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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

CHCHD10 Gene

protein-coding GIFtS: 40
GCID: GC22M024109

coiled-coil-helix-coiled-coil-helix domain containing 1...

(Previous name: chromosome 22 open reading frame 16 )
(Previous symbol: C22orf16)

Explore 1 disease affiliated with
CHCHD10 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 10¹ ²
C22orf16¹ ² ³
N27C7-4¹ ²
Protein N27C7-4² ³
Chromosome 22 Open Reading Frame 16¹
Coiled-Coil-Helix-Coiled-Coil-Helix Domain-Containing Protein 10, Mitochondrial²

External Ids:	HGNC: 15559¹	Entrez Gene: 400916²	Ensembl: ENSG00000250479⁷	UniProtKB: Q8WYQ3³

Export aliases for CHCHD10 gene to outside databases

Previous GC identifers: GC22M022438 GC22M007096

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000022.10 NC_018933.1 NT_011520.12

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the CHCHD10 gene promoter:
Egr-3 AML1a p53 p300 MZF-1 CREB HOXA5 ARP-1 Meis-1a
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CHCHD10 promoter sequence

Search SABiosciences Chromatin IP Primers for CHCHD10

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHCHD10

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q11.23 Ensembl cytogenetic band: 22q11.23 HGNC cytogenetic band: 22q11.23

CHCHD10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CHCHD10 gene location

GeneLoc information about chromosome 22 GeneLoc Exon Structure

GeneLoc location for GC22M024109: view genomic region (about GC identifiers)

Start:	24,108,021 bp from pter	End:	24,110,630 bp from pter
Size:	2,610 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CHC10_HUMAN, Q8WYQ3 (See protein sequence)

Recommended Name: Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial precursor

Size: 142 amino acids; 14149 Da

Subcellular location: Mitochondrion (Potential)

Secondary accessions: A8K0J5

Explore the universe of human proteins at neXtProt for CHCHD10: NX_Q8WYQ3

CHCHD10 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_998885.1

ENSEMBL proteins:

ENSP00000430042 ENSP00000384973 ENSP00000418428 ENSP00000429411 ENSP00000429976

Human Recombinant Protein Products for CHCHD10:

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	Uscn Proteins for CHCHD10

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005739	mitochondrion	IDA	--

CHCHD10 for ontologies About GeneDecksing

CHCHD10 Antibody Products:

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Assay Products for CHCHD10:

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	Uscn ELISAs and CLIAs for CHCHD10

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

CHCHD10 for domains About GeneDecksing

1 InterPro domain/family:

IPR010625 CHCH

Graphical View of Domain Structure for InterPro Entry Q8WYQ3

ProtoNet protein and cluster: Q8WYQ3

1 Blocks protein family: IPB010625 CHCH

UniProtKB/Swiss-Prot: CHC10_HUMAN, Q8WYQ3

Similarity: Contains 1 CHCH domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003674	molecular_function	ND	--

CHCHD10 for ontologies About GeneDecksing

Phenotypes:
4 GenomeRNAi human phenotypes for CHCHD10:

Decreased Hepatitis C virus re

Decreased NANOG protein expres

Decreased OCT4 protein express

Decreased POU5F1-GFP protein e

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for CHCHD10

miRNA Products:		OriGene 3'-UTR Clone: CHCHD10 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CHCHD10
		7 QIAGEN miScript miRNA Assays for microRNAs that regulate CHCHD10:
		hsa-miR-92a hsa-miR-363 hsa-miR-25 hsa-miR-367 hsa-miR-599 hsa-miR-32 hsa-miR-92b
		SwitchGear 3'UTR luciferase reporter plasmid: CHCHD10 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHCHD10 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHCHD10 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: CHCHD10 (NM_213720)
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In Situ Assay
Products:

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for CHCHD10

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for CHCHD10

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006119	oxidative phosphorylation	IMP	--
GO:0006754	ATP biosynthetic process	IMP	--
GO:2000984	negative regulation of ATP citrate synthase activity	IMP	--

CHCHD10 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CHCHD10
Search CenterWatch for drugs/clinical trials and news about CHCHD10 / CHC10

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CHCHD10 gene:

NM_213720.1

Unigene Cluster for CHCHD10:

Coiled-coil-helix-coiled-coil-helix domain containing 10

Hs.66915 [show with all ESTs]

Unigene Representative Sequence: BM913730

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000520222 ENST00000401675 ENST00000484558(uc002zxw.3) ENST00000521886

ENST00000523865 ENST00000517886

miRNA Products:		OriGene 3'-UTR Clone: CHCHD10 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CHCHD10
		7 QIAGEN miScript miRNA Assays for microRNAs that regulate CHCHD10:
		hsa-miR-92a hsa-miR-363 hsa-miR-25 hsa-miR-367 hsa-miR-599 hsa-miR-32 hsa-miR-92b
		SwitchGear 3'UTR luciferase reporter plasmid: CHCHD10 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CHCHD10 (see all 4) OriGene shRNA RFP: CHCHD10 OriGene siRNA: CHCHD10
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CHCHD10
		Sirion Biotech Custom design and validation of potent shRNA sequences against CHCHD10

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHCHD10 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHCHD10 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: CHCHD10 (NM_213720)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for CHCHD10
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHCHD10

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHCHD10 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHCHD10
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHCHD10

Additional cDNA sequence:

AK289560.1 BC053570.1 BC065232.1

10 DOTS entries:

DT.95286692 DT.99991967 DT.97854234 DT.100029788 DT.95162988 DT.97791734 DT.91729410 DT.91973812

DT.95162987 DT.95162990

24/339 AceView cDNA sequences (see all 339):

AJ571994 AI253230 AA384942 AW779934 AI985252 BQ221514 AI201628 AI825600

AJ574577 BI517638 AA384858 AA295581 AA211613 CR594120 BU728410 BI711464

AI620416 AI356525 BC065232 BM310585 AI660959 BM708715 BC053570 BU078826

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CHCHD10 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTCTGAGCTC

About this image

CHCHD10 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Adipose

Interscapular Brown Adipose Depot

Adipose

Thoracic Perivascular Adipose

Adipose

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

Sox17-GFP genetically modified stem cells (Embryonic Stem Cell)

Early Embryo, Inner Cell Mass

Definitive endoderm-like cells (A scalable, suspensi...)

See CHCHD10 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CHCHD10

SOURCE GeneReport for Unigene cluster: Hs.66915

SABiosciences Custom PCR Arrays for CHCHD10

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHCHD10 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHCHD10
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHCHD10

In Situ
Assay Products:

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for CHCHD10

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals and fungi.

Orthologs for CHCHD10 gene from 7/22 species (see all 22) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Chchd10^{1 , 5}	coiled-coil-helix-coiled-coil-helix domain containing more^{1, 5}	85.51(n)¹ 86.96(a)¹		10 (38.62 cM)⁵ 103172¹ NM_175329.3¹ NP_780538.2¹ 75935573⁵
chicken (Gallus gallus)	Aves	LOC416933¹	coiled-coil-helix-coiled-coil-helix domain-containing more	68.94(n) 67.42(a)		416933 XM_003642222.1 XP_003642270.1
lizard (Anolis carolinensis)	Reptilia	CHCHD10⁶	--	62(a)	1 ↔ 1	LGb(2765750-2770852)
zebrafish (Danio rerio)	Actinopterygii	chchd10¹	coiled-coil-helix-coiled-coil-helix domain containing more	61.7(n) 66.67(a)		393757 NM_200784.1 NP_957078.1
fruit fly (Drosophila melanogaster)	Insecta	CG5010⁶ CG31008⁶ (see all 3)	--	38(a) 34(a) (see all 3)	many ↔ many many ↔ many (see all 3)	X(17043071-17044680) 3R(26815199-26815728)
worm (Caenorhabditis elegans)	Secernentea	har-1⁶	Hemiasterlin resistant protein 1	40(a)	1 → many	III(4152026-4152886)
baker's yeast (Saccharomyces cerevisiae)	Saccharomycetes	MIC17¹	Mic17p	46.46(n) 42.52(a)		855014 NP_013715.1

ENSEMBL Gene Tree for CHCHD10 (if available)
TreeFam Gene Tree for CHCHD10 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for CHCHD10 gene

CHCHD2²

2 SIMAP similar genes for CHCHD10 using alignment to 4 protein entries: CHC10_HUMAN (see all proteins):

CHCHD2 CHCHD2P9

CHCHD10 for paralogs About GeneDecksing

2 Pseudogenes.org Pseudogenes for CHCHD10
PGOHUM00000234155 PGOHUM00000233190

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 22 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs149955095^1,2		--	24108611(+)	`AGAGGC/TGGCTA`	1	--	int¹		0	--	--	--	--
rs192346887^1,2		--	24108619(+)	`CTACAA/GACAGC`	1	--	int¹		0	--	--	--	--
rs131440^1,2	C	--	24108639(+)	`CTGCC-/TTTTTT`	1	--	int¹		1		NA	2
rs9608181^1,2		--	24108701(+)	`gcggcG/Acagtc`	1	--	int¹		3		CSA NA EA	241
rs131441^1,2	C,A,H	--	24108756(+)	`TGCCTC/TGGCCT`	1	--	int¹		3		NA	6
rs6003876^1,2	C,A	--	24108803(+)	`cccaaG/Caaatt`	1	--	int¹		1		WA	2
rs131442^1,2	C,F,A,H	--	24108977(+)	`GCAGGG/AGAGGG`	1	--	int¹		24		NS EA NA WA CSA	2350
rs142121646^1,2		--	24109126(+)	`CTTACA/GGCGGT`	1	--	int¹		0	--	--	--	--
rs73396548^1,2	C,F	--	24109285(+)	`GGCGAG/ATCTCT`	1	--	int¹		4		NA CSA WA	242
rs73396549^1,2	C,F	--	24109409(+)	`GTGAAC/TTCAAG`	1	--	int¹		5		NA WA EA	362

HapMap Linkage Disequilibrium report for CHCHD10 (24108021 - 24110630 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CHCHD10: --

SABiosciences Cancer Mutation PCR Assays

Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHCHD10

DNA2.0 Custom Variant and Variant Library Synthesis for CHCHD10

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

CHCHD10 for disorders About GeneDecksing

1 disease for CHCHD10: About MalaCards

twinning

Human Genome Epidemiology (HuGE) Navigator: CHCHD10 (4 documents)

Export disorders for CHCHD10 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for CHCHD10 gene integrated from 9 sources:
(articles sorted by number of sources associating them with CHCHD10)

Utopia: connect your pdf to the dynamic
world of online information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Functional annotation of heart enriched mitochondrial genes GBAS and CHCHD10 through guilt by association. (PubMed id 20888800)¹ Martherus R.S....Ayoubi T.A. (2010)
Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)¹ Hendrickson S.L....O'Brien S.J. (2010)
Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)¹ Bailey S.D....Anand S. (2010)
Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)¹ Talmud P.J.... . (2009)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)¹ Barbe L....Andersson-Svahn H. (2008)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)² Ota T.... Sugano S. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )² Aoki H.... Hino O. (2000)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 400916	HGNC: 15559	AceView: C22orf16	Ensembl:ENSG00000250479	euGenes: HUgn400916
ECgene: CHCHD10	H-InvDB: CHCHD10

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for CHCHD10	Pharmacogenomics, SNPs, Pathways

Intellectual Property for CHCHD10 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for CHCHD10 gene:
Search GeneIP for patents involving CHCHD10

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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	Browse OriGene Antibodies		OriGene shRNA RFP for CHCHD10
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CHCHD10		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHCHD10
	OriGene Protein Over-expression Lysate for CHCHD10		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for CHCHD10		OriGene 3'-UTR Clone for CHCHD10
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHCHD10		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHCHD10
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
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	OriGene Custom Antibody Services for CHCHD10		OriGene Custom Protein Services for CHCHD10
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CHCHD10
	Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHCHD10
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHCHD10
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CHCHD10
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	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHCHD10

	GenScript Custom Purified and Recombinant Proteins Services for CHCHD10		GenScript cDNA clones with any tag delivered in your preferred vector for CHCHD10
	GenScript Custom Assay Services for CHCHD10		GenScript Custom Superior Antibodies Services for CHCHD10
	GenScript Custom overexpressing Cell Line Services for CHCHD10		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
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	Regulatory tfbs in CHCHD10 promoter
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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
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CHCHD10 Proteins, Antibodies, CLIAs, and ELISAs

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Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for CHCHD10

	SwitchGear 3'UTR luciferase reporter plasmids for CHCHD10
	SwitchGear Promoter luciferase reporter plasmids for CHCHD10

Search ThermoFisher Antibodies for CHCHD10

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHCHD10

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for CHCHD10

Sirion Biotech Customized:

	stable knockdown cell line services for CHCHD10
	inducible knockdown cell line services for CHCHD10
	design and validation of potent shRNA sequences against CHCHD10
	adenovirus for potent knockdown of CHCHD10
	adenovirus for overexpression of CHCHD10
	stable overexpressing cell line services for CHCHD10
	inducible overexpressing cell line services for CHCHD10

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 14 May 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes CHCHD10 gene at Home site.

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CHCHD10 Gene

coiled-coil-helix-coiled-coil-helix domain containing 1...

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CHCHD10 Gene

coiled-coil-helix-coiled-coil-helix domain containing 1...

Aliasesfor CHCHD10 gene

Summariesfor CHCHD10 gene

Genomic Viewsfor CHCHD10 gene

Proteinsfor CHCHD10 gene

Protein Domains /Familiesfor CHCHD10 gene

Functionfor CHCHD10 gene

Pathways & Interactionsfor CHCHD10 gene

Drugs & Compoundsfor CHCHD10 gene

Transcriptsfor CHCHD10 gene

Expression for CHCHD10 gene

Orthologsfor CHCHD10 gene

Paralogsfor CHCHD10 gene

Genomic Variantsfor CHCHD10 gene

Disorders / Diseasesfor CHCHD10 gene

Publicationsfor CHCHD10 gene

External Searches for CHCHD10 gene

Genome Databases showing CHCHD10 gene

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Aliases
for CHCHD10 gene

Summaries
for CHCHD10 gene

Genomic Views
for CHCHD10 gene

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for CHCHD10 gene

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Families
for CHCHD10 gene

Function
for CHCHD10 gene

Pathways & Interactions
for CHCHD10 gene

Drugs & Compounds
for CHCHD10 gene

Transcripts
for CHCHD10 gene

Expression
for CHCHD10 gene

Orthologs
for CHCHD10 gene

Paralogs
for CHCHD10 gene

Genomic Variants
for CHCHD10 gene

Disorders / Diseases
for CHCHD10 gene

Publications
for CHCHD10 gene

Intellectual Property
for CHCHD10 gene

Products
for CHCHD10 gene