CHD1L Gene
protein-coding GIFtS: 56
GCID: GC01P146717
|
|
chromodomain helicase DNA binding protein 1-like
| |
Aliases
for CHD1L gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromodomain Helicase DNA Binding Protein 1-Like1 2 | | Amplified In Liver Cancer 12 | | ALC11 2 3 5 | | Chromodomain-Helicase-DNA-Binding Protein 1-Like2 | | Amplified In Liver Cancer Protein 12 3 | | EC 3.6.4.123 | | CHDL2 | | EC 3.6.18 |
Export aliases for CHD1L gene to outside databasesPrevious GC identifers: GC01U990222 GC01P143439 GC01P144058 GC01P144221 GC01P143939 GC01P145180 GC01P120126 |
Summaries
for CHD1L gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CHD1L:
This gene encodes a DNA helicase protein involved in DNA repair. The protein converts ATP to add poly(ADP-ribose) as itregulates chromatin relaxation following DNA damage. Several alternatively spliced transcripts variants have beendescribed for this gene. (provided by RefSeq, Jan 2012)
UniProtKB/Swiss-Prot: CHD1L_HUMAN, Q86WJ1Function: DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damagethrough interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyzenucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding
Gene Wiki entry for CHD1L
|
Genomic Views
for CHD1L gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_167185.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CHD1L gene promoter:
STAT5B AML1a MyoD STAT5A NF-kappaB AREB6 Nkx6-1 NF-kappaB2 Msx-1 NF-kappaB1
Other transcription factors
Search SABiosciences Chromatin IP Primers for CHD1L
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHD1L |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q12 Ensembl cytogenetic band: 1q21.1 HGNC cytogenetic band: 1q21.1CHD1L Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P146717: view genomic region
(about GC identifiers)
Start:
|
146,714,291 bp from pter |
End:
|
146,767,443 bp from pter |
Size:
|
53,153 bases |
Orientation:
|
plus strand |
|
Proteins
for CHD1L gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CHD1L_HUMAN, Q86WJ1 (See
protein sequence)Recommended Name: Chromodomain-helicase-DNA-binding protein 1-like Size: 897 amino acids; 100984 Da
Subunit: Interacts with PARP1; interacts only when PARP1 is poly-ADP-ribosylated (PARylated)
Subcellular location: Nucleus. Note=Localizes at sites of DNA damage. Probably recruited to DNA damage sites byPARylated PARP1
Sequence caution: Sequence=BAB55248.1; Type=Frameshift; Positions=597;
Secondary accessions: A5YM64 Q53EZ3 Q5VXX7 Q6DD94 Q6PK83 Q86XH3 Q96HF7 Q96SP3 Q9BVJ1 Q9NVV8Alternative splicing: 4 isoforms: Q86WJ1-1 Q86WJ1-2 Q86WJ1-3 Q86WJ1-4 Explore the universe of human proteins at neXtProt for CHD1L: NX_Q86WJ1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q86WJ1
4/11 DME Specific Peptides for CHD1L (Q86WJ1) (see all 11)
CHD1L Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (5 alternative transcripts):
NP_001243265.1 NP_001243266.1 NP_001243267.1 NP_004275.4 NP_078844.2
ENSEMBL proteins: ENSP00000358262 ENSP00000389031 ENSP00000358263 ENSP00000355100
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
CHD1L for ontologies About GeneDecksing
CHD1L Antibody Products:
Assay Products for CHD1L: |
Protein
Domains /
Families
for CHD1L gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CHD1L for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q86WJ1ProtoNet protein and cluster: Q86WJ1 3 Blocks protein families: IPB000330 SNF2 related domain IPB002464 ATP-dependent helicase IPB002589 Protein of unknown function Appr-1
UniProtKB/Swiss-Prot: CHD1L_HUMAN, Q86WJ1Domain: The macro domain mediates non-covalent poly(ADP-ribose)-binding and recruitment to DNA damage sitesSimilarity: Belongs to the SNF2/RAD54 helicase familySimilarity: Contains 1 helicase ATP-binding domainSimilarity: Contains 1 helicase C-terminal domainSimilarity: Contains 1 Macro domain |
Function
for CHD1L gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CHD1L_HUMAN, Q86WJ1Function: DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damagethrough interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyzenucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-bindingCatalytic activity: ATP + H(2)O = ADP + phosphateEnzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.121
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHD1L (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHD1L (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CHD1L (NM_004284) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CHD1L | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHD1L |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHD1L |
Gene Ontology (GO): 5/8 molecular function terms (GO ID links to tree view) (see all 8): About this table
CHD1L for ontologies About GeneDecksing
Animal Models:
1 MGI phenotypic allele  for Chd1l (no phenotypes)
CHD1L for phenotypes About GeneDecksing
|
Pathways & Interactions
for CHD1L gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CHD1L
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/763 Interacting proteins for CHD1L (Q86WJ12, 3 ENSP000003582624) via UniProtKB, MINT, STRING, and/or I2D (see all 763)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| PRKDC | P785272, 3, ENSP000003134204 | MINT-7945693 MINT-7947479 I2D:
score=1 STRING: ENSP00000313420 | | API5 | Q9BZZ52, 3, ENSP000003993414 | MINT-7945693 I2D:
score=1 STRING: ENSP00000399341 | | PARP1 | P098742, 3, ENSP000003557594 | MINT-7947479 I2D:
score=1 STRING: ENSP00000355759 | | SUPT16H | Q9Y5B92, 3, ENSP000002162974 | MINT-7947479 I2D:
score=1 STRING: ENSP00000216297 | | EIF4A1 | P608422, 3, ENSP000002938314 | MINT-7945693 MINT-7947479 I2D:
score=1 STRING: ENSP00000293831 |
About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
CHD1L for ontologies About GeneDecksing
|
Drugs & Compounds
for CHD1L gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CHD1L
Search CenterWatch for drugs/clinical trials and news about CHD1L
|
Transcripts
for CHD1L gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CHD1L gene (5 alternative transcripts): NM_001256336.1 NM_001256337.1 NM_001256338.1 NM_004284.4 NM_024568.2 Unigene Cluster for CHD1L: Chromodomain helicase DNA binding protein 1-like Hs.191164 [show with all ESTs]Unigene Representative Sequence: NM_0042849 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000488864 ENST00000369258(uc001epm.4 uc001epn.4 uc010ozo.2 uc010ozp.2 uc009wji.3)
ENST00000467213(uc010ozq.1 uc009wjg.3) ENST00000492728 ENST00000485113
ENST00000469625 ENST00000431239(uc009wjh.3) ENST00000369259(uc001epo.4)
ENST00000361293
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHD1L (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHD1L (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CHD1L (NM_004284) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CHD1L | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHD1L |
Additional cDNA sequence: AF054177.1 AF537213.1 AK001342.1 AK026183.1 AK027631.1 AK223496.1 AK293157.1 AK297135.1 AK298424.1 AK303196.1 AK307400.1 BC001171.1 BC005038.1 BC008649.1 BC043501.1 BC053354.1 BC077717.1 CR749729.1 EF560738.1 NR_046070.1 XR_110824.3 24/30 DOTS entries (see all 30): DT.102839184 DT.445087 DT.99955880 DT.91747138 DT.207954 DT.40286524 DT.100027596 DT.100795921 DT.455144 DT.121342654 DT.86848913 DT.100795925 DT.95262341 DT.100001336 DT.102826585 DT.121342596 DT.121342748 DT.75119316 DT.91747131 DT.92045039 DT.100027597 DT.100657655 DT.102839182 DT.75195946 24/229 AceView cDNA sequences (see all 229): BE550268 D17100 BG493799 BF931258 N46402 AA573217 CB119739 AI677643 BG231737 BF931260 AI540539 BX110536 AI969160 BE894366 AA907338 BQ774866 CB961717 AW082853 AK001342 CD743205 AA417719 BX496347 AA493155 CF127503
GeneLoc Exon Structure
5/15 Alternative Splicing Database (ASD) splice patterns (SP) for CHD1L (see all 15) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | · | 11c | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | - | | | | - | | | | - | | | | - | | - | | | | |
| SP2: | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | - | | | | | | - | | | | - | | | | - | | | | - | | - | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | | | |
| SP4: | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | - | | | | - | | | | - | | | | - | | - | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | - | | | | | | - | | | | - | | | | - | | | | | | | | | |
| ExUns: | 14c | ^ | 15 | ^ | 16 | ^ | 17a | · | 17b | · | 17c | ^ | 18 | ^ | 19 | ^ | 20a | · | 20b | ^ | 21 | ^ | 22 | ^ | 23a | · | 23b | ^ | 24 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CHD1L
|
Expression
for CHD1L gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CHD1L expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCACGAAAGG
About this image
See CHD1L Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CHD1L
SOURCE GeneReport for Unigene cluster: Hs.191164
UniProtKB/Swiss-Prot: CHD1L_HUMAN, Q86WJ1Tissue specificity: Frequently overexpressed in hepatomacellular carcinomas
SABiosciences Custom PCR Arrays for CHD1L
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHD1L
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CHD1L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHD1L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHD1L | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHD1L |
Orthologs
for CHD1L gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CHD1L gene from 5/20 species (see all 20) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
CHD1L1 |
chromodomain helicase DNA binding protein 1-like |
72.41(n)
72.95(a) |
|
418338 XM_416560.3 XP_416560.2 |
lizard
(Anolis carolinensis) |
Reptilia |
CHD1L6 |
-- |
68(a) |
1 ↔ 1 |
2(82699974-82747196) |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc560842 |
similar to chromodomain helicase DNA binding protein more |
74.92(n) |
|
393283 BC050498.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT2G449801 |
SNF2 and helicase domain-containing protein |
51.15(n)
44.9(a) |
|
819106 NM_201960.2 NP_973689.2 |
rice
(Oryza sativa) |
Liliopsida |
Os03g01017001 |
hypothetical protein |
47.84(n)
41.18(a) |
|
4331290 NM_001055191.1 NP_001048656.1 |
ENSEMBL Gene Tree for CHD1L (if available)
TreeFam Gene Tree for CHD1L (if available) |
Paralogs
for CHD1L gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for CHD1L gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CHD1L (146714291 - 146767443 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for CHD1L
1 CNV: 1326
1 Inversion: 29494
Human Gene Mutation Database (HGMD): CHD1L
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHD1L |
|
Disorders
/ Diseases
for CHD1L gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CHD1L for disorders About GeneDecksing
OMIM gene information: 613039
OMIM disorders: --
12  diseases for CHD1L: About MalaCardsliver cancer choanal atresia postcholecystectomy syndrome intrahepatic cholangiocarcinoma
fibrosarcoma of bone cholangiocarcinoma hypercholesterolemia fibrosarcoma
hepatocellular carcinoma esophagitis adenocarcinoma carcinoma
1 disease from the University of Copenhagen DISEASES database for CHD1L:Postcholecystectomy syndrome Human Genome Epidemiology (HuGE) Navigator: CHD1L (1 document)
Export disorders for CHD1L gene to outside databases
|
Publications
for CHD1L gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CHD1L gene, integrated from 9 sources (see all 33):
(articles sorted by number of sources associating them with CHD1L) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1. (PubMed id 19661379)1, 2, 9 Ahel D....Boulton S.J. (2009)
- Isolation and characterization of a novel oncogene, amplified in liver cancer 1, within a commonly amplified region at 1q21 in hepatocellular carcinoma. (PubMed id 18023026)1, 2 Ma N.-F.... Guan X.-Y. (2008)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full- length cDNA cloning. (PubMed id 9653160)1, 3 Mao M.... Chen Z. (1998)
- CHD1L: a new candidate gene for congenital anomalies o f the kidneys and urinary tract (CAKUT). (PubMed id 22146311)1 Brockschmidt A....Weber R.G. (2012)
- PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1. (PubMed id 23045548)1 Pines A....Mullenders L. (2012)
- Translationally controlled tumor protein induces mitot ic defects and chromosome missegregation in hepatocellular carcinoma development . (PubMed id 21953552)1 Chan T.H....Guan X.Y. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Understanding the impact of 1q21.1 copy number variant . (PubMed id 21824431)1 Harvard C....Rajcan-Separovic E. (2011)
|
External Searches for CHD1L gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CHD1L gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CHD1L gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CHD1L gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
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About This Section
| Patent Information for CHD1L gene:
Search GeneIP for patents involving CHD1L
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for CHD1L gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CHD1L | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CHD1L | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHD1L | | | OriGene Protein Over-expression Lysate for CHD1L | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CHD1L | | OriGene 3'-UTR Clone for CHD1L | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHD1L | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHD1L | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for CHD1L | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CHD1L | | OriGene Custom Protein Services for CHD1L | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CHD1L | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHD1L | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHD1L | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CHD1L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHD1L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHD1L |
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| | | | Search Tocris compounds for CHD1L |
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 | | | CHD1L Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHD1L |
|  |  |  | | | | Search ThermoFisher Antibodies for CHD1L |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHD1L |
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