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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CHAC1 Gene

protein-coding   GIFtS: 48
GCID: GC15P041245

ChaC, cation transport regulator homolog 1 (E. coli)

(Previous names: ChaC, cation transport regulator-like 1 (E. coli) )
 Explore 4 diseases affiliated with
CHAC1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for CHAC1    

Aliases
for CHAC1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
ChaC, Cation Transport Regulator Homolog 1 (E. Coli)1 2     Cation Transport Regulator-Like Protein 12
Blocks Notch Protein2 3     ChaC, Cation Transport Regulator-Like 12
MGC45041     BOTCH3
ChaC, Cation Transport Regulator-Like 1 (E. Coli)1     Botch3
Botch3     

External Ids:    HGNC: 286801   Entrez Gene: 790942   Ensembl: ENSG000001289657   OMIM: 6145875   UniProtKB: Q9BUX13   

Export aliases for CHAC1 gene to outside databases

Previous GC identifers: GC15P039033 GC15P018094


Summaries
for CHAC1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: CHAC1_HUMAN, Q9BUX1
Function: Negative regulator of Notch signaling pathway involved in embryonic neurogenesis: acts by inhibiting Notch
cleavage by furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in embryos. May also
act as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of
the ATF4-ATF3-DDIT3/CHOP cascade




Genomic Views
for CHAC1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NC_018926.1  NT_010194.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CHAC1 gene promoter:
         TBP   C/EBPbeta   p53   FOXD1   Nkx2-5   E47   C/EBPalpha   AREB6   Hand1   Ik-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CHAC1 promoter sequence
   Search SABiosciences Chromatin IP Primers for CHAC1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CHAC1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q15.1   Ensembl cytogenetic band:  15q15.1   HGNC cytogenetic band: 15q15.1

CHAC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CHAC1 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P041245:  view genomic region     (about GC identifiers)

Start:
 41,245,160 bp from pter      End:
 41,248,717 bp from pter
Size:
 3,558 bases      Orientation:
 plus strand

Proteins
for CHAC1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CHAC1_HUMAN, Q9BUX1 (See protein sequence)
Recommended Name: Cation transport regulator-like protein 1  
Size: 264 amino acids; 28747 Da
Subunit: Interacts with NOTCH1 (via extracellular region) (By similarity)
Subcellular location: Golgi apparatus, trans-Golgi network (By similarity). Cytoplasm, cytosol
Caution: It is uncertain whether Met-1 or Met-43 is the initiator. Met-1 is not conserved in orthologs
Sequence caution: Sequence=AAH01683.1; Type=Erroneous initiation; Sequence=AAH01847.1; Type=Erroneous initiation;
Sequence=AAH19625.1; Type=Erroneous initiation; Sequence=AAW23972.1; Type=Erroneous initiation;
Secondary accessions: Q0VIA0
Alternative splicing: 2 isoforms:  Q9BUX1-1   Q9BUX1-2   

Explore the universe of human proteins at neXtProt for CHAC1: NX_Q9BUX1

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9BUX1

    • CHAC1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001136248.1  NP_077016.2  

    ENSEMBL proteins: 
     ENSP00000395466   ENSP00000398105   ENSP00000452707  

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    Novus Biologicals CHAC1 Lysate
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    Uscn Proteins for CHAC1

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005794Golgi apparatus IEA--
    GO:0005802trans-Golgi network ISS--
    GO:0005829cytosol IDA19109178


    CHAC1 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for CHAC1

    Protein Domains /
    Families
    for CHAC1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    CHAC1 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR013024 Butirosin_synth_BtrG-like
     IPR006840 ChaC

    Graphical View of Domain Structure for InterPro Entry Q9BUX1

    ProtoNet protein and cluster: Q9BUX1

    UniProtKB/Swiss-Prot: CHAC1_HUMAN, Q9BUX1
    Similarity: Belongs to the chaC family


    Function
    for CHAC1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: CHAC1_HUMAN, Q9BUX1
    Function: Negative regulator of Notch signaling pathway involved in embryonic neurogenesis: acts by inhibiting Notch
    cleavage by furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in embryos. May also
    act as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of
    the ATF4-ATF3-DDIT3/CHOP cascade
    Induction: Induced by chemical activators of the unfolded protein response (UPR) such as tunicamycin, DTT and
    thapsigargin

    miRNA
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    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CHAC1
    8/22 QIAGEN miScript miRNA Assays for microRNAs that regulate CHAC1 (see all 22):
    hsa-miR-4291 hsa-miR-498 hsa-miR-15a hsa-miR-503 hsa-miR-4267 hsa-miR-1297 hsa-miR-424 hsa-miR-637
    SwitchGear 3'UTR luciferase reporter plasmid: CHAC1 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: CHAC1
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    Gene Editing
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    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for CHAC1

    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005112Notch binding ISS--
    GO:0005515protein binding IPI16189514


    CHAC1 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for CHAC1:
     Big cells  Increased gamma-H2AX phosphory 


    Pathways & Interactions
    for CHAC1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CHAC1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    5 Interacting proteins for CHAC1 (Q9BUX11, 2, 3 ENSP000003981054) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RHOXF2Q9BQY41, 2, 3, ENSP000003604414EBI-751127,EBI-372094 MINT-68021 I2D: score=6 STRING: ENSP00000360441
    EIF5AP632413I2D: score=5 
    PMPCBO754393I2D: score=5 
    FEM1BQ9UK733I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006986response to unfolded protein IEA--
    GO:0007219Notch signaling pathway IEA--
    GO:0010955negative regulation of protein processing IMP--
    GO:0022008neurogenesis ISS--
    GO:0045746negative regulation of Notch signaling pathway IMP--


    CHAC1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for CHAC1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CHAC1
    Search CenterWatch for drugs/clinical trials and news about CHAC1 

    Transcripts
    for CHAC1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for CHAC1 gene (2 alternative transcripts): 
    NM_001142776.1  NM_024111.3  

    Unigene Cluster for CHAC1:

    ChaC, cation transport regulator homolog 1 (E. coli)
    Hs.155569  [show with all ESTs]
    Unigene Representative Sequence: BM455698
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000444189 ENST00000446533(uc010uct.1 uc001znh.2) ENST00000487220


    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CHAC1
    8/22 QIAGEN miScript miRNA Assays for microRNAs that regulate CHAC1 (see all 22):
    hsa-miR-4291 hsa-miR-498 hsa-miR-15a hsa-miR-503 hsa-miR-4267 hsa-miR-1297 hsa-miR-424 hsa-miR-637
    SwitchGear 3'UTR luciferase reporter plasmid: CHAC1 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: CHAC1
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CHAC1
    Clone
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    Primer
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CHAC1

    Additional cDNA sequence: 

    AY702027.1 BC001683.1 BC001847.2 BC019625.1 

    2 DOTS entries:

    DT.427905  DT.100722454 

    24/128 AceView cDNA sequences (see all 128):

    BX342065 BM850339 BQ229688 BQ221809 CR592413 AW964098 NM_024111 AL555217 
    CR617904 BX387147 BX421579 CR601069 BX366092 CR604510 AI433067 BI756086 
    BC019625 CR624884 CB529304 CR620504 AL524642 BI826016 CR598230 CR598799 

    GeneLoc Exon Structure


    Expression
    for CHAC1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CHAC1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AGGAGAAGGA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    CHAC1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 3 LifeMap Cells 
    NameCategory
    Secondary follicles (Primary Cell)Ovary, Reproductive System
    Intervertebral disc (IVD) annulus fibrosus (AF) cells (Differentiation of s...)Cartilage
    Cartilage-like cells (Differentiation of s...)Cartilage
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See CHAC1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CHAC1

    SOURCE GeneReport for Unigene cluster: Hs.155569
        SABiosciences Custom PCR Arrays for CHAC1
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CHAC1

    Orthologs
    for CHAC1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the last universal common ancestor (LUCA).

    Orthologs for CHAC1 gene from 10/26 species (see all 26)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Chac11 , 5 ChaC, cation transport regulator-like 1 (E. coli)5
    ChaC, cation transport regulator 11    		 84.31(n)1
    88.24(a)1    		   2 (59.97 cM)5
    690651  NM_026929.41  NP_081205.11 
     1193512295 
    chicken
    (Gallus gallus)    		 Aves CHAC11 ChaC, cation transport regulator homolog 1 (E. coli) 68.7(n)
    64.32(a)    		   423209  NM_001199656.1  NP_001186585.1 
    lizard
    (Anolis carolinensis)    		 Reptilia CHAC16
    		 --
    		 54(a)
    		 1 ↔ 1
    		 GL343264.1(8850-12342)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.126422 Xenopus laevis transcribed sequence with weak similarity more 74.92(n)    CA790586.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii Dr.242392 Transcribed sequence with weak similarity to protein more 72.68(n)    CD778027.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG103656
    		 --
    		 33(a)
    		 1 ↔ 1
    		 3R(19549086-19557227)
    worm
    (Caenorhabditis elegans)    		 Secernentea F22F7.71 Protein F22F7.7 47.93(n)
    39.3(a)    		   178693  NM_071177.2  NP_503578.1 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT1G447906
    AT5G262206
    (see all 3)    		 ChaC-like family protein
    (see all 3)    		 36(a)
    29(a)
    (see all 3)    		 many ↔ many
    many ↔ many
    (see all 3)    		 1(16912154-16913664)
    5(9162969-9164685)
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    		 cation transport regulator-like protein 1, putativ...
    cation transport regulator-like protein 1, putativ...
    		 42(a)
    30(a)
    		 many ↔ many
    many ↔ many
    		 4(22169830-22172882)
    2(15670353-15673819)
    E. coli
    (Escherichia coli)    		 Gamma proteobacteria chaC6
    		 cation transport regulator
    		 25(a)
    		 1 → many
    		 Chromosome(1271730-1272425)


    ENSEMBL Gene Tree for CHAC1 (if available)
    TreeFam Gene Tree for CHAC1 (if available) 

    Paralogs
    for CHAC1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CHAC1 gene
    CHAC22  
    1 SIMAP similar gene for CHAC1 using alignment to 2 protein entries:     CHAC1_HUMAN (see all proteins):
    CHAC2

    CHAC1 for paralogs           About GeneDecksing



    Genomic Variants
    for CHAC1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/113 NCBI SNPs in CHAC1 are shown (see all 113)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 15 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1474517801,2
    		--41243726(+) GAGGCA/GGAGGT 2 -- us2k10--------
    rs1918466171,2
    		--41243760(+) CTGCAC/GTCCAG 2 -- us2k10--------
    rs584329761,2
    		C--41243794(+) AAAAA-/AAAAA 
     AAAAAAA    GTAAC     		2 -- us2k11Minor allele frequency- AAAAAAAAAAAA:0.00NA 2
    rs1842699021,2
    		--41243969(+) TTGTTC/TGTGCC 2 -- us2k10--------
    rs1886112641,2
    		--41243982(+) TTCAGA/GTACTT 2 -- us2k10--------
    rs1931934711,2
    		--41244015(+) TCCCAC/GTTCCC 2 -- us2k10--------
    rs1141137081,2
    		--41244023(+) CCCGGA/TCTACA 2 -- us2k11Minor allele frequency- T:0.01WA 118
    rs1851558531,2
    		--41244100(+) ATGAAC/TGAAAG 2 -- us2k10--------
    rs1906469811,2
    		--41244141(+) AATGTC/GGGAAA 2 -- us2k10--------
    rs1819482861,2
    		--41244158(+) GAAAGC/GGAAAA 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for CHAC1 (41245160 - 41248717 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for CHAC1: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CHAC1
    DNA2.0 Custom Variant and Variant Library Synthesis for CHAC1

    Disorders / Diseases
    for CHAC1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    CHAC1 for disorders           About GeneDecksing

    OMIM gene information: 614587    OMIM disorders: --

    4 diseases for CHAC1:    About MalaCards
    avian influenza    breast-ovarian cancer    ovarian cancer    influenza

    Human Genome Epidemiology (HuGE) Navigator: CHAC1 (1 document)

    Export disorders for CHAC1 gene to outside databases

    Publications
    for CHAC1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CHAC1 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with CHAC1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. CHAC1/MGC4504 is a novel proapoptotic component of the unfolded protein response, downstream of the ATF4-ATF3-CHOP cascade. (PubMed id 19109178)1, 2, 9 Mungrue I.N.... Lusis A.J. (2009)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Elevated mRNA expression of CHAC1 splicing variants i s associated with poor outcome for breast and ovarian cancer patients. (PubMed id 22108517)1 Goebel G....Fiegl H. (2012)
    4. Botch promotes neurogenesis by antagonizing Notch. (PubMed id 22445366)2 Chi Z.... Dawson V.L. (2012)
    5. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PubMed id 22589738)1 Fox C.S....Borecki I.B. (2012)
    6. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    7. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    8. Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)2 Zody M.C....Nusbaum C. (2006)
    9. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
    10. Transcriptome analysis of human gastric cancer. (PubMed id 16341674)1 Oh J.H....Kim N.S. (2005)

    External Searches for CHAC1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing CHAC1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 79094 HGNC: 28680 AceView: MGC4504 Ensembl:ENSG00000128965 euGenes: HUgn79094
    ECgene: CHAC1 H-InvDB: CHAC1

    Other Databases showing CHAC1 gene

    (According to HUGE)
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    Specialized Databases showing CHAC1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CHAC1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for CHAC1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    		Patent Information for CHAC1 gene:
    Search GeneIP for patents involving CHAC1

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