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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CHAF1B Gene

protein-coding   GIFtS: 57
GCID: GC21P037757

chromatin assembly factor 1, subunit B (p60)
 Explore 7 diseases affiliated with
CHAF1B via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for CHAF1B    

Aliases
for CHAF1B gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, and/or 11Nature:405,311-319 and CroW21)
About This Section
Aliases
Chromatin Assembly Factor 1, Subunit B (P60)1 2     Chromatin Assembly Factor I P60 Subunit2 3
CAF1A1 2 3 5     CAF-1 Subunit B2 3
CAF1P601 2 3     CAF-I 60 KDa Subunit2 3
MPHOSPH71 2 3     CAF-I P602 3
MPP71 2 3     M-Phase Phosphoprotein 72 3
CAF-11 2     CAF-IP602
CAF11 2     Chromatin Assembly Factor 1 Subunit B2
Human Chromatin Assembly Factor-I P60 Subunit2 11     

External Ids:    HGNC: 19111   Entrez Gene: 82082   Ensembl: ENSG000001592597   OMIM: 6012455   UniProtKB: Q131123   

Export aliases for CHAF1B gene to outside databases

Previous GC identifers: GC21P034335 GC21P034418 GC21P036678 GC21P036679 GC21P023233


Summaries
for CHAF1B gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for CHAF1B:
Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I
is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60
subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated
in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is
released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA
repair. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: CAF1B_HUMAN, Q13112
Function: Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone
octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing
newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor
subsequent to DNA replication to complete the histone octamer. The CCR4-NOT complex functions as general transcription
regulation complex

Gene Wiki entry for CHAF1B


Genomic Views
for CHAF1B gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics, Whole Chromsome Sequence According to Nature (Cited Here with Permission):405,311-319 and CroW21)
About This Section
RefSeq DNA sequence:
NC_000021.8  NC_018932.1  NT_011512.11  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CHAF1B gene promoter:
         HFH-3   Nkx2-2   STAT5A   Tal-1beta   LCR-F1   E47   FOXI1   FAC1   E2F   E2F-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CHAF1B promoter sequence

   Search SABiosciences Chromatin IP Primers for CHAF1B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHAF1B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 21q22.13   Ensembl cytogenetic band:  21q22.12   HGNC cytogenetic band: 21q22.2
Nature(405: 311-319) cytogenetic band:   21q22.13
CHAF1B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CHAF1B gene location
GeneLoc information about chromosome 21         GeneLoc Exon Structure

(about GC identifiers)
GC21P037757:   GeneLoc Nature:405,311-319
Start:
 37,757,676 bp from pter       23,334,828 bp from centromere
End:
 37,789,125 bp from pter 23,365,571 bp from centromere
Size:
 31,450 bases 30,744 bases
Orientation:
 plus strand plus strand

Whole chromosome sequencing:
cDNA sequence: U20980
genomic clones: KB5G11


Proteins
for CHAF1B gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CAF1B_HUMAN, Q13112 (See protein sequence)
Recommended Name: Chromatin assembly factor 1 subunit B  
Size: 559 amino acids; 61493 Da
Subunit: Subunit of the CAF-1 complex that contains RBBP4, CHAF1B and CHAF1A. CHAF1A binds directly to CHAF1B. Only
minor amounts of RBBP4 are complexed with CHAF1A and CHAF1B in G1 phase. In G2 and S phase also monomeric CHAF1B is
detected. Subunit of the CCR4-NOT core complex that contains CHAF1A, CHAF1B, CNOT1, CNOT2, CNOT3, CNOT4, CNOT6 and
CNOT8
Subcellular location: Nucleus. Cytoplasm. Note=DNA replication foci. Cytoplasmic in M phase
Developmental stage: Active complex is found in G1, S and G2 phases
Secondary accessions: Q99548

Explore the universe of human proteins at neXtProt for CHAF1B: NX_Q13112

Post-translational modifications:

  • Differentially phosphorylated during cell cycle. During mitosis the p60 subunit of inactive CAF-1 is
    • hyperphosphorylated and displaced into the cytosol. Progressivly dephosphorylated from G1 to S and G2 phase.
    Phosphorylated p60 is recruited to chromatin undergoing DNA repair after UV irradiation in G1, S or G2 phases1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q13112

    • CHAF1B Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_005432.1  
    ENSEMBL proteins: 
     ENSP00000315700   ENSP00000446823  

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    Uscn Proteins for CHAF1B

    Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus NAS9614144
    GO:0005654colocalizes with nucleoplasm IDA16780588
    GO:0005678chromatin assembly complex ----
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm NAS9614144


    CHAF1B for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for CHAF1B

    Protein Domains /
    Families
    for CHAF1B gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    CHAF1B for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR019775 WD40_repeat_CS
     IPR001680 WD40_repeat
     IPR001632 Gprotein_B
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry Q13112

    ProtoNet protein and cluster: Q13112

    2 Blocks protein families:
    IPB001632 Beta G-protein (transducin) signature
    IPB001680 G-protein beta WD-40 repeat signature


    UniProtKB/Swiss-Prot: CAF1B_HUMAN, Q13112
    Similarity: Belongs to the WD repeat HIR1 family
    Similarity: Contains 7 WD repeats


    Function
    for CHAF1B gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: CAF1B_HUMAN, Q13112
    Function: Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone
    octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing
    newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor
    subsequent to DNA replication to complete the histone octamer. The CCR4-NOT complex functions as general transcription
    regulation complex

         Genatlas biochemistry entry for CHAF1B:
    chromatin assembly factor 1 subunit B,p60,histone chaperone assembling nucleosomes,on replicating DNA

    miRNA
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    hsa-miR-516b hsa-miR-34b
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    Inhib. RNA
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    Gene Editing
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    In Situ Assay
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    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003682chromatin binding TAS7600578
    GO:0005515protein binding IPI17452450
    GO:0042393histone binding NAS7600578
    GO:0051082unfolded protein binding TAS7600578


    CHAF1B for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for CHAF1B:
     Decreased G3BP1 protein expres  Wnt reporter upregulated 


    Pathways & Interactions
    for CHAF1B gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CHAF1B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/106 Interacting proteins for CHAF1B (Q131121, 2, 3 ENSP000003157004) via UniProtKB, MINT, STRING, and/or I2D (see all 106)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4BP628052, 3, ENSP000003665814MINT-7220359 I2D: score=2 STRING: ENSP00000366581
    HIST1H4CP628052, 3, ENSP000003670344MINT-7220359 I2D: score=2 STRING: ENSP00000367034
    HIST1H4DP628052, 3, ENSP000003432824MINT-7220359 I2D: score=2 STRING: ENSP00000343282
    HIST1H4EP628052, 3, ENSP000003536244MINT-7220359 I2D: score=2 STRING: ENSP00000353624
    HIST1H4HP628052, 3, ENSP000002893524MINT-7220359 I2D: score=2 STRING: ENSP00000289352
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006260DNA replication IEA--
    GO:0006281DNA repair IEA--
    GO:0006335DNA replication-dependent nucleosome assembly TAS7600578
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--


    CHAF1B for ontologies           About GeneDecksing



    Drugs & Compounds
    for CHAF1B gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CHAF1B
    Search CenterWatch for drugs/clinical trials and news about CHAF1B / CAF1B 

    Transcripts
    for CHAF1B gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for CHAF1B gene: 
    NM_005441.2  

    Unigene Cluster for CHAF1B:

    Chromatin assembly factor 1, subunit B (p60)
    Hs.75238  [show with all ESTs]
    Unigene Representative Sequence: NM_005441
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000314103(uc002yvj.3) ENST00000480486 ENST00000481458 ENST00000547793


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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHAF1B
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHAF1B

    Additional cDNA sequence: 

    AJ001856.1 AK092781.1 AK313152.1 BC001143.1 BC021218.2 U20980.1 X98262.1 

    6 DOTS entries:

    DT.114283  DT.99928033  DT.114282  DT.101957749  DT.95103371  DT.91760581 

    24/103 AceView cDNA sequences (see all 103):

    AK092781 CA489373 BC021218 BF509884 T16685 BX436477 NM_005441 BM808292 
    CR597529 U20980 BM477513 BG492144 BM550351 BC001143 CA454762 BP365327 
    AL554979 R39347 BP353233 BE792667 BX090123 BG390662 AL561489 BI256357 

    GeneLoc Exon Structure


    Expression
    for CHAF1B gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CHAF1B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    CHAF1B expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Neural TubeMesencephalic Ventricular ZoneNeural Tube
    Neural TubeMetencephalonNeural Tube
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See CHAF1B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CHAF1B

    SOURCE GeneReport for Unigene cluster: Hs.75238
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    In Situ
    Assay Products:     
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    Orthologs
    for CHAF1B gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CHAF1B gene from 9/31 species (see all 31)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves CHAF1B1 chromatin assembly factor 1, subunit B (p60) 74(n)
    77.24(a)    		   418514  NM_001008677.2  NP_001008677.2 
    lizard
    (Anolis carolinensis)    		 Reptilia CHAF1B6
    		 --
    		 71(a)
    		 1 ↔ 1
    		 3(141422424-141435525)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.77812 Xenopus laevis transcribed sequence with moderate similarity more 77.81(n)    BJ615996.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii Dr.35222 Danio rerio mRNA similar to chromatin assembly factor more 76.65(n)    BC045906.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Caf1-1051 , 3 chromatin assembly/disassembly
    histone-specific more3
    CG12892-PA1    		 39(a)3
    50.62(n)1
    43.64(a)1    		   47A93
    361071  NM_136745.41  NP_610589.21 
    worm
    (Caenorhabditis elegans)    		 Secernentea Y71G12B.1b3   -- 33(a)
    (best of 2)    		   I(1823455-1825906)   --
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes CAC2(YML102W)4
    CAC21    		 Component of the chromatin assembly complex (with Rlf2p more4
    Cac2p1    		 47.39(n)1
    38.07(a)1    		   13(68294-69700)4
    8548691, 4  NP_013605.11, 4 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons FAS21 transducin/WD40 domain-containing protein 51.36(n)
    42.73(a)    		   836584  NM_203262.2  NP_974991.1 
    rice
    (Oryza sativa)    		 Liliopsida Os08g01082001 hypothetical protein 47.4(n)
    38.46(a)    		   4344464  NM_001067339.1  NP_001060804.1 


    ENSEMBL Gene Tree for CHAF1B (if available)
    TreeFam Gene Tree for CHAF1B (if available) 

    Paralogs
    for CHAF1B gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CHAF1B gene

    CHAF1B for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for CHAF1B
    PGOHUM00000243727


    Genomic Variants
    for CHAF1B gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/577 NCBI SNPs in CHAF1B are shown (see all 577)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 21 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1807009141,2
    		--37755743(+) AATGCC/TTTGAG 1 -- us2k10--------
    rs9685991,2
    		H--37755760(-) GCTTCG/AAAAAA 1 -- us2k14Minor allele frequency- A:0.00NS EA 416
    rs1381493801,2
    		--37755775(+) TTAAG-/AGTT  
                AGTCC     		1 -- us2k10--------
    rs1864680721,2
    		--37755801(+) TTTCAC/TTATTA 1 -- us2k10--------
    rs1154131331,2
    		F,--37755919(+) AGTTAG/CAATTG 1 -- us2k11Minor allele frequency- C:0.09WA 118
    rs2186271,2
    		C,A,H,--37756035(-) CGGGAG/AGCGGG 1 -- us2k12Minor allele frequency- A:0.00NA 4
    rs1897170731,2
    		--37756060(+) TCTTGC/TCTCAG 1 -- us2k10--------
    rs1502070941,2
    		--37756191(+) TCCGCC/TCACCT 1 -- us2k10--------
    rs1816561661,2
    		--37756580(+) GAGACA/GCGAAG 1 -- us2k10--------
    rs1388015581,2
    		--37756675(+) CTGGAG/TATTCG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CHAF1B (37757676 - 37789125 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for CHAF1B
         1 CNV: 7322

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    Disorders / Diseases
    for CHAF1B gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    CHAF1B for disorders           About GeneDecksing

    OMIM gene information: 601245    OMIM disorders: --

    7 diseases for CHAF1B:    About MalaCards
    plague    werner syndrome    williams syndrome    down syndrome
    prostate cancer    prostatitis    melanoma


    Export disorders for CHAF1B gene to outside databases

    Publications
    for CHAF1B gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CHAF1B gene, integrated from 9 sources (see all 71):
    (articles sorted by number of sources associating them with CHAF1B)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication. (PubMed id 7600578)1, 2, 3 Kaufman P.D.... Stillman B. (1995)
    2. Nucleosome assembly activity and intracellular localization of human CAF-1 changes during the cell division cycle. (PubMed id 9614144)1, 2, 9 Marheineke K. and Krude T. (1998)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. BTG2 antiproliferative protein interacts with the human CCR4 complex existing in vivo in three cell-cycle-regulated forms. (PubMed id 12771185)1, 2 Morel A.-P.... Corbo L. (2003)
    6. CAF-1 and the inheritance of chromatin states: at the crossroads of DNA replication and repair. (PubMed id 10893180)1, 2 Ridgway P. and Almouzni G. (2000)
    7. The DNA sequence of human chromosome 21. (PubMed id 10830953)1, 2 Hattori M....Yaspo M.L. (2000)
    8. Recruitment of phosphorylated chromatin assembly factor 1 to chromatin after UV irradiation of human cells. (PubMed id 9813080)1, 2 Martini E.... Almouzni G. (1998)
    9. The gene encoding the p60 subunit of chromatin assemb ly factor I (CAF1P60) maps to human chromosome 21q22.2, a region associated wit h some of the major features of Down syndrome. (PubMed id 8792829)1, 3 Katsanis N. and Fisher E.M. (1996)
    10. Identification of novel M phase phosphoproteins by expression cloning. (PubMed id 8885239)1, 2 Matsumoto-Taniura N....Westendorf J.M. (1996)

    External Searches for CHAF1B gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    Genome Databases showing CHAF1B gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8208 HGNC: 1911 AceView: CHAF1B Ensembl:ENSG00000159259 euGenes: HUgn8208
    ECgene: CHAF1B H-InvDB: CHAF1B

    Other Databases showing CHAF1B gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing CHAF1B gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CHAF1B Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for CHAF1B Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for CHAF1B gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for CHAF1B gene:
    Search GeneIP for patents involving CHAF1B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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