CHAF1A Gene
protein-coding GIFtS: 55
GCID: GC19P004353
|
|
chromatin assembly factor 1, subunit A (p150)
| |
Aliases
for CHAF1A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromatin Assembly Factor 1, Subunit A (P150)1 2 | | CAF-I 150 KDa Subunit2 3 | | CAF1P1501 2 3 | | CAF-I P1502 3 | | CAF-11 2 | | Hp1501 | | CAF11 2 | | MGC712291 | | CAF1B1 2 | | Chromatin Assembly Factor 1 Subunit A2 | | P1501 2 | | Chromatin Assembly Factor I (150 KDa)2 | | Chromatin Assembly Factor I P150 Subunit2 3 | | CAF3 | | CAF-1 Subunit A2 3 | | |
Export aliases for CHAF1A gene to outside databasesPrevious GC identifers: GC19P004494 GC19P004342 GC19P004165 |
Summaries
for CHAF1A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CHAF1A:
Chromatin assembly factor I (CAF1) is a nuclear complex consisting of p50, p60 (CHAF1B; MIM 601245), and p150 (CHAF1A)subunits that assembles histone octamers onto replicating DNA in vitro (Kaufman et al., 1995 (PubMed7600578)).(supplied by OMIM, Mar 2008)
UniProtKB/Swiss-Prot: CAF1A_HUMAN, Q13111Function: Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication andDNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosomeassembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to thischromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4.It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins toheterochromatic DNA replication foci (By similarity). The CCR4-NOT complex functions as general transcriptionregulation complex. Also involved in vitamin D-coupled transcription regulation via its association with the WINACcomplex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-boundVDR-mediated transrepression of the CYP27B1 gene
Gene Wiki entry for CHAF1A
|
Genomic Views
for CHAF1A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011255.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CHAF1A gene promoter:
c-Fos AP-1 AML1a
Other transcription factors
Search SABiosciences Chromatin IP Primers for CHAF1A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHAF1A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.3 Ensembl cytogenetic band: 19p13.3 HGNC cytogenetic band: 19p13.3CHAF1A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P004353: view genomic region
(about GC identifiers)
Start:
|
4,402,659 bp from pter |
End:
|
4,445,015 bp from pter |
Size:
|
42,357 bases |
Orientation:
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plus strand |
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Proteins
for CHAF1A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CAF1A_HUMAN, Q13111 (See
protein sequence)Recommended Name: Chromatin assembly factor 1 subunit A Size: 956 amino acids; 106926 Da
Subunit: Homodimer. Part of the CAF-1 complex that contains RBBP4, CHAF1B and CHAF1A. CHAF1A binds directly to CHAF1B.Only minor amounts of RBBP4 are complexed with CHAF1A and CHAF1B in G1 phase. Part of the CCR4-NOT core complex thatcontains CHAF1A, CHAF1B, CNOT1, CNOT2, CNOT3, CNOT4, CNOT6 and CNOT8. CHAF1A binds directly to PCNA and to CBX1. BindsMBD1. Interacts directly with CBX5 via the PxVxL motif. During DNA replication, it forms a S phase-specific complexthat facilitates DNA methylation and histone H3 'Lys-9' methylation during replication-coupled chromatin assembly andis at least composed of the CHAF1A, MBD1 and SETDB1. Component of the WINAC complex, at least composed of SMARCA2,SMARCA4, SMARCB1, SMARCC1, SMARCC2, SMARCD1, SMARCE1, ACTL6A, BAZ1B/WSTF, ARID1A, SUPT16H, CHAF1A and TOP2B. Interactswith CBX5
Subcellular location: Nucleus. Note=DNA replication foci
Developmental stage: Active complex is found in G1, S and G2 phases
Sequence caution: Sequence=AAA76736.1; Type=Erroneous initiation; Sequence=AAF04291.1; Type=Erroneous initiation;Sequence=AAH52620.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=AAH52620.1;Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence starting in position 426;
Secondary accessions: Q6NXG5 Q7Z7K3 Q9UJY8Alternative splicing: 3 isoforms: Q13111-1 Q13111-2 Q13111-3 Explore the universe of human proteins at neXtProt for CHAF1A: NX_Q13111
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q13111
CHAF1A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_005474.2
ENSEMBL proteins: ENSP00000301280 ENSP00000465142 ENSP00000467296 ENSP00000466888 ENSP00000466475
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
CHAF1A for ontologies About GeneDecksing
CHAF1A Antibody Products:
Assay Products for CHAF1A: |
Protein
Domains /
Families
for CHAF1A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CHAF1A for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q13111ProtoNet protein and cluster: Q13111 UniProtKB/Swiss-Prot: CAF1A_HUMAN, Q13111Domain: Contains one Pro-Xaa-Val-Xaa-Leu (PxVxL) motif, which is required for interaction with chromoshadow domains.This motif requires additional residues -7, -6, +4 and +5 of the central Val which contact the chromoshadow domainSimilarity: Belongs to the CHAF1A family |
Function
for CHAF1A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CAF1A_HUMAN, Q13111Function: Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication andDNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosomeassembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to thischromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4.It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins toheterochromatic DNA replication foci (By similarity). The CCR4-NOT complex functions as general transcriptionregulation complex. Also involved in vitamin D-coupled transcription regulation via its association with the WINACcomplex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-boundVDR-mediated transrepression of the CYP27B1 gene
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHAF1A (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHAF1A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CHAF1A (NM_005483) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CHAF1A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHAF1A |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHAF1A |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
CHAF1A for ontologies About GeneDecksing
6 GenomeRNAi human phenotypes for CHAF1A:
Animal Models:
Mouse knock-out Chaf1atm1Ger for CHAF1A
3 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Chaf1a):
CHAF1A for phenotypes About GeneDecksing
|
Pathways & Interactions
for CHAF1A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Chromatin Regulation / Acetylation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Cell Signaling Technology (CST) Pathway for CHAF1A
CHAF1A for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CHAF1A
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/136 Interacting proteins for CHAF1A (Q131111, 2, 3 ENSP000003012804) via UniProtKB, MINT, STRING, and/or I2D (see all 136)About this table
Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table
CHAF1A for ontologies About GeneDecksing
|
Drugs & Compounds
for CHAF1A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CHAF1A
Search CenterWatch for drugs/clinical trials and news about CHAF1A / CAF1A
|
Transcripts
for CHAF1A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CHAF1A gene: NM_005483.2 Unigene Cluster for CHAF1A: Chromatin assembly factor 1, subunit A (p150) Hs.79018 [show with all ESTs]Unigene Representative Sequence: NM_0054837 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000301280(uc002mal.3) ENST00000587580 ENST00000585854 ENST00000587739
ENST00000585371 ENST00000587368 ENST00000589648
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHAF1A (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHAF1A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CHAF1A (NM_005483) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CHAF1A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHAF1A |
Additional cDNA sequence: BC005813.2 BC011560.1 BC041606.1 BC052620.1 BC067093.1 U20979.1 11 DOTS entries: DT.451772 DT.75189320 DT.434268 DT.121498113 DT.100780596 DT.75189324 DT.100780601 DT.86855262 DT.92429446 DT.92429450 DT.95198998 24/238 AceView cDNA sequences (see all 238): BU957042 BC011560 AI494528 BQ052743 NM_005483 BC052620 BQ649149 BU165501 AW015784 BQ651348 AI217058 BQ652141 BM971109 CA489290 BM824075 BM917102 BC005813 AA033880 BE513903 BM676380 BM465304 BU931789 AA158034 BE504627
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for CHAF1A About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | · | 3c | · | 3d | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | ^ | 15 |
|---|
|
| SP1: | | | | | | | - | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | - | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CHAF1A
|
Expression
for CHAF1A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CHAF1A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See CHAF1A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CHAF1A
SOURCE GeneReport for Unigene cluster: Hs.79018
SABiosciences Custom PCR Arrays for CHAF1A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHAF1A
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CHAF1A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHAF1A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHAF1A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHAF1A |
Orthologs
for CHAF1A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CHAF1A gene from 9/28 species (see all 28) About this table
ENSEMBL Gene Tree for CHAF1A (if available)
TreeFam Gene Tree for CHAF1A (if available) |
Paralogs
for CHAF1A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CHAF1A gene
CHAF1A for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for CHAF1A
PGOHUM00000236323
|
Genomic Variants
for CHAF1A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CHAF1A (4402659 - 4445015 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CHAF1A: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHAF1A |
|
Disorders
/ Diseases
for CHAF1A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CHAF1A for disorders About GeneDecksing
OMIM gene information: 601246
OMIM disorders: --
13  diseases for CHAF1A: About MalaCardscornelia de lange syndrome tuberous sclerosis digeorge syndrome bloom syndrome
werner syndrome williams syndrome squamous cell carcinoma down syndrome
meningioma prostate cancer glioblastoma prostatitis
carcinoma
1 disease from the University of Copenhagen DISEASES database for CHAF1A:Cornelia de Lange syndrome Human Genome Epidemiology (HuGE) Navigator: CHAF1A (4 documents)
Export disorders for CHAF1A gene to outside databases
|
Publications
for CHAF1A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CHAF1A gene, integrated from 9 sources (see all 116):
(articles sorted by number of sources associating them with CHAF1A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication. (PubMed id 7600578)1, 2, 3, 9 Kaufman P.D.... Stillman B. (1995)
- Dimerization of the largest subunit of chromatin assembly factor 1: importance in vitro and during Xenopus early development. (PubMed id 11296234)1, 2, 9 Quivy J.-P.... Almouzni G. (2001)
- Genomic sequence and expression analyses of human chromatin assembly factor 1 p150 gene. (PubMed id 11250073)1, 2, 9 Dong H.... Huang G.M. (2001)
- CAF-1 and the inheritance of chromatin states: at the crossroads of DNA replication and repair. (PubMed id 10893180)1, 2, 9 Ridgway P. and Almouzni G. (2000)
- Replication-dependent marking of DNA by PCNA facilitates CAF-1- coupled inheritance of chromatin. (PubMed id 10052459)1, 2, 9 Shibahara K. and Stillman B. (1999)
- A CAF-1-PCNA-mediated chromatin assembly pathway triggered by sensing DNA damage. (PubMed id 10648606)1, 2, 9 Moggs J.G.... Almouzni G. (2000)
- Human POGZ modulates dissociation of HP1alpha from mi totic chromosome arms through Aurora B activation. (PubMed id 20562864)1, 2 Nozawa R.S....Obuse C. (2010)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain. (PubMed id 15882967)1, 2 Lechner M.S.... Rauscher F.J. III (2005)
- Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly. (PubMed id 15327775)1, 2 Sarraf S.A. and Stancheva I. (2004)
|
External Searches for CHAF1A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CHAF1A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CHAF1A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CHAF1A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for CHAF1A gene:
Search GeneIP for patents involving CHAF1A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CHAF1A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for CHAF1A | | OriGene shRNA RFP for CHAF1A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CHAF1A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CHAF1A | | | OriGene Protein Over-expression Lysate for CHAF1A | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CHAF1A | | OriGene 3'-UTR Clone for CHAF1A | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CHAF1A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CHAF1A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for CHAF1A | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CHAF1A | | OriGene Custom Protein Services for CHAF1A | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CHAF1A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHAF1A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHAF1A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CHAF1A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHAF1A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHAF1A |
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| | Antibodies & Assays for CHAF1A (CAF-1A) |
| | | | Search Tocris compounds for CHAF1A |
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 | | | CHAF1A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHAF1A |
|  |  |  | | | | ThermoFisher Antibodies for CHAF1A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CHAF1A |
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