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CHAD Gene

protein-coding   GIFtS: 56
GCID: GC17M048541

Chondroadherin

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
chondroadherin1 2
Chondroadherin Proteoglycan1 2
Cartilage Leucine-Rich Protein2 3
SLRR4A2 3

External Ids:    HGNC: 19091   Entrez Gene: 11012   Ensembl: ENSG000001364577   OMIM: 6021785   UniProtKB: O153353   

Export aliases for CHAD gene to outside databases

Previous GC identifers: GC17M048254 GC17M051023 GC17M048883 GC17M049016 GC17M045896 GC17M043909


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CHAD Gene:
Chondroadherin is a cartilage matrix protein thought to mediate adhesion of isolated chondrocytes. The protein
contains 11 leucine-rich repeats flanked by cysteine-rich regions. The chondroadherin messenger RNA is present in
chondrocytes at all ages. (provided by RefSeq, Jul 2008)

GeneCards Summary for CHAD Gene:
CHAD (chondroadherin) is a protein-coding gene. Diseases associated with CHAD include autoimmune hemolytic anemia, and hemolytic anemia. GO annotations related to this gene include extracellular matrix structural constituent. An important paralog of this gene is GP5.

UniProtKB/Swiss-Prot: CHAD_HUMAN, O15335
Function: Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least
for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important role in the regulation
of chondrocyte growth and proliferation (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NC_018928.2  NT_010783.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the CHAD gene promoter:
         NF-1/L   NF-1   p53   Brachyury   Pax-2   Pax-2a   HNF-4alpha2   HNF-4alpha1   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCHAD promoter sequence
   Search Chromatin IP Primers for CHAD

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CHAD


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.33   Ensembl cytogenetic band:  17q21.33   HGNC cytogenetic band: 17q21.33

CHAD Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CHAD gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M048541:  view genomic region     (about GC identifiers)

Start:
48,541,853 bp from pter      End:
48,546,327 bp from pter
Size:
4,475 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: CHAD_HUMAN, O15335 (See protein sequence)
Recommended Name: Chondroadherin precursor  
Size: 359 amino acids; 40476 Da
Subunit: Mostly monomeric (By similarity). Interacts with collagen type II
Secondary accessions: A8K812 Q6GTU0 Q96RJ5

Explore the universe of human proteins at neXtProt for CHAD: NX_O15335

Explore proteomics data for CHAD at MOPED

Post-translational modifications: 

  • Glycosylation2 at Ser144

  • See CHAD Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001258.2  
    ENSEMBL proteins: 
     ENSP00000425672   ENSP00000423812   ENSP00000258969  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SLRR: Proteoglycans / Extracellular Matrix : Small leucine-rich repeats

    4 InterPro protein domains:
     IPR000483 Cys-rich_flank_reg_C
     IPR001611 Leu-rich_rpt
     IPR003591 Leu-rich_rpt_typical-subtyp
     IPR000372 LRR-contain_N

    Graphical View of Domain Structure for InterPro Entry O15335

    ProtoNet protein and cluster: O15335

    2 Blocks protein domains:
    IPB000372 Cysteine-rich flanking region
    IPB000483 Cysteine-rich flanking region


    UniProtKB/Swiss-Prot: CHAD_HUMAN, O15335
    Similarity: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class IV subfamily
    Similarity: Contains 9 LRR (leucine-rich) repeats
    Similarity: Contains 1 LRRCT domain
    Similarity: Contains 1 LRRNT domain


    CHAD for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CHAD_HUMAN, O15335
    Function: Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least
    for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important role in the regulation
    of chondrocyte growth and proliferation (By similarity)

         Genatlas biochemistry entry for CHAD:
    chondroadherin,36kDa,expressed in chodrocytes,leucine-rich repeat (LRR) family

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005201extracellular matrix structural constituent ----
    GO:0005515protein binding ----
         
    CHAD for ontologies           About GeneDecksing


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Chad):
     adipose tissue  growth/size/body  skeleton 

    CHAD for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Chadtm1Gast for CHAD

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CHAD
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CHAD

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CHAD
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CHAD

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate CHAD (see all 12):
    hsa-miR-1226 hsa-miR-185* hsa-miR-222* hsa-miR-571 hsa-miR-199b-3p hsa-miR-199a-3p hsa-miR-3129-5p hsa-miR-545
    SwitchGear 3'UTR luciferase reporter plasmidCHAD 3' UTR sequence
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHAD


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CHAD_HUMAN, O15335: Secreted, extracellular space, extracellular matrix (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    cytosol1
    golgi apparatus1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005578proteinaceous extracellular matrix IEA--

    CHAD for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for CHAD About    
    See pathways by source

    SuperPathContained pathways About
    1Focal adhesion
    Focal adhesion0.65
    ECM-receptor interaction0.31
    Focal Adhesion0.65
    2PI3K-Akt signaling pathway
    PI3K-Akt signaling pathway

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for CHAD
        Focal Adhesion



    3 Kegg Pathways  (Kegg details for CHAD):
        PI3K-Akt signaling pathway
    Focal adhesion
    ECM-receptor interaction


    CHAD for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CHAD
    Interactions:

        Search GeneGlobe Interaction Network for CHAD

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for CHAD (O153353 ENSP000002589694) via UniProtKB, MINT, STRING, and/or I2D (see all 26)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    COL2A1P024583, ENSP000003698894I2D: score=1 STRING: ENSP00000369889
    ITGA1ENSP000002825884STRING: ENSP00000282588
    ITGA10ENSP000003583104STRING: ENSP00000358310
    ITGA11ENSP000003272904STRING: ENSP00000327290
    ITGA2ENSP000002965854STRING: ENSP00000296585
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001502cartilage condensation IEA--
    GO:0001558regulation of cell growth ----

    CHAD for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CHAD

    2 Novoseek inferred chemical compound relationships for CHAD gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    glycosaminoglycan 40.6 1 12354766 (1)
    leucine 36.5 3 15332017 (1), 17093390 (1)



    CHAD for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for CHAD gene: 
    NM_001267.2  

    Unigene Cluster for CHAD:

    Chondroadherin
    Hs.97220  [show with all ESTs]
    Unigene Representative Sequence: AK292177
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000506187 ENST00000508540(uc010dbr.3) ENST00000258969(uc010dbs.3)

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate CHAD (see all 12):
    hsa-miR-1226 hsa-miR-185* hsa-miR-222* hsa-miR-571 hsa-miR-199b-3p hsa-miR-199a-3p hsa-miR-3129-5p hsa-miR-545
    SwitchGear 3'UTR luciferase reporter plasmidCHAD 3' UTR sequence
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      QuantiFast Probe-based Assays in human, mouse, rat CHAD

    Additional mRNA sequence: 

    AF371328.1 AK292177.1 BC036360.1 BC073974.1 

    6 DOTS entries:

    DT.97765516  DT.100746839  DT.121003356  DT.315196  DT.97842206  DT.91832185 

    Selected AceView cDNA sequences (see all 65):

    BQ771633 CD611066 BC036360 CA419191 CA412761 BQ006680 BQ181527 CA418441 
    CA413462 BC073974 AW207201 BQ183620 CD611067 AI470540 BQ029011 BX095415 
    BQ044947 NM_001267 BQ573868 AF371328 BF196113 BU617709 BM988025 CN480369 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CHAD expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGCAATTTC
    CHAD Expression
    About this image


    CHAD expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 16 entries
             Osteochondro Mesenchymal Cells Vertebrae
             Zeugopod Long Bone
             Micromass-induced chondrocytes
     
     Cartilage (Muscoskeletal System)    fully expand to see all 13 entries
             Mesenchymal Condensate Cells Zeugopod
             Meckel's Cartilage
             Micromass-induced chondrocytes
     
     Limb (Muscoskeletal System)
             Mesenchymal Condensate Cells Zeugopod
     
     Blood (Hematopoietic System)
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
     
     Somite (Muscoskeletal System)
             Sacral Mesenchymal Sclerotome
    CHAD Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CHAD Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.97220

    UniProtKB/Swiss-Prot: CHAD_HUMAN, O15335
    Tissue specificity: Present in chondrocytes at all ages

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for CHAD gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Chad1 , 5 chondroadherin1, 5 87.44(n)1
    94.66(a)1
      11 (58.90 cM)5
    126431  NM_007689.41  NP_031715.11 
     945650475 
    chicken
    (Gallus gallus)
    Aves CHAD1 chondroadherin 71.61(n)
    67.36(a)
      769665  XM_004946335.1  XP_004946392.1 
    lizard
    (Anolis carolinensis)
    Reptilia CHAD6
    chondroadherin
    71(a)
    1 ↔ 1
    2(116276713-116290960)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia chad1 chondroadherin 68.84(n)
    68.25(a)
      101732210  XM_004918482.1  XP_004918539.1 
    zebrafish
    (Danio rerio)
    Actinopterygii chad1 chondroadherin 64.48(n)
    62.5(a)
      394038  NM_201063.1  NP_957357.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta haf6
    hattifattener
    7(a)
    1 → many
    2L(1555130-1608404)


    ENSEMBL Gene Tree for CHAD (if available)
    TreeFam Gene Tree for CHAD (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CHAD gene
    GP52  CPN22  LRIG32  LRRTM42  LRRC152  LRIG22  LRRTM32  IGFALS2  
    CHADL2  LRIG12  LRRTM22  LRRTM12  LRG12  
    5 SIMAP similar genes for CHAD using alignment to 2 protein entries:     CHAD_HUMAN (see all proteins):
    CHADL    LRRTM4    LRRTM2    LRRC4C    NGL1

    CHAD for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    3 SNPs for CHAD    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1470474481,2
    C--48543624(+) TTGTA-/TATTTT 1 -- int10--------
    rs352180931,2,4
    ----see VAR_0520192 mis40--------
    rs22315101,2,4
    ----see VAR_0306312 mis40--------

    HapMap Linkage Disequilibrium report for CHAD (48541853 - 48546327 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for CHAD:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv833476CNV Loss17160897
    nsv2081CNV Loss18451855
    dgv3228n71CNV Gain21882294
    nsv908600CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CHAD
    DNA2.0 Custom Variant and Variant Library Synthesis for CHAD

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 602178    OMIM disorders: --

    7 diseases for CHAD:    
    About MalaCards
    autoimmune hemolytic anemia    hemolytic anemia    osteoarthritis    rheumatoid arthritis
    arthritis    cervicitis    thyroiditis


    CHAD for disorders           About GeneDecksing


    Export disorders for CHAD gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CHAD gene, integrated from 10 sources (see all 27):
    (articles sorted by number of sources associating them with CHAD)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The structure and chromosome location of the human chondroadherin gene (CHAD). (PubMed id 9344663)1, 2, 3, 9 Grover J.... Roughley P.J. (Genomics 1997)
    2. Association of chondroadherin with collagen type II. (PubMed id 11445564)1, 2, 9 Maansson B.... Heinegaard D. (J. Biol. Chem. 2001)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Variation in chondroadherin abundance and fragmentation in the human scoliotic disc. (PubMed id 19525844)1, 9 Haglund L....Roughley P. (Spine 2009)
    5. Integrin alpha2beta1 is a receptor for the cartilage matrix protein chondroadherin. (PubMed id 9281592)1, 9 Camper L....Lundgren-Akerlund E. (J. Cell Biol. 1997)
    6. The C-terminal peptide of chondroadherin modulates cellular activity by selectively binding to heparan sulfate chains. (PubMed id 23172228)1 Haglund L....HeinegAYrd D. (J. Biol. Chem. 2013)
    7. Identification and characterization of the integrin alpha2beta1 binding motif in chondroadherin mediating cell attachment. (PubMed id 21127050)1 Haglund L....HeinegAYrd D. (J. Biol. Chem. 2011)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. Cartilage matrix proteins. A basic 36-kDa protein with a restricted distribution to cartilage and bone. (PubMed id 1939097)1 Larsson T....HeinegAYrd D. (J. Biol. Chem. 1991)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 1101 HGNC: 1909 AceView: CHAD Ensembl:ENSG00000136457 euGenes: HUgn1101
    ECgene: CHAD Kegg: 1101 H-InvDB: CHAD

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CHAD Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CHAD gene:
    Search GeneIP for patents involving CHAD

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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