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CHADL Gene

protein-coding   GIFtS: 45
GCID: GC22M041625

Chondroadherin-Like

  Search for CHADL
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
chondroadherin-like1 2
SLRR4B2 3
Chondroadherin-Like Protein2

External Ids:    HGNC: 251651   Entrez Gene: 1503562   Ensembl: ENSG000001003997   UniProtKB: Q6NUI63   
ORGUL members:         

Export aliases for CHADL gene to outside databases

Previous GC identifers: GC22U900391 GC22M039955 GC22M024589


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CHADL Gene:
CHADL (chondroadherin-like) is a protein-coding gene. An important paralog of this gene is GP5.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000022.10  NT_011520.13  NC_018933.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CHADL gene promoter:
         Pax-5   Brachyury   Olf-1   AP-4   LCR-F1   C/EBPalpha   E47   CREB   Max   c-Myc   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for CHADL

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CHADL


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.2   Ensembl cytogenetic band:  22q13.2   HGNC cytogenetic band: 22q13.2

CHADL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CHADL gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22M041625:  view genomic region     (about GC identifiers)

Start:
41,625,514 bp from pter      End:
41,636,938 bp from pter
Size:
11,425 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CHADL_HUMAN, Q6NUI6 (See protein sequence)
Recommended Name: Chondroadherin-like protein precursor  
Size: 762 amino acids; 82388 Da
Sequence caution: Sequence=AAH19839.1; Type=Frameshift; Positions=504; Sequence=AAH68590.1; Type=Erroneous
initiation;
Secondary accessions: Q05CY2 Q4G0S0 Q5JY13 Q86XY1 Q96E60
Alternative splicing: 2 isoforms:  Q6NUI6-1   Q6NUI6-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CHADL: NX_Q6NUI6

Explore proteomics data for CHADL at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn52, Asn626
  • Modification sites at PhosphoSitePlus

  • See CHADL Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_612490.1  
    ENSEMBL proteins: 
     ENSP00000392046   ENSP00000216241   ENSP00000412359  

    CHADL Human Recombinant Protein Products:

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    Browse OriGene Protein Over-expression Lysates
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    OriGene Custom Protein Services for CHADL
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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CHADL

     
    Search eBioscience for Proteins for CHADL 

    CHADL Antibody Products:

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    Novus Biologicals CHADL Antibodies
    Abcam antibodies for CHADL
    Cloud-Clone Corp. Antibodies for CHADL
    Search ThermoFisher Antibodies for CHADL
    LSBio Antibodies in human, mouse, rat for CHADL

    CHADL Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CHADL
    Cloud-Clone Corp. CLIAs for CHADL
    Search eBioscience for ELISAs for CHADL 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR000483 Cys-rich_flank_reg_C
     IPR001611 Leu-rich_rpt
     IPR003591 Leu-rich_rpt_typical-subtyp
     IPR000372 LRR-contain_N

    Graphical View of Domain Structure for InterPro Entry Q6NUI6

    ProtoNet protein and cluster: Q6NUI6

    3 Blocks protein domains:
    IPB000372 Cysteine-rich flanking region
    IPB000483 Cysteine-rich flanking region
    IPB001611 Leucine-rich repeat signature


    UniProtKB/Swiss-Prot: CHADL_HUMAN, Q6NUI6
    Similarity: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class IV subfamily
    Similarity: Contains 19 LRR (leucine-rich) repeats
    Similarity: Contains 2 LRRCT domains
    Similarity: Contains 2 LRRNT domains


    Find genes that share domains with CHADL           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with CHADL           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CHADL
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CHADL

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CHADL
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CHADL

    miRNA
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    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CHADL

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector: CHADL (NM_138481)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CHADL
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CHADL

    Cell Line
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHADL


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CHADL_HUMAN, Q6NUI6: Secreted, extracellular space, extracellular matrix (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular2
    mitochondrion2
    golgi apparatus1
    lysosome1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005578proteinaceous extracellular matrix IEA--
    GO:0031012colocalizes with extracellular matrix ISS--

    Find genes that share ontologies with CHADL           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CHADL
    Interactions:

        Search GeneGlobe Interaction Network for CHADL

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for CHADL (ENSP000002162414) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GP1BAENSP000003293804STRING: ENSP00000329380
    VWFENSP000002614054STRING: ENSP00000261405
    CAB39ENSP000002584184STRING: ENSP00000258418
    CAB39LENSP000002616694STRING: ENSP00000261669
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CHADL



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CHADL gene: 
    NM_138481.1  

    Unigene Cluster for CHADL:

    Chondroadherin-like
    Hs.344488  [show with all ESTs]
    Unigene Representative Sequence: BC068590
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000417999 ENST00000216241(uc003azq.4 uc010gyj.3) ENST00000455425

    miRNA
    Products:
         
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    Search for qRT-PCR Assays for microRNAs that regulate CHADL
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CHADL
    Predesigned siRNA for gene silencing in human, mouse, rat CHADL
    Clone
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    OriGene clones in human, mouse for CHADL (see all 6)
    OriGene ORF clones in mouse, rat for CHADL
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CHADL (NM_138481)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CHADL
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CHADL
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for CHADL
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CHADL
      QuantiTect SYBR Green Assays in human, mouse, rat CHADL
      QuantiFast Probe-based Assays in human, mouse, rat CHADL

    Additional mRNA sequence: 

    BC012882.1 BC019839.1 BC040188.1 BC048421.1 BC068590.1 

    3 DOTS entries:

    DT.91659395  DT.120647809  DT.40115125 

    Selected AceView cDNA sequences (see all 323):

    BM551464 CR456557 BQ061240 BU194287 H55068 BQ000147 BU182483 BC068590 
    BQ053784 BU191873 BQ431293 BU163000 BM542955 AI648516 BQ893444 BQ424384 
    BQ060789 BU617884 BQ641923 CR595421 BM911800 BM694126 BC004990 BQ710884 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for CHADL    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b
    SP1:                    -     -     -                           
    SP2:              -                                             
    SP3:                                                            


    ECgene alternative splicing isoforms for CHADL

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CHADL expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCTTCCAGG
    CHADL Expression
    About this image


    CHADL expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebral Cortex
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Ovary (Reproductive System)
             Oviduct
     
     Pancreas (Endocrine System)
             Islets of Langerhans
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    CHADL Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CHADL Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.344488
        Custom PCR Arrays for CHADL
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHADL

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for CHADL gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Chadl1 , 5 chondroadherin-like1, 5 83.82(n)1
    82.29(a)1
      15 (38.20 cM)5
    2146851  NM_001164320.11  NP_001157792.11 
     816782965 
    chicken
    (Gallus gallus)
    Aves CHADL1 chondroadherin-like 63.66(n)
    54.65(a)
      417998  NM_001252276.1  NP_001239205.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    19(a)
    many ↔ many
    5(26264605-26274161)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia chadl1 chondroadherin-like 52.3(n)
    48.99(a)
      100491048  XM_002934737.2  XP_002934783.1 
    zebrafish
    (Danio rerio)
    Actinopterygii chadlb1 chondroadherin-like b 54.81(n)
    49.36(a)
      100330176  XM_002663946.2  XP_002663992.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta haf6
    hattifattener
    9(a)
    1 → many
    2L(1555130-1608404)


    ENSEMBL Gene Tree for CHADL (if available)
    TreeFam Gene Tree for CHADL (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CHADL gene
    GP52  CPN22  LRIG32  LRRTM42  CHAD2  LRRC152  LRIG22  LRRTM32  
    IGFALS2  LRIG12  LRRTM22  LRRTM12  LRG12  
    3 SIMAP similar genes for CHADL using alignment to 3 protein entries:     CHADL_HUMAN (see all proteins):
    CHAD    ISLR    SLIT2

    Find genes that share paralogs with CHADL           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CHADL (see all 208)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs96115221,2
    C,F,A,H--41627924(+) AGCCCC/TTACCC 1 -- int112Minor allele frequency- T:0.15NS EA NA WA 918
    rs81351391,2
    C,F,A--41628029(+) TAGTCG/ATTTGG 1 -- int16Minor allele frequency- A:0.05NA WA CSA 264
    rs1478397921,2
    --41628047(+) AATTTA/TCACCT 1 -- int10--------
    rs1891169461,2
    --41628063(+) CGGGCA/GCGGTG 1 -- int10--------
    rs1394871,2
    F--41628064(+) gggcgC/Tggtgg 1 -- int10--------
    rs1414809301,2
    C--41628065(+) GGCGCA/GGTGGC 1 -- int10--------
    rs1844383921,2
    C--41628074(+) GCTCAC/TGCCTG 1 -- int10--------
    rs1502971791,2
    --41628079(+) CGCCTA/GTAATC 1 -- int10--------
    rs1119072081,2
    C,F--41628107(+) CACGGC/TGGGCG 1 -- int11Minor allele frequency- T:0.50WA 2
    rs72931371,2
    C,F,A,H--41628119(+) ATCACG/AAGGTC 1 -- int15Minor allele frequency- A:0.40NA WA 10

    HapMap Linkage Disequilibrium report for CHADL (41625514 - 41636938 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for CHADL:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv915118CNV Loss21882294
    nsv915117CNV Loss21882294
    nsv915119CNV Loss21882294
    nsv915116CNV Loss21882294
    nsv524585CNV Loss19592680
    nsv459888CNV Gain19166990

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CHADL
    DNA2.0 Custom Variant and Variant Library Synthesis for CHADL

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with CHADL           About GenesLikeMe

    Genetic Association Database (GAD): CHADL

    Export disorders for CHADL gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CHADL gene integrated from 10 sources:
    (articles sorted by number of sources associating them with CHADL)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    2. Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication. (PubMed id 18854154)1 KAPnig R....Chanda S.K. (Cell 2008)
    3. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. The DNA sequence of human chromosome 22. (PubMed id 10591208)2 Dunham I.... Wright H. (Nature 1999)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 150356 HGNC: 25165 AceView: RANGAP1 Ensembl:ENSG00000100399 euGenes: HUgn150356
    ECgene: CHADL H-InvDB: CHADL

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CHADL Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CHADL gene:
    Search GeneIP for patents involving CHADL

    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for CHADL  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
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     OriGene Custom Antibody Services for CHADL   OriGene Custom Protein Services for CHADL  

     
     
     Block miRNA regulation of human, mouse, rat CHADL using miScript Target Protectors SeqTarget long-range PCR primers for resequencing CHADL
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CHADL Predesigned siRNA for gene silencing in human, mouse, rat CHADL
     QuantiFast Probe-based Assays in human, mouse, rat CHADL QuantiTect SYBR Green Assays in human, mouse, rat CHADL
     Custom PCR Arrays for CHADL Search Chromatin IP Primers for CHADL
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CHADL  Search GeneGlobe Interaction Network for CHADL
     Regulatory tfbs in CHADL promoter
     GenScript Custom Purified and Recombinant Proteins Services for CHADL GenScript cDNA clones with any tag delivered in your preferred vector for CHADL
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     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
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     Search Tocris compounds for CHADL
     Browse Sino Biological Proteins
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     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
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     Proteins for CHADL
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     Browse ESI BIO Cell Lines and PureStem Progenitors for CHADL
     Gene Synthesis
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     Browse SwitchGear 3'UTR luciferase reporter plasmids for CHADL
     Browse SwitchGear Promoter luciferase reporter plasmids for CHADL
     Search ThermoFisher Antibodies for CHADL
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CHADL
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CHADL
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CHADL
     LSBio Antibodies in human, mouse, rat for CHADL
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     Browse compounds at ApexBio
     Search Addgene for plasmids for CHADL
      Search eBioscience for proteins for CHADL
      Search eBioscience for elisas for CHADL
      eBioscience FlowRNA Probe Sets
           
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