Aliases for CGB Gene
External Ids for CGB Gene
Previous GeneCards Identifiers for CGB Gene
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for CGB Gene
CGB (Chorionic Gonadotropin, Beta Polypeptide) is a Protein Coding gene. Diseases associated with CGB include sarcomatoid renal cell carcinoma and ectopic pregnancy. Among its related pathways are Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein and Peptide hormone metabolism. GO annotations related to this gene include hormone activity. An important paralog of this gene is TSHB.
UniProtKB/Swiss-Prot for CGB Gene
Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy