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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

CGB5 Gene

protein-coding GIFtS: 52
GCID: GC19P049547

chorionic gonadotropin, beta polypeptide 5

Explore 129 diseases affiliated with
CGB5 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Chorionic Gonadotropin, Beta Polypeptide 5¹ ²
HCG¹ ²
Chorionic Gonadotropin Beta 5 Subunit²
CG-Beta¹
CGB3³
Chorionic Gonadotrophin Chain Beta³

External Ids:	HGNC: 16452¹	Entrez Gene: 93659²	Ensembl: ENSG00000189052⁷	OMIM: 608825⁵	UniProtKB: P01233³

Export aliases for CGB5 gene to outside databases

Previous GC identifers: GC19P050194 GC19P049915 GC19P054223 GC19P054227 GC19P054238 GC19P045923

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CGB5:

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 5 subunit of chorionic

gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta

subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates

the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is

encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the

luteinizing hormone beta subunit gene. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: CGHB_HUMAN, P01233

Function: Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000019.9 NC_018930.1 NT_011109.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the CGB5 gene promoter:
NF-1 NF-1/L Pax-5 POU3F1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CGB5 promoter sequence

Search SABiosciences Chromatin IP Primers for CGB5

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CGB5

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.32 Ensembl cytogenetic band: 19q13.33 HGNC cytogenetic band: 19q13.32

CGB5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CGB5 gene location

GeneLoc information about chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19P049547: view genomic region (about GC identifiers)

Start:	49,547,063 bp from pter	End:	49,548,568 bp from pter
Size:	1,506 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CGHB_HUMAN, P01233 (See protein sequence)

Recommended Name: Choriogonadotropin subunit beta precursor

Size: 165 amino acids; 17739 Da

Subunit: Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to

thyrotropin, lutropin, follitropin and gonadotropin

Subcellular location: Secreted

Developmental stage: Made by the first trimester placenta

Sequence caution: Sequence=CAA25068.1; Type=Erroneous initiation; Sequence=CAA25069.1; Type=Erroneous initiation;

4 PDB 3D structures from and Proteopedia for CGB5:

1HCN (3D)

1HRP (3D)

1QFW (3D)

1XUL (3D)

Secondary accessions: A1A5E0 B9ZVP5 Q13991 Q14000 Q3KPI3 Q3SY41 Q8WTT5 Q8WXL1 Q8WXL2 Q8WXL3 Q8WXL4

Alternative splicing: 2 isoforms: P01233-1 P01233-2 (Ref.2 (CAA25069) sequence is in conflict in positions: 7:G->R, 9:A->V, 12:D->G)

Explore the universe of human proteins at neXtProt for CGB5: NX_P01233

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_P01233

CGB5 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_149032.1

ENSEMBL proteins:

ENSP00000301408

Reactome Protein details: P01233
Human Recombinant Protein Products for CGB5:

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Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	--	--
GO:0005625	soluble fraction	--	--

CGB5 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

CGB5 for domains About GeneDecksing

3 InterPro domains/families:

IPR018245 Gonadotropin_bsu_CS

IPR001545 Gonadotropin_bsu

IPR006208 Cys_knot

Graphical View of Domain Structure for InterPro Entry P01233

ProtoNet protein and cluster: P01233

3 Blocks protein families:

IPB001545 Gonadotropin

IPB002400 Growth factor cystine knot superfamily signature

IPB006208 Cystine knot domain

UniProtKB/Swiss-Prot: CGHB_HUMAN, P01233

Similarity: Belongs to the glycoprotein hormones subunit beta family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: CGHB_HUMAN, P01233

Function: Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005179	hormone activity	--	--

CGB5 for ontologies About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for CGB5

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In Situ Assay
Products:

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for CGB5

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Pathway sources
See GeneCards unified pathways
Show all pathways

4 Reactome Pathways for CGB5

	Peptide hormone biosynthesis
	Metabolism of proteins
	Glycoprotein hormones
	Peptide hormone metabolism

CGB5 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for CGB5

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

5 Interacting proteins for CGB5 (P01233^{2, 3} ENSP00000301408⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CGA	P01215²^,³, ENSP00000358595⁴	MINT-24926 I2D: score=5 STRING: ENSP00000358595
CKB	P12277³	I2D: score=1
EWSR1	Q01844³	I2D: score=1
FSHB	P01225³	I2D: score=1
LHCGR	P22888³	I2D: score=1

About this table

Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006915	apoptotic process	--	--
GO:0007165	signal transduction	--	--
GO:0007267	cell-cell signaling	--	--
GO:0007292	female gamete generation	--	--
GO:0016486	peptide hormone processing	--	--

CGB5 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

CGB5 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CGB5
UniProtKB/Swiss-Prot: CGHB_HUMAN, P01233

Pharmaceutical: Available under the names Novarel (Ferring) and Profasi (Serono). Used as adjunctive therapy in the

treatment of obesity. There is no substantial evidence that it increases weight loss beyond that resulting from

caloric restriction, that it causes a more attractive or 'normal' distribution of fat, or that it decreases the hunger

and discomfort associated with calorie-restricted diets

10/140 Novoseek chemical compound relationships for CGB5 gene (see all 140) About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
progesterone	79.4	499	18070493 (6), 20503230 (6), 7629236 (6), 8147233 (5) (see all 99)
testosterone	73.2	344	7629236 (6), 17477304 (5), 12220777 (5), 12538621 (4) (see all 99)
gnrh	72.2	267	7852524 (10), 8114013 (7), 7951519 (6), 1517367 (6) (see all 84)
estradiol	69.8	139	18413150 (4), 19191722 (4), 2117066 (3), 1479151 (3) (see all 78)
b 152	65.9	6	17092638 (3)
methotrexate	61.7	82	16313819 (4), 11919242 (4), 17173905 (4), 9302177 (4) (see all 36)
3beta-hydroxysteroid	60.1	7	19501915 (1), 2149342 (1), 8187962 (1), 8964869 (1) (see all 7)
11-ketotestosterone	58.6	23	12714013 (2), 9771643 (2), 15965976 (2), 9493828 (1) (see all 9)
17-hydroxyprogesterone	57.6	14	9593605 (3), 1577246 (2), 9363253 (1), 10599984 (1) (see all 9)
22r-hydroxycholesterol	57	6	17431488 (1), 19330017 (1), 7556884 (1), 10613393 (1)

Search CenterWatch for drugs/clinical trials and news about CGB5 / CGHB

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CGB5 gene:

NM_033043.1

Unigene Cluster for CGB5:

Chorionic gonadotropin, beta polypeptide 5

Hs.172944 [show with all ESTs]

Unigene Representative Sequence: BM916725

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000301408(uc002ply.3)

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Additional cDNA sequence:

BC006290.2 BC051378.1 BC103970.1 BC103971.1 BC106723.1 BC106724.1 BT006890.1 K03180.1

5 DOTS entries:

DT.119691 DT.97797965 DT.100837633 DT.92436853 DT.95315378

24/247 AceView cDNA sequences (see all 247):

BC069367 AA330859 NM_033378 BC051378 AA331012 CA944648 NM_033043 BC006290

T50278 CR616977 N29831 BF589174 CF528171 BQ004041 BQ007244 N40038

CF527786 AI160936 BV195545 N32108 BC069526 BU752736 AU139360 BX336252

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CGB5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

CGB5 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

GABA neuron-like cells (Generation of motor ...)

Brain

Syncytiotrophoblast-like cells (Generation of syncyt...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See CGB5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CGB5

SOURCE GeneReport for Unigene cluster: Hs.172944

UniProtKB/Swiss-Prot: CGHB_HUMAN, P01233

Tissue specificity: Placenta

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In Situ
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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for CGB5 gene from 2/6 species (see all 6) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
lizard (Anolis carolinensis)	Reptilia	--	--	37(a)	1 → many	6(80158039-80158659)
zebrafish (Danio rerio)	Actinopterygii	lhb⁶	luteinizing hormone, beta polypeptide	40(a)	1 → many	Zv9_scaffold3525(54871-57837)

ENSEMBL Gene Tree for CGB5 (if available)
TreeFam Gene Tree for CGB5 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for CGB5 gene

CGB8¹ ² CGB¹ ² TSHB² FSHB² CGB2² LHB² ENSG00000267335² CGB7²

CGB1²

7 SIMAP similar genes for CGB5 using alignment to 1 protein entry: CGHB_HUMAN:

CGB8 CGB2 CGB1 CGB7 LHB FSHB

TSHB

CGB5 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 19 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs182980681^1,2		--	49545169(+)	`ACAAGA/TTGGGT`	1	--	us2k¹		0	--	--	--	--
rs113177379^1,2	C	--	49545179(+)	`TGTTAC/TGCAAG`	1	--	us2k¹		1		CSA	2
rs10419739^1,2	C,F	--	49545226(+)	`GGCTTT/CCCCAT`	1	--	us2k¹		5		NA WA	10
rs140512644^1,2		--	49545262(+)	`GGGTTC/TCCAAC`	1	--	us2k¹		0	--	--	--	--
rs145893500^1,2		--	49545327(+)	`TGTCTC/TCATGT`	1	--	us2k¹		0	--	--	--	--
rs201346438^1,2		--	49545334(+)	`ATGTG-/CTCTGAG`	1	--	us2k¹		0	--	--	--	--
rs187611412^1,2		--	49545370(+)	`TCCCCC/TAGACT`	1	--	us2k¹		0	--	--	--	--
rs191776041^1,2		--	49545382(+)	`CCTCTA/GCATCC`	1	--	us2k¹		0	--	--	--	--
rs141340606^1,2		--	49545441(+)	`CTCGAA/CATTGT`	1	--	us2k¹		0	--	--	--	--
rs184320065^1,2		--	49545457(+)	`TTTCCC/TGATCC`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for CGB5 (49547063 - 49548568 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for CGB5
3 CNVs: 67577 5109 32261

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

CGB5 for disorders           About GeneDecksing

OMIM gene information: 608825    OMIM disorders: --

20/129 diseases for CGB5 (see all 129):    About MalaCards

corpus luteum cyst 5-alpha reductase deficiency neural tube defect extragonadal germ cell tumor

21-hydroxylase deficiency placental site trophoblastic tumor germ cell tumor mixed gonadal dysgenesis

gonadal dysgenesis mixed ductal-endocrine carcinoma gestational trophoblastic tumor aromatase excess syndrome

lipoid adrenal hyperplasia nonseminomatous germ cell tumor gestational trophoblastic neoplasm trophoblastic neoplasm

habitual abortion epithelioid trophoblastic tumor ovarian hyperstimulation syndrome polycystic ovary syndrome

2 diseases from the University of Copenhagen DISEASES database for CGB5:

Cryptococcosis 3-Methylcrotonyl-CoA carboxylase deficiency

10/93 Novoseek disease relationships for CGB5 gene (see all 93) About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
choriocarcinoma	92.2	222	9833611 (5), 1889509 (4), 9826481 (4), 1967025 (4) (see all 99)
trophoblastic disease	90.7	79	20116088 (6), 1710641 (3), 15346663 (3), 9833612 (3) (see all 40)
hydatidiform mole	90	108	17462723 (6), 20116088 (5), 19155902 (4), 16711513 (3) (see all 51)
gestational trophoblastic disease	89.1	78	9475142 (3), 15663134 (3), 17086808 (3), 15305826 (3) (see all 40)
trophoblastic tumor	89	19	7712876 (2), 2167776 (2), 1661266 (1), 8492514 (1) (see all 16)
trophoblastic tumor placental site	87.5	14	11972394 (1), 12748494 (1), 17701427 (1), 17086809 (1) (see all 7)
gestational trophoblastic tumor	82.6	7	19004403 (1), 12681878 (1), 18762963 (1), 7970479 (1) (see all 5)
pregnancy ectopic	81.5	90	16507931 (7), 7614131 (4), 14633876 (4), 16308901 (4) (see all 56)
ovarian hyperstimulation syndrome	76.2	13	8005301 (1), 7920947 (1), 9240261 (1), 19573290 (1) (see all 10)
hydatidiform mole invasive	74.2	4	19099349 (1), 19817556 (1)

Genetic Association Database (GAD): CGB5
Human Genome Epidemiology (HuGE) Navigator: CGB5 (4 documents)

Export disorders for CGB5 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for CGB5 gene, integrated from 9 sources (see all 1209):
(articles sorted by number of sources associating them with CGB5)

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The beta subunit of human chorionic gonadotropin is encoded by multiple genes. (PubMed id 6194155)^{1, 2, 3} Policastro P....Boime I. (1983)
Absence of the genetic variant Val79Met in human chorionic gonadotropin-beta gene 5 in five European populations. (PubMed id 15299093)^{1, 4} Jiang M....Huhtaniemi I. (2004)
Crystal structure of human chorionic gonadotropin. (PubMed id 8202136)^{1, 2} Lapthorn A.J.... Isaacs N.W. (1994)
A map of the hCG beta-LH beta gene cluster. (PubMed id 2422163)^{1, 2} Policastro P.F.... Boime I. (1986)
Evolution of the genes for the beta subunits of human chorionic gonadotropin and luteinizing hormone. (PubMed id 6690982)^{1, 2} Talmadge K.... Fiddes J.C. (1984)
The ISOBM TD-7 Workshop on hCG and related molecules. Towards user-oriented standardization of pregnancy and tumor diagnosis: assignment of epitopes to the three-dimensional structure of diagnostically and commercially relevant monoclonal antibodies directed against human chorionic gonadotropin and derivatives. (PubMed id 11893904)^{1, 9} Berger P....Stenman U.H. (2002)
Human chorionic gonadotropin (hCG) up-regulates wnt5b and wnt7b in the mammary gland, and hCGbeta transgenic female mice present with mammary Gland tumors exhibiting characteristics of the Wnt/beta-catenin pathway activation. (PubMed id 17510243)^{1, 9} Kuorelahti A....Poutanen M. (2007)
Single-chain human chorionic gonadotropin analogs containing the determinant loop of the beta-subunit linked to the alpha-subunit. (PubMed id 12914533)^{1, 9} Schubert R.L. and Puett D. (2003)
A central role for Ets-2 in the transcriptional regulation and cyclic adenosine 5'-monophosphate responsiveness of the human chorionic gonadotropin-beta subunit gene. (PubMed id 12511603)^{1, 9} Ghosh D....Roberts R.M. (2003)
Maternal body mass index and serum concentrations of h uman chorionic gonadotropin in very early pregnancy. (PubMed id 22769733)¹ Eskild A....Tanbo T.G. (2012)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
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Free Text

Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 93659	HGNC: 16452	AceView: CGB5andCGB2	Ensembl:ENSG00000189052	euGenes: HUgn93659
ECgene: CGB5	H-InvDB: CGB5

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for CGB5	Pharmacogenomics, SNPs, Pathways
Wikipedia	http://en.wikipedia.org/wiki/Human_chorionic_gonadotropin

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chorionic gonadotropin, beta polypeptide 5

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CGB5 Gene

chorionic gonadotropin, beta polypeptide 5

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