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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CHD5 Gene

protein-coding   GIFtS: 55
GCID: GC01M006096

chromodomain helicase DNA binding protein 5
 Explore 9 diseases affiliated with
CHD5 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for CHD5    

Aliases
for CHD5 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Chromodomain Helicase DNA Binding Protein 51 2     EC 3.6.4.123
CHD-52 3     KIAA04443
ATP-Dependent Helicase CHD52 3     EC 3.6.18
Chromodomain-Helicase-DNA-Binding Protein 52     

External Ids:    HGNC: 168161   Entrez Gene: 260382   Ensembl: ENSG000001162547   OMIM: 6107715   UniProtKB: Q8TDI03   

Export aliases for CHD5 gene to outside databases

Previous GC identifers: GC01M005970 GC01M005758 GC01M005871 GC03U900582 GC01M005310


Summaries
for CHD5 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for CHD5:
This gene encodes a member of the chromodomain helicase DNA-binding protein family. Members of this family are
characterized by a chromodomain, a helicase ATP-binding domain and an additional functional domain. This gene encodes
a neuron-specific protein that may function in chromatin remodeling and gene transcription. This gene is a potential
tumor suppressor gene that may play a role in the development of neuroblastoma. (provided by RefSeq, Feb 2012)

UniProtKB/Swiss-Prot: CHD5_HUMAN, Q8TDI0
Function: May play a role in the development of the nervous system and the pathogenesis of neural tumors

Gene Wiki entry for CHD5


Genomic Views
for CHD5 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_021937.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CHD5 gene promoter:
         GATA-3   Nkx2-2   Egr-1   Brachyury   NRSF form 1   NRSF form 2   Egr-4   FOXL1   AREB6   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CHD5 promoter sequence
   Search SABiosciences Chromatin IP Primers for CHD5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHD5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.31   Ensembl cytogenetic band:  1p36.31   HGNC cytogenetic band: 1p36.3

CHD5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CHD5 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M006096:  view genomic region     (about GC identifiers)

Start:
 6,161,847 bp from pter      End:
 6,240,194 bp from pter
Size:
 78,348 bases      Orientation:
 minus strand

Proteins
for CHD5 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CHD5_HUMAN, Q8TDI0 (See protein sequence)
Recommended Name: Chromodomain-helicase-DNA-binding protein 5  
Size: 1954 amino acids; 223050 Da
Subcellular location: Nucleus (By similarity)
Secondary accessions: O75032 Q5TG89 Q7LGH2 Q9UFR9

Explore the universe of human proteins at neXtProt for CHD5: NX_Q8TDI0

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8TDI0

    • 4/22 DME Specific Peptides for CHD5 (Q8TDI0) (see all 22)
     DEAHRLK  TGTPLQN  NQSKFFR  FLLSTRA 

    CHD5 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_056372.1  
    ENSEMBL proteins: 
     ENSP00000367245   ENSP00000262450   ENSP00000466440   ENSP00000466706   ENSP00000367238  
     ENSP00000433676   ENSP00000468624   ENSP00000367260  

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    Uscn Proteins for CHD5

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--


    CHD5 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for CHD5 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    CHD5 for domains           About GeneDecksing

    5/17 InterPro domains/families (see all 17):
     IPR009463 DUF1087
     IPR001841 Znf_RING
     IPR001965 Znf_PHD
     IPR000953 Chromo_domain/shadow
     IPR000330 SNF2_N

    Graphical View of Domain Structure for InterPro Entry Q8TDI0

    ProtoNet protein and cluster: Q8TDI0

    5/7 Blocks protein families (see all 7):
    IPB000330 SNF2 related domain
    IPB000953 Chromo domain
    IPB001841 Zn-finger
    IPB001965 Zn-finger-like
    IPB002464 ATP-dependent helicase


    UniProtKB/Swiss-Prot: CHD5_HUMAN, Q8TDI0
    Similarity: Belongs to the SNF2/RAD54 helicase family
    Similarity: Contains 2 chromo domains
    Similarity: Contains 1 helicase ATP-binding domain
    Similarity: Contains 1 helicase C-terminal domain
    Similarity: Contains 2 PHD-type zinc fingers


    Function
    for CHD5 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: CHD5_HUMAN, Q8TDI0
    Function: May play a role in the development of the nervous system and the pathogenesis of neural tumors
    Catalytic activity: ATP + H(2)O = ADP + phosphate

    Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.121

    miRNA
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    hsa-miR-548j hsa-miR-3607-3p hsa-miR-15a hsa-miR-106a hsa-miR-219-5p hsa-miR-30d hsa-miR-519a hsa-miR-30a
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    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0004386helicase activity ----
    GO:0005524ATP binding IEA--
    GO:0008026ATP-dependent helicase activity IEA--
    GO:0008270zinc ion binding IEA--


    CHD5 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for CHD5:
     Decreased Wnt reporter activit 


    Pathways & Interactions
    for CHD5 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CHD5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/17 Interacting proteins for CHD5 (Q8TDI03 ENSP000002624504) via UniProtKB, MINT, STRING, and/or I2D (see all 17)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    RBBP4Q090283, ENSP000003625924I2D: score=1 STRING: ENSP00000362592
    DVL2O146413I2D: score=4 
    SSU72Q9NP773I2D: score=4 
    EZH2Q159103I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0016568chromatin modification IEA--


    CHD5 for ontologies           About GeneDecksing



    Drugs & Compounds
    for CHD5 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CHD5
    Search CenterWatch for drugs/clinical trials and news about CHD5 

    Transcripts
    for CHD5 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for CHD5 gene: 
    NM_015557.2  

    Unigene Cluster for CHD5:

    Chromodomain helicase DNA binding protein 5
    Hs.522898  [show with all ESTs]
    Unigene Representative Sequence: NM_015557
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000378006 ENST00000262450(uc001amb.2) ENST00000475121 ENST00000462991
    ENST00000377999 ENST00000496404 ENST00000491020 ENST00000378021(uc001alz.2 uc001ama.2 uc001amc.1)


    miRNA
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    8/81 QIAGEN miScript miRNA Assays for microRNAs that regulate CHD5 (see all 81):
    hsa-miR-548j hsa-miR-3607-3p hsa-miR-15a hsa-miR-106a hsa-miR-219-5p hsa-miR-30d hsa-miR-519a hsa-miR-30a
    SwitchGear 3'UTR luciferase reporter plasmid: CHD5 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CHD5 (see all 4)
    OriGene shRNA RFP: CHD5
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    Clone
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHD5

    Additional cDNA sequence: 

    AB007913.1 AF425231.1 AK091386.1 AK126012.1 AL117491.1 AL137693.1 BC048142.1 

    8 DOTS entries:

    DT.121366469  DT.100748795  DT.448559  DT.101980704  DT.100677293  DT.40306474  DT.100748794  DT.99931944 

    24/1193 AceView cDNA sequences (see all 1193):

    AW205724 N48023 BM766499 AL559775 BG421223 CR617440 AW952427 BU069971 
    BQ650409 BE780006 AA075111 BM710282 AI280189 CB160174 T32038 AA310356 
    AA736989 AI337839 AA055008 BU686960 T31408 BF114898 BF795028 BE254367 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for CHD5    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19a · 19b ^ 20a · 20b ^ 21 ^ 22 ^
    SP1:                                                              -                                                                             -               
    SP2:                                                              -                                                                             -               
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 23 ^ 24 ^ 25a · 25b ^ 26 ^ 27 ^ 28a · 28b ^ 29 ^ 30 ^ 31 ^ 32a · 32b ^ 33 ^ 34 ^ 35 ^ 36 ^ 37 ^ 38 ^ 39 ^ 40 ^ 41a · 41b
    SP1:        -                                                                                                                                 
    SP2:        -                                   -                                                                                             
    SP3:        -                                                                                                           -                     
    SP4:                                                                                                                                          
    SP5:                                                                                                                                          


    ECgene alternative splicing isoforms for CHD5

    Expression
    for CHD5 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CHD5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGAGCCAGAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    CHD5 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    7 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Spinal CordSpinal Dorsal ColumnsDorsal Spinal Cord Progenitor CellsSpinal Cord
    Spinal CordSpinal Ventral ColumnsVentral Spinal Cord Progenitor CellsMotor Neurons
    BrainMedulla OblongataBrain
    Neural TubeMetencephalonNeural Tube
    Neural TubeTelencephalonNeural Tube
    Spinal CordSpinal Dorsal ColumnsSpinal Cord
    Spinal CordSpinal Ventral ColumnsSpinal Cord
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See CHD5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CHD5

    SOURCE GeneReport for Unigene cluster: Hs.522898

    UniProtKB/Swiss-Prot: CHD5_HUMAN, Q8TDI0
    Tissue specificity: Preferentially expressed in total brain, fetal brain, and cerebellum. It is also moderately
    expressed in the adrenal gland

        SABiosciences Expression via Pathway-Focused PCR Array including CHD5: 
              Epigenetic Chromatin Remodeling Factors in human mouse rat

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    In Situ
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    Orthologs
    for CHD5 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CHD5 gene from 7/25 species (see all 25)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves CHD51 chromodomain helicase DNA binding protein 5 81.43(n)
    89.24(a)    		   100857108  XM_003642519.1  XP_003642567.1 
    lizard
    (Anolis carolinensis)    		 Reptilia CHD56
    		 --
    		 83(a)
    		 1 ↔ 1
    		 GL343833.1(8538-32186)
    zebrafish
    (Danio rerio)    		 Actinopterygii chd51 chromodomain helicase DNA binding protein 5 72.19(n)
    79.22(a)    		   553422  XM_003199497.1  XP_003199545.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Chd36
    Mi-26
    		 --
    		 57(a)
    51(a)
    		 possible ortholog
    1 ↔ many
    		 3L(19440273-19443338)
    3L(19875151-19903315)
    worm
    (Caenorhabditis elegans)    		 Secernentea chd-36
    let-4186
    		 LEThal family member (let-418)
    		 49(a)
    48(a)
    		 possible ortholog
    possible ortholog
    		 X(12846360-12852531)
    V(5826816-5832844)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons PKL1 CHD3-type chromatin-remodeling factor PICKLE 52.17(n)
    47.01(a)    		   817055  NM_128074.3  NP_565587.1 
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    		 CHD3-type chromatin-remodeling factor PICKLE, puta...
    CHD3-type chromatin-remodeling factor PICKLE, puta...
    		 35(a)
    26(a)
    		 1 ↔ many
    possible ortholog
    		 6(4166230-4182941)
    1(38227769-38236185)


    ENSEMBL Gene Tree for CHD5 (if available)
    TreeFam Gene Tree for CHD5 (if available) 

    Paralogs
    for CHD5 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CHD5 gene
    CHD62  CHD92  CHD42  CHD12  CHD72  CHD82  CHD32  CHD22  
    18 SIMAP similar genes for CHD5 using alignment to 7 protein entries:     CHD5_HUMAN (see all proteins):
    DKFZp434K213    DKFZp434P202    SMARCA4    CHD2    CHD3    CHD4
    ZNF212    AIRE    NF2    CHD8    SHPRH    SP110
    CHD9    SMARCA5    CHD1L    HELLS    SMARCA1    DNMT1

    CHD5 for paralogs           About GeneDecksing



    Genomic Variants
    for CHD5 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1749 NCBI SNPs in CHD5 are shown (see all 1749)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 1 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs784613381,2
    		--6161839(+) AAAAAG/ACCTCT 1 -- ds50011Minor allele frequency- A:0.50CSA 2
    rs10642871,2
    		C--6161939(-) GGACAG/AAGGCT 1 -- ut313Minor allele frequency- A:0.00MN NA 188
    rs127583411,2
    		C,--6161959(+) TGGGCG/AAAGAC 1 -- ut31 ese33Minor allele frequency- A:0.26NA EA 242
    rs1903579071,2
    		--6161969(+) CCAGAC/TAAGCC 1 -- ut310--------
    rs66964891,2
    		C,H,--6162054(+) GCGCCC/TTGCAC 1 -- ut3110Minor allele frequency- T:0.23NA WA CSA EA 373
    rs782407701,2
    		--6162110(+) AAAGGG/AGTCGG 1 -- ut312Minor allele frequency- A:0.02CSA WA 120
    rs10642851,2
    		C,F,H--6162174(-) GGGGTC/TTGAGT 1 -- ut31 ese34Minor allele frequency- T:0.09NS NA 672
    rs1386826561,2
    		C,--6162229(+) CTCCAA/GTCGCT 1 -- ut310--------
    rs1834099011,2
    		--6162270(+) CCAACA/GGGCCC 1 -- ut310--------
    rs1471289321,2
    		--6162332(+) TAAAG-/AAAAAA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for CHD5 (6161847 - 6240194 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 4 variations for CHD5
         4 CNVs: 29827 4200 9869 70527

    SABiosciences Cancer Mutation PCR Assays
    1 SABiosciences qBiomarker Copy Number PCR Array containing CHD5:
    Glioma
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHD5
    DNA2.0 Custom Variant and Variant Library Synthesis for CHD5

    Disorders / Diseases
    for CHD5 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    CHD5 for disorders           About GeneDecksing

    OMIM gene information: 610771    OMIM disorders: --

    9 diseases for CHD5:    About MalaCards
    neuroblastoma    laryngeal squamous cell carcinoma    squamous cell carcinoma    neuronitis
    laryngitis    ovarian cancer    gastric cancer    carcinoma
    melanoma

    Human Genome Epidemiology (HuGE) Navigator: CHD5 (4 documents)

    Export disorders for CHD5 gene to outside databases

    Publications
    for CHD5 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CHD5 gene, integrated from 9 sources (see all 29):
    (articles sorted by number of sources associating them with CHD5)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. CHD5, a new member of the chromodomain gene family, is preferentially expressed in the nervous system. (PubMed id 12592387)1, 2, 3 Thompson P.M....Brodeur G.M. (2003)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    3. Characterization of cDNA clones in size-fractionated cDNA libraries from human brain. (PubMed id 9455484)1, 2 Seki N.... Ohara O. (1997)
    4. CHD5, a tumor suppressor gene deleted from 1p36.31 in neuroblastomas. (PubMed id 18577749)1, 9 Fujita T....Brodeur G.M. (2008)
    5. Chromatin remodeling factor CHD5 is silenced by promoter CpG island hypermethylation in human cancer. (PubMed id 18698156)1, 9 Mulero-Navarro S. and Esteller M. (2008)
    6. CHD5 is down-regulated through promoter hypermethylat ion in gastric cancer. (PubMed id 19840376)1, 9 Wang X....Lam Y.W. (2009)
    7. The quest for the 1p36 tumor suppressor. (PubMed id 18413720)1, 9 Bagchi A. and Mills A.A. (2008)
    8. Mechanisms of CHD5 Inactivation in neuroblastomas. (PubMed id 22294723)1 Koyama H....Brodeur G.M. (2012)
    9. Analysis of common variations in tumor-suppressor gene s on chr1p36 among Caucasian women with endometriosis. (PubMed id 22910690)1 Falconer H....D'Hooghe T.M. (2012)
    10. A three-gene expression signature model for risk strat ification of patients with neuroblastoma. (PubMed id 22328561)1 Garcia I....Lavarino C. (2012)

    External Searches for CHD5 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    Genome Databases showing CHD5 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26038 HGNC: 16816 AceView: RPL22andCHD5 Ensembl:ENSG00000116254 euGenes: HUgn26038
    ECgene: CHD5 H-InvDB: CHD5

    Other Databases showing CHD5 gene

    (According to HUGE)
    About This Section
    HUGE: KIAA0444

    Specialized Databases showing CHD5 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CHD5 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for CHD5 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for CHD5 gene:
    Search GeneIP for patents involving CHD5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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