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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CHAC1 Gene

protein-coding   GIFtS: 50
GCID: GC15P041245

ChaC, Cation Transport Regulator Homolog 1 (E. Coli)

(Previous names: ChaC, cation transport regulator-like 1 (E. coli))
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
ChaC, Cation Transport Regulator Homolog 1 (E. Coli)1 2     Cation Transport Regulator-Like Protein 12
Gamma-GCT Acting On Glutathione Homolog 11 2     ChaC, Cation Transport Regulator-Like 12
Blocks Notch Protein2 3     BOTCH3
ChaC, Cation Transport Regulator-Like 1 (E. Coli)1     Botch3
botch2     

External Ids:    HGNC: 286801   Entrez Gene: 790942   Ensembl: ENSG000001289657   OMIM: 6145875   UniProtKB: Q9BUX13   

Export aliases for CHAC1 gene to outside databases

Previous GC identifers: GC15P039033 GC15P018094


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for CHAC1 Gene: 
CHAC1 (ChaC, cation transport regulator homolog 1 (E. coli)) is a protein-coding gene. Diseases associated with CHAC1 include avian influenza, and influenza. GO annotations related to this gene include protein binding and Notch binding. An important paralog of this gene is CHAC2.

UniProtKB/Swiss-Prot: CHAC1_HUMAN, Q9BUX1
Function: Negative regulator of Notch signaling pathway involved in embryonic neurogenesis: acts by inhibiting
Notch cleavage by furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in
embryos. May also act as a pro-apoptotic component of the unfolded protein response pathway by mediating the
pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NC_018926.2  NT_010194.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CHAC1 gene promoter:
         TBP   C/EBPbeta   p53   FOXD1   Nkx2-5   E47   C/EBPalpha   AREB6   Hand1   Ik-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCHAC1 promoter sequence
   Search SABiosciences Chromatin IP Primers for CHAC1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHAC1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q15.1   Ensembl cytogenetic band:  15q15.1   HGNC cytogenetic band: 15q15.1

CHAC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CHAC1 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P041245:  view genomic region     (about GC identifiers)

Start:
41,245,160 bp from pter      End:
41,248,717 bp from pter
Size:
3,558 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CHAC1_HUMAN, Q9BUX1 (See protein sequence)
Recommended Name: Cation transport regulator-like protein 1  
Size: 264 amino acids; 28747 Da
Subunit: Interacts with NOTCH1 (via extracellular region) (By similarity)
Subcellular location: Golgi apparatus, trans-Golgi network (By similarity). Cytoplasm, cytosol
Caution: It is uncertain whether Met-1 or Met-43 is the initiator. Met-1 is not conserved in orthologs
Sequence caution: Sequence=AAH01683.1; Type=Erroneous initiation; Sequence=AAH01847.1; Type=Erroneous initiation;
Sequence=AAH19625.1; Type=Erroneous initiation; Sequence=AAW23972.1; Type=Erroneous initiation;
Secondary accessions: Q0VIA0
Alternative splicing: 2 isoforms:  Q9BUX1-1   Q9BUX1-2   

Explore the universe of human proteins at neXtProt for CHAC1: NX_Q9BUX1

Explore proteomics data for CHAC1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BUX1

  • CHAC1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CHAC1 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001136248.1  NP_077016.2  

    ENSEMBL proteins: 
     ENSP00000395466   ENSP00000398105   ENSP00000452707  

    Human Recombinant Protein Products for CHAC1: 
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    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CHAC1 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005794Golgi apparatus IEA--
    GO:0005802trans-Golgi network ISS--
    GO:0005829cytosol IDA19109178

    CHAC1 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for CHAC1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR013024 Butirosin_synth_BtrG-like
     IPR006840 ChaC

    Graphical View of Domain Structure for InterPro Entry Q9BUX1

    ProtoNet protein and cluster: Q9BUX1

    UniProtKB/Swiss-Prot: CHAC1_HUMAN, Q9BUX1
    Similarity: Belongs to the ChaC family


    CHAC1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CHAC1_HUMAN, Q9BUX1
    Function: Negative regulator of Notch signaling pathway involved in embryonic neurogenesis: acts by inhibiting
    Notch cleavage by furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in
    embryos. May also act as a pro-apoptotic component of the unfolded protein response pathway by mediating the
    pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade
    Induction: Induced by chemical activators of the unfolded protein response (UPR) such as tunicamycin, DTT and
    thapsigargin

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005112Notch binding ISS--
    GO:0005515protein binding IPI16189514
         
    CHAC1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for CHAC1:
     Big cells  Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for CHAC1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CHAC1

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    miRNA
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    8/22 QIAGEN miScript miRNA Assays for microRNAs that regulate CHAC1 (see all 22):
    hsa-miR-4291 hsa-miR-498 hsa-miR-15a hsa-miR-503 hsa-miR-4267 hsa-miR-1297 hsa-miR-424 hsa-miR-637
    SwitchGear 3'UTR luciferase reporter plasmidCHAC1 3' UTR sequence
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    Gene Editing
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    Clone
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CHAC1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    5 Interacting proteins for CHAC1 (Q9BUX11, 2, 3 ENSP000003981054) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RHOXF2Q9BQY41, 2, 3, ENSP000003604414EBI-751127,EBI-372094 MINT-68021 I2D: score=6 STRING: ENSP00000360441
    EIF5AP632413I2D: score=5 
    PMPCBO754393I2D: score=5 
    FEM1BQ9UK733I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006986response to unfolded protein IEA--
    GO:0007219Notch signaling pathway IEA--
    GO:0010955negative regulation of protein processing IMP--
    GO:0022008neurogenesis ISS--
    GO:0045746negative regulation of Notch signaling pathway IMP--

    CHAC1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CHAC1

    Search CenterWatch for drugs/clinical trials and news about CHAC1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CHAC1 gene (2 alternative transcripts): 
    NM_001142776.1  NM_024111.3  

    Unigene Cluster for CHAC1:

    ChaC, cation transport regulator homolog 1 (E. coli)
    Hs.155569  [show with all ESTs]
    Unigene Representative Sequence: BM455698
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000444189 ENST00000446533(uc010uct.1 uc001znh.2) ENST00000487220

    miRNA
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    8/22 QIAGEN miScript miRNA Assays for microRNAs that regulate CHAC1 (see all 22):
    hsa-miR-4291 hsa-miR-498 hsa-miR-15a hsa-miR-503 hsa-miR-4267 hsa-miR-1297 hsa-miR-424 hsa-miR-637
    SwitchGear 3'UTR luciferase reporter plasmidCHAC1 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CHAC1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHAC1

    Additional mRNA sequence: 

    AY702027.1 BC001683.1 BC001847.2 BC019625.1 

    2 DOTS entries:

    DT.427905  DT.100722454 

    24/128 AceView cDNA sequences (see all 128):

    BX366092 BX341274 BQ229688 CR591065 AL555217 CR598230 BM768609 NM_024111 
    CR620504 BX342065 CR601069 CR598799 CR617904 BI826016 CR624884 BX387147 
    BX421579 BM850339 AW964098 BC019625 AA357110 CR604510 BI756086 CR592413 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CHAC1 expression in normal human tissues (normalized intensities)      CHAC1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGGAGAAGGA
    CHAC1 Expression
    About this image


    CHAC1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/6 selected tissues (see all 6) fully expand
     
     Uterus (Reproductive System)    fully expand to see all 2 entries
             endometrial endothelial cell   
     
     Fibroblast (Uncategorized)    fully expand to see all 2 entries
             Human Prostate Fibroblasts (HPrF)   
     
     Ovary (Reproductive System)
             Secondary follicles
     
     Neuron (Nervous System)
             nerve   
     
     Lymph (Cardiovascular System)
             Human Lymphatic Fibroblasts (HLF)   

    See CHAC1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CHAC1

    SOURCE GeneReport for Unigene cluster: Hs.155569
        SABiosciences Custom PCR Arrays for CHAC1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHAC1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CHAC1 gene from 9/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Chac11 , 5 ChaC, cation transport regulator-like 1 (E. coli)5
    ChaC, cation transport regulator 11
    84.31(n)1
    88.24(a)1
      2 (59.97 cM)5
    690651  NM_026929.41  NP_081205.11 
     1193512295 
    chicken
    (Gallus gallus)
    Aves CHAC11 ChaC, cation transport regulator homolog 1 (E. coli) 68.7(n)
    64.32(a)
      423209  NM_001199656.1  NP_001186585.1 
    lizard
    (Anolis carolinensis)
    Reptilia CHAC16
    Uncharacterized protein
    54(a)
    1 ↔ 1
    GL343264.1(7037-12690)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.126422 Xenopus laevis transcribed sequence with weak similarity more 74.92(n)    CA790586.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.242392 Transcribed sequence with weak similarity to protein more 72.68(n)    CD778027.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG103656
    --
    35(a)
    1 ↔ 1
    3R(19549086-19557227)
    worm
    (Caenorhabditis elegans)
    Secernentea F22F7.71 Protein F22F7.7 47.93(n)
    39.3(a)
      178693  NM_071177.2  NP_503578.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes YER163C6
    Putative protein of unknown function; green fluore...
    26(a)
    1 → many
    V(503084-503782)
    wheat
    (Triticum aestivum)
    Liliopsida Ta.94522 Triticum aestivum transcribed sequence with weak similarity more 75(n)    BJ226799.1 


    ENSEMBL Gene Tree for CHAC1 (if available)
    TreeFam Gene Tree for CHAC1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CHAC1 gene
    CHAC22  
    1 SIMAP similar gene for CHAC1 using alignment to 2 protein entries:     CHAC1_HUMAN (see all proteins):
    CHAC2

    CHAC1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/134 SNPs in CHAC1 are shown (see all 134)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1474517801,2
    C--41243726(+) GAGGCA/GGAGGT 2 -- us2k10--------
    rs1918466171,2
    C--41243760(+) CTGCAC/GTCCAG 2 -- us2k10--------
    rs584329761,2
    C--41243817(+) AAAAA-/AAAAA 
     AAAAAAA
    GTAAC
    2 -- us2k11Minor allele frequency- AAAAAAAAAAAA:0.00NA 2
    rs1842699021,2
    --41243969(+) TTGTTC/TGTGCC 2 -- us2k10--------
    rs1886112641,2
    --41243982(+) TTCAGA/GTACTT 2 -- us2k10--------
    rs1931934711,2
    --41244015(+) TCCCAC/GTTCCC 2 -- us2k10--------
    rs1141137081,2
    F--41244023(+) CCCGGA/TCTACA 2 -- us2k11Minor allele frequency- T:0.01WA 118
    rs1851558531,2
    --41244100(+) ATGAAC/TGAAAG 2 -- us2k10--------
    rs1906469811,2
    --41244141(+) AATGTC/GGGAAA 2 -- us2k10--------
    rs1819482861,2
    C--41244158(+) GAAAGC/GGAAAA 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for CHAC1 (41245160 - 41248717 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for CHAC1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv1504CNV Insertion18451855
    dgv2360n71CNV Loss21882294
    nsv904106CNV Loss21882294
    nsv904101CNV Loss21882294

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 614587    OMIM disorders: --

    4 diseases for CHAC1:    About MalaCards
    avian influenza    influenza    ovarian cancer    gastric cancer


    CHAC1 for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: CHAC1 (1 document)

    Export disorders for CHAC1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CHAC1 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with CHAC1)
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    1. CHAC1/MGC4504 is a novel proapoptotic component of the unfolded protein response, downstream of the ATF4-ATF3-CHOP cascade. (PubMed id 19109178)1, 2, 9 Mungrue I.N.... Lusis A.J. (2009)
    2. Mammalian proapoptotic factor ChaC1 and its homologues function as g-glutamyl cyclotransferases acting specifically on glutathione. (PubMed id 23070364)1, 3 Kumar A....Bachhawat A.K. (2012)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Elevated mRNA expression of CHAC1 splicing variants i s associated with poor outcome for breast and ovarian cancer patients. (PubMed id 22108517)1 Goebel G....Fiegl H. (2012)
    5. Botch promotes neurogenesis by antagonizing Notch. (PubMed id 22445366)2 Chi Z.... Dawson V.L. (2012)
    6. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PubMed id 22589738)1 Fox C.S....Borecki I.B. (2012)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    8. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    9. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    10. Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)2 Zody M.C....Nusbaum C. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79094 HGNC: 28680 AceView: MGC4504 Ensembl:ENSG00000128965 euGenes: HUgn79094
    ECgene: CHAC1 H-InvDB: CHAC1

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CHAC1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CHAC1 gene:
    Search GeneIP for patents involving CHAC1

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