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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CHIC1 Gene

protein-coding   GIFtS: 40
GCID: GC0XP072782

Cysteine-Rich Hydrophobic Domain 1

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Cysteine-Rich Hydrophobic Domain 11 2
Brain X-Linked Protein2 3
BRX2 3
Cystein-Rich Hydrophobic Domain 12
Cysteine-Rich Hydrophobic Domain 1 Protein2

External Ids:    HGNC: 19341   Entrez Gene: 533442   Ensembl: ENSG000002041167   UniProtKB: Q5VXU33   

Export aliases for CHIC1 gene to outside databases

Previous GC identifers: GC0XP068596 GC0XP069957 GC0XU900457 GC0XP072566 GC0XP072699 GC0XP066415


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for CHIC1 Gene: 
CHIC1 (cysteine-rich hydrophobic domain 1) is a protein-coding gene. Diseases associated with CHIC1 include leukemia. An important paralog of this gene is CHIC2.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NT_011669.17  NC_018934.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CHIC1 gene promoter:
         POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   Nkx2-5   POU3F2   Gfi-1   HNF-1A   N-Myc   FAC1   HNF-1   Pax-4a   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for CHIC1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHIC1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq13.2   Ensembl cytogenetic band:  Xq13.2   HGNC cytogenetic band: Xq13.2

CHIC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CHIC1 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP072782:  view genomic region     (about GC identifiers)

Start:
72,782,984 bp from pter      End:
72,906,937 bp from pter
Size:
123,954 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CHIC1_HUMAN, Q5VXU3 (See protein sequence)
Recommended Name: Cysteine-rich hydrophobic domain 1 protein  
Size: 224 amino acids; 25616 Da
Subcellular location: Cell membrane (By similarity). Cytoplasmic vesicle (By similarity). Note=Also present at a
Golgi-like vesicular compartment and at scattered vesicles (By similarity)
Caution: It is uncertain whether Met-1 or Met-8 is the initiator
Secondary accessions: A0PJZ2 B0QZ87 B9EGS5 Q5CZ84
Alternative splicing: 2 isoforms:  Q5VXU3-1   Q5VXU3-2   

Explore the universe of human proteins at neXtProt for CHIC1: NX_Q5VXU3

Explore proteomics data for CHIC1 at MOPED 

Post-translational modifications:

  • UniProtKB: Palmitoylated (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q5VXU3

  • CHIC1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CHIC1 Protein Expression
    REFSEQ proteins: NP_001034929.2  
    ENSEMBL proteins: 
     ENSP00000362603   ENSP00000362601   ENSP00000432985   ENSP00000473482  

    Human Recombinant Protein Products for CHIC1: 
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    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for CHIC1
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for CHIC1
    GenScript Custom Purified and Recombinant Proteins Services for CHIC1
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CHIC1 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--
    GO:0016023cytoplasmic membrane-bounded vesicle IEA--

    CHIC1 for ontologies           About GeneDecksing



    CHIC1 Antibody Products: 
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    LSBio Antibodies in human, mouse, rat for CHIC1 

    Assay Products for CHIC1: 
    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for CHIC1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CHIC1 
    Cloud-Clone Corp. CLIAs for CHIC1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR019383 Golgin_A_7/ERF4

    Graphical View of Domain Structure for InterPro Entry Q5VXU3

    ProtoNet protein and cluster: Q5VXU3

    UniProtKB/Swiss-Prot: CHIC1_HUMAN, Q5VXU3
    Similarity: Belongs to the CHIC family


    CHIC1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Chic1):
     normal 

    CHIC1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for CHIC1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CHIC1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CHIC1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CHIC1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CHIC1
    8/168 QIAGEN miScript miRNA Assays for microRNAs that regulate CHIC1 (see all 168):
    hsa-miR-411* hsa-miR-576-3p hsa-miR-106a hsa-miR-128 hsa-miR-134 hsa-miR-519a hsa-miR-3916 hsa-miR-3622b-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CHIC1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CHIC1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CHIC1
    Sirion Biotech Customized adenovirus for overexpression of CHIC1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for CHIC1 (see all 6)
    OriGene ORF clones in mouse, rat for CHIC1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CHIC1 (NM_001039840)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CHIC1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHIC1
    Sirion Biotech Customized lentivirus for stable overexpression of CHIC1 
                         Customized lentivirus expression plasmids for stable overexpression of CHIC1 

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for CHIC1
    Search LifeMap BioReagents cell lines for CHIC1
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHIC1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CHIC1

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for CHIC1 (ENSP000003626014) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CHIC1

    Search CenterWatch for drugs/clinical trials and news about CHIC1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CHIC1 gene: 
    NM_001039840.2  

    Unigene Cluster for CHIC1:

    Cysteine-rich hydrophobic domain 1
    Hs.496323  [show with all ESTs]
    Unigene Representative Sequence: NM_001039840
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373504 ENST00000373502(uc004ebk.4 uc010nlo.3 uc004ebl.4 uc011mql.2)
    ENST00000498407 ENST00000498318
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CHIC1
    8/168 QIAGEN miScript miRNA Assays for microRNAs that regulate CHIC1 (see all 168):
    hsa-miR-411* hsa-miR-576-3p hsa-miR-106a hsa-miR-128 hsa-miR-134 hsa-miR-519a hsa-miR-3916 hsa-miR-3622b-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CHIC1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CHIC1
    Clone
    Products:
         
    OriGene clones in human, mouse for CHIC1 (see all 6)
    OriGene ORF clones in mouse, rat for CHIC1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CHIC1 (NM_001039840)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CHIC1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHIC1
    Sirion Biotech Customized lentivirus for stable overexpression of CHIC1 
                         Customized lentivirus expression plasmids for stable overexpression of CHIC1 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for CHIC1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CHIC1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHIC1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHIC1

    Additional mRNA sequence: 

    AK057786.1 AK295903.1 AK297768.1 AL832095.1 BC050300.1 BC127727.1 BC127728.1 BC136691.1 
    BC136692.1 CR627010.1 CR936642.1 Y11897.1 

    5 DOTS entries:

    DT.121295095  DT.109408  DT.100748111  DT.121295072  DT.91907317 

    24/46 AceView cDNA sequences (see all 46):

    AI580377 CB044853 AI745136 BC050300 BU166259 AI017400 AA581996 AA918471 
    CR627010 BU520824 N90842 AW268816 AK057786 CB044854 AI080742 AL832095 
    BI918113 Y11897 AV700331 AA062610 BX508030 BI439741 CA867185 BF038278 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CHIC1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CATCTTGCAT
    CHIC1 Expression
    About this image


    See CHIC1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CHIC1

    SOURCE GeneReport for Unigene cluster: Hs.496323

    UniProtKB/Swiss-Prot: CHIC1_HUMAN, Q5VXU3
    Tissue specificity: Equally expressed in various parts of the brain

        SABiosciences Custom PCR Arrays for CHIC1
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for CHIC1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CHIC1
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHIC1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHIC1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for CHIC1 gene from 6/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Chic11 , 5 cysteine-rich hydrophobic domain 11, 5 90.95(n)1
    97.29(a)1
      X (46.08 cM)5
    122121  NM_009767.21  NP_033897.11 
     1033564765 
    chicken
    (Gallus gallus)
    Aves CHIC11 cysteine-rich hydrophobic domain 1 82.98(n)
    86.17(a)
      422318  NM_001031122.1  NP_001026293.1 
    lizard
    (Anolis carolinensis)
    Reptilia CHIC16
    Uncharacterized protein
    79(a)
    1 ↔ 1
    GL343735.1(233241-245329)
    zebrafish
    (Danio rerio)
    Actinopterygii chic11 cysteine-rich hydrophobic domain 1 77.07(n)
    89.6(a)
      564524  NM_001201463.1  NP_001188392.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG59383   -- 58(a)   97F1   --
    worm
    (Caenorhabditis elegans)
    Secernentea tag-2661 Protein TAG-266 51.22(n)
    47.46(a)
      175219  NM_064826.2  NP_497227.1 


    ENSEMBL Gene Tree for CHIC1 (if available)
    TreeFam Gene Tree for CHIC1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CHIC1 gene
    CHIC22  
    1 SIMAP similar gene for CHIC1 using alignment to 3 protein entries:     CHIC1_HUMAN (see all proteins):
    CHIC2

    CHIC1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1486 SNPs in CHIC1 are shown (see all 1486)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs24867801,2
    H--72784976(+) CACGGT/GTTTAC 1 -- int14Minor allele frequency- G:0.00NS EA 418
    rs1891545451,2
    --72785459(+) AATGTC/TTTGGG 1 -- int10--------
    rs1814911101,2
    --72785585(+) AATCTC/TATTCT 1 -- int10--------
    rs120101561,2
    C,F,H--72785630(+) TTTCTG/CGCATA 1 -- int15Minor allele frequency- C:0.14NS EA NA 420
    rs1856906751,2
    --72785636(+) GCATAC/GGAGTG 1 -- int10--------
    rs1494055691,2
    --72785794(+) TCAAAC/GTCAGT 1 -- int10--------
    rs1905363811,2
    --72786501(+) GTTTTC/GTCTTT 1 -- int10--------
    rs1447660301,2
    --72786513(+) CCCCTA/CTCTGA 1 -- int10--------
    rs1810489941,2
    C--72786703(+) ACAGGA/CCTTCA 1 -- int10--------
    rs1860398261,2
    --72786729(+) ACAGAA/GAATAG 1 -- int10--------

    HapMap Linkage Disequilibrium report for CHIC1 (72782984 - 72906937 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for CHIC1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2490652CNV Deletion19546169
    nsv515213CNV Loss21397061
    nsv6958CNV Loss18451855
    nsv499728CNV Loss21111241
    esv23979CNV Loss19812545

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing CHIC1
    DNA2.0 Custom Variant and Variant Library Synthesis for CHIC1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for CHIC1:    About MalaCards
    leukemia    


    CHIC1 for disorders           About GeneDecksing


    Export disorders for CHIC1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CHIC1 gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with CHIC1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Localization and expression analysis of a novel conserved brain expressed transcript, Brx/BRX, lying within the Xic/XIC candidate region. (PubMed id 9321471)1, 2, 3 Simmler M.-C....Avner P. (1997)
    2. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. A new family of small, palmitoylated, membrane-associated proteins, characterized by the presence of a cysteine-rich hydrophobic motif. (PubMed id 11257495)1, 3 Cools J.... Marynen P. (2001)
    5. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    6. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    7. Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)
    8. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    9. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    10. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 53344 HGNC: 1934 AceView: CHIC1 Ensembl:ENSG00000204116 euGenes: HUgn53344
    ECgene: CHIC1 H-InvDB: CHIC1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CHIC1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CHIC1 gene:
    Search GeneIP for patents involving CHIC1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
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     Regulatory tfbs in CHIC1 promoter
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     Browse Sino Biological Proteins and Antibodies
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     Proteins for CHIC1
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     inGenious Targeting Laboratory - Custom generated mouse model solutions for CHIC1
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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