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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CGB7 Gene

protein-coding   GIFtS: 50
GCID: GC19M049557

Chorionic Gonadotropin, Beta Polypeptide 7

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Chorionic Gonadotropin, Beta Polypeptide 71 2     CG-beta3
CG-beta-a2     CGB33
CGB62     Chorionic Gonadotrophin Chain Beta3
Chorionic Gonadotropin Beta 7 Subunit2     

External Ids:    HGNC: 164511   Entrez Gene: 940272   Ensembl: ENSG000001963377   OMIM: 6088265   UniProtKB: P012333   

Export aliases for CGB7 gene to outside databases

Previous GC identifers: GC19M050215 GC19M049920 GC19M054233 GC19M054242 GC19M054249 GC19M045934


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CGB7 Gene:
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 7 subunit of chorionic
gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta
subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and
stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta
subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and
contiguous with the luteinizing hormone beta subunit gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for CGB7 Gene: 
CGB7 (chorionic gonadotropin, beta polypeptide 7) is a protein-coding gene. Diseases associated with CGB7 include gestational choriocarcinoma, and ulcerative stomatitis. An important paralog of this gene is TSHB.

UniProtKB/Swiss-Prot: CGHB_HUMAN, P01233
Function: Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy

Gene Wiki entry for CGB7 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NT_011109.16  NC_018930.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CGB7 gene promoter:
         Pax-5   p53   NF-YA   Egr-4   NF-YB   CBF-A   CBF-B   CP1A   NF-Y   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCGB7 promoter sequence
   Search SABiosciences Chromatin IP Primers for CGB7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CGB7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.32   Ensembl cytogenetic band:  19q13.33   HGNC cytogenetic band: 19q13.32

CGB7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CGB7 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M049557:  view genomic region     (about GC identifiers)

Start:
49,557,531 bp from pter      End:
49,562,117 bp from pter
Size:
4,587 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CGHB_HUMAN, P01233 (See protein sequence)
Recommended Name: Choriogonadotropin subunit beta precursor  
Size: 165 amino acids; 17739 Da
Subunit: Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to
thyrotropin, lutropin, follitropin and gonadotropin
Subcellular location: Secreted
Developmental stage: Made by the first trimester placenta
Sequence caution: Sequence=CAA25068.1; Type=Erroneous initiation; Sequence=CAA25069.1; Type=Erroneous initiation;
4 PDB 3D structures from and Proteopedia for CGB7:
1HCN (3D)        1HRP (3D)        1QFW (3D)        1XUL (3D)    
Secondary accessions: A1A5E0 B9ZVP5 Q13991 Q14000 Q3KPI3 Q3SY41 Q8WTT5 Q8WXL1 Q8WXL2 Q8WXL3
Q8WXL4
Alternative splicing: 2 isoforms:  P01233-1   P01233-2   (Ref.2 (CAA25069) sequence is in conflict in positions: 7:G->R, 9:A->V, 12:D->G)

Explore the universe of human proteins at neXtProt for CGB7: NX_P01233

Explore proteomics data for CGB7 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P01233

  • CGB7 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CGB7 Protein Expression
    REFSEQ proteins: NP_149133.1  
    ENSEMBL proteins: 
     ENSP00000469076   ENSP00000470813   ENSP00000366493   ENSP00000348545  
    Reactome Protein details: P01233
    Human Recombinant Protein Products for CGB7: 
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    Sino Biological Recombinant Protein for CGB7
    Sino Biological Cell Lysate for CGB7 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region ----

    CGB7 for ontologies           About GeneDecksing



    CGB7 Antibody Products: 
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    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR018245 Gonadotropin_bsu_CS
     IPR001545 Gonadotropin_bsu
     IPR006208 Cys_knot

    Graphical View of Domain Structure for InterPro Entry P01233

    ProtoNet protein and cluster: P01233

    3 Blocks protein domains:
    IPB001545 Gonadotropin
    IPB002400 Growth factor cystine knot superfamily signature
    IPB006208 Cystine knot domain


    UniProtKB/Swiss-Prot: CGHB_HUMAN, P01233
    Similarity: Belongs to the glycoprotein hormones subunit beta family


    CGB7 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CGHB_HUMAN, P01233
    Function: Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005179hormone activity ----
         
    CGB7 for ontologies           About GeneDecksing


    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for CGB7 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Selected targets of Oct-3/4
    Selected targets of Oct-3/4

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 EMD Millipore Pathway for CGB7
        Selected targets of Oct-3/4



    4        Reactome Pathways for CGB7
        Peptide hormone biosynthesis
    Metabolism of proteins
    Glycoprotein hormones
    Peptide hormone metabolism



    CGB7 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CGB7

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    5 Interacting proteins for CGB7 (P012332, 3 ENSP000003485454) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CGAP012152, 3, ENSP000003585954MINT-24926 I2D: score=5 STRING: ENSP00000358595
    CKBP122773I2D: score=1 
    EWSR1Q018443I2D: score=1 
    FSHBP012253I2D: score=1 
    LHCGRP228883I2D: score=1 
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915apoptotic process ----
    GO:0007165signal transduction ----
    GO:0007267cell-cell signaling ----
    GO:0007292female gamete generation ----
    GO:0016486peptide hormone processing ----

    CGB7 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    CGB7 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CGB7 (CGHB)

    UniProtKB/Swiss-Prot: CGHB_HUMAN, P01233
    Pharmaceutical: Available under the names Novarel (Ferring) and Profasi (Serono). Used as adjunctive therapy in
    the treatment of obesity. There is no substantial evidence that it increases weight loss beyond that resulting
    from caloric restriction, that it causes a more attractive or 'normal' distribution of fat, or that it decreases
    the hunger and discomfort associated with calorie-restricted diets

    10/14 Novoseek inferred chemical compound relationships for CGB7 gene (see all 14)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    oestriol 77 10 10073912 (1), 15512289 (1), 9203211 (1), 10416963 (1) (see all 8)
    methotrexate 49.9 9 9740461 (1), 17356825 (1), 18751412 (1), 14530615 (1) (see all 7)
    ctp 49.4 8 17092639 (3), 16636974 (1), 16644100 (1), 1379674 (1) (see all 5)
    progesterone 34.9 10 1379268 (2), 10656995 (1), 1379267 (1), 12581973 (1) (see all 9)
    etoposide 25 1 7532652 (1)
    bleomycin 20.2 1 18751412 (1)
    cisplatin 14.3 1 18751412 (1)
    gnrh 4.32 1 8096491 (1)
    estradiol 0 3 1833973 (2), 11078984 (1)
    lactate 0 3 17122498 (1), 16474737 (1), 1716953 (1)

    Search CenterWatch for drugs/clinical trials and news about CGB7 / CGHB

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CGB7 gene: 
    NM_033142.1  

    Unigene Clusters for CGB7:

    Chorionic gonadotropin, beta polypeptide 7
    Hs.681647  [show with all ESTs], Hs.745468  [show with all ESTs]
    Unigene Representative Sequences: NM_033142, AK092722
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000596965 ENST00000597853 ENST00000593309 ENST00000598442 ENST00000377280
    ENST00000356213(uc002pmc.3 uc002pmd.3 uc002pme.3 uc010emq.1)

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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CGB7 (NM_033142)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CGB7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CGB7
    Sirion Biotech Customized lentivirus for stable overexpression of CGB7 
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    Primer
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    OriGene qPCR primer pairs and template standards for CGB7
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CGB7
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    Additional mRNA sequence: 

    AK092722.1 AK310581.1 BC041054.1 

    4 DOTS entries:

    DT.119691  DT.100837633  DT.40234754  DT.102832971 

    24/409 AceView cDNA sequences (see all 409):

    NM_033142 CR613376 CF527874 CF528345 CF528125 AI188689 AU138071 CF527932 
    BU752328 BU752823 CF528062 CF528112 CF528202 NM_000737 CF528337 H95121 
    BQ007403 CF527846 CF528140 CF528240 BQ007360 CF527771 BM977377 BX359929 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CGB7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    CGB7 Expression
    About this image


    See CGB7 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CGB7

    SOURCE GeneReport for Unigene clusters: Hs.681647 Hs.745468

    UniProtKB/Swiss-Prot: CGHB_HUMAN, P01233
    Tissue specificity: Placenta

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for CGB7 gene from 3/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    39(a)
    1 → many
    6(80158039-80158659)
    zebrafish
    (Danio rerio)
    Actinopterygii lhb1 luteinizing hormone, beta polypeptide 57.43(n)
    49.5(a)
      402917  NM_205622.2  NP_991185.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Gpb56
    Glycoprotein hormone beta 5
    13(a)
    1 → many
    2LHet(167215-167979)
            Species with no ortholog for CGB7

    ENSEMBL Gene Tree for CGB7 (if available)
    TreeFam Gene Tree for CGB7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CGB7 gene
    TSHB2  FSHB2  CGB22  LHB2  CGB82  ENSG000002673352  CGB52  CGB2  
    CGB12  
    8 SIMAP similar genes for CGB7 using alignment to 2 protein entries:     CGHB_HUMAN (see all proteins):
    CGB8    CGB2    CGB    CGB5    CGB1    LHB
    FSHB    TSHB

    CGB7 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/135 SNPs in CGB7 are shown (see all 135)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1504109931,2
    --49557049(+) ACCTCC/TTGAGC 1 -- ds50010--------
    rs3733373451,2
    C--49557117(+) TCTTT-/TTTTTT 1 -- ds50010--------
    rs1115545681,2
    C,F--49557145(+) GTCTCG/CCTCCG 1 -- ds50011Minor allele frequency- C:0.50CSA 2
    rs801985561,2
    C--49557150(+) GCTCCG/ATCATG 1 -- ds50011Minor allele frequency- A:0.50CSA 2
    rs1451680861,2
    --49557202(+) TCCCCC/GTCCCA 1 -- ds50010--------
    rs789925681,2
    C--49557355(+) TGATCC/AGCCTG 1 -- ds50011Minor allele frequency- A:0.00CSA 1
    rs353361691,2
    C,F--49557372(-) ACTTTG/CGGAGG 1 -- ds50013Minor allele frequency- C:0.32EU WA EA 190
    rs1452453341,2
    C--49557392(+) ACAGGC/GGTGAG 1 -- ds50010--------
    rs355947691,2
    C,F--49557408(-) CGGCKG/AGGCGC 1 -- ds50013Minor allele frequency- A:0.01EU WA EA 190
    rs347264181,2
    C,F--49557409(-) ACGGCG/TGGGCG 1 -- ds50016Minor allele frequency- T:0.36EU WA EA NA CSA 195

    HapMap Linkage Disequilibrium report for CGB7 (49557531 - 49562117 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/11 variations for CGB7 (see all 11):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2675899CNV Deletion23128226
    nsv833859CNV Loss17160897
    nsv912248CNV Loss21882294
    nsv833857CNV Loss17160897
    nsv912251CNV Loss21882294
    dgv3970n71CNV Loss21882294
    nsv912252CNV Loss21882294
    dgv592n67CNV Loss20364138
    nsv520785CNV Gain19592680
    esv22462CNV Gain19812545

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 608826    OMIM disorders: --

    20/46 diseases for CGB7 (see all 46):    About MalaCards
    gestational choriocarcinoma    ulcerative stomatitis    3-methylcrotonyl-coa carboxylase deficiency    mixed ductal-endocrine carcinoma
    nonseminomatous germ cell tumor    seminoma    sacrococcygeal teratoma    ectopic pregnancy
    choriocarcinoma    teratoma    smith-lemli-opitz syndrome    stomatitis
    congenital diaphragmatic hernia    bladder carcinoma    cryptococcosis    thyrotoxicosis
    germinoma    neural tube defects    pituitary tumors    hernia

    1 disease from the University of Copenhagen DISEASES database for CGB7:
    Cryptococcosis

    CGB7 for disorders           About GeneDecksing

    10/32 Novoseek inferred disease relationships for CGB7 gene (see all 32)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    down syndrome 87.7 53 7693095 (3), 7506599 (2), 10073912 (1), 11559909 (1) (see all 47)
    choriocarcinoma 73.4 9 1649392 (1), 20415215 (1), 10341006 (1), 8883763 (1) (see all 6)
    pregnancy ectopic 69.5 13 1379268 (2), 1826038 (1), 8501201 (1), 16123088 (1) (see all 11)
    trisomy 66.6 15 7506599 (4), 9238717 (1), 20101668 (1), 11559905 (1) (see all 12)
    pregnancy tubal 59.4 3 7769076 (1), 8530682 (1), 8671345 (1)
    seminoma 53.2 4 11005453 (1), 18578862 (1), 1716953 (1), 8653285 (1)
    hydatidiform mole 51.3 2 8883763 (2)
    teratoma 43.6 1 9021828 (1)
    carcinoma embryonal 33.7 1 11005453 (1)
    chromosomal aberrations 31.7 2 9313073 (1), 8284287 (1)


    Export disorders for CGB7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CGB7 gene, integrated from 9 sources (see all 268):
    (articles sorted by number of sources associating them with CGB7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The beta subunit of human chorionic gonadotropin is encoded by multiple genes. (PubMed id 6194155)1, 2, 3 Policastro P....Boime I. (1983)
    2. Chorionic gonadotropin has a recent origin within primates and an evolutionary history of selection. (PubMed id 11861891)1, 2, 9 Maston G.A. and Ruvolo M. (2002)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Crystal structure of human chorionic gonadotropin. (PubMed id 8202136)1, 2 Lapthorn A.J.... Isaacs N.W. (1994)
    6. Site-specific N-glycosylation of human chorionic gonadotrophin -- structural analysis of glycopeptides by one- and two-dimensional 1H NMR spectroscopy. (PubMed id 1820200)1, 2 Weisshaar G.... Renwick A.G.C. (1991)
    7. Role of disulfide bond formation in the folding of human chorionic gonadotropin beta subunit into an alpha beta dimer assembly-competent form. (PubMed id 1688430)1, 2 Saccuzo Beebe J.... Ruddon R.W. (1990)
    8. A map of the hCG beta-LH beta gene cluster. (PubMed id 2422163)1, 2 Policastro P.F.... Boime I. (1986)
    9. Evolution of the genes for the beta subunits of human chorionic gonadotropin and luteinizing hormone. (PubMed id 6690982)1, 2 Talmadge K.... Fiddes J.C. (1984)
    10. Assignment of disulfide bonds in the beta subunit of human chorionic gonadotropin. (PubMed id 7240231)1, 2 Mise T. and Bahl O.P. (1981)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 94027 HGNC: 16451 AceView: CGB_ Ensembl:ENSG00000196337 euGenes: HUgn94027
    ECgene: CGB7 H-InvDB: CGB7

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CGB7 Pharmacogenomics, SNPs, Pathways
    Wikipedia http://en.wikipedia.org/wiki/Human_chorionic_gonadotropin

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CGB7 gene:
    Search GeneIP for patents involving CGB7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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