CHD3 Gene
protein-coding GIFtS: 60
GCID: GC17P007788
|
|
chromodomain helicase DNA binding protein 3
| |
Aliases
for CHD3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromodomain Helicase DNA Binding Protein 31 2 | | ATP-Dependent Helicase CHD32 3 | | Mi-2a1 2 | | HZFH1 | | Mi2-ALPHA1 2 | | Chromodomain-Helicase-DNA-Binding Protein 32 | | ZFH1 2 | | Zinc-Finger Helicase (Snf2-Like)2 | | Mi-2 Autoantigen 240 KDa Protein2 3 | | EC 3.6.4.123 | | Zinc Finger Helicase2 3 | | Mi2-Alpha1 | | CHD-32 3 | | EC 3.6.18 |
Export aliases for CHD3 gene to outside databasesPrevious GC identifers: GC17P008257 GC17P008659 GC17P007730 GC17P007988 GC17P007992 GC17P007732 GC17U900584 |
Summaries
for CHD3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CHD3:
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatinorganization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of ahistone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin bydeacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodiesagainst this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcriptsencoding different isoforms have been described. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: CHD3_HUMAN, Q12873Function: Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin bydeacetylating histones. Required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindleorganization and centrosome integrity
Gene Wiki entry for CHD3
|
Genomic Views
for CHD3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010718.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CHD3 gene promoter:
Egr-3 PPAR-alpha AREB6 Pax-5 HFH-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for CHD3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHD3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17p13.1 Ensembl cytogenetic band: 17p13.1 HGNC cytogenetic band: 17p13CHD3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P007788: view genomic region
(about GC identifiers)
Start:
|
7,788,123 bp from pter |
End:
|
7,816,078 bp from pter |
Size:
|
27,956 bases |
Orientation:
|
plus strand |
|
Proteins
for CHD3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CHD3_HUMAN, Q12873 (See
protein sequence)Recommended Name: Chromodomain-helicase-DNA-binding protein 3 Size: 2000 amino acids; 226592 Da
Subunit: Central component of the nucleosome remodeling and histone deacetylase (NuRD) repressive complex. Interactswith TRIM28 and SERBP1. Interacts (via its C-terminal) with HABP4. Interacts with PCNT; the interaction regulatescentrosome integrity
Subcellular location: Nucleus. Cytoplasm, cytoskeleton, centrosome. Note=Associates with centrosomes in interphase andmitosis
Miscellaneous: One of the main antigens reacting with anti-MI-2 positive sera of dermatomyositis
Sequence caution: Sequence=AAB87383.1; Type=Miscellaneous discrepancy; Note=Differs from position 1967 onward forunknown reasons;
Secondary accessions: D3DTQ9 Q9Y4I0Alternative splicing: 2 isoforms: Q12873-1 Q12873-2 Explore the universe of human proteins at neXtProt for CHD3: NX_Q12873
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q12873
4/23 DME Specific Peptides for CHD3 (Q12873) (see all 23)
CHD3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001005271.2 NP_001005273.1 NP_005843.2
ENSEMBL proteins: ENSP00000369716 ENSP00000350907 ENSP00000332628 ENSP00000405861 ENSP00000458861 ENSP00000467547 ENSP00000395252 ENSP00000459321 ENSP00000411959
Human Recombinant Protein Products:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
CHD3 for ontologies About GeneDecksing
CHD3 Antibody Products:
Assay Products for CHD3: |
Protein
Domains /
Families
for CHD3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CHD3 for domains About GeneDecksing
5/19 InterPro domains/families (see all 19):Graphical View of Domain Structure for InterPro Entry Q12873ProtoNet protein and cluster: Q12873 5/7 Blocks protein families (see all 7): IPB000330 SNF2 related domain IPB000953 Chromo domain IPB001841 Zn-finger IPB001965 Zn-finger-like IPB002464 ATP-dependent helicase
UniProtKB/Swiss-Prot: CHD3_HUMAN, Q12873Similarity: Belongs to the SNF2/RAD54 helicase familySimilarity: Contains 2 chromo domainsSimilarity: Contains 1 helicase ATP-binding domainSimilarity: Contains 1 helicase C-terminal domainSimilarity: Contains 2 PHD-type zinc fingers |
Function
for CHD3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CHD3_HUMAN, Q12873Function: Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin bydeacetylating histones. Required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindleorganization and centrosome integrityCatalytic activity: ATP + H(2)O = ADP + phosphate Genatlas biochemistry entry for CHD3:DNA binding protein with two chromatin organization (chromo) domains,and a helicase domain,3,component of the chromatinremodeling complex
Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.121
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHD3 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHD3 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): CHD3 (NM_005852) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CHD3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHD3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHD3 |
Gene Ontology (GO): 5/8 molecular function terms (GO ID links to tree view) (see all 8): About this table
CHD3 for ontologies About GeneDecksing
|
Pathways & Interactions
for CHD3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Transcription_Sin3 and NuRD in transcription regulation | | | 2 | Signaling events mediated by HDAC Class I | | | 3 | Chromatin Regulation / Acetylation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for CHD3
1 
Cell Signaling Technology (CST) Pathway for CHD3
1  GeneGo (Thomson Reuters) Pathway for CHD3
1  BioSystems Pathway for CHD3
CHD3 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CHD3
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/733 Interacting proteins for CHD3 (Q128731, 2, 3 ENSP000003697164) via UniProtKB, MINT, STRING, and/or I2D (see all 733)About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table
CHD3 for ontologies About GeneDecksing
|
Drugs & Compounds
for CHD3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CHD3
Search CenterWatch for drugs/clinical trials and news about CHD3
|
Transcripts
for CHD3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CHD3 gene (3 alternative transcripts): NM_001005271.2 NM_001005273.2 NM_005852.3 Unigene Cluster for CHD3: Chromodomain helicase DNA binding protein 3 Hs.25601 [show with all ESTs]Unigene Representative Sequence: NM_00100527117 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000380358(uc002gjd.2) ENST00000358181(uc002gjf.2 uc002gjg.1)
ENST00000330494(uc002gje.2) ENST00000570758 ENST00000574022 ENST00000452447
ENST00000572579 ENST00000571249 ENST00000479080 ENST00000470531(uc002gjh.2)
ENST00000466233 ENST00000473376 ENST00000572750 ENST00000439235 ENST00000573936
ENST00000449744 ENST00000481999(uc002gjj.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHD3 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHD3 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): CHD3 (NM_005852) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CHD3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHD3 |
Additional cDNA sequence: AF064844.1 AK096555.1 AK125928.1 AK296725.1 AK296937.1 AK308362.1 BC110648.1 U08379.1 U91543.1 24 DOTS entries: DT.101955781 DT.91789628 DT.95236710 DT.445459 DT.91907399 DT.92447872 DT.120935860 DT.101957495 DT.92447865 DT.86850991 DT.92447876 DT.92447869 DT.100666962 DT.92447864 DT.100790238 DT.120935990 DT.121289811 DT.100678541 DT.100821703 DT.92447861 DT.92476134 DT.95226693 DT.97769182 DT.120935877
GeneLoc Exon Structure
5/27 Alternative Splicing Database (ASD) splice patterns (SP) for CHD3 (see all 27) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | ^ | 14 | ^ | 15a | · | 15b | · | 15c | ^ | 16a | · | 16b | ^ | 17a | · | 17b | · | 17c | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 18a | · | 18b | ^ | 19 | ^ | 20 | ^ | 21a | · | 21b | · | 21c | ^ | 22a | · | 22b | ^ | 23a | · | 23b | · | 23c | · | 23d | ^ | 24a | · | 24b | · | 24c | ^ | 25a | · | 25b | ^ | 26a | · | 26b | ^ | 27 | ^ | 28a | · | 28b | · | 28c | ^ | 29 | ^ | 30 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | |
| ExUns: | 31a | · | 31b | ^ | 32a | · | 32b | ^ | 33a | · | 33b | ^ | 34a | · | 34b | ^ | 35a | · | 35b | · | 35c | ^ | 36a | · | 36b | · | 36c | ^ | 37a | · | 37b | · | 37c | · | 37d | ^ | 38 | ^ | 39a | · | 39b |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CHD3
|
Expression
for CHD3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CHD3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCGAACCCCC
About this image
See CHD3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CHD3
SOURCE GeneReport for Unigene cluster: Hs.25601
UniProtKB/Swiss-Prot: CHD3_HUMAN, Q12873Tissue specificity: Widely expressed
SABiosciences Expression via Pathway-Focused PCR Array including CHD3:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHD3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CHD3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHD3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHD3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHD3 |
Orthologs
for CHD3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CHD3 gene from 6/21 species (see all 21) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
CHD36 |
-- |
87(a) |
1 ↔ 1 |
GL343784.1(59587-105009) |
zebrafish
(Danio rerio) |
Actinopterygii |
chd31 |
chromodomain helicase DNA binding protein 3 |
71.83(n)
77.87(a) |
|
568230 XM_691549.5 XP_696641.3 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Mi-23 |
chromatin assembly/disassembly ATP dependent
DNA more |
61(a)
(best of 2) |
|
-- |
worm
(Caenorhabditis elegans) |
Secernentea |
chd-36let-4186 |
LEThal family member (let-418) |
48(a)47(a) |
possible orthologpossible ortholog |
X(12846360-12852531) V(5826816-5832844) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
PKR26GYM6 |
CHD3-type chromatin-remodeling factor PICKLE |
35(a)34(a) |
many ↔ manymany ↔ many |
4(15431350-15438678) 2(10713807-10723986) |
rice
(Oryza sativa) |
Liliopsida |
---- |
CHD3-type chromatin-remodeling factor PICKLE, puta...CHD3-type chromatin-remodeling factor PICKLE, puta... |
36(a)27(a) |
1 ↔ manypossible ortholog |
6(4166230-4182941) 1(38227769-38236185) |
ENSEMBL Gene Tree for CHD3 (if available)
TreeFam Gene Tree for CHD3 (if available) |
Paralogs
for CHD3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CHD3 gene
- CHD62 CHD52 CHD92 CHD42 CHD12 CHD72 CHD82 CHD22
9 SIMAP similar genes for CHD3 using alignment to 9 protein entries: CHD3_HUMAN (see all proteins):DKFZp434K213 DKFZp434P202 CHD5 CHD4 AIRE CHD1L
SMARCA5 HELLS SMARCA1
CHD3 for paralogs About GeneDecksing
|
Genomic Variants
for CHD3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CHD3 (7788123 - 7816078 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CHD3: --
Human Gene Mutation Database (HGMD): CHD3
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHD3 |
|
Disorders
/ Diseases
for CHD3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CHD3 for disorders About GeneDecksing
OMIM gene information: 602120
OMIM disorders: --
5  diseases for CHD3: About MalaCardsdermatomyositis huntington's disease hematopoiesis breast cancer
retinitis
Export disorders for CHD3 gene to outside databases
|
Publications
for CHD3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CHD3 gene, integrated from 9 sources (see all 76):
(articles sorted by number of sources associating them with CHD3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of the CHD family of proteins. (PubMed id 9326634)1, 2, 3 Woodage T.... Collins F.S. (1997)
- Molecular analysis of a major antigenic region of the 240 kD protein of Mi-2 autoantigen. (PubMed id 7560064)1, 2, 3 Ge Q.... Targoff I.N. (1995)
- Identification of a human 17p-located cDNA encoding a protein of the Snf2-like helicase family. (PubMed id 9688266)1, 2, 9 Aubry F.... Galibert F. (1998)
- Characterization of a new family of proteins that interact with the C-terminal region of the chromatin-remodeling factor CHD-3. (PubMed id 12505151)1, 2, 9 Lemos T.A.... Kobarg J. (2003)
- Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex. (PubMed id 9804427)1, 2, 9 Tong J.K....Schreiber S.L. (1998)
- Chromatin remodeling proteins interact with pericentrin to regulate centrosome integrity. (PubMed id 17626165)1, 2 Sillibourne J.E....Doxsey S.J. (2007)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2alpha subunit of NuRD. (PubMed id 11230151)1, 2 Schultz D.C.... Rauscher F.J. III (2001)
- The C-terminal region of CHD3/ZFH interacts with the CIDD region of the Ets transcription factor ERM and represses transcription of the human presenilin 1 gene. (PubMed id 17489097)1, 9 Pastorcic M. and Das H.K. (2007)
- Association of the nucleocapsid protein of the Seoul and Hantaan hantaviruses with small ubiquitin-like modifier-1-related molecules. (PubMed id 14609633)1, 9 Lee B.H....Arikawa J. (2003)
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External Searches for CHD3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing CHD3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing CHD3 gene
(According to HUGE)
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Specialized Databases showing CHD3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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About This Section
| Patent Information for CHD3 gene:
Search GeneIP for patents involving CHD3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for CHD3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | OriGene Antibodies for CHD3 | | OriGene shRNA RFP for CHD3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CHD3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHD3 | | | OriGene Protein Over-expression Lysate for CHD3 | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for CHD3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHD3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHD3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CHD3 | | OriGene Custom Protein Services for CHD3 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CHD3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHD3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHD3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CHD3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHD3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHD3 |
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| | Antibodies & Assays for CHD3 (CHD-3) |
| | | | Search Tocris compounds for CHD3 |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHD3 |
|  |  |  | | | | ThermoFisher Antibody for CHD3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHD3 |
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