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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CHGB Gene

protein-coding   GIFtS: 56
GCID: GC20P005891

chromogranin B (secretogranin 1)


(Previous symbol: SCG1)
 Explore 41 diseases affiliated with
CHGB via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for CHGB    

Aliases
for CHGB gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Chromogranin B (Secretogranin 1)1 2     Secretogranin-11
SCG11 2 3 5     SgI3
Secretogranin I2 3     CgB3
CgB3     Chromogranin-B3
Chromogranin-B3     SgI3
Secretogranin B2     

External Ids:    HGNC: 19301   Entrez Gene: 11142   Ensembl: ENSG000000891997   OMIM: 1189205   UniProtKB: P050603   

Export aliases for CHGB gene to outside databases

Previous GC identifers: GC20P005880 GC20P005840 GC20P005887 GC20P005848


Summaries
for CHGB gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for CHGB:
This gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. This
protein may serve as a precursor for regulatory peptides. (provided by RefSeq, Jan 2009)

UniProtKB/Swiss-Prot: SCG1_HUMAN, P05060
Function: Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other
biologically active peptides

Gene Wiki entry for CHGB (Secretoneurin)


Genomic Views
for CHGB gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NC_018931.1  NT_011387.8  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CHGB gene promoter:
         AP-1   AP-2alpha isoform 3   AML1a   NRSF form 1   AP-2alpha isoform 2   NRSF form 2   AP-2alpha isoform 4   AP-2alpha   RSRFC4   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CHGB promoter sequence
   Search SABiosciences Chromatin IP Primers for CHGB

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHGB


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20pter-p12   Ensembl cytogenetic band:  20p12.3   HGNC cytogenetic band: 20pter-p12

CHGB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CHGB gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P005891:  view genomic region     (about GC identifiers)

Start:
 5,891,974 bp from pter      End:
 5,906,007 bp from pter
Size:
 14,034 bases      Orientation:
 plus strand

Proteins
for CHGB gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: SCG1_HUMAN, P05060 (See protein sequence)
Recommended Name: Secretogranin-1 precursor  
Size: 677 amino acids; 78276 Da
Subcellular location: Secreted. Note=Neuroendocrine and endocrine secretory granules
Sequence caution: Sequence=BAD92949.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A8K021 Q59EU9 Q6IBS6 Q9BQV6 Q9UC25 Q9UJA6

Explore the universe of human proteins at neXtProt for CHGB: NX_P05060

Post-translational modifications:

  • Extensively processed by limited proteolysis at conserved basic residues. Alternative processing are seen in different
    • tissues (By similarity)1
  • O-glycosylated1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P05060

    • CHGB Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001810.2  
    ENSEMBL proteins: 
     ENSP00000368244   ENSP00000416643  

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    Novus Biologicals CHGB Protein
    Novus Biologicals CHGB Lysate
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    ProSpec Recombinant Protein for CHGB
    Uscn Proteins for CHGB

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0030141secretory granule IEA--


    CHGB for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for CHGB

    Protein Domains /
    Families
    for CHGB gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    CHGB for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR001819 Chromogranin_AB
     IPR018054 Chromogranin_CS
     IPR001990 Granin

    Graphical View of Domain Structure for InterPro Entry P05060

    ProtoNet protein and cluster: P05060

    1 Blocks protein family: IPB001990 Chromogranin/secretogranin

    UniProtKB/Swiss-Prot: SCG1_HUMAN, P05060
    Similarity: Belongs to the chromogranin/secretogranin protein family


    Function
    for CHGB gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: SCG1_HUMAN, P05060
    Function: Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other
    biologically active peptides

         Genatlas biochemistry entry for CHGB:
    chromogranin B (catecholamine and norepenephrine secretory protein)

    miRNA
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    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CHGB (see all 7)
    OriGene shRNA RFP: CHGB
    OriGene siRNA: CHGB
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CHGB

    Gene Editing
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    Clone
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    Search LifeMap BioReagents cell lines for CHGB

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHGB

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005179hormone activity TAS3608978
    GO:0005515protein binding IPI--


    CHGB for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-outs for CHGB: Chgbtm1Wbh Chgbtm1Ribo
         3 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Chgb):
     endocrine/exocrine gland  homeostasis/metabolism  nervous system 

    CHGB for phenotypes           About GeneDecksing


    Pathways & Interactions
    for CHGB gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CHGB

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    5/48 Interacting proteins for CHGB (P050601, 2, 3 ENSP000003682444) via UniProtKB, MINT, STRING, and/or I2D (see all 48)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PTENP604842, 3, ENSP000003610214MINT-63918 I2D: score=5 STRING: ENSP00000361021
    RAC2P151532, 3, ENSP000002490714MINT-8267918 I2D: score=2 STRING: ENSP00000249071
    ATXN2Q997002, 3MINT-65287 I2D: score=5 
    CBFBQ139512, 3MINT-65560 I2D: score=5 
    CCDC92Q53HC02, 3MINT-65500 I2D: score=5 
    About this table

    Drugs & Compounds
    for CHGB gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    CHGB for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CHGB
    10/17 Novoseek chemical compound relationships for CHGB gene (see all 17)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    secretoneurin 92.1 20 11931350 (3), 9891437 (2), 14724070 (2), 18448176 (2) (see all 12)
    peptidylglycine 57.3 1 7865135 (1)
    inositol 1,4,5 trisphosphate 42.6 7 12438140 (1), 17395556 (1), 18020452 (1), 18420944 (1) (see all 5)
    catecholamine 36.3 8 20359597 (2), 15138309 (1), 18180394 (1), 14637105 (1)
    dithiothreitol 26.8 15 8491204 (4), 7834494 (3), 10409115 (2), 8082769 (2)
    oligonucleotide 13.9 2 7551295 (1)
    calcium 8.98 22 8663344 (4), 18020452 (1), 18420944 (1), 17997581 (1) (see all 10)
    norepinephrine 0.612 1 8978502 (1)
    sucrose 0 1 9535898 (1)
    threonine 0 2 1601888 (1)

    Search CenterWatch for drugs/clinical trials and news about CHGB / SCG1 

    Transcripts
    for CHGB gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for CHGB gene: 
    NM_001819.2  

    Unigene Cluster for CHGB:

    Chromogranin B (secretogranin 1)
    Hs.516874  [show with all ESTs]
    Unigene Representative Sequence: NM_001819
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000378961(uc002wmg.3 uc010zqz.2) ENST00000455042 ENST00000488832


    miRNA
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    Inhib. RNA
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    Primer
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHGB

    Additional cDNA sequence: 

    AB209712.1 AK054871.1 AK225125.1 AK289386.1 AK293536.1 AK312237.1 BC000375.2 CR456726.1 
    Y00064.1 

    13 DOTS entries:

    DT.117082  DT.100877878  DT.100877870  DT.100877876  DT.95077028  DT.95288716  DT.100877885  DT.100877887 
    DT.120811216  DT.91945588  DT.95070611  DT.92445291  DT.95070612 

    24/377 AceView cDNA sequences (see all 377):

    BM505584 BU789210 BM857542 BQ417412 AA319410 BU788954 BQ614332 CA776205 
    BM930895 BM314781 CD251136 BQ722551 AA318905 BM505464 BU073302 AA318741 
    CB069983 BM310460 BG656520 BQ719565 CD106843 BU951898 CA949929 CB068720 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for CHGB (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b
    SP1:                                -     -                                                         
    SP2:                                      -                 -                                       
    SP3:                                -     -                 -                                       
    SP4:                                                        -                                       
    SP5:                          -     -     -     -           -                                       


    ECgene alternative splicing isoforms for CHGB

    Expression
    for CHGB gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CHGB expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CTTATGACAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    CHGB expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    7 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Gut TubeMidgutMidgut Endoderm CellsEndoderm
    Neural TubeNeural TubeSpinal Neural Tube CellsNeural Ectoderm
    Skeletal MuscleHyoid Arch MusclesMuscle Progenitor CellsSkeletal Muscle
    Skeletal MuscleMandibular Arch MusclesMuscle Progenitor CellsSkeletal Muscle
    EyeRetinaEye
    Gut TubeMidgutGut Tube
    Spinal CordPresumptive Spinal CordSpinal Cord
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See CHGB Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CHGB

    SOURCE GeneReport for Unigene cluster: Hs.516874

    UniProtKB/Swiss-Prot: SCG1_HUMAN, P05060
    Tissue specificity: Expressed in the adrenal medulla, and in pheochromocytoma. Not expressed in liver

        SABiosciences Expression via Pathway-Focused PCR Array including CHGB: 
              Parkinson's Disease in human mouse rat

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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHGB

    Orthologs
    for CHGB gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for CHGB gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Chgb1 , 5 chromogranin B1, 5 76.33(n)1
    65.86(a)1    		   2 (64.74 cM)5
    126531  NM_007694.41  NP_031720.11 
     1327812785 
    chicken
    (Gallus gallus)    		 Aves CHGB1 chromogranin B (secretogranin 1) 53.73(n)
    39.12(a)    		   421312  XM_419377.3  XP_419377.1 
    lizard
    (Anolis carolinensis)    		 Reptilia CHGB6
    		 --
    		 29(a)
    		 1 ↔ 1
    		 AAWZ02036810(5060-19492)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia Str.190442 Transcribed sequence with weak similarity to protein more 71.47(n)    BX773071.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii chgb6
    		 chromogranin B
    		 15(a)
    		 1 ↔ 1
    		 20(45944157-45954607)


    ENSEMBL Gene Tree for CHGB (if available)
    TreeFam Gene Tree for CHGB (if available) 

    Paralogs
    for CHGB gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CHGB gene
    CHGA2  

    CHGB for paralogs           About GeneDecksing



    Genomic Variants
    for CHGB gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/362 NCBI SNPs in CHGB are shown (see all 362)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 20 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs568479611,2
    		C,F,--5890001(+) TCAGCG/ACATCT 1 -- us2k11Minor allele frequency- A:0.16WA 118
    rs1408166301,2
    		--5890063(+) TGCAGA/TTCTGC 1 -- us2k10--------
    rs2361361,2
    		C,F,O,A,H,--5890071(+) TGCAGC/TCAAAG 1 -- us2k1 tfbs312Minor allele frequency- T:0.45NA WA CSA EA 686
    rs1156995921,2
    		F,--5890134(+) TTTAAA/GCAGAC 1 -- us2k11Minor allele frequency- G:0.06WA 118
    rs2361371,2
    		C,F,A,H,--5890145(+) TCTTTC/TGTGCC 1 -- us2k122Minor allele frequency- T:0.42NS EA NA WA CSA 2399
    rs730831881,2
    		C,F,--5890247(+) TTCCCT/CGAATG 1 -- us2k12Minor allele frequency- C:0.03WA NA 238
    rs1152337661,2
    		F,--5890329(+) AGGAAG/ATTGTA 1 -- us2k11Minor allele frequency- A:0.02WA 118
    rs2361381,2
    		C,F,H,--5890360(+) CTAGTT/CACTTC 1 -- us2k116Minor allele frequency- C:0.15NS EA NA WA CSA 768
    rs1853439551,2
    		--5890410(+) ATCACA/GGTACA 1 -- us2k10--------
    rs61398681,2
    		C,A,--5890457(+) CTTTTC/TTTTCT 1 -- us2k1 trp34Minor allele frequency- T:0.12NA WA CSA 8

    HapMap Linkage Disequilibrium report for CHGB (5891974 - 5906007 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for CHGB: --
    Human Gene Mutation Database (HGMD): CHGB

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHGB
    DNA2.0 Custom Variant and Variant Library Synthesis for CHGB

    Disorders / Diseases
    for CHGB gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    CHGB for disorders           About GeneDecksing

    OMIM gene information: 118920    OMIM disorders: --

    20/41 diseases for CHGB (see all 41):    About MalaCards
    multiple endocrine neoplasia    temporal lobe epilepsy    parathyroid adenoma    primitive neuroectodermal tumor
    glucagonoma    amyotrophic lateral sclerosis    pituitary adenoma    neuroectodermal tumors
    frontotemporal dementia    lateral sclerosis    neuroendocrine tumor    female breast carcinoma
    prolactinoma    pancreatic endocrine tumors    paraganglioma    pituitary tumor
    adenoma    neuronitis    carcinoid tumors    adrenocortical tumor

    10/25 Novoseek disease relationships for CHGB gene (see all 25)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    carcinoid 63.9 19 7891024 (2), 9891437 (2), 7599788 (2), 1856109 (1) (see all 9)
    neuroendocrine tumors 60.5 6 1928556 (1), 7551295 (1), 10697270 (1)
    pheochromocytoma 55.9 15 1882087 (3), 15601318 (3), 9037129 (2), 1437706 (1) (see all 8)
    pituitary adenoma 48.6 6 1552186 (2), 8396420 (2), 8669489 (1), 1928557 (1)
    prolactinoma 45.7 3 1342950 (1), 2294779 (1)
    multiple endocrine neoplasia 45.3 2 7891024 (1), 17639059 (1)
    glucagonoma 43.9 6 1954895 (4), 7952497 (1)
    thyroid carcinoma medullary 39.1 3 9664908 (1), 19215381 (1)
    adenoma 35 17 8396420 (3), 14586070 (2), 7680355 (2), 8669489 (2) (see all 7)
    parathyroid adenoma 33.9 3 1342950 (1), 2294779 (1)

    Genetic Association Database (GAD): CHGB
    Human Genome Epidemiology (HuGE) Navigator: CHGB (11 documents)

    Export disorders for CHGB gene to outside databases

    Publications
    for CHGB gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CHGB gene, integrated from 9 sources (see all 208):
    (articles sorted by number of sources associating them with CHGB)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The primary structure of human secretogranin I (chromogranin B): comparison with chromogranin A reveals homologous terminal domains and a large intervening variable region. (PubMed id 3608978)1, 2, 3 Benedum U.M.... Huttner W.B. (1987)
    2. Chromogranin B: isolation from pheochromocytoma, N-terminal sequence, tissue distribution and secretory vesicle processing. (PubMed id 1882087)1, 2, 9 Gill B.M.... O'Connor D.T. (1991)
    3. Association between chromogranin b gene polymorphisms and schizophrenia in the Japanese population. (PubMed id 15219467)1, 4, 9 Iijima Y....Arinami T. (2004)
    4. Identification and characterization of phosphorylated proteins in the human pituitary. (PubMed id 14997482)1, 2, 9 Giorgianni F.... Desiderio D.M. (2004)
    5. Polymorphisms of chromogranin B gene associated with schizophrenia in Chinese Han population. (PubMed id 11959426)1, 4, 9 Zhang B....He L. (2002)
    6. Phosphoproteomic analysis of the human pituitary. (PubMed id 16807684)1, 2 Beranova-Giorgianni S.... Giorgianni F. (2006)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    9. Chromogranin B (secretogranin I), a putative precursor of two novel pituitary peptides through processing at paired basic residues. (PubMed id 3678488)1, 2 Benjannet S.... Chretien M. (1987)
    10. GAWK, a novel human pituitary polypeptide: isolation, immunocytochemical localization and complete amino acid sequence. (PubMed id 3970711)1, 2 Benjannet S....Chretien M. (1985)

    External Searches for CHGB gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing CHGB gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 1114 HGNC: 1930 AceView: CHGB Ensembl:ENSG00000089199 euGenes: HUgn1114
    ECgene: CHGB H-InvDB: CHGB

    Other Databases showing CHGB gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing CHGB gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CHGB Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for CHGB gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for CHGB gene:
    Search GeneIP for patents involving CHGB

    GeneCards and IP:
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