Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



CGB2 Gene

protein-coding   GIFtS: 45
GCID: GC19P049535

Chorionic Gonadotropin, Beta Polypeptide 2

  Search for CGB2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Chorionic Gonadotropin, Beta Polypeptide 21 2
Choriogonadotropin Subunit Beta Variant 22
Product Of CGB22

External Ids:    HGNC: 167221   Entrez Gene: 1143362   Ensembl: ENSG000001048187   OMIM: 6088245   UniProtKB: Q6NT523   

Export aliases for CGB2 gene to outside databases

Previous GC identifers: GC19P050193 GC19P049866 GC19P054211 GC19P054226 GC19P045911


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for CGB2 Gene:
The beta subunit of chorionic gonadotropin (CGB) is encoded by six highly homologous and structurally similar
genes that are arranged in tandem and inverted pairs on chromosome 19q13.3, and contiguous with the luteinizing
hormone beta (LHB) subunit gene. The CGB genes are primarily distinguished by differences in the 5' untranscribed
region. This gene was originally thought to be one of the two pseudogenes (CGB1 and CGB2) of CGB subunit,
however, detection of CGB1 and CGB2 transcripts in vivo, and their presence on the polysomes, suggested that
these transcripts are translated. To date, a protein product corresponding to CGB2 has not been isolated. The
deduced sequence of the hypothetical protein of 132 aa does not share any similarity with that of functional CGB
subunits (PMID:8954017). However, a 163 aa protein, translated from a different frame, is about the same size,
and shares 98% identity with other CGB subunits. (provided by RefSeq, Jul 2008)

GeneCards Summary for CGB2 Gene:
CGB2 (chorionic gonadotropin, beta polypeptide 2) is a protein-coding gene. GO annotations related to this gene include hormone activity. An important paralog of this gene is TSHB.

Gene Wiki entry for CGB2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NT_011109.17  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CGB2 gene promoter:
         Egr-3   AhR   NF-1/L   NF-1   Pax-5   GATA-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCGB2 promoter sequence
   Search Chromatin IP Primers for CGB2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CGB2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.32   Ensembl cytogenetic band:  19q13.33   HGNC cytogenetic band: 19q13.32

CGB2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CGB2 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P049535:  view genomic region     (about GC identifiers)

Start:
49,535,130 bp from pter      End:
49,536,495 bp from pter
Size:
1,366 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: CGB2_HUMAN, Q6NT52 (See protein sequence)
Recommended Name: Choriogonadotropin subunit beta variant 2 precursor  
Size: 195 amino acids; 21221 Da
Secondary accessions: B9ZVM5
Alternative splicing: 2 isoforms:  Q6NT52-1   Q6NT52-2   (Does not have any homology with the functional beta-subunit. This change has been caused by an inserted DNA fragment within the 5'-UTR of CGB2 providing a novel exon 1 as well as a 1 bp shifted ORF for exons 2 and 3)

Explore the universe of human proteins at neXtProt for CGB2: NX_Q6NT52

Explore proteomics data for CGB2 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn63, Asn80

  • See CGB2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_203696.2  
    ENSEMBL proteins: 
     ENSP00000471177   ENSP00000352295  

    CGB2 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for CGB2
    GenScript Custom Purified and Recombinant Proteins Services for CGB2
    Novus Biologicals CGB2 Proteins
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for CGB2 

    CGB2 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for CGB2
    Novus Biologicals CGB2 Antibodies
    Search for Antibodies for CGB2 at Abcam
    Browse Antibodies at Cloud-Clone Corp.
    ThermoFisher Antibodies for CGB2
    LSBio Antibodies in human, mouse, rat for CGB2

    CGB2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CGB2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CGB2
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for CGB2 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    3 InterPro protein domains:
     IPR018245 Gonadotropin_bsu_CS
     IPR001545 Gonadotropin_bsu
     IPR006208 Cys_knot

    Graphical View of Domain Structure for InterPro Entry Q6NT52

    ProtoNet protein and cluster: Q6NT52

    1 Blocks protein domain: IPB002400 Growth factor cystine knot superfamily signature

    UniProtKB/Swiss-Prot: CGB2_HUMAN, Q6NT52
    Similarity: Belongs to the glycoprotein hormones subunit beta family


    Find genes that share domains with CGB2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005179hormone activity IEA--
         
    Find genes that share ontologies with CGB2           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CGB2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CGB2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CGB2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CGB2

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat CGB2 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate CGB2
    SwitchGear 3'UTR luciferase reporter plasmidCGB2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CGB2
    Predesigned siRNA for gene silencing in human, mouse, rat CGB2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CGB2

    Clone
    Products:
         
    OriGene clones in human, mouse for CGB2 (see all 4)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CGB2 (NM_002407)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CGB2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CGB2

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for CGB2
    Browse ESI BIO Cell Lines and PureStem Progenitors for CGB2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CGB2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    CGB2_HUMAN, Q6NT52: Secreted
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    cytosol3

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--

    Find genes that share ontologies with CGB2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CGB2
    Interactions:

        Search GeneGlobe Interaction Network for CGB2

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for CGB2 (ENSP000003522954) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NR5A1ENSP000003626904STRING: ENSP00000362690
    NR5A2ENSP000003563314STRING: ENSP00000356331
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CGB2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for CGB2 gene: 
    NM_033378.1  

    Unigene Cluster for CGB2:

    Chorionic gonadotropin, beta polypeptide 2
    Hs.567650  [show with all ESTs]
    Unigene Representative Sequence: BC107143
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000474913(uc010yaf.2) ENST00000359342(uc002plw.3)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CGB2 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate CGB2
    SwitchGear 3'UTR luciferase reporter plasmidCGB2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CGB2
    Predesigned siRNA for gene silencing in human, mouse, rat CGB2
    Clone
    Products:
         
    OriGene clones in human, mouse for CGB2 (see all 4)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CGB2 (NM_002407)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CGB2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CGB2
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for CGB2
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat CGB2
      QuantiTect SYBR Green Assays in human, mouse, rat CGB2
      QuantiFast Probe-based Assays in human, mouse, rat CGB2

    Additional mRNA sequence: 

    BC069367.1 BC107143.1 

    4 DOTS entries:

    DT.100044715  DT.121475007  DT.100837633  DT.97797965 

    Selected AceView cDNA sequences (see all 247):

    NM_033043 BC069367 CA944648 NM_033378 T50278 AA330859 AA331012 BC006290 
    BC051378 BQ004068 BQ003981 BE732062 BC069526 BQ007244 AA330413 BQ011267 
    AI160579 CF530089 AA330717 BF589174 AI189842 BE901661 AU139360 CF528171 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    CGB2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    CGB2 Expression
    About this image


    CGB2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
    CGB2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CGB2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.567650

    UniProtKB/Swiss-Prot: CGB2_HUMAN, Q6NT52
    Tissue specificity: Expressed in placenta, testis and pituitary

        Custom PCR Arrays for CGB2
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for CGB2
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat CGB2
    QuantiTect SYBR Green Assays in human, mouse, rat CGB2
    QuantiFast Probe-based Assays in human, mouse, rat CGB2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CGB2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for CGB2 gene from Selected species (see all 6)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    37(a)
    1 → many
    6(80158039-80158659)
    zebrafish
    (Danio rerio)
    Actinopterygii lhb6
    luteinizing hormone, beta polypeptide
    39(a)
    1 → many
    Zv9_scaffold3525(54871-57837) ENSDARG00000035709
            Species with no ortholog for CGB2

    ENSEMBL Gene Tree for CGB2 (if available)
    TreeFam Gene Tree for CGB2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for CGB2 gene
    CGB11 2  TSHB2  FSHB2  LHB2  CGB82  ENSG000002673352  CGB52  CGB2  
    CGB72  
    8 SIMAP similar genes for CGB2 using alignment to 3 protein entries:     CGB2_HUMAN (see all proteins):
    CGB    CGB5    CGB8    CGB7    CGB1    LHB
    FSHB    TSHB

    Find genes that share paralogs with CGB2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for CGB2 (see all 26)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs104238591,2
    C,F--49533163(+) CCTTTT/CGGGAG 1 -- us2k14Minor allele frequency- C:0.22NA WA EA 244
    rs1866066131,2
    --49533201(+) CAGCGA/TGGGGT 1 -- us2k10--------
    rs1115278381,2
    F--49533222(+) TCACCG/AGCGAG 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs1392622831,2
    --49533224(+) ACCGGC/TGAGTC 1 -- us2k10--------
    rs1809841561,2
    --49533276(+) GTGACA/GGACCC 1 -- us2k10--------
    rs104230941,2
    C,F,H--49533380(+) CACCTG/TCTTCA 1 -- us2k112Minor allele frequency- T:0.31NS EA NA WA 786
    rs1870314031,2
    C--49533402(+) TCTGAA/GGAAGG 1 -- us2k10--------
    rs1909591841,2
    --49533481(+) AGGCCA/TAGCAG 1 -- us2k10--------
    rs2013479571,2
    C--49533494(+) CTATGG/TGCGGG 1 -- us2k10--------
    rs1835021581,2
    --49533548(+) TCAAAC/TTGGCA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CGB2 (49535130 - 49536495 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for CGB2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2718698CNV Deletion23290073
    nsv833859CNV Loss17160897
    nsv912248CNV Loss21882294
    nsv833857CNV Loss17160897
    nsv912251CNV Loss21882294
    dgv3970n71CNV Loss21882294
    nsv912252CNV Loss21882294
    dgv592n67CNV Loss20364138
    esv22462CNV Gain19812545
    nsv9739CNV Gain+Loss18304495

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CGB2
    DNA2.0 Custom Variant and Variant Library Synthesis for CGB2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 608824    OMIM disorders: --


    Find genes that share disorders with CGB2           About GenesLikeMe


    Export disorders for CGB2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for CGB2 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with CGB2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The beta subunit of human chorionic gonadotropin is encoded by multiple genes. (PubMed id 6194155)1, 3 Policastro P....Boime I. (J. Biol. Chem. 1983)
    2. The evolution and genomic landscape of CGB1 and CGB2 genes. (PubMed id 17055150)1, 9 Hallast P....Laan M. (Mol. Cell. Endocrinol. 2007)
    3. Human Chorionic Gonadotropin Beta Subunit Genes CGB1 and CGB2 are Transcriptionally Active in Ovarian Cancer. (PubMed id 23774837)1 Kubiczak M....Jankowska A. (Int J Mol Sci 2013)
    4. Fine-scale quantification of HCG beta gene transcription in human trophoblastic and non-malignant non-trophoblastic tissues. (PubMed id 18048458)2 Rull K.... Laan M. (Mol. Hum. Reprod. 2008)
    5. Expression of beta-subunit of HCG genes during normal and failed pregnancy. (PubMed id 16123088)2 Rull K. and Laan M. (Hum. Reprod. 2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (Nature 2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. The sequence of the human genome. (PubMed id 11181995)1 Venter J.C.... Zhu X. (Science 2001)
    10. Expression of the human chorionic gonadotropin-beta gene cluster in human pituitaries and alternate use of exon 1. (PubMed id 8954017)1 Dirnhofer S....Berger P. (J. Clin. Endocrinol. Metab. 1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 114336 HGNC: 16722 AceView: CGB5andCGB2 Ensembl:ENSG00000104818 euGenes: HUgn114336
    ECgene: CGB2 H-InvDB: CGB2

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for CGB2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for CGB2 gene:
    Search GeneIP for patents involving CGB2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for CGB2  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for CGB2  
     OriGene qSTAR qPCR primer pairs in human, mouse for CGB2   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for CGB2   OriGene Custom Protein Services for CGB2  

     
     
     Block miRNA regulation of human, mouse, rat CGB2 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing CGB2
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CGB2 Predesigned siRNA for gene silencing in human, mouse, rat CGB2
     QuantiFast Probe-based Assays in human, mouse, rat CGB2 QuantiTect SYBR Green Assays in human, mouse, rat CGB2
     Custom PCR Arrays for CGB2 Search Chromatin IP Primers for CGB2
     Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat CGB2 Search GeneGlobe Interaction Network for CGB2
     Regulatory tfbs in CGB2 promoter
     GenScript Custom Purified and Recombinant Proteins Services for CGB2 GenScript cDNA clones with any tag delivered in your preferred vector for CGB2
     GenScript Custom Assay Services for CGB2 GenScript Custom overexpressing Cell Line Services for CGB2
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for CGB2
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     CGB2 antibodies
     CGB2 proteins
     Search for Antibodies for CGB2 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for CGB2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for CGB2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CGB2
     SwitchGear 3'UTR luciferase reporter plasmids for CGB2
     SwitchGear Promoter luciferase reporter plasmids for CGB2
     ThermoFisher Antibodies for CGB2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CGB2
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CGB2
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CGB2
     LSBio Antibodies in human, mouse, rat for CGB2
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for CGB2
      Search eBioscience for proteins for CGB2
      Search eBioscience for elisas for CGB2
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      CGB2 gene at Home site.
    Version: 3.12.212 17 Sep 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4