CHD2 Gene
protein-coding GIFtS: 59
GCID: GC15P093924
|
|
chromodomain helicase DNA binding protein 2
| |
Aliases
for CHD2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromodomain Helicase DNA Binding Protein 21 2 | | DKFZp781D17271 | | CHD-22 3 | | FLJ386141 | | ATP-Dependent Helicase CHD22 3 | | Chromodomain-Helicase-DNA-Binding Protein 22 | | DKFZp547I13151 | | EC 3.6.4.123 | | DKFZp686E012001 | | EC 3.6.18 |
Export aliases for CHD2 gene to outside databasesPrevious GC identifers: GC15P089886 GC15P087276 GC15P091030 GC15P091173 GC15P091244 GC15P093443 GC15P069580 GC15P093533 |
Summaries
for CHD2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CHD2:
The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains andSNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structurethus altering access of the transcriptional apparatus to its chromosomal DNA template. Alternatively splicedtranscript variants encoding distinct isoforms have been found for this gene. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: CHD2_HUMAN, O14647Function: Sequence-selective DNA-binding protein (By similarity)
Gene Wiki entry for CHD2
|
Genomic Views
for CHD2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010274.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CHD2 gene promoter:
E2F-4 E2F-3a E2F-5 Pax-5 Pbx1a E2F-2 E2F-1 E2F PPAR-gamma2 CBF(2)
Other transcription factors
Search SABiosciences Chromatin IP Primers for CHD2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHD2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q26 Ensembl cytogenetic band: 15q26.1 HGNC cytogenetic band: 15q26CHD2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15P093924: view genomic region
(about GC identifiers)
Start:
|
93,425,937 bp from pter |
End:
|
93,571,237 bp from pter |
Size:
|
145,301 bases |
Orientation:
|
plus strand |
|
Proteins
for CHD2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CHD2_HUMAN, O14647 (See
protein sequence)Recommended Name: Chromodomain-helicase-DNA-binding protein 2 Size: 1828 amino acids; 211344 Da
Subcellular location: Nucleus (By similarity)
Secondary accessions: C6G482 Q96IP5Alternative splicing: 3 isoforms: O14647-1 O14647-2 O14647-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for CHD2: NX_O14647
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O14647
4/14 DME Specific Peptides for CHD2 (O14647) (see all 14)
CHD2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001036037.1 NP_001262.3
ENSEMBL proteins: ENSP00000451964 ENSP00000377747 ENSP00000451366 ENSP00000406581 ENSP00000443618 ENSP00000457493 ENSP00000464078 ENSP00000462080 ENSP00000451539
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
CHD2 for ontologies About GeneDecksing
CHD2 Antibody Products:
Assay Products for CHD2: |
Protein
Domains /
Families
for CHD2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CHD2 for domains About GeneDecksing
5/8 InterPro domains/families (see all 8):Graphical View of Domain Structure for InterPro Entry O14647ProtoNet protein and cluster: O14647 3 Blocks protein families: IPB000330 SNF2 related domain IPB000953 Chromo domain IPB002464 ATP-dependent helicase
UniProtKB/Swiss-Prot: CHD2_HUMAN, O14647Similarity: Belongs to the SNF2/RAD54 helicase familySimilarity: Contains 2 chromo domainsSimilarity: Contains 1 helicase ATP-binding domainSimilarity: Contains 1 helicase C-terminal domain |
Function
for CHD2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CHD2_HUMAN, O14647Function: Sequence-selective DNA-binding protein (By similarity)Catalytic activity: ATP + H(2)O = ADP + phosphate Genatlas biochemistry entry for CHD2:DNA binding protein with two chromatin organization (chromo) domains,and a helicase domain,2,component of the chromatinremodeling complex
Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.121
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHD2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHD2 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): CHD2 (NM_001042572) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CHD2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHD2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHD2 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
CHD2 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for CHD2:
Animal Models:
15/17 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Chd2) (see all 17):
CHD2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for CHD2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Chromatin Regulation / Acetylation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Cell Signaling Technology (CST) Pathway for CHD2
CHD2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CHD2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 8)
5/115 Interacting proteins for CHD2 (O146473 ENSP000003777474) via UniProtKB, MINT, STRING, and/or I2D (see all 115)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006357 | regulation of transcription from RNA polymerase II promoter |
TAS | 9326634 |
CHD2 for ontologies About GeneDecksing
|
Drugs & Compounds
for CHD2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CHD2
Search CenterWatch for drugs/clinical trials and news about CHD2
|
Transcripts
for CHD2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CHD2 gene (2 alternative transcripts): NM_001042572.2 NM_001271.3 Unigene Cluster for CHD2: Chromodomain helicase DNA binding protein 2 Hs.220864 [show with all ESTs]Unigene Representative Sequence: NM_00127118/28 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 28): ENST00000557682(uc021svn.1 uc021svo.1) ENST00000553829 ENST00000556895
ENST00000554669 ENST00000554894 ENST00000557147 ENST00000556722 ENST00000554133(uc021svp.1)
ENST00000555227 ENST00000556930(uc002bsm.2) ENST00000555520 ENST00000394196(uc002bsp.3)
ENST00000557381(uc002bso.1 uc010bog.1 uc010boh.1) ENST00000309818(uc010bof.1)
ENST00000554771 ENST00000420239(uc002bsn.3) ENST00000554122 ENST00000536619(uc010urb.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHD2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHD2 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): CHD2 (NM_001042572) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CHD2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHD2 |
Additional cDNA sequence: AF006514.1 AK095933.1 AK292850.1 AK295909.1 AL831836.1 AY429527.1 AY429528.1 BC007347.2 BC020810.1 BC047036.1 BC107885.1 BT007050.1 BX537626.1 DQ088985.1 DQ088986.1 24/34 DOTS entries (see all 34): DT.100790972 DT.117856 DT.446753 DT.101980110 DT.99986571 DT.100790974 DT.121015088 DT.92030314 DT.86849583 DT.95277798 DT.425664 DT.97795333 DT.121015159 DT.121014996 DT.91684353 DT.92426245 DT.92426248 DT.92448728 DT.100024532 DT.100024533 DT.100717033 DT.121015036 DT.121015109 DT.40259495 24/246 AceView cDNA sequences (see all 246): AI383601 BU684575 AI192651 BF197825 BQ000695 BX499837 AU117528 AA371331 BU076099 BF445982 AI017233 BC020810 BT007050 BF116059 AW168274 BU072111 AI066439 CB155469 BX494346 BF109187 NM_001271 BM724076 BX487907 BF792482
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for CHD2 (see all 8) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | ^ | 15 | ^ | 16 | ^ | 17a | · | 17b | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ |
|---|
|
| SP1: | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 22 | ^ | 23 | ^ | 24 | ^ | 25 | ^ | 26 | ^ | 27 | ^ | 28 | ^ | 29 | ^ | 30 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CHD2
|
Expression
for CHD2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CHD2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCAAGGGTCC
About this image
See CHD2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CHD2
SOURCE GeneReport for Unigene cluster: Hs.220864
SABiosciences Expression via Pathway-Focused PCR Array including CHD2:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHD2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CHD2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHD2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHD2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHD2 |
Orthologs
for CHD2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CHD2 gene from 9/29 species (see all 29) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
CHD21 |
chromodomain helicase DNA binding protein 2 |
80.61(n)
89.46(a) |
|
415507 XM_413879.3 XP_413879.3 |
lizard
(Anolis carolinensis) |
Reptilia |
CHD26 |
-- |
81(a) |
1 ↔ 1 |
GL343392.1(882188-944038) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.33422 |
Xenopus laevis transcribed sequence with moderate similarity more |
78.47(n) |
|
48047023 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.152422 |
Transcribed sequence with moderate similarity to protein more |
77.46(n) |
|
BM156218.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Chd11 , 3 |
chromatin binding3
Chromodomain-helicase-DNA-binding protein 11 |
54(a)3
53.02(n)1
49.59(a)1 |
|
2 23C43
335051 NM_057849.41 NP_477197.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
H06O01.23 |
chromodomain-helicase-DNA-biniding protein |
53(a) |
|
I(7017609-7023274) -- |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
CHD11 |
Chd1p |
48.26(n)
38.75(a) |
|
856911 NP_011091.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
CHR51 |
chromatin remodeling 5 |
49.66(n)
43.41(a) |
|
815823 NM_126926.4 NP_178970.3 |
rice
(Oryza sativa) |
Liliopsida |
NM_186008.12 |
-- |
74.5(n) |
|
NM_186008.1 |
ENSEMBL Gene Tree for CHD2 (if available)
TreeFam Gene Tree for CHD2 (if available) |
Paralogs
for CHD2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CHD2 gene
- CHD62 CHD52 CHD92 CHD42 CHD12 CHD72 CHD82 CHD32
13 SIMAP similar genes for CHD2 using alignment to 8 protein entries: CHD2_HUMAN (see all proteins):DKFZp781D1727 CHD5 CHD9 CHD1 SMARCA4 C17orf64
SMARCA5 CHD1L DKFZp434P202 HELLS DKFZp434K213 SMARCA1
CBX5
CHD2 for paralogs About GeneDecksing
|
Genomic Variants
for CHD2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CHD2 (93425937 - 93571237 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 7 variations for CHD2
2 CNVs: 49621 102162
5 Indels: 41902 25584 40120 45384 61475
Human Gene Mutation Database (HGMD): CHD2
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHD2 |
|
Disorders
/ Diseases
for CHD2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CHD2 for disorders About GeneDecksing
OMIM gene information: 602119
OMIM disorders: --
8  diseases for CHD2: About MalaCardscongenital diaphragmatic hernia choanal atresia urinary bladder cancer hernia
coloboma hodgkin's lymphoma scoliosis malaria
1 disease from the University of Copenhagen DISEASES database for CHD2:Choanal atresia Human Genome Epidemiology (HuGE) Navigator: CHD2 (2 documents)
Export disorders for CHD2 gene to outside databases
|
Publications
for CHD2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CHD2 gene, integrated from 9 sources (see all 25):
(articles sorted by number of sources associating them with CHD2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of the CHD family of proteins. (PubMed id 9326634)1, 2, 3 Woodage T.... Collins F.S. (1997)
- Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)1, 2 Zody M.C....Nusbaum C. (2006)
- Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
- System-wide changes to SUMO modifications in response to heat shock. (PubMed id 19471022)1 Golebiowski F....Hay R.T. (2009)
- Proteomics analysis of nucleolar SUMO-1 target protei ns upon proteasome inhibition. (PubMed id 19596686)1 Matafora V....Bachi A. (2009)
- Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)2 Daub H.... Mann M. (2008)
|
External Searches for CHD2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CHD2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CHD2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CHD2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CHD2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CHD2 gene:
Search GeneIP for patents involving CHD2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for CHD2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CHD2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CHD2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHD2 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CHD2 | | OriGene 3'-UTR Clone for CHD2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHD2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHD2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CHD2 | | OriGene Custom Protein Services for CHD2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CHD2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHD2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHD2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CHD2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHD2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHD2 |
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| | Antibodies & Assays for CHD2 (CHD-2) |
| | | | Search Tocris compounds for CHD2 |
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 | | | CHD2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHD2 |
|  |  |  | | | | ThermoFisher Antibodies for CHD2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHD2 |
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