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CHID1 Gene

protein-coding   GIFtS: 51
GCID: GC11M000859

Chitinase Domain Containing 1

  Search for CHID1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Chitinase Domain Containing 11 2
Stabilin-1-Interacting Chitinase-Like Protein2 3
SI-CLP2 3
SICLP2 5
Chitinase Domain-Containing Protein 12
Stabilin-1 Interacting Chitinase-Like Protein2

External Ids:    HGNC: 284741   Entrez Gene: 660052   Ensembl: ENSG000001778307   OMIM: 6156925   UniProtKB: Q9BWS93   

Export aliases for CHID1 gene to outside databases

Previous GC identifer: GC11M000683


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CHID1 Gene:
CHID1 (chitinase domain containing 1) is a protein-coding gene. GO annotations related to this gene include chitinase activity.

UniProtKB/Swiss-Prot: CHID1_HUMAN, Q9BWS9
Function: Saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin
neutralization. Ligand-binding specificity relates to the length of the oligosaccharides, with preference for
chitotetraose (in vitro)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NT_009237.19  NC_018922.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CHID1 gene promoter:
         MAZR   p53   Arnt   Meis-1b   Gfi-1   Meis-1a   Meis-1   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCHID1 promoter sequence
   Search Chromatin IP Primers for CHID1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CHID1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.5   Ensembl cytogenetic band:  11p15.5   HGNC cytogenetic band: 11p15.5

CHID1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CHID1 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M000859:  view genomic region     (about GC identifiers)

Start:
867,357 bp from pter      End:
915,058 bp from pter
Size:
47,702 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CHID1_HUMAN, Q9BWS9 (See protein sequence)
Recommended Name: Chitinase domain-containing protein 1 precursor  
Size: 393 amino acids; 44941 Da
Subunit: Interacts with STAB1
1 PDB 3D structure from and Proteopedia for CHID1:
3BXW (3D)    
Secondary accessions: B3KWB0 Q8NBM9 Q96CZ3 Q96S93 Q96SK0 Q9BY52
Alternative splicing: 3 isoforms:  Q9BWS9-1   Q9BWS9-2   Q9BWS9-3   

Explore the universe of human proteins at neXtProt for CHID1: NX_Q9BWS9

Explore proteomics data for CHID1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys361
  • Modification sites at PhosphoSitePlus

  • See CHID1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (5 alternative transcripts): 
    NP_001136146.1  NP_001136147.1  NP_001136148.1  NP_001136149.1  NP_076436.3  

    ENSEMBL proteins: 
     ENSP00000433879   ENSP00000431169   ENSP00000325055   ENSP00000431356   ENSP00000416034  
     ENSP00000435503   ENSP00000388156   ENSP00000435336   ENSP00000434651   ENSP00000432697  
     ENSP00000432431   ENSP00000436017   ENSP00000435731   ENSP00000436752   ENSP00000433570  
     ENSP00000435607   ENSP00000431766   ENSP00000324821   ENSP00000391255   ENSP00000398722  
     ENSP00000338838  

    CHID1 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for CHID1

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR011583 Chitinase_II
     IPR017853 Glycoside_hydrolase_SF
     IPR001223 Glyco_hydro18cat
     IPR013781 Glyco_hydro_catalytic_dom

    Graphical View of Domain Structure for InterPro Entry Q9BWS9

    ProtoNet protein and cluster: Q9BWS9

    UniProtKB/Swiss-Prot: CHID1_HUMAN, Q9BWS9
    Similarity: Belongs to the glycosyl hydrolase 18 family


    Find genes that share domains with CHID1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CHID1_HUMAN, Q9BWS9
    Function: Saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin
    neutralization. Ligand-binding specificity relates to the length of the oligosaccharides, with preference for
    chitotetraose (in vitro)
    Induction: Up-regulated by IL4/interleukin-4 and dexamethasone in the macrophages. Up-regulated by glucocorticoid

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004553hydrolase activity, hydrolyzing O-glycosyl compounds ----
    GO:0004568chitinase activity IEA--
    GO:0005515protein binding IPI16357325
    GO:0070492oligosaccharide binding IPI--
         
    Find genes that share ontologies with CHID1           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for CHID1:
     Decreased circadian period len  Decreased viability with cispl 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CHID1
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CHID1_HUMAN, Q9BWS9: Secreted. Lysosome
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    lysosome5
    vacuole5
    golgi apparatus2
    mitochondrion2
    cytosol1
    endosome1
    peroxisome1

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region ----
    GO:0005615extracellular space IDA16357325
    GO:0005764lysosome IDA16357325
    GO:0005770late endosome IDA16357325
    GO:0005802trans-Golgi network IDA16357325

    Find genes that share ontologies with CHID1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CHID1
    Interactions:

        Search GeneGlobe Interaction Network for CHID1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for CHID1 (Q9BWS93 ENSP000003388384) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    STAB1Q9NY153, ENSP000003129464I2D: score=1 STRING: ENSP00000312946
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process IEA--
    GO:0006032chitin catabolic process IEA--
    GO:0045087innate immune response IEA--
    GO:1900016negative regulation of cytokine production involved in inflammatory response IDA--

    Find genes that share ontologies with CHID1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CHID1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CHID1 gene (5 alternative transcripts): 
    NM_001142674.1  NM_001142675.1  NM_001142676.1  NM_001142677.1  NM_023947.3  

    Unigene Cluster for CHID1:

    Chitinase domain containing 1
    Hs.144468  [show with all ESTs]
    Unigene Representative Sequence: NM_001142675
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 26):
    ENST00000532909 ENST00000529539 ENST00000323578 ENST00000534207 ENST00000429789
    ENST00000528581 ENST00000436108 ENST00000524538 ENST00000528521 ENST00000526714
    ENST00000528534 ENST00000524832 ENST00000531010 ENST00000531859 ENST00000534254
    ENST00000528426 ENST00000533056 ENST00000533059
    miRNA
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    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CHID1
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    GenScript: all cDNA clones in your preferred vector (see all 5): CHID1 (NM_001142677)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHID1
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      QuantiTect SYBR Green Assays in human, mouse, rat CHID1
      QuantiFast Probe-based Assays in human, mouse, rat CHID1

    Additional mRNA sequence: 

    AF212229.1 AK027711.1 AK075413.1 AK124697.1 AK225025.1 AK225398.1 AK297743.1 AK301245.1 
    AY037151.1 BC000001.2 BC013642.1 BC095409.1 

    22 DOTS entries:

    DT.100038265  DT.116819  DT.97818425  DT.100826012  DT.100800785  DT.95263817  DT.100826007  DT.92446358 
    DT.100826000  DT.100826015  DT.100826004  DT.100840054  DT.101963528  DT.120699221  DT.95259504  DT.120699223 
    DT.100826001  DT.100826003  DT.120699214  DT.120699254  DT.95259496  DT.95259513 

    Selected AceView cDNA sequences (see all 355):

    BM807794 AV647073 BM726287 AI184854 BX397399 BU680477 CF130423 AI474457 
    BC000001 AV655765 BQ934003 AA563856 CA396681 BM821290 BU501790 BQ006128 
    AW827234 BQ000149 BM720274 AI815918 BG674293 AF212229 BM924291 BU624700 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CHID1 (see all 9)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b · 12c ^ 13 ^ 14a · 14b ^ 15 ^ 16a · 16b · 16c
    SP1:              -                                   -                                                     -     -     -                                 
    SP2:                          -                       -                                                     -     -     -                                 
    SP3:              -           -                       -                                                     -     -     -                                 
    SP4:                                                                                                                                                      
    SP5:              -           -                                                                                                                           


    ECgene alternative splicing isoforms for CHID1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CHID1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGTGAGTGA
    CHID1 Expression
    About this image

    CHID1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CHID1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.144468

    UniProtKB/Swiss-Prot: CHID1_HUMAN, Q9BWS9
    Tissue specificity: Expressed in cells of monocytic, T, B and epithelial origin

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHID1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CHID1 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Chid11 , 5 chitinase domain containing 11, 5 86.77(n)1
    89.82(a)1
      7 (86.86 cM)5
    680381  NM_001142681.11  NP_001136153.11 
     1414931365 
    chicken
    (Gallus gallus)
    Aves CHID11 chitinase domain containing 1 66.33(n)
    66.92(a)
      423103  NM_001199634.1  NP_001186563.1 
    lizard
    (Anolis carolinensis)
    Reptilia CHID16
    chitinase domain containing 1
    66(a)
    1 ↔ 1
    1(72568120-72701121)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ079988.12   -- 81.64(n)    BJ079988.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb02e072 wufb02e07 74.09(n)   337225  BC054696.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG84601 CG8460 51.79(n)
    42.78(a)
      34115  NM_135346.4  NP_609190.2 
    worm
    (Caenorhabditis elegans)
    Secernentea chil-106
    chil-146
    Protein R09B5.12 (R09B5.12) mRNA, complete cds
    27(a)
    21(a)
    many → 1
    many → 1
    X(957886-960567) WBGene00016642
    V(1455062-1456646) WBGene00019980
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G010401 AT4G01040 49.95(n)
    40.52(a)
      827924  NM_116334.3  NP_192013.1 
    rice
    (Oryza sativa)
    Liliopsida Os01g06198001 Os01g0619800 49.77(n)
    42.72(a)
      4326620  NM_001050131.1  NP_001043596.1 


    ENSEMBL Gene Tree for CHID1 (if available)
    TreeFam Gene Tree for CHID1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CHID1 gene
    Selected SIMAP similar genes for CHID1 using alignment to 15 protein entries:     CHID1_HUMAN (see all proteins) (see all similar genes):
    DCTN5    NF2    C18orf8    CFLAR    CTSS    LYRM4
    LAMB4    ZNF461    ZNF738    DYM    FAM175A    PKN1
    UBIAD1    ZNF20    ZNF212    ATP6V0A1    ERBB2    LINC00596

    Find genes that share paralogs with CHID1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CHID1 (see all 1025)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs283763571,2
    C--867621(+) AAAAAC/AAAAGT 5 -- int12Minor allele frequency- A:0.00NA WA 4
    rs1510066221,2
    --867676(+) CTGCCA/TGCCTT 5 -- int10--------
    rs1174037821,2
    F--867813(+) TTGTTC/GCTAGA 5 -- int11Minor allele frequency- G:0.02NA 120
    rs49632061,2
    C,F,A,H--867824(-) AGGGGC/TAGAGT 5 -- int121Minor allele frequency- N:0.00EA NA NS WA 2532
    rs1179742651,2
    F--867855(+) AAGCAC/TCTGTC 5 -- int11Minor allele frequency- T:0.03NA 120
    rs1396483661,2
    --868271(+) AGCTTA/GTGTTT 5 -- ut310--------
    rs1838861921,2
    C--868385(+) GCACAG/TGCCAC 5 -- ut310--------
    rs1496596511,2
    --868392(+) CCACCA/GTGTCT 5 -- ut310--------
    rs1112894211,2
    C--868402(+) TTGCTT/AATTTT 5 -- ut311Minor allele frequency- A:0.50CSA 2
    rs32017641,2
    C--868410(-) aaaatA/Ggaaaa 5 -- ut310--------

    HapMap Linkage Disequilibrium report for CHID1 (867357 - 915058 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for CHID1 (see all 25):    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv182e199CNV Deletion23128226
    esv2663667CNV Deletion23128226
    esv2671662CNV Deletion23128226
    esv2743879CNV Deletion23290073
    esv2743880CNV Deletion23290073
    esv2743878CNV Deletion23290073
    esv2669189CNV Deletion23128226
    esv1667682CNV Insertion17803354
    nsv832044CNV Loss17160897
    nsv469923CNV Loss18288195

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CHID1
    DNA2.0 Custom Variant and Variant Library Synthesis for CHID1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 615692    OMIM disorders: --


    Find genes that share disorders with CHID1           About GenesLikeMe

    Genetic Association Database (GAD): CHID1
    Human Genome Epidemiology (HuGE) Navigator: CHID1 (1 document)

    Export disorders for CHID1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CHID1 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with CHID1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. Structure of human stabilin-1 interacting chitinase-like protein (SI- CLP) reveals a saccharide-binding cleft with lower sugar-binding selectivity. (PubMed id 20724479)1, 2 Meng G.... Zheng X. (J. Biol. Chem. 2010)
    3. Novel stabilin-1 interacting chitinase-like protein (SI-CLP) is up- regulated in alternatively activated macrophages and secreted via lysosomal pathway. (PubMed id 16357325)1, 2 Kzhyshkowska J.... Goerdt S. (Blood 2006)
    4. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (DNA Res. 2005)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. New paralogues and revised time line in the expansion of the vertebrate GH18 family. (PubMed id 23558346)1 Hussain M. and Wilson J.B. (J. Mol. Evol. 2013)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    9. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    10. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 66005 HGNC: 28474 AceView: MGC3234 Ensembl:ENSG00000177830 euGenes: HUgn66005
    ECgene: CHID1 H-InvDB: CHID1

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for CHID1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for CHID1 gene:
    Search GeneIP for patents involving CHID1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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