochemical markers of acute myocardial infarction: strategies for improving their clinical usefulness. (PubMed id 9635105)9 Katz I.A....Nelson G.I. (Ann. Clin. Biochem. 1998)
    801. Analysis of creatine kinase activity in 504 patients with proximal spinal muscular atrophy types I-III from the point of view of progression and severity. (PubMed id 9605392)9 Rudnik-SchAPneborn S....Zerres K. (Eur. Neurol. 1998)
    802. Hypocalcemic induced increase in creatine kinase in rats. (PubMed id 9588528)9 Ishikawa T....Horie T. (Pediatr. Neurol. 1998)
    803. A case report of myolysis during high-dose amiodarone therapy for uncontrolled ventricular tachycardia. (PubMed id 9583467)9 Itoh K....Hotta N. (Jpn. Circ. J. 1998)
    804. Cost-effectiveness of cardiac troponin I in a systematic chest pain evaluation protocol: use of cardiac troponin I lowers length of stay for low-risk cardiac patients. (PubMed id 10178711)9 Anderson F.P....Jesse R.L. (Clin Lab Manage Rev 1998)
    805. [A patient with muscle pain after a journey to the tropics. Myocardial involvement in proximal myotonic myopathy]. (PubMed id 9810285)9 Held M....Jany B. (Dtsch. Med. Wochenschr. 1998)
    806. Plasma aspartate aminotransferase and creatine kinase activities in thoroughbred racehorses in relation to age, sex, exercise and training. (PubMed id 9638076)9 Harris P.A....Gray J. (Vet. J. 1998)
    807. Abnormal increase of creatine kinase plasma levels following muscle exercise in nephrotic patients. (PubMed id 9736821)9 Cupisti A....Barsotti G. (Nephron 1998)
    808. Muscle unloading induces slow to fast transitions in myofibrillar but not mitochondrial properties. Relevance to skeletal muscle abnormalities in heart failure. (PubMed id 9925374)9 Bigard A.X....Ventura-Clapier R. (J. Mol. Cell. Cardiol. 1998)
    809. Analytical performance and clinical application of a new rapid bedside assay for the detection of serum cardiac troponin I. (PubMed id 9732978)9 Heeschen C....Hamm C.W. (Clin. Chem. 1998)
    810. Detection of reperfusion after thrombolytic therapy by the analysis of released biochemical markers. (PubMed id 9777141)9 Cross D.B. (Aust N Z J Med 1998)
    811. Clinical value of creatinine kinase in the diagnosis of ectopic pregnancy. (PubMed id 9701684)9 Vitoratos N....Chryssikopoulos A. (Gynecol. Obstet. Invest. 1998)
    812. Some new aspects of creatine kinase (CK): compartmentation, structure, function and regulation for cellular and mitochondrial bioenergetics and physiology. (PubMed id 9914824)9 Wallimann T....Brdiczka D. (Biofactors 1998)
    813. Clinical features of polymyositis/dermatomyositis with steroid-resistant interstitial lung disease. (PubMed id 9745852)9 Takada T....Arakawa M. (Intern. Med. 1998)
    814. Heart failure: is there an energy deficit contributing to contractile dysfunction? (PubMed id 9538931)9 Vogt A.M. and KA1bler W. (Basic Res. Cardiol. 1998)
    815. The distinction between coronary and myocardial reperfusion after thrombolytic therapy by clinical markers of reperfusion. (PubMed id 9809943)9 Matetzky S....Hod H. (J. Am. Coll. Cardiol. 1998)
    816. Laminin alpha 2-chain gene mutations in two siblings presenting with limb-girdle muscular dystrophy. (PubMed id 9829280)9 Naom I....Muntoni F. (Neuromuscul. Disord. 1998)
    817. Comparative study of the clinical presentation of Legionella pneumonia and other community-acquired pneumonias. (PubMed id 9596294)9 Sopena N....Tudela P. (Chest 1998)
    818. Acute 2,4-dichlorophenoxyacetic acid intoxication in broiler chicks. (PubMed id 9565231)9 Morgulis M.S....Palermo-Neto J. (Poult. Sci. 1998)
    819. Clinical correlates of granulomas in muscle. (PubMed id 9747915)9 Mozaffar T....Pestronk A. (J. Neurol. 1998)
    820. Peripheral monocytosis following acute myocardial infarction: incidence and its possible role as a bedside marker of the extent of cardiac injury. (PubMed id 9693172)9 Meisel S.R....David D. (Cardiology 1998)
    821. [Changes of serum myocardial enzymes in patients with malignant hematologic diseases]. (PubMed id 10682571)9 Tan D....Liu J. (Hunan Yi Ke Da Xue Xue Bao 1998)
    822. The influence of intersubunit cross-linking on the conformational changes of creatine kinase during denaturation by guanidine hydrochloride. (PubMed id 9315299)9 Zhu L....Zhou J.M. (Biochem. Mol. Biol. Int. 1997)
    823. Cardiac markers in the assessment of acute coronary syndromes. (PubMed id 9470339)9 Christenson R.H....Ohman E.M. (Md Med J 1997)
    824. Protease digestion studies of an equilibrium intermediate in the unfolding of creatine kinase. (PubMed id 9003404)9 Webb T....Morris G.E. (Biochem. J. 1997)
    825. Prognostic influence of elevated values of cardiac troponin I in patients with unstable angina. (PubMed id 9133515)9 Galvani M....Jaffe A.S. (Circulation 1997)
    826. Immediate external compression in the management of an acute muscle injury. (PubMed id 9200324)9 Thorsson O....Westlin N. (amp 1997)
    827. Serum enzymes in heat stroke: prognostic implication. (PubMed id 9216454)9 Alzeer A.H....Yrkendi M.S. (Clin. Chem. 1997)
    828. Prolonged elevation of serum creatine kinase (CK) without renal failure after ingestion of ecstasy. (PubMed id 9132664)9 Williams A. and Unwin R. (Nephrol. Dial. Transplant. 1997)
    829. [Problems in the interpretation of blood chemistry results in birds]. (PubMed id 9459838)9 Hochleithner M....KA1bba-Heiss A. (Tierarztl Prax Ausg K Kleintiere Heimtiere 1997)
    830. Infantile polymyositis with normal serum creatine kinase level. (PubMed id 9071493)9 TA1tA1ncA1oA9lu S....Uysal S. (amp 1997)
    831. Malignant hyperthermia testing in patients with persistently increased serum creatine kinase levels. (PubMed id 9141928)9 Weglinski M.R....Engel A.G. (Anesth. Analg. 1997)
    832. Use of serum creatine kinase MM isoforms for predicting the progression of left ventricular dilation in patients with hypertrophic cardiomyopathy. (PubMed id 9152783)9 Hina K....Tsuji T. (Jpn. Circ. J. 1997)
    833. Activation of sea-urchin sperm motility is accompanied by an increase in the creatine kinase exchange flux. (PubMed id 9230121)9 Dorsten F.A....Nicolay K. (Biochem. J. 1997)
    834. The role of cardiac troponin T and other new biochemical markers in evaluation and risk stratification of patients with acute chest pain syndromes. (PubMed id 9383587)9 Solymoss B.C....Gilfix B.M. (Clin Cardiol 1997)
    835. The sum of vectors method (SV) applied to lactate dehydrogenase isoenzymes and creatine kinase isoforms. (PubMed id 9086294)9 Salplachta J. ( international journal of clinical chemistry 1997)
    836. Rhabdomyolysis induced by epsilon-aminocaproic acid. (PubMed id 8997467)9 Seymour B.D. and Rubinger M. (Ann Pharmacother 1997)
    837. Rhabdomyolysis in patients with acute lymphoblastic leukemia. (PubMed id 9291634)9 Morales-Polanco M....Paredes-GonzA!lez E. (Arch. Med. Res. 1997)
    838. Correlation between serum creatine kinase activities and anorexia in cats. (PubMed id 9132484)9 Fascetti A.J....Mauldin G.N. (J. Vet. Intern. Med. 1997)
    839. Enzyme adaptations of human skeletal muscle during bicycle short-sprint training and detraining. (PubMed id 9429650)9 Linossier M.T....Denis C. (Acta Physiol. Scand. 1997)
    840. The seventh form of autosomal recessive limb-girdle muscular dystrophy is mapped to 17q11-12. (PubMed id 9245996)9 Moreira E.S....Passos-Bueno M.R. (Am. J. Hum. Genet. 1997)
    841. Progress in myocardial damage detection: new biochemical markers for clinicians. (PubMed id 9055056)9 Mair J. (Crit Rev Clin Lab Sci 1997)
    842. Increase in fetal breech presentation in female carriers of Duchenne muscular dystrophy. (PubMed id 9415684)9 Geifman-Holtzman O....Bianchi D.W. (Am. J. Med. Genet. 1997)
    843. Increased neopterin in patients with chronic and acute coronary syndromes. (PubMed id 9283529)9 Schumacher M....Klein W. (J. Am. Coll. Cardiol. 1997)
    844. Exercise-induced increase in serum interleukin-6 in humans is related to muscle damage. (PubMed id 9130176)9 Bruunsgaard H....Pedersen B.K. (J. Physiol. (Lond.) 1997)
    845. Differential expression of type I cytokeratins in hamster cheek pouch epithelium following treatment with dimethylbenzanthracene. (PubMed id 9416579)9 Shearer B.H....Jenkinson H.F. (amp 1997)
    846. Creatine kinase activity and isoenzymes in lung, colon and liver carcinomas. (PubMed id 9303358)9 Joseph J....Carreras J. (Br. J. Cancer 1997)
    847. [Macroenzymes: an interesting laboratory finding, without clinical relevance]. (PubMed id 9418337)9 Perry C....Eldor A. (Harefuah 1997)
    848. [Generalized gas gangrene infection with rhabdomyloysis following cholecystectomy]. (PubMed id 9163265)9 Haerty W....Briegel J. (Anaesthesist 1997)
    849. Cardiac troponin I levels are normal or minimally elevated after transthoracic cardioversion. (PubMed id 9316538)9 Allan J.J....Jaffe A.S. (J. Am. Coll. Cardiol. 1997)
    850. Creatine kinase subform analysis in hemodialysis patients without acute coronary syndromes. (PubMed id 9226229)9 Robbins M.J....Shah S. (Nephron 1997)
    851. Effect of dietary vitamin E supplementation on the integrity of skeletal muscle in exercised horses. (PubMed id 9250517)9 Siciliano P.D....Lawrence L.M. (J. Anim. Sci. 1997)
    852. Ischemic preconditioning prior to myocardial protection with cold blood cardioplegia in coronary surgery. (PubMed id 9458147)9 Cremer J....Haverich A. (Eur J Cardiothorac Surg 1997)
    853. Creatine kinase MB during myocardial infarction: relationship to preexisting coronary heart disease and medication. (PubMed id 9428940)9 Sax H....Reinhart W.H. (Acta Cardiol 1997)
    854. Pattern of expression of intermediate cytokeratin filaments in the thyroid gland: an immunohistochemical study of simple and stratified epithelial-type cytokeratins. (PubMed id 9099982)9 Fonseca E....Sobrinho-SimA/es M. (Virchows Arch. 1997)
    855. Elevation of serum creatine kinase during treatment with antithyroid drugs in patients with hyperthyroidism due to Graves disease. A novel side effect of antithyroid drugs. (PubMed id 9080924)9 Suzuki S....Hashizume K. (Arch. Intern. Med. 1997)
    856. N-dibenzylphospho-N'-3-(2,6-dichlorophenyl)propyl-guanidine is a bisubstrate-analog for creatine kinase. (PubMed id 9366273)9 Min K.L....Collombel C. (Biochim. Biophys. Acta 1997)
    857. Value of laboratory tests in monitoring acute regional toxicity after isolated limb perfusion. (PubMed id 8985522)9 Vrouenraets B.C....van Dongen J.A. (Ann. Surg. Oncol. 1997)
    858. Glucose and insulin responses to glucagon injection in dairy cows with ketosis and fatty liver. (PubMed id 9465772)9 Steen A....Torjesen P.A. (Zentralbl Veterinarmed A 1997)
    859. Reference data on the anatomy, hematology and biochemistry of 9-month-old silver foxes. (PubMed id 9212520)9 Zhan Y.M....Too K. (Jpn. J. Vet. Res. 1997)
    860. Cardiac release and kinetics of endothelin after severe short-lasting myocardial ischemia. (PubMed id 9316522)9 KrA1ger D....Stierle U. (J. Am. Coll. Cardiol. 1997)
    861. Serum cardiac troponin I, creatine kinase (CK), and CK-MB in early posttraumatic rhabdomyolysis. (PubMed id 9023157)9 Benoist J.F....Edouard A. (Clin. Chem. 1997)
    862. Lumbar muscle rhabdomyolysis after abdominal aortic surgery. (PubMed id 9212115)9 Bertrand M....Coriat P. (Anesth. Analg. 1997)
    863. [Rhabdomyolysis following water intoxication in two schizophrenic patients]. (PubMed id 9453045)9 Kanbayashi T....Hishikawa Y. (No To Shinkei 1997)
    864. [Assessment of regional and systemic toxicity of isolated hyperthermic extremity perfusion with tumor necrosis factor-alpha and melphalan]. (PubMed id 9410682)9 Hohenberger P....Schlag P.M. ( Zeitschrift für alle Gebiete der operativen Medizen 1997)
    865. Thrombolysis-induced coronary reperfusion causes acute and massive interstitial release of cardiac muscle cell proteins. (PubMed id 9059538)9 Cobbaert C....Simoons M.L. (Cardiovasc. Res. 1997)
    866. Skeletal troponin I as a marker of exercise-induced muscle damage. (PubMed id 9338413)9 Sorichter S....Puschendorf B. (J. Appl. Physiol. 1997)
    867. Structure of mitochondrial creatine kinase. (PubMed id 8692275)9 Fritz-Wolf K....Kabsch W. (Nature 1996)
    868. [The elevation of serum creatine kinase in the course of Parkinson disease.--in relation to malignant syndrome]. (PubMed id 8958744)9 Shimoda-Matsubayashi S....Tanabe H. (Rinsho Shinkeigaku 1996)
    869. Variability in serum creatine kinase response after eccentric exercise of the elbow flexors. (PubMed id 8833714)9 Nosaka K. and Clarkson P.M. (Int J Sports Med 1996)
    870. Scavenging effect of Chinonin on NO and oxygen free radicals and its protective effect on the myocardium from the injury of ischemia-reperfusion. (PubMed id 8608170)9 Zhao B....Xin W. (Biochim. Biophys. Acta 1996)
    871. Thrombolytic therapy with urokinase reduces increased circulating endothelial adhesion molecules in acute myocardial infarction. (PubMed id 8821773)9 Squadrito F....Caputi A.P. (Inflamm. Res. 1996)
    872. Serum creatine kinase enzyme levels in the early diagnosis of spermatic cord torsion. (PubMed id 9008324)9 Ulman I....GAPkdemir A. (Urol. Res. 1996)
    873. Metaanalysis of five reported studies on the relation of early coronary patency grades with mortality and outcomes after acute myocardial infarction. (PubMed id 8712096)9 Anderson J.L....Califf R.M. (Am. J. Cardiol. 1996)
    874. Changes of creatine kinase secondary structure induced by the release of nucleotides from caged compounds. An infrared difference-spectroscopy study. (PubMed id 8797846)9 Raimbault C....Vial C. (Eur. J. Biochem. 1996)
    875. Defining the appropriate threshold of creatine kinase elevation after percutaneous coronary interventions. (PubMed id 8644587)9 Abdelmeguid A.E....Topol E.J. (Am. Heart J. 1996)
    876. Early 'rule-in' diagnosis of acute myocardial infarction 4 h post admission for rapid risk stratification by creatine kinase increment (creatine kinase change). (PubMed id 8836388)9 Collinson P.O. and Stubbs P.J. (Ann. Clin. Biochem. 1996)
    877. The role of phosphocreatine kinase in the motility of human spermatozoa supported by different metabolic substrates. (PubMed id 9239671)9 Yeung C.H....Cooper T.G. (Mol. Hum. Reprod. 1996)
    878. Pathophysiological analysis of serum troponin T release kinetics in evolving ischemic myocardial injury. (PubMed id 8803720)9 Seino Y....Hayakawa H. (Jpn. Circ. J. 1996)
    879. Is maternal serum creatine kinase actually a marker for early diagnosis of ectopic pregnancy? (PubMed id 8886676)9 Darai E....Nunez E. (Eur. J. Obstet. Gynecol. Reprod. Biol. 1996)
    880. Fluoroenzymometric method to measure cardiac troponin I in sera of patients with myocardial infarction. (PubMed id 8787705)9 Zaninotto M....Plebani M. (Clin. Chem. 1996)
    881. Effects of strenuous exercise on serum myosin heavy chain fragments in male triathletes. (PubMed id 8814507)9 Prou E....Marini J.F. (Int J Sports Med 1996)
    882. Creatine kinase and creatine kinase-MB release after nontraumatic cardiac arrest. (PubMed id 8610606)9 MA1llner M....Laggner A.N. (Am. J. Cardiol. 1996)
    883. Myocardial troponin T levels in patients with diabetic nephropathy. (PubMed id 8721335)9 Akagi M....Ota Z. (Nihon Jinzo Gakkai Shi 1996)
    884. Factors associated with the release of cardiac troponin T following percutaneous transluminal coronary angioplasty. (PubMed id 8896910)9 Abbas S.A....McKay R.G. (Clin Cardiol 1996)
    885. Enzymatic measurement of creatine in erythrocytes. (PubMed id 8595730)9 Beyer C. and Alting I.H. (Clin. Chem. 1996)
    886. Reduced stretch-reflex sensitivity after exhausting stretch-shortening cycle exercise. (PubMed id 8925809)9 Nicol C....Takala T.E. (Eur J Appl Physiol Occup Physiol 1996)
    887. Cardiac troponin T release into plasma after acute myocardial infarction: only fractional recovery compared with enzymes. (PubMed id 8836389)9 Kragten J.A....van Dieijen-Visser M.P. (Ann. Clin. Biochem. 1996)
    888. Increased creatine kinase brain isoenzyme concentration in cerebrospinal fluid with meningitis. (PubMed id 8829004)9 Nussinovitch M....Nussinovitch A. (Clin Pediatr (Phila) 1996)
    889. Comparison of troponin-T with other cardiac markers in a VA hospital. (PubMed id 8816601)9 Fitzgerald R.L....Herold D.A. (Am. J. Clin. Pathol. 1996)
    890. Creatine kinase is the main target of reactive oxygen species in cardiac myofibrils. (PubMed id 8635232)9 Mekhfi H....Ventura-Clapier R. (Circ. Res. 1996)
    891. Synergic effects of NO and oxygen free radicals in the injury of ischemia-reperfused myocardium--ESR studies on NO free radicals generated from ischemia-reperfused myocardium. (PubMed id 9772352)9 Zhao B....Xin W. (Sci. China, C, Life Sci. 1996)
    892. Serial measurements of serum creatine kinase are of most use in the exclusion of acute myocardial infarction in patients with a history of heart disease. (PubMed id 8937582)9 Johnston J.D. and Harvey C.J. (Ann. Clin. Biochem. 1996)
    893. Perioperative myocardial injury with different modes of antegrade and retrograde cardioplegic delivery. (PubMed id 8664019)9 Neumann F....Wolner E. (Eur J Cardiothorac Surg 1996)
    894. [Dynamic aggregation of thrombocytes in acute myocardial infarct]. (PubMed id 9011739)9 MiriA8 D....KalajziA8 I. (Lijec Vjesn 1996)
    895. Impact of transfusion of mediastinal shed blood on serum levels of cardiac enzymes. (PubMed id 8678628)9 Nguyen Varennes B. (Ann. Thorac. Surg. 1996)
    896. Assessment of selenium and vitamin E deficiencies in dairy herds and clinical disease in calves. (PubMed id 8913012)9 Zust J....SimundiA8 B. (Vet. Rec. 1996)
    897. Superoxide dismutase in human sperm suspensions: relationship with cellular composition, oxidative stress, and sperm function. (PubMed id 8886800)9 Aitken R.J....Irvine D.S. (amp 1996)
    898. Failure of creatine kinase to predict ectopic pregnancy. (PubMed id 8612849)9 Korhonen J....YlAPstalo P. (Fertil. Steril. 1996)
    899. Histogenesis of primary liver carcinomas: strengths and weaknesses of cytokeratin profile and albumin mRNA detection. (PubMed id 8666372)9 D'Errico A....Grigioni W.F. (Hum. Pathol. 1996)
    900. Current incidence and determinants of perioperative myocardial infarction in coronary artery surgery. (PubMed id 8800027)9 Greaves S.C....Antman E.M. (Am. Heart J. 1996)
    901. Daily fluctuations of haematology and blood biochemistry in horses fed varying levels of protein. (PubMed id 8894531)9 Greppi G.F....Pasquini M. (Equine Vet. J. 1996)
    902. Evaluation of serum creatine kinase levels in ectopic pregnancy. (PubMed id 8566277)9 Qasim S.M....Kemmann E. (Fertil. Steril. 1996)
    903. Biochemical changes in three-day-event horses at the beginning, middle and end of Phase C and after Phase D. (PubMed id 8894555)9 Williamson L.H....Green E.M. (Equine Vet J Suppl 1996)
    904. [Acute rhabdomyolysis in status asthmaticus]. (PubMed id 8967096)9 Eisenhuber E....Ratheiser K. (Wien. Klin. Wochenschr. 1996)
    905. Measurement of serum troponin T, creatine kinase MB isoenzyme, and total creatine kinase following arduous physical training. (PubMed id 8830618)9 Collinson P.O....Simmons M.D. (Ann. Clin. Biochem. 1995)
    906. Effect of hypocalcemia on muscle in disorders of calcium metabolism. (PubMed id 7645390)9 Ishikawa T....Watanabe I. ( Overseas edition 1995)
    907. Creatine kinase BB and neuron-specific enolase in cerebrospinal fluid in the diagnosis of brain insult. (PubMed id 7495260)9 VA!zquez M.D....Pounder D.J. (Am J Forensic Med Pathol 1995)
    908. Microtubule stabilization and potentiation of taxol activity by the creatine analog cyclocreatine. (PubMed id 7670140)9 Martin K.J....Kaddurah-Daouk R. (Anticancer Drugs 1995)
    909. Multi-enzyme reference material from established human cell lines and human sources. (PubMed id 7538922)9 Marui Y....Okuda K. ( international journal of clinical chemistry 1995)
    910. Cardiac troponin T release in multiply injured patients. (PubMed id 7493779)9 Mair P....Puschendorf B. (Injury 1995)
    911. [The peak of creatine phosphokinase level in the acute phase of myocardial infarction in patients with and without ischemic precedents]. (PubMed id 7609890)9 Trappolini M....Puletti M. (Minerva Cardioangiol 1995)
    912. Effect of stress on interleukin-2 receptor expression by bovine mononuclear leukocytes. (PubMed id 8746698)9 Lan H.C....Ferguson J.A. (Vet. Immunol. Immunopathol. 1995)
    913. Captopril in acute myocardial infarction. Beneficial effects on infarct size and arrhythmias. (PubMed id 7899404)9 Bussmann W.D....Klepzig H. (Presse Med 1995)
    914. Reduced maximum shortening velocity in the absence of phosphocreatine observed in intact fibres of Xenopus skeletal muscle. (PubMed id 7714829)9 Westerblad H. and LAonnergren J. (J. Physiol. (Lond.) 1995)
    915. Effect of storage on some constituents of camel serum. (PubMed id 8526813)9 Saeed A....Akhtar S. (Aust. Vet. J. 1995)
    916. Effects of electromyostimulation and strength training on muscle soreness, muscle damage and sympathetic activation. (PubMed id 7595984)9 Moreau D....Cometti G. (J Sports Sci 1995)
    917. Biochemical assessment of acute myocardial ischaemia. (PubMed id 7745110)9 Perez-CA!rceles M.D....Luna A. (J. Clin. Pathol. 1995)
    918. Cardiac arrhythmias as a result of intravenous infusions of theophylline in patients with airway obstruction. (PubMed id 7599916)9 Chazan R....Droszcz W. (Int J Clin Pharmacol Ther 1995)
    919. Does a routine operation for intracranial aneurysm incur brain damage? (PubMed id 8561029)9 Rabow L....Zygmunt S. (Acta Neurochir (Wien) 1995)
    920. Leucocytosis as a marker of organ damage induced by chronic strenuous physical exercise. (PubMed id 7671876)9 Kayashima S....Nagata N. (Eur J Appl Physiol Occup Physiol 1995)
    921. Brain regional correspondence between Alzheimer's disease histopathology and biomarkers of protein oxidation. (PubMed id 7595501)9 Hensley K....Carney J.M. (J. Neurochem. 1995)
    922. High early peak creatine kinase after thrombolysis in patients with acute anterior infarction predicts poor left ventricular function. (PubMed id 7585745)9 Freimark D....Rabinowitz B. (Cardiology 1995)
    923. Duchenne muscular dystrophy and idiopathic hyperCKemia segregating in a family. (PubMed id 8533818)9 Frydman M....Shiloh Y. (Am. J. Med. Genet. 1995)
    924. Thyroid status of patients receiving long-term anticonvulsant therapy assessed by peripheral parameters: a placebo-controlled thyroxine therapy trial. (PubMed id 7588456)9 Tiihonen M....VAolimAoki M. (Epilepsia 1995)
    925. Clinical and angiographic correlates of normal creatine kinase with increased MB isoenzymes in possible acute myocardial infarction. (PubMed id 7631598)9 Dorogy M.E....Davis R.C. (Am. Heart J. 1995)
    926. Serum enzyme activities following long-distance running: comparison between Ethiopian and white athletes. (PubMed id 7591698)9 Eliakim A....Shenkman L. (Isr. J. Med. Sci. 1995)
    927. Characteristics and consequences of myocardial infarction after percutaneous coronary intervention: insights from the Coronary Angioplasty Versus Excisional Atherectomy Trial (CAVEAT). (PubMed id 7759725)9 Harrington R.A....Mark D.B. (J. Am. Coll. Cardiol. 1995)
    928. Q wave and Non-Q wave myocardial infarction after thrombolysis. (PubMed id 7594069)9 Matetzky S....Hod H. (J. Am. Coll. Cardiol. 1995)
    929. Iron effects on myocardial enzymes depend on redox state. (PubMed id 8006976)9 KA'rge P. and Campbell K.B. (J. Mol. Cell. Cardiol. 1994)
    930. Cytokeratins in the histological diagnosis of malignant tumors. (PubMed id 7523543)9 Moll R. (Int. J. Biol. Markers 1994)
    931. Immunocytochemical study of epidermal growth factor receptor, transforming growth factor alpha, and &quot;squamous differentiation&quot; in human endometrial carcinoma. (PubMed id 7528164)9 Santini D....Mancini A.M. (Hum. Pathol. 1994)
    932. Cardiac troponin T and CK-MB mass release after visually successful percutaneous transluminal coronary angioplasty in stable angina pectoris. (PubMed id 8273732)9 Ravkilde J....rder M. (Am. Heart J. 1994)
    933. [Comparison of the influence of ipratropium bromide and salbutamol on activity of phosphocreatine kinase (CK) and isoenzyme CK-MB]. (PubMed id 8075616)9 Chazan R....Droszcz W. (Pneumonol Alergol Pol 1994)
    934. Relationship between plasma level of brain natriuretic peptide and myocardial infarct size. (PubMed id 7850823)9 Arakawa N....Hiramori K. (Cardiology 1994)
    935. Muscle biopsy abnormalities in systemic lupus erythematosus: correlation with clinical and laboratory parameters. (PubMed id 8154935)9 Lim K.L....Powell R.J. (Ann. Rheum. Dis. 1994)
    936. Evaluation of creatine analogues as a new class of anticancer agents using freshly explanted human tumor cells. (PubMed id 8145276)9 Martin K.J....Kaddurah-Daouk R. (J. Natl. Cancer Inst. 1994)
    937. Epidermoid cyst of the spleen: a cytokeratin profile with comparison to other squamous epithelia. (PubMed id 7514079)9 Lifschitz-Mercer B....Czernobilsky B. (Virchows Arch. 1994)
    938. Free radical production by activated haem proteins: protective effect of coenzyme Q. (PubMed id 7752822)9 Mordente A....Santini S.A. (Mol. Aspects Med. 1994)
    939. Different time courses of cardiac contractile proteins after acute myocardial infarction. (PubMed id 7704948)9 Mair J....Michel G. ( international journal of clinical chemistry 1994)
    940. Reperfusion reduces left ventricular dilatation by preventing infarct expansion in the acute and chronic phases of myocardial infarction. (PubMed id 8122595)9 Golia G....Zardini P. (Am. Heart J. 1994)
    941. Cytokeratin inclusions in alcoholic liver disease and their relation to the amount of alcohol intake. (PubMed id 7533231)9 Savolainen V.T....Karhunen P.J. (Liver 1994)
    942. Magnetic resonance imaging of skeletal muscles in idiopathic inflammatory myopathies of adults. (PubMed id 8006684)9 Reimers C.D....Vogl T.J. (J. Neurol. 1994)
    943. Serial magnetic resonance imaging in juvenile dermatomyositis--delayed normalization. (PubMed id 7839073)9 Huppertz H.I. and Kaiser W.A. (Rheumatol. Int. 1994)
    944. Indices of training stress during competitive running and swimming seasons. (PubMed id 8163321)9 Flynn M.G....Rodriguez-Zayas J.R. (Int J Sports Med 1994)
    945. Muscle involvement in polyarteritis nodosa: report of a patient presenting clinically as polymyositis and review of the literature. (PubMed id 7914924)9 Fort J.G....Abruzzo J.L. (J. Rheumatol. 1994)
    946. Activity of creatine kinase in a contracting mammalian muscle of uniform fiber type. (PubMed id 7858128)9 McFarland E.W....Moerland T.S. (Biophys. J. 1994)
    947. Timed sequential analysis of creatine kinase in the diagnosis of myocardial infarction in patients over 65 years of age. (PubMed id 7829696)9 Chattington P....Neithercut W.D. (J. Clin. Pathol. 1994)
    948. An equilibrium study of the dependence of secondary and tertiary structure of creatine kinase on subunit association. (PubMed id 7947978)9 Grossman S.H. (Biochim. Biophys. Acta 1994)
    949. [Relationship between early peaking of serum myosin light chain 1 level and washout phenomenon of creatine kinase in acute myocardial infarction]. (PubMed id 8164150)9 Okumachi F....Kato H. (J Cardiol 1994)
    950. Serum enzymes in hypothyroidism. (PubMed id 8078622)9 Burnett J.R....Feek C.M. (N. Z. Med. J. 1994)
    951. Cell cycle studies of cyclocreatine, a new anticancer agent. (PubMed id 7923134)9 Martin K.J....Kaddurah-Daouk R. (Cancer Res. 1994)
    952. Biopsy proven polymyositis in Victoria 1982-1987: analysis of prognostic factors. (PubMed id 8046701)9 Lilley H....Byrne E. (J R Soc Med 1994)
    953. Expression of the mitochondrial creatine kinase genes. (PubMed id 7808456)9 Payne R.M. and Strauss A.W. (Mol. Cell. Biochem. 1994)
    954. Nonparenchymal cell and hepatocellular injury to human liver grafts assessed by enzyme-release into the perfusate. (PubMed id 7934584)9 Rauen Groot H. (Langenbecks Arch Chir 1994)
    955. Changes in serum creatine kinase, lactate dehydrogenase and aldolase activities following supramaximal exercise in athletes. (PubMed id 7967583)9 Karamizrak S.O....AkgA1n N. (J Sports Med Phys Fitness 1994)
    956. Enzymatic activity and morphological differentiation in de novo innervated human muscle cultures. (PubMed id 7524809)9 Meola G....Tremblay J.P. (Eur J Histochem 1994)
    957. Neuroleptic malignant syndrome and mivacurium: a safe alternative to succinylcholine? (PubMed id 7955001)9 Kelly D. and Brull S.J. (Can J Anaesth 1994)
    958. Traumatic rhabdomyolysis from severe beating--experience of volume diuresis in 200 patients. (PubMed id 8064919)9 Knottenbelt J.D. (J Trauma 1994)
    959. Neuromuscular disorder in intensive care unit patients treated with pancuronium bromide. Occurrence in a cluster group of seven patients and two sporadic cases, with electrophysiologic and histologic examination. (PubMed id 8020274)9 Giostra E....Chevrolet J.C. (Chest 1994)
    960. Cyclocreatine (1-carboxymethyl-2-iminoimidazolidine) inhibits the replication of human herpes viruses. (PubMed id 8042860)9 Lillie J.W....Kaddurah-Daouk R. (Antiviral Res. 1994)
    961. [Effect of salbutamol on left ventricular function and selected biochemical parameters in patients with bronchial asthma]. (PubMed id 7854957)9 Chazan R....Droszcz W. (Pol. Arch. Med. Wewn. 1994)
    962. Metabolic and hormonal reactions during training in junior oarsmen. (PubMed id 8262702)9 Steinacker J.M....Stauch M. (Int J Sports Med 1993)
    963. Protective effects of ranolazine in guinea-pig hearts during low-flow ischaemia and their association with increases in active pyruvate dehydrogenase. (PubMed id 8358570)9 Clarke B....McCormack J.G. (Br. J. Pharmacol. 1993)
    964. Usefulness of CKMB and troponin T determinations in patients with acute myocardial infarction complicated by ventricular fibrillation. (PubMed id 8416755)9 Zabel M....Hohnloser S.H. (Clin Cardiol 1993)
    965. [Effect of intravenous infusions of theophylline on cardiac arrhythmias and activity of creatinine kinase CK-MB in patients with airway obstruction]. (PubMed id 8146042)9 Chazan R....Droszcz W. (Pol. Arch. Med. Wewn. 1993)
    966. Adult idiopathic polymyositis without elevation of creatine kinase. Case report and review of the literature. (PubMed id 8480146)9 Gran J.T....Johansen S. (Scand. J. Rheumatol. 1993)
    967. Noninvasive assessment of reperfusion and reocclusion after thrombolysis in acute myocardial infarction. (PubMed id 8279365)9 Klootwijk P....Simoons M.L. (Am. J. Cardiol. 1993)
    968. [Muscular exertion--&quot;embarrassment&quot; in the evaluation of aminotransferases and creatine kinase serum levels]. (PubMed id 8374980)9 Drnek I....Skvor J. (Cesk Pediatr 1993)
    969. Serum enzyme activities in full-term asphyxiated and healthy newborns: enzyme kinetics during the first 144 hours of life. (PubMed id 7916242)9 Lackmann G.M....Mader R. (amp 1993)
    970. Low-dose dobutamine echocardiography detects reversible dysfunction after thrombolytic therapy of acute myocardial infarction. (PubMed id 8339404)9 Smart S.C....Feigenbaum H. (Circulation 1993)
    971. Detection of reperfusion 30 and 60 minutes after coronary recanalization by a rapid new assay of creatine kinase isoforms in acute myocardial infarction. (PubMed id 8438692)9 Abe S....Tahara M. (Am. Heart J. 1993)
    972. Exertional rhabdomyolysis in a patient with calcium adenosine triphosphatase deficiency. (PubMed id 8331362)9 Poels P.J....Joosten E.M. (J. Neurol. Neurosurg. Psychiatr. 1993)
    973. Serum levels of creatine kinase and its isoenzymes during the 1st postpartum day in healthy newborns delivered vaginally or by cesarean section. (PubMed id 8349174)9 Malamitsi-Puchner A....Papas C. (Gynecol. Obstet. Invest. 1993)
    974. Cardiovascular and muscular strain during a tree planting season among British Columbia silviculture workers. (PubMed id 8365392)9 Trites D.G....Banister E.W. (Ergonomics 1993)
    975. Preliminary study of the relationship between plasma and erythrocyte magnesium variations and some circulating pro-oxidant and antioxidant indices in a standardized physical effort. (PubMed id 8292496)9 Laires M.J....Manso C. (Magnes Res 1993)
    976. Decrease in urinary excretion of 3-methylhistidine by patients with Duchenne muscular dystrophy during glucocorticoid treatment. (PubMed id 8482992)9 Kawai H....Saito S. (J. Neurol. 1993)
    977. Diagnostic evaluation of creatine kinase-2 mass and creatine kinase-3 and -2 isoform ratios in early diagnosis of acute myocardial infarction. (PubMed id 8448862)9 Bhayana V....Henderson A.R. (Clin. Chem. 1993)
    978. CSF and serum brain-specific creatine kinase isoenzyme (CK-BB), neuron-specific enolase (NSE) and neural cell adhesion molecule (NCAM) as prognostic markers for hypoxic brain injury after cardiac arrest in man. (PubMed id 8509798)9 KAorkelAo J....Kaukinen S. (J. Neurol. Sci. 1993)
    979. Evidence of plasma CoQ10-lowering effect by HMG-CoA reductase inhibitors: a double-blind, placebo-controlled study. (PubMed id 8463436)9 Ghirlanda G....Littarru G.P. (J Clin Pharmacol 1993)
    980. The role of creatine kinase in the diagnosis of neuroleptic malignant syndrome. (PubMed id 8101383)9 O'Dwyer A.M. and Sheppard N.P. (Psychol Med 1993)
    981. The effect of changes in iron redox state on the activity of enzymes sensitive to modification of SH groups. (PubMed id 8346918)9 Korge P. and Campbell K.B. (Arch. Biochem. Biophys. 1993)
    982. Creatine kinase isoenzyme MB may be elevated in healthy young women after submaximal eccentric exercise. (PubMed id 8340705)9 Miles M.P. and Schneider C.M. (J. Lab. Clin. Med. 1993)
    983. Creatine kinase-MB protein mass is a better indicator for the assessment of acute myocardial infarction in the lower range of creatine kinase level. (PubMed id 8164339)9 Seo H....Hiramori K. (Jpn Heart J 1993)
    984. Temporal creatine kinase curves in acute myocardial infarction. Implications of a good empiric fit with the log-normal function. (PubMed id 8379538)9 Vollmer R.T....Ohman E.M. (Am. J. Clin. Pathol. 1993)
    985. Acute myocardial infarction with papillary muscle rupture. (PubMed id 8416763)9 Hackel D.B. and Wagner G.S. (Clin Cardiol 1993)
    986. Creatine measurement in serum and urine with an automated enzymatic method. (PubMed id 8353946)9 Beyer C. (Clin. Chem. 1993)
    987. Myopathy in the elderly: evaluation of the histopathologic spectrum and the accuracy of clinical diagnosis. (PubMed id 8469346)9 Lacomis D....Smith T.W. (Neurology 1993)
    988. Immunohistochemical analysis of the cytokeratin expression in middle ear cholesteatoma and related epithelial tissues. (PubMed id 1280020)9 Broekaert D....Lane B. (Ann. Otol. Rhinol. Laryngol. 1992)
    989. The first report of a case with acute myocardial infarction showing familial deficiency of creatine kinase. (PubMed id 1504422)9 Shibuya J....Tozawa T. (Intern. Med. 1992)
    990. Effects of combined bezafibrate-simvastatin appraised in healthy subjects. (PubMed id 1587959)9 Horsmans Y....Harvengt C. (J Clin Pharmacol 1992)
    991. Patterns of myoglobin and MM creatine kinase isoforms release early after intravenous thrombolysis or direct percutaneous transluminal coronary angioplasty for acute myocardial infarction, and implications for the early noninvasive diagnosis of reperfusion. (PubMed id 1414933)9 Laperche T....Gourgon R. (Am. J. Cardiol. 1992)
    992. Creatine kinase binding and possible role in chemically skinned guinea-pig taenia coli. (PubMed id 1610872)9 Clark J.F....Ventura-Clapier R. (Biochim. Biophys. Acta 1992)
    993. Evaluation of hypoxic brain injury with spinal fluid enzymes, lactate, and pyruvate. (PubMed id 1541099)9 KAorkelAo J....Harmoinen A. (Crit. Care Med. 1992)
    994. Serum myoglobin and creatine kinase enzymes in acute myocardial infarction treated with Anistreplase. (PubMed id 1597518)9 McCullough D.A....Hillman R.J. (J. Clin. Pathol. 1992)
    995. Myocardial creatine kinase-MB concentration in normal and explanted human hearts and released from hearts of patients with acute myocardial infarction. (PubMed id 1424434)9 van der Laarse A....Bruschke A.V. (Clin Physiol Biochem 1992)
    996. Pathological changes in skeletal muscle in HTLV-I-associated myelopathy. (PubMed id 1506872)9 Inose M....Osame M. (J. Neurol. Sci. 1992)
    997. Creatine kinase MB isoforms for early diagnosis and monitoring of acute myocardial infarction. (PubMed id 1606705)9 Kanemitsu F. and Okigaki T. ( international journal of clinical chemistry 1992)
    998. [Silent exercise-induced enzymatic myopathies at rest in adults. A cause of confusion with fibromyalgia]. (PubMed id 1386455)9 Dupond J.L....Desmurs H. (Presse Med 1992)
    999. Effect of different modalities of exercise and recovery on exercise performance in subjects with sickle cell trait. (PubMed id 1470014)9 Gozal D....Lacour J.R. (Med Sci Sports Exerc 1992)
    1000. Efficacy of cerebro-spinal fluid biochemistry in the diagnosis of brain insult. (PubMed id 1601350)9 Osuna E....Pounder D.J. (Forensic Sci. Int. 1992)
    1001. Effects of isokinetic soreness-inducing exercise on blood levels of C-reactive protein and creatine kinase. (PubMed id 18796751)9 Franklin M.E....Forgione K. (J Orthop Sports Phys Ther 1992)
    1002. Dose/response effects of exercise modeled from training: physical and biochemical measures. (PubMed id 1642735)9 Banister E.W....Fitz-Clarke J. (Ann Physiol Anthropol 1992)
    1003. Cardiac myofibrillar creatine kinase Km is not influenced by contractile protein binding. (PubMed id 1579047)9 Dowell R.T. and Fu M.C. (Life Sci. 1992)
    1004. Effects of recombinant human extracellular-superoxide dismutase type C on myocardial infarct size in pigs. (PubMed id 1505779)9 Hatori N....RydAcn L. (amp 1992)
    1005. Creatine kinase and its MB isoenzyme in the third trimester and the peripartum period. (PubMed id 1460608)9 Leiserowitz G.S....Kost G.J. (J Reprod Med 1992)
    1006. Electrical stimulation-induced changes in skeletal muscle enzymes of men and women. (PubMed id 1331693)9 Gauthier J.M....Simoneau J.A. (Med Sci Sports Exerc 1992)
    1007. Creatine kinase MB isoforms in patients with skeletal muscle injury: ramifications for early detection of acute myocardial infarction. (PubMed id 1458574)9 Wu A.H....OrdA^A+ez-Llanos J. (Clin. Chem. 1992)
    1008. Dermal, serological and CSF changes in amyotrophic lateral sclerosis with and without intrathecal interferon beta treatment. (PubMed id 1506122)9 Westarp M.E....Kornhuber H.H. (Int J Clin Pharmacol Ther Toxicol 1992)
    1009. Serum enzymes activities at rest and after a marathon race. (PubMed id 1434588)9 Nuviala R.J....Giner A. (J Sports Med Phys Fitness 1992)
    1010. Computed tomography of the brain, hepatotoxic drugs and high alcohol consumption in male alcoholic patients and a random sample from the general male population. (PubMed id 1361697)9 MA1tzell S. (Ups. J. Med. Sci. 1992)
    1011. Use of dystrophin genomic and cDNA probes for solving difficulties in carrier detection and prenatal diagnosis of Duchenne muscular dystrophy. (PubMed id 1536162)9 Shomrat R....Shiloh Y. (Am. J. Med. Genet. 1992)
    1012. Molecular analysis of the myoadenylate deaminase deficiencies. (PubMed id 1370861)9 Sabina R.L.... Holmes E.W. (Neurology 1992)
    1013. A clinical evaluation of the effect of calf blood dialysate on the course of acute myocardial infarction. (PubMed id 10148188)9 Moczurad K.W....KrA^l W. (Clin Trials Metaanal 1992)
    1014. Functional coupling to brush border creatine kinase imparts a selective energetic advantage to contractile ring myosin in intestinal epithelial cells. (PubMed id 1531784)9 Gordon P.V. and Keller T.C. (Cell Motil. Cytoskeleton 1992)
    1015. Glycation of human tissue and serum creatine kinase. (PubMed id 1468156)9 Langlois M.R....Leroux-Roels G.G. ( international journal of clinical chemistry 1992)
    1016. Characterization of human cytokeratin 2, an epidermal cytoskeletal protein synthesized late during differentiation. (PubMed id 1380918)9 Collin C.... Franke W.W. (Exp. Cell Res. 1992)
    1017. Alcoholic liver disease. Parenchyma to stroma relationship in fibrosis and cirrhosis as revealed by three-dimensional reconstruction and immunohistochemistry. (PubMed id 1378697)9 Dinges H.P....Mair S. (Am. J. Pathol. 1992)
    1018. Determinants of elevated creatine kinase activity and creatine kinase MB-fraction following cardiopulmonary resuscitation. (PubMed id 1582302)9 Mattana J. and Singhal P.C. (Chest 1992)
    1019. Cardiac enzymes. How to use serial determinations to confirm acute myocardial infarction. (PubMed id 1437917)9 Ruzich R.S. (Postgrad Med 1992)
    1020. Early diagnosis of acute myocardial infarction by CK-MB mass measurements. (PubMed id 1536524)9 Collinson P.O....Greenwood T.W. (Ann. Clin. Biochem. 1992)
    1021. Analytical and clinical evaluation of creatine kinase MB mass assay by IMx: comparison with MB isoenzyme activity and serum myoglobin for early diagnosis of myocardial infarction. (PubMed id 1458571)9 Van Blerk M....Gorus F.K. (Clin. Chem. 1992)
    1022. Prevention of succinylcholine-induced myalgia with lidocaine pretreatment. (PubMed id 15278625)9 Lee T.L. and Aw T.C. (J Anesth 1991)
    1023. [Analysis of CK-MB using immunoinhibition method]. (PubMed id 1762187)9 Sato M. (Rinsho Byori 1991)
    1024. Cardioprotective effects of recombinant human extracellular-superoxide dismutase type C in rat isolated heart subjected to ischemia and reperfusion. (PubMed id 1711638)9 SjAPquist P.O....Abrahamsson T. (J. Cardiovasc. Pharmacol. 1991)
    1025. [Cardiovascular manifestations of hypothyroidism]. (PubMed id 1862565)9 Nyrop M....Haedersdal C. (Ugeskr. Laeg. 1991)
    1026. Effects of 7 successive days of unaccustomed prolonged exercise on aerobic performance and tissue damage in fitness joggers. (PubMed id 2030061)9 Dressendorfer R.H....Timmis G.C. (Int J Sports Med 1991)
    1027. Electrophoresis of serum isoenzymes and proteins following acute myocardial infarction. (PubMed id 1939492)9 Marshall T....Williams K.M. (J. Chromatogr. 1991)
    1028. Dynamics of creatine kinase shuttle enzymes in the human heart. (PubMed id 1909638)9 SylvAcn C....Jansson E. (Eur. J. Clin. Invest. 1991)
    1029. Recovery of monocytes after bone marrow transplantation--rapid reappearance of tumor necrosis factor alpha and interleukin 6 production. (PubMed id 1926348)9 Pechumer H....Ziegler-Heitbrock H.W. (Transplantation 1991)
    1030. Expanded clinical evaluation of lovastatin (EXCEL) study results: IV. Additional perspectives on the tolerability of lovastatin. (PubMed id 1831006)9 Dujovne C.A....Nash D.T. (Am. J. Med. 1991)
    1031. [Analyses of creatine kinase isoforms to detect early diagnosis of reinfarction and reperfusion after acute myocardial infarction]. (PubMed id 2051619)9 Yoneda K....Matsuyama T. (Rinsho Byori 1991)
    1032. Time course of creatine kinase release after termination of sustained ventricular dysrhythmias. (PubMed id 1877446)9 O'Neill P.G....Pacifico A. (Am. Heart J. 1991)
    1033. Estimate of the intrafamilial correlation for serum creatine kinase and pyruvate kinase in females at risk for Duchenne and Becker muscular dystrophies. (PubMed id 1797630)9 Rabbi-Bortolini E....Zatz M. (Hum. Hered. 1991)
    1034. [Cardiac arrest during anesthesia induction with halothane and succinylcholine in an infant. Massive hyperkalemia and rhabdomyolysis in suspected myopathy and/or malignant hyperthermia]. (PubMed id 1952045)9 Mehler J....Wolpers K. (Anaesthesist 1991)
    1035. Oxygen metabolite effects on creatine kinase and cardiac energetics after reperfusion. (PubMed id 1877684)9 Banerjee A....Whitman G.J. (Am. J. Physiol. 1991)
    1036. Cytokeratin expression patterns in metastatic transitional cell carcinoma of the urinary tract. An immunohistochemical study comparing local tumor and autologous metastases. (PubMed id 1721491)9 Schaafsma H.E....Ruiter D.J. (Am. J. Pathol. 1991)
    1037. Lactate dehydrogenase, creatine kinase, and their isoenzymes in pleural effusions. (PubMed id 1934463)9 Paavonen T....Kiistala U. (Clin. Chem. 1991)
    1038. Increase in serum myoglobin, creatine kinase, and free fatty acids, during recovery from a paralytic attack in hypokalemic periodic paralysis. (PubMed id 1660381)9 De Keyser J....Ebinger G. (Clin Neurol Neurosurg 1991)
    1039. [The clinico-diagnostic significance of determining creatine kinase activity and isoenzymes in patients with systemic lupus erythematosus]. (PubMed id 1948334)9 ZborovskiA- A.B....Nuruzzaman M. (Sov Med 1991)
    1040. [Cyclic AMP content, protein kinase activity, and DNA structure in resting and proliferating peripheral blood lymphocytes and in human T-lymphoma cells]. (PubMed id 1667447)9 Moskaleva E.I.u. and Grozdova I.D. (Vopr. Med. Khim. 1991)
    1041. Tissue plasminogen activator in refractory unstable angina. A randomized double-blind placebo-controlled trial in patients with refractory unstable angina and subsequent angioplasty. (PubMed id 1782951)9 van den Brand M....Simoons M.L. (Eur. Heart J. 1991)
    1042. Immunohistochemical study of creatine kinase isozymes in the human upper limb bud. (PubMed id 1950416)9 Shinohara H....Kato K. (Acta Anat (Basel) 1991)
    1043. [A case of BehAset's disease associated with myopathy during cyclosporin treatment]. (PubMed id 1764861)9 Shibata K....Maruyama S. (Rinsho Shinkeigaku 1991)
    1044. Serum chemistry alterations, including creatine kinase isoenzymes, in furazolidone toxicosis of ducklings: preliminary findings. (PubMed id 1785996)9 Webb D.M....Van Vleet J.F. (Avian Dis. 1991)
    1045. Automated determination of creatine kinase activity in serum with use of thermostable glucokinase. (PubMed id 2004455)9 Maeda I....Miyai K. (Clin. Chem. 1991)
    1046. Influence of coronary collateral vessels on myocardial infarct size in humans. Results of phase I thrombolysis in myocardial infarction (TIMI) trial. The TIMI Investigators. (PubMed id 1900223)9 Habib G.B....Bolli R. (Circulation 1991)
    1047. Molecular diversity of cytokeratins: significance for cell and tumor differentiation. (PubMed id 1725827)9 Moll R. (Acta Histochem. Suppl. 1991)
    1048. Familial myopathy with elevated serum angiotensin-converting enzyme, creatine kinase and lactate dehydrogenase isoenzyme 5. (PubMed id 1655986)9 Henze T....Reichmann H.R. (J. Neurol. 1991)
    1049. Creatine kinase and prostaglandin E2 release from isolated Duchenne muscle. (PubMed id 1845917)9 Jackson M.J....Edwards R.H. (Neurology 1991)
    1050. Assessment of coronary artery patency after thrombolytic therapy: accurate prediction utilizing the combined analysis of three noninvasive markers. (PubMed id 2050939)9 Hohnloser S.H....Just H. (J. Am. Coll. Cardiol. 1991)
    1051. [Heart injury caused by air shock wave trauma]. (PubMed id 2046229)9 Leksowski K....Barcikowski S. (Kardiol Pol 1991)
    1052. Incidence and clinical significance of transient creatine kinase elevations and the diagnosis of non-Q wave myocardial infarction associated with coronary angioplasty. (PubMed id 1993778)9 Klein L.W....Lesch M. (J. Am. Coll. Cardiol. 1991)
    1053. High creatine kinase (CK) levels. (PubMed id 2030419)9 (J Occup Med 1991)
    1054. Early detection of acute myocardial infarction by measurement of mass concentration of creatine kinase-MB. (PubMed id 1746453)9 Mair J....Puschendorf B. (Am. J. Cardiol. 1991)
    1055. [The clinical and prognostic significance of the infarct size in patients discharged after a myocardial infarct]. (PubMed id 1790538)9 Finocchi G....Vincenzi M. (Cardiologia 1991)
    1056. Kinetic analyses of creatine kinase release patterns in patients with acute myocardial infarction undergoing emergency coronary arteriography. (PubMed id 2232111)9 Horie M....Kawai C. (Jpn. Circ. J. 1990)
    1057. Muscle enzymes and isoenzymes in Emery-Dreifuss muscular dystrophy. (PubMed id 2311208)9 Bialer M.G....Kelly T.E. (Clin. Chem. 1990)
    1058. Resistance exercise effects on plasma cortisol, testosterone and creatine kinase activity in anabolic-androgenic steroid users. (PubMed id 2228359)9 Boone J.B....Andres F.F. (Int J Sports Med 1990)
    1059. [Assessment of prognosis in acute myocardial infarct after reaching the maximum enzyme activity]. (PubMed id 2378131)9 Junker L....Heine H. (Z Gesamte Inn Med 1990)
    1060. The theory of diazymes and functional coupling of pyruvate kinase and creatine kinase. (PubMed id 2385106)9 Dillon P.F. and Clark J.F. (J. Theor. Biol. 1990)
    1061. Regional variations in the expression of cytokeratin proteins in the adult human cochlea. (PubMed id 1693521)9 Anniko M....Pfaltz C.R. (Eur Arch Otorhinolaryngol 1990)
    1062. Beneficial effect of intravenous nitroglycerin in patients with non-Q myocardial infarction. (PubMed id 2115819)9 Charvat Amad H. (Cardiologia 1990)
    1063. An evaluation of cocaine-induced chest pain. (PubMed id 2221513)9 Tokarski G.F....Tomlanovich M.C. (Ann Emerg Med 1990)
    1064. Assay of serum cardiac myosin heavy chain fragments in patients with acute myocardial infarction: determination of infarct size and long-term follow-up. (PubMed id 2220532)9 LAcger J.O....Peperstraete B. (Am. Heart J. 1990)
    1065. Serum parvalbumin, an indicator of muscle disease in murine dystrophy and myotonia. (PubMed id 2366828)9 Jockusch H....Zippel M. (amp 1990)
    1066. The effective use of cardiac enzymes and electrocardiograms in the diagnosis of acute myocardial infarction in the elderly. (PubMed id 2371189)9 Gama R....Buckley B.M. (Postgrad Med J 1990)
    1067. Selective beta-adrenoceptor partial agonist effects of pindolol and xamoterol on skeletal muscle assessed by plasma creatine kinase changes in healthy subjects. (PubMed id 1980200)9 Tomlinson B....Prichard B.N. (Br J Clin Pharmacol 1990)
    1068. Alterations in serum creatine kinase and lactate dehydrogenase. Association with abdominal aortic surgery, myocardial infarction and bowel necrosis. (PubMed id 2306954)9 Graeber G.M....Rich N.M. (Chest 1990)
    1069. Correlation between tests of muscle involvement and clinical muscle weakness in polymyositis and dermatomyositis. (PubMed id 2088650)9 Tymms K.E....Buchanan W.W. (Clin. Rheumatol. 1990)
    1070. Carnitine palmitoyltransferase deficiency: a common cause of recurrent myoglobinuria. (PubMed id 2228562)9 Sadeh M. and Gutman A. (Isr. J. Med. Sci. 1990)
    1071. [The enhanced relative intensity of cAMP-dependent protein phosphorylation in stomach tumors]. (PubMed id 2169140)9 Grozdova I.D....Severin E.S. (Vopr Onkol 1990)
    1072. Monoclonal antibody inhibiting creatine kinase MM3 but not isoform MM1. (PubMed id 2297910)9 Suzuki T....Murachi T. (Clin. Chem. 1990)
    1073. Testosterone, cortisol, and creatine kinase levels in male distance runners during reduced training. (PubMed id 2180832)9 Houmard J.A....Burns J.M. (Int J Sports Med 1990)
    1074. Mass concentration and activity concentration of creatine kinase isoenzyme MB compared in serum after acute myocardial infarction. (PubMed id 2404640)9 Delanghe J.R....Wieme R.J. (Clin. Chem. 1990)
    1075. Rapid diagnosis of myocardial infarction and reperfusion by assay of plasma isoforms of creatine kinase isoenzymes. (PubMed id 2253334)9 Abendschein D.R. (Clin. Biochem. 1990)
    1076. heterogeneity of creatine kinase isoenzyme MM in serum in myocardial infarction: interconversion of the &quot;normal&quot; and &quot;abnormal&quot; sub-bands by glutathione. (PubMed id 2337989)9 Williams J....Marshall T. (Clin. Chem. 1990)
    1077. [Clinical significance of serum cardiac myosin light chain I in patients with muscular dystrophy]. (PubMed id 2253417)9 Saitoh M....Takakura H. (Rinsho Shinkeigaku 1990)
    1078. A two-tube immunochemical method for determination of CK-MB isoenzyme in serum evaluated. (PubMed id 2178803)9 Panteghini M....Pagani F. (Clin. Chem. 1990)
    1079. Diagnosis of perioperative myocardial infarction by considering relationship of postoperative electrocardiogram changes and enzyme increases after coronary bypass operation. (PubMed id 2357826)9 Griesmacher A....MA1ller M.M. (Clin. Chem. 1990)
    1080. Immunohistochemical interpretation of early epithelial disorders of pyriform sinus. (PubMed id 1699466)9 Murakami Y. and Saito Y. (Ann. Otol. Rhinol. Laryngol. 1990)
    1081. Interleukin-1 alpha, interleukin-2, and soluble interleukin-2 receptors in polymyositis. (PubMed id 2369417)9 Wolf R.E. and Baethge B.A. (Arthritis Rheum. 1990)
    1082. [McArdle's disease without typical symptoms]. (PubMed id 2085931)9 Watanabe M....Hirai S. (Rinsho Shinkeigaku 1990)
    1083. Cardiac enzyme changes in elderly fallers. (PubMed id 2363384)9 Swain D.G....Buckley B.M. (Age Ageing 1990)
    1084. An immunochemical procedure for determination of creatine kinase 3(1) (serum-specific) isoform in human serum evaluated. (PubMed id 2372936)9 Panteghini M....Alebardi O. (Clin. Biochem. 1990)
    1085. Serum aldolase with creatine kinase in current clinical practice. (PubMed id 2102148)9 Tormey W.P. (Br J Clin Pract 1990)
    1086. [Enzyme liberation after electrical His bundle ablation]. (PubMed id 2378136)9 Junker L....Pech H. (Z Gesamte Inn Med 1990)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 1120 HGNC: 1938 AceView: CHKB Ensembl:ENSG00000100288 euGenes: HUgn1120
    ECgene: CHKB Kegg: 1120 H-InvDB: CHKB

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    PharmGKB entry for CHKB Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CHKB gene:
    Search GeneIP for patents involving CHKB

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, GeneTex, and/or others, Clones from OriGene, GenScript, Sino Biological, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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    CRISPR knockouts from OriGene)
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