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CHCHD7 Gene

protein-coding   GIFtS: 48
GCID: GC08P057124

Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 7

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 71 2
COX23 Cytochrome C Oxidase Assembly Homolog (S. Cerevisiae)1
COX232
Coiled-Coil-Helix-Coiled-Coil-Helix Domain-Containing Protein 72
COX23 Cytochrome C Oxidase Assembly Homolog2

External Ids:    HGNC: 283141   Entrez Gene: 791452   Ensembl: ENSG000001707917   OMIM: 6112385   UniProtKB: Q9BUK03   

Export aliases for CHCHD7 gene to outside databases

Previous GC identifers: GC08P057174 GC08P057286 GC08P052591


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CHCHD7 Gene:
CHCHD7 (coiled-coil-helix-coiled-coil-helix domain containing 7) is a protein-coding gene. Diseases associated with CHCHD7 include pleomorphic adenoma, and adenoma.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000008.11  NT_008183.20  NC_018919.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CHCHD7 gene promoter:
         AML1a   Pbx1a   POU3F2 (N-Oct-5b)   POU3F2 (N-Oct-5a)   HNF-3beta   POU3F2   Evi-1   STAT3   LyF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCHCHD7 promoter sequence
   Search Chromatin IP Primers for CHCHD7

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CHCHD7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q12.1   Ensembl cytogenetic band:  8q12.1   HGNC cytogenetic band: 8q11.23

CHCHD7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CHCHD7 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P057124:  view genomic region     (about GC identifiers)

Start:
57,124,245 bp from pter      End:
57,131,357 bp from pter
Size:
7,113 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: CHCH7_HUMAN, Q9BUK0 (See protein sequence)
Recommended Name: Coiled-coil-helix-coiled-coil-helix domain-containing protein 7  
Size: 85 amino acids; 10095 Da
Subunit: Monomer
Sequence caution: Sequence=EAW86776.1; Type=Erroneous gene model prediction;
1 PDB 3D structure from and Proteopedia for CHCHD7:
2LQT (3D)    
Secondary accessions: A8K223 E9PBH3 J3KNE9 Q7Z588
Alternative splicing: 5 isoforms:  Q9BUK0-1   Q9BUK0-2   Q9BUK0-3   Q9BUK0-4   Q9BUK0-5   (Gene prediction based on EST data)

Explore the universe of human proteins at neXtProt for CHCHD7: NX_Q9BUK0

Explore proteomics data for CHCHD7 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CHCHD7 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (6 alternative transcripts): 
    NP_001011667.1  NP_001011668.1  NP_001011669.1  NP_001011670.1  NP_001011671.1  NP_077276.2  

    ENSEMBL proteins: 
     ENSP00000429635   ENSP00000347469   ENSP00000429230   ENSP00000430350   ENSP00000430498  
     ENSP00000429217   ENSP00000430714   ENSP00000428274   ENSP00000428917   ENSP00000379949  
     ENSP00000430882   ENSP00000430458   ENSP00000428095   ENSP00000306425  

    CHCHD7 Human Recombinant Protein Products:

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    Novus Biologicals CHCHD7 Lysate
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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CHCHD7

    CHCHD7 Antibody Products:

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    CHCHD7 Assay Products:

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    Cloud-Clone Corp. ELISAs for CHCHD7
    Cloud-Clone Corp. CLIAs for CHCHD7


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    CHCHD: Coiled-coil-helix-coiled-coil-helix domain containing

    1 InterPro protein domain:
     IPR009069 Cys_alpha_HP_mot_SF

    Graphical View of Domain Structure for InterPro Entry Q9BUK0

    ProtoNet protein and cluster: Q9BUK0

    UniProtKB/Swiss-Prot: CHCH7_HUMAN, Q9BUK0
    Similarity: Belongs to the CHCHD7 family
    Similarity: Contains 1 CHCH domain


    CHCHD7 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004129cytochrome-c oxidase activity ----
         
    CHCHD7 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CHCHD7
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CHCHD7
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CHCHD7

    miRNA
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    miRTarBase miRNAs that target CHCHD7:
    hsa-mir-124-3p (MIRT023163)

    Block miRNA regulation of human, mouse, rat CHCHD7 using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate CHCHD7:
    hsa-miR-3671 hsa-miR-4261 hsa-miR-155 hsa-miR-452*
    SwitchGear 3'UTR luciferase reporter plasmidCHCHD7 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CHCHD7
    Predesigned siRNA for gene silencing in human, mouse, rat CHCHD7

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CHCHD7

    Clone
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    OriGene clones in human, mouse for CHCHD7 (see all 31)
    OriGene ORF clones in mouse, rat for CHCHD7
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    GenScript: all cDNA clones in your preferred vector (see all 6): CHCHD7 (NM_024300)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CHCHD7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHCHD7

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for CHCHD7
    Browse ESI BIO Cell Lines and PureStem Progenitors for CHCHD7 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHCHD7


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CHCH7_HUMAN, Q9BUK0: Mitochondrion intermembrane space (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular3
    mitochondrion3
    nucleus3

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005758mitochondrial intermembrane space IEA--

    CHCHD7 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CHCHD7
    Interactions:

        Search GeneGlobe Interaction Network for CHCHD7

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for CHCHD7 (ENSP000003064254) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ZC3H14ENSP000002510384STRING: ENSP00000251038
    SETD2ENSP000003867594STRING: ENSP00000386759
    COPS5ENSP000003505124STRING: ENSP00000350512
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CHCHD7 (CHCH7)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for CHCHD7 gene (6 alternative transcripts): 
    NM_001011667.1  NM_001011668.1  NM_001011669.1  NM_001011670.1  NM_001011671.1  NM_024300.3  

    Unigene Cluster for CHCHD7:

    Coiled-coil-helix-coiled-coil-helix domain containing 7
    Hs.436913  [show with all ESTs]
    Unigene Representative Sequence: AK098285
    18 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000521831 ENST00000355315 ENST00000518169 ENST00000522366 ENST00000517636
    ENST00000517933 ENST00000523532 ENST00000523667 ENST00000521982 ENST00000522166
    ENST00000518801(uc003xss.3 uc003xsw.3) ENST00000523975 ENST00000396723
    ENST00000523061 ENST00000521524 ENST00000519367 ENST00000518944 ENST00000303759(uc003xsu.3 uc003xsv.3 uc003xst.3 uc003xsx.3)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CHCHD7 using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate CHCHD7:
    hsa-miR-3671 hsa-miR-4261 hsa-miR-155 hsa-miR-452*
    SwitchGear 3'UTR luciferase reporter plasmidCHCHD7 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CHCHD7
    Predesigned siRNA for gene silencing in human, mouse, rat CHCHD7
    Clone
    Products:
         
    OriGene clones in human, mouse for CHCHD7 (see all 31)
    OriGene ORF clones in mouse, rat for CHCHD7
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 6): CHCHD7 (NM_024300)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CHCHD7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHCHD7
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for CHCHD7
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CHCHD7
      QuantiTect SYBR Green Assays in human, mouse, rat CHCHD7
      QuantiFast Probe-based Assays in human, mouse, rat CHCHD7

    Additional mRNA sequence: 

    AK095922.1 AK098285.1 AK225982.1 AK290088.1 AY070434.1 BC002546.2 

    15 DOTS entries:

    DT.92465096  DT.100790363  DT.100790364  DT.92465118  DT.91747597  DT.121466615  DT.95180572  DT.95180567 
    DT.100790368  DT.100659225  DT.92465110  DT.100790366  DT.121466593  DT.121466605  DT.95180566 

    Selected AceView cDNA sequences (see all 169):

    BP347201 CB163742 BU166912 CA448281 NM_024300 BE888913 BQ056185 AK095922 
    BU619854 AW470010 AV709532 AA355514 AI624536 T25371 BQ003903 BG677035 
    BU949066 AI970828 CR601205 AA047772 CB154085 BX480945 BC002546 AW149296 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CHCHD7 (see all 17)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c ^ 3a · 3b · 3c · 3d ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b · 6c · 6d · 6e · 6f · 6g · 6h · 6i ·
    SP1:                                            -     -     -           -                 -           -                                                         
    SP2:                                            -     -     -           -                             -                                                         
    SP3:                                            -     -     -           -     -                       -                                                         
    SP4:                                      -     -     -     -           -                       -     -                                                         
    SP5:                                      -     -     -     -           -     -                 -     -                                                         

    ExUns: 6j · 6k
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for CHCHD7

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CHCHD7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACCTTGATTG
    CHCHD7 Expression
    About this image


    CHCHD7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Ovary (Reproductive System)
             Ovarian Somatic Cells Ovigerous Cord
    CHCHD7 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CHCHD7 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.436913
        Custom PCR Arrays for CHCHD7
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for CHCHD7
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CHCHD7
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    QuantiFast Probe-based Assays in human, mouse, rat CHCHD7
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHCHD7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for CHCHD7 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Chchd71 , 5 coiled-coil-helix-coiled-coil-helix domain containing more1, 5 87.06(n)1
    82.35(a)1
      4 (2.20 cM)5
    664331  NM_001190323.21  NP_001177252.11 
     39388885 
    chicken
    (Gallus gallus)
    Aves CHCHD71 coiled-coil-helix-coiled-coil-helix domain containing more 70(n)
    58.75(a)
      770709  XM_001234039.3  XP_001234040.1 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia chchd71 coiled-coil-helix-coiled-coil-helix domain containing more 62.75(n)
    52.94(a)
      549844  NM_001017090.1  NP_001017090.1 
    zebrafish
    (Danio rerio)
    Actinopterygii chchd71 coiled-coil-helix-coiled-coil-helix domain containing more 61.85(n)
    53.01(a)
      561510  NM_001127186.2  NP_001120658.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG41866
    --
    39(a)
    1 ↔ 1
    3L(20762686-20763180)


    ENSEMBL Gene Tree for CHCHD7 (if available)
    TreeFam Gene Tree for CHCHD7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CHCHD7 gene

    CHCHD7 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for CHCHD7
    PGOHUM00000246851


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CHCHD7 (see all 133)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs349693641,2
    C--57125952(+) TTTTT-/TGAGAC 6 -- int12Minor allele frequency- T:0.25NA 4
    rs1496186661,2
    --57125974(+) ACGGCA/GTCTTC 6 -- int10--------
    rs1121359411,2
    C,F--57126082(+) AGTAGC/TTGGGA 6 -- int12Minor allele frequency- T:0.50WA CSA 4
    rs1468509371,2
    C--57126138(+) TAGAC-/AGGGGGT 6 -- int10--------
    rs1395612751,2
    --57126293(+) CGCAGA/GGAAAT 6 -- int10--------
    rs1178696381,2
    C,F--57126300(+) AAATAG/ATTAAA 6 -- int11Minor allele frequency- A:0.01NA 120
    rs735962341,2
    C--57126336(+) TTCAAC/TTCTTT 6 -- int11Minor allele frequency- T:0.50WA 2
    rs1886100221,2
    --57126385(+) AGCAAA/TAACTT 6 -- int10--------
    rs1450906911,2
    --57126485(+) TGTACA/CGAATT 6 -- int10--------
    rs1932688511,2
    --57126507(+) TTGTAC/TGCTAA 6 -- int10--------

    HapMap Linkage Disequilibrium report for CHCHD7 (57124245 - 57131357 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for CHCHD7: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CHCHD7
    DNA2.0 Custom Variant and Variant Library Synthesis for CHCHD7

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611238    OMIM disorders: --

    UniProtKB/Swiss-Prot: CHCH7_HUMAN, Q9BUK0
  • Note=A chromosomal aberration involving CHCHD7 is found in salivary gland pleiomorphic adenomas, the most
    common benign epithelial tumors of the salivary gland. Translocation t(6;8)(p21.3-22;q13) with PLAG1

  • 4 diseases for CHCHD7:    
    About MalaCards
    pleomorphic adenoma    adenoma    multiple myeloma    myeloma

    1 disease from the University of Copenhagen DISEASES database for CHCHD7:
    Pleomorphic adenoma

    CHCHD7 for disorders           About GeneDecksing

    Genetic Association Database (GAD): CHCHD7
    Human Genome Epidemiology (HuGE) Navigator: CHCHD7 (3 documents)

    Export disorders for CHCHD7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CHCHD7 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with CHCHD7)
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    world of online information

    1. Structural characterization of CHCHD5 and CHCHD7: two atypical human twin CX9C proteins. (PubMed id 22842048)1, 2, 3 Banci L.... Winkelmann J. (J. Struct. Biol. 2012)
    2. The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature. (PubMed id 20546612)1, 4 Zhao J....Grant S.F. (BMC Med. Genet. 2010)
    3. Genome-wide analysis of eukaryotic twin CX9C proteins. (PubMed id 20922212)1, 3 Cavallaro G. (Mol Biosyst 2010)
    4. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    5. Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966. (PubMed id 19266077)1, 4 Sovio U....Jarvelin M.R. (PLoS Genet. 2009)
    6. Many sequence variants affecting diversity of adult human height. (PubMed id 18391951)1, 4 Gudbjartsson D.F....Stefansson K. (Nat. Genet. 2008)
    7. Identification of ten loci associated with height highlights new biological pathways in human growth. (PubMed id 18391950)1, 4 Lettre G.... Hirschhorn J.N. (Nat. Genet. 2008)
    8. CHCHD7-PLAG1 and TCEA1-PLAG1 gene fusions resulting from cryptic, intrachromosomal 8q rearrangements in pleomorphic salivary gland adenomas. (PubMed id 16736500)1, 2 Asp J.... Stenman G. (Genes Chromosomes Cancer 2006)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79145 HGNC: 28314 AceView: CHCHD7 Ensembl:ENSG00000170791 euGenes: HUgn79145
    ECgene: CHCHD7 H-InvDB: CHCHD7

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CHCHD7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CHCHD7 gene:
    Search GeneIP for patents involving CHCHD7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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