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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CHAD Gene

protein-coding   GIFtS: 55
GCID: GC17M048541

Chondroadherin

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
chondroadherin1 2
Chondroadherin Proteoglycan1 2
Cartilage Leucine-Rich Protein2 3
SLRR4A2 3

External Ids:    HGNC: 19091   Entrez Gene: 11012   Ensembl: ENSG000001364577   OMIM: 6021785   UniProtKB: O153353   

Export aliases for CHAD gene to outside databases

Previous GC identifers: GC17M048254 GC17M051023 GC17M048883 GC17M049016 GC17M045896 GC17M043909


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CHAD Gene:
Chondroadherin is a cartilage matrix protein thought to mediate adhesion of isolated chondrocytes. The protein
contains 11 leucine-rich repeats flanked by cysteine-rich regions. The chondroadherin messenger RNA is present in
chondrocytes at all ages. (provided by RefSeq, Jul 2008)

GeneCards Summary for CHAD Gene: 
CHAD (chondroadherin) is a protein-coding gene. Diseases associated with CHAD include autoimmune hemolytic anemia, and hemolytic anemia, and among its related super-pathways are Focal Adhesion and Non-integrin membrane-ECM interactions. GO annotations related to this gene include extracellular matrix structural constituent. An important paralog of this gene is GP5.

UniProtKB/Swiss-Prot: CHAD_HUMAN, O15335
Function: Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least
for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important role in the regulation
of chondrocyte growth and proliferation (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NT_010783.15  NC_018928.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CHAD gene promoter:
         NF-1/L   NF-1   p53   Brachyury   Pax-2   Pax-2a   HNF-4alpha2   HNF-4alpha1   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCHAD promoter sequence
   Search SABiosciences Chromatin IP Primers for CHAD

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHAD


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.33   Ensembl cytogenetic band:  17q21.33   HGNC cytogenetic band: 17q21.33

CHAD Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CHAD gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M048541:  view genomic region     (about GC identifiers)

Start:
48,541,853 bp from pter      End:
48,546,327 bp from pter
Size:
4,475 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CHAD_HUMAN, O15335 (See protein sequence)
Recommended Name: Chondroadherin precursor  
Size: 359 amino acids; 40476 Da
Subunit: Mostly monomeric (By similarity). Interacts with collagen type II
Subcellular location: Secreted, extracellular space, extracellular matrix (By similarity)
Secondary accessions: A8K812 Q6GTU0 Q96RJ5

Explore the universe of human proteins at neXtProt for CHAD: NX_O15335

Explore proteomics data for CHAD at MOPED 

CHAD Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

CHAD Protein Expression

REFSEQ proteins: NP_001258.2  
ENSEMBL proteins: 
 ENSP00000425672   ENSP00000423812   ENSP00000258969  

Human Recombinant Protein Products for CHAD: 
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Cloud-Clone Corp. Proteins for CHAD 

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005578proteinaceous extracellular matrix TAS--

CHAD for ontologies           About GeneDecksing



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EMD Millipore Mono- and Polyclonal Antibodies for the study of CHAD
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Cloud-Clone Corp. CLIAs for CHAD


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
HGNC Gene Families: 
SLRR: Proteoglycans / Extracellular Matrix : Small leucine-rich repeats

4 InterPro protein domains:
 IPR000483 Cys-rich_flank_reg_C
 IPR001611 Leu-rich_rpt
 IPR003591 Leu-rich_rpt_typical-subtyp
 IPR000372 LRR-contain_N

Graphical View of Domain Structure for InterPro Entry O15335

ProtoNet protein and cluster: O15335

2 Blocks protein domains:
IPB000372 Cysteine-rich flanking region
IPB000483 Cysteine-rich flanking region


UniProtKB/Swiss-Prot: CHAD_HUMAN, O15335
Similarity: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class IV subfamily
Similarity: Contains 9 LRR (leucine-rich) repeats
Similarity: Contains 1 LRRCT domain
Similarity: Contains 1 LRRNT domain


CHAD for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: CHAD_HUMAN, O15335
Function: Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least
for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important role in the regulation
of chondrocyte growth and proliferation (By similarity)

     Genatlas biochemistry entry for CHAD:
chondroadherin,36kDa,expressed in chodrocytes,leucine-rich repeat (LRR) family

     Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005201extracellular matrix structural constituent NAS--
GO:0005515protein binding ----
     
CHAD for ontologies           About GeneDecksing


Animal Models:
   inGenious Targeting Laboratory - Custom generated mouse model solutions for CHAD 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CHAD

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CHAD 
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CHAD 

miRNA
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hsa-miR-1226 hsa-miR-185* hsa-miR-222* hsa-miR-571 hsa-miR-199b-3p hsa-miR-199a-3p hsa-miR-3129-5p hsa-miR-545
SwitchGear 3'UTR luciferase reporter plasmidCHAD 3' UTR sequence
Inhib. RNA
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Cell Line
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHAD


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for CHAD About                                                                                                See pathways by source

SuperPathContained pathways About
1Focal Adhesion
Focal Adhesion0.64
Focal adhesion0.64
2Non-integrin membrane-ECM interactions
ECM-receptor interaction0.42
3PI3K-Akt signaling pathway
PI3K-Akt signaling pathway

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways


1 BioSystems Pathway for CHAD
    Focal Adhesion



3         Kegg Pathways  (Kegg details for CHAD):
    PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction


CHAD for pathways           About GeneDecksing

Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CHAD

STRING Interaction Network Preview (showing 5 interactants - click image to see 21)

5/21 Interacting proteins for CHAD (O153353 ENSP000002589694) via UniProtKB, MINT, STRING, and/or I2D (see all 21)
InteractantInteraction Details
GeneCardExternal ID(s)
COL2A1P024583, ENSP000003698894I2D: score=1 STRING: ENSP00000369889
ITGA1ENSP000002825884STRING: ENSP00000282588
ITGA10ENSP000003583104STRING: ENSP00000358310
ITGA11ENSP000003272904STRING: ENSP00000327290
ITGA2ENSP000002965854STRING: ENSP00000296585
About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0001502cartilage condensation IEA--
GO:0001558regulation of cell growth NAS--

CHAD for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

CHAD for compounds           About GeneDecksing

Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CHAD

2 Novoseek inferred chemical compound relationships for CHAD gene    About this table
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
glycosaminoglycan 40.6 1 12354766 (1)
leucine 36.5 3 15332017 (1), 17093390 (1)

Search CenterWatch for drugs/clinical trials and news about CHAD

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CHAD gene: 
NM_001267.2  

Unigene Cluster for CHAD:

Chondroadherin
Hs.97220  [show with all ESTs]
Unigene Representative Sequence: AK292177
3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000506187 ENST00000508540(uc010dbr.3) ENST00000258969(uc010dbs.3)

miRNA
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hsa-miR-1226 hsa-miR-185* hsa-miR-222* hsa-miR-571 hsa-miR-199b-3p hsa-miR-199a-3p hsa-miR-3129-5p hsa-miR-545
SwitchGear 3'UTR luciferase reporter plasmidCHAD 3' UTR sequence
Inhib. RNA
Products:
     
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                     Customized lentivirus expression plasmids for stable overexpression of CHAD 
Primer
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  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHAD
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHAD

Additional mRNA sequence: 

AF371328.1 AK292177.1 BC036360.1 BC073974.1 

6 DOTS entries:

DT.97765516  DT.100746839  DT.121003356  DT.315196  DT.97842206  DT.91832185 

24/65 AceView cDNA sequences (see all 65):

CD611066 CA419191 CA418441 CA412761 BQ181527 BC036360 BQ006680 BQ771633 
BI519995 BU617686 CA428195 BQ029011 BQ006783 CD611069 BM988025 CN480369 
BQ447743 CD611071 BE218409 BQ447819 BF196113 BQ044947 BQ182753 AF371328 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CHAD expression in normal human tissues (normalized intensities)      CHAD embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: CTGCAATTTC
CHAD Expression
About this image


CHAD expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database 
 5/8 selected tissues (see all 8) fully expand
 
 Bone (Muscoskeletal System)    fully expand to see all 18 entries
         Osteochondro Mesenchymal Cells Sacral Vertebrae
         Zeugopod Long Bone
         HyStem+TGFbeta3+GDF5-induced SK11 cells
         skeleton/pectoral girdle and thoracic body wall/scapula   
 
 Cartilage (Muscoskeletal System)    fully expand to see all 16 entries
         Mesenchymal Condensate Cells Zeugopod
         Meckel's Cartilage
         HyStem+TGFbeta3+GDF5-induced SK11 cells
         sensory organ/nose/nasal septum   
 
 Lung (Respiratory System)    fully expand to see all 3 entries
         bronchus   
 
 Neural Crest (Gastrulation Derivatives)
         skeleton/cranium/viscerocranium   
 
 Nose (Sensory Organs)
         sensory organ/nose/nasal septum   

See CHAD Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CHAD

SOURCE GeneReport for Unigene cluster: Hs.97220

UniProtKB/Swiss-Prot: CHAD_HUMAN, O15335
Tissue specificity: Present in chondrocytes at all ages

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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHAD

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for CHAD gene from 6/11 species (see all 11)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Chad1 , 5 chondroadherin1, 5 86.63(n)1
93.79(a)1
  11 (58.90 cM)5
126431  NM_007689.41  NP_031715.11 
 945650475 
chicken
(Gallus gallus)
Aves CHAD1 chondroadherin 71.14(n)
66.57(a)
  769665  XM_001232035.2  XP_001232036.1 
lizard
(Anolis carolinensis)
Reptilia CHAD6
--
--
71(a)
17(a)
1 ↔ 1
possible ortholog
2(116276713-116290960)
5(26264605-26274161)
zebrafish
(Danio rerio)
Actinopterygii chad1 chondroadherin 64.48(n)
62.5(a)
  394038  NM_201063.1  NP_957357.1 
fruit fly
(Drosophila melanogaster)
Insecta Tollo6
Toll-66
(see all 5)
Toll-6
(see all 5)
6(a)
5(a)
(see all 5)
possible ortholog
possible ortholog
(see all 5)
3L(15228719-15235932)
3L(15329792-15337417)
worm
(Caenorhabditis elegans)
Secernentea tol-16
lron-156
(see all 7)
Protein LRON-15
(see all 7)
7(a)
7(a)
(see all 7)
possible ortholog
possible ortholog
(see all 7)
I(443999-461607)
II(6540217-6544892)


ENSEMBL Gene Tree for CHAD (if available)
TreeFam Gene Tree for CHAD (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for CHAD gene
GP52  CPN22  LRRC152  LRRTM32  IGFALS2  LRIG12  LRRTM22  RTN4R2  
LRRTM12  LRG12  NYX2  LRIG32  LRRTM42  LRIG22  CHADL2  RTN4RL12  
LRRC702  RTN4RL22  
5 SIMAP similar genes for CHAD using alignment to 2 protein entries:     CHAD_HUMAN (see all proteins):
CHADL    LRRTM4    LRRTM2    LRRC4C    NGL1

CHAD for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

3 SNPs in CHAD are shown    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 17 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
VAR_0520194
----see VAR_0520192 R Q mis40--------
VAR_0306314
----see VAR_0306312 T I mis40--------
rs1470474481,2
C--48543624(+) TTGTA-/TATTTT 1 -- int10--------

HapMap Linkage Disequilibrium report for CHAD (48541853 - 48546327 bp)

Structural Variations
     Database of Genomic Variants (DGV) 4 variations for CHAD:    About this table     
Variant IDTypeSubtypePubMed ID
nsv833476CNV Loss17160897
nsv2081CNV Loss18451855
dgv3228n71CNV Gain21882294
nsv908600CNV Gain21882294

SABiosciences Cancer Mutation PCR Assays
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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 602178    OMIM disorders: --

6 diseases for CHAD:    About MalaCards
autoimmune hemolytic anemia    hemolytic anemia    anemia    osteoarthritis
rheumatoid arthritis    arthritis


CHAD for disorders           About GeneDecksing


Export disorders for CHAD gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for CHAD gene, integrated from 9 sources (see all 27):
(articles sorted by number of sources associating them with CHAD)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The structure and chromosome location of the human chondroadherin gene (CHAD). (PubMed id 9344663)1, 2, 3, 9 Grover J.... Roughley P.J. (1997)
  2. Association of chondroadherin with collagen type II. (PubMed id 11445564)1, 2, 9 Maansson B.... Heinegaard D. (2001)
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  4. Variation in chondroadherin abundance and fragmentati on in the human scoliotic disc. (PubMed id 19525844)1, 9 Haglund L....Roughley P. (2009)
  5. Integrin alpha2beta1 is a receptor for the cartilage matrix protein chondroadherin. (PubMed id 9281592)1, 9 Camper L....Lundgren-Akerlund E. (1997)
  6. The C-terminal peptide of chondroadherin modulates cel lular activity by selectively binding to heparan sulfate chains. (PubMed id 23172228)1 Haglund L....Heinegard D. (2013)
  7. Identification and characterization of the integrin a lpha2beta1 binding motif in chondroadherin mediating cell attachment. (PubMed id 21127050)1 Haglund L....HeinegAYrd D. (2011)
  8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
  9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
  10. Cartilage matrix proteins. A basic 36-kDa protein with a restricted distribution to cartilage and bone. (PubMed id 1939097)1 Larsson T....Heinegard D. (1991)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 1101 HGNC: 1909 AceView: CHAD Ensembl:ENSG00000136457 euGenes: HUgn1101
ECgene: CHAD Kegg: 1101 H-InvDB: CHAD

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for CHAD Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for CHAD gene:
Search GeneIP for patents involving CHAD

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 Proteins for CHAD
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GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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