CFL2 Gene
protein-coding GIFtS: 65
GCID: GC14M035179
|
|
cofilin 2 (muscle)
| |
Aliases
for CFL2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Cofilin 2 (Muscle)1 2 | | NEM71 2 5 | | Cofilin, Muscle Isoform2 3 | | Cofilin-21 | | Nemaline Myopathy Type 72 |
| External Ids: | HGNC: 18751 | Entrez Gene: 10732 | Ensembl: ENSG000001654107 | OMIM: 6014435 | UniProtKB: Q9Y2813 |
|---|
| | ORGUL members: | |
|---|
| NONCODE:n408153 n408151 | |
Export aliases for CFL2 gene to outside databasesPrevious GC identifers: GC14M032557 GC14M028967 GC14M033169 GC14M034249 GC14M015292
Summaries
for CFL2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CFL2:
This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This proteinis a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilinto actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations inthis gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multipletranscript variants. (provided by RefSeq, Jul 2009)
UniProtKB/Swiss-Prot: COF2_HUMAN, Q9Y281Function: Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability tobind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmicactin rods (By similarity)
Gene Wiki entry for CFL2
|
Genomic Views
for CFL2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000014.8 NC_018925.1 NT_026437.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CFL2 gene promoter:
STAT5B Sox5 HNF-1 FOXO1a FOXO1 HNF-1A
Other transcription factors
Search SABiosciences Chromatin IP Primers for CFL2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CFL2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 14q12 Ensembl cytogenetic band: 14q13.1 HGNC cytogenetic band: 14q13.2CFL2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14M035179: view genomic region
(about GC identifiers)
Start:
|
35,179,588 bp from pter |
End:
|
35,184,029 bp from pter |
Size:
|
4,442 bases |
Orientation:
|
minus strand |
ORGUL member locations:
Legend (see complete legend)
 |
Proteins
for CFL2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: COF2_HUMAN, Q9Y281 (See
protein sequence)Recommended Name: Cofilin-2 Size: 166 amino acids; 18737 Da
Subcellular location: Nucleus matrix (By similarity). Cytoplasm, cytoskeleton (By similarity)Alternative splicing: 2 isoforms: Q9Y281-1 Q9Y281-2 Explore the universe of human proteins at neXtProt for CFL2: NX_Q9Y281
Post-translational modifications:
The phosphorylation of Ser-24 may prevent recognition of the nuclear localization signal1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y281
CFL2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001230574.1 NP_068733.1 NP_619579.1
ENSEMBL proteins: ENSP00000340635 ENSP00000298159 ENSP00000450862 ENSP00000409326 ENSP00000452451 ENSP00000452188
Human Recombinant Protein Products for CFL2:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
CFL2 for ontologies About GeneDecksing
CFL2 Antibody Products:
Assay Products for CFL2: |
Protein
Domains /
Families
for CFL2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CFL2 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9Y281ProtoNet protein and cluster: Q9Y281 1 Blocks protein family: IPB002108 Actin-binding
UniProtKB/Swiss-Prot: COF2_HUMAN, Q9Y281Similarity: Belongs to the actin-binding proteins ADF familySimilarity: Contains 1 ADF-H domain |
Function
for CFL2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: COF2_HUMAN, Q9Y281Function: Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability tobind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmicactin rods (By similarity) Genatlas biochemistry entry for CFL2:cofilin 2,actin-binding protein,muscle type,depolymerisation factor of F-actin to G-actin
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
CFL2 for ontologies About GeneDecksing
Phenotypes:
5 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Cfl2):
CFL2 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Cfl2tm1.1Itl for CFL2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CFL2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CFL2 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for CFL2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CFL2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CFL2 |
|
Pathways & Interactions
for CFL2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/24 super-pathways (see all 24) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cell adhesion_Integrin-mediated cell adhesion and migration | | | 2 | Immune response _CCR3 signaling in eosinophils | | | 3 | Actin Nucleation by ARP-WASP Complex | | | 4 | Cytoskeleton remodeling Slit-Robo signaling | | | 5 | Development MAG-dependent inhibition of neurite outgrowth | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/9 EMD Millipore Pathways for CFL2 (see all 9)
5/15 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CFL2 (see all 15)
5/10  GeneGo (Thomson Reuters) Pathways for CFL2 (see all 10)
4  BioSystems Pathways for CFL2
4 
Kegg Pathways (Kegg details for CFL2):
CFL2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CFL2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 18)
5/22 Interacting proteins for CFL2 (Q9Y2811, 2, 3 ENSP000002981594) via UniProtKB, MINT, STRING, and/or I2D (see all 22)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| ACTB | P607091, 2, 3, ENSP000003499604 | EBI-351218,EBI-353944 MINT-66169 I2D:
score=7 STRING: ENSP00000349960 | | MAP3K3 | Q997592, 3 | MINT-48513 I2D:
score=2 | | ACTG1 | P632611, 2, 3, ENSP000003315144 | EBI-351218,EBI-351292 MINT-66294 I2D:
score=6 STRING: ENSP00000331514 | | LIMK1 | P536673, ENSP000003367404 | I2D:
score=1 STRING: ENSP00000336740 | | SSH1 | Q8WYL53, ENSP000003157134 | I2D:
score=1 STRING: ENSP00000315713 |
About this table
|
Drugs & Compounds
for CFL2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CFL2
Search CenterWatch for drugs/clinical trials and news about CFL2 / COF2
|
Transcripts
for CFL2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CFL2 gene (3 alternative transcripts): NM_001243645.1 NM_021914.7 NM_138638.4 Unigene Cluster for CFL2: Cofilin 2 (muscle) Hs.180141 [show with all ESTs]Unigene Representative Sequence: NM_1386386 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000341223(uc001wsg.3) ENST00000298159(uc010tpn.1 uc001wsh.3 uc001wsi.3 uc001wsj.3)
ENST00000554470 ENST00000422678 ENST00000555765 ENST00000556161
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CFL2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CFL2 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): CFL2 (NM_021914) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CFL2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CFL2 |
Additional cDNA sequence: AF087867.1 AF134802.1 AF134803.1 AK314157.1 AL117457.1 BC011444.1 BC022364.1 BC022876.1 BC025683.1 NR_028130.1 NR_028131.1 18 DOTS entries: DT.92448139 DT.92448138 DT.91664511 DT.95325291 DT.95295406 DT.120760548 DT.120760545 DT.100821113 DT.100821115 DT.102830688 DT.95325323 DT.97821297 DT.100821117 DT.120760518 DT.120760534 DT.92448136 DT.95325293 DT.95342137 24/344 AceView cDNA sequences (see all 344): CA424687 BQ938277 AI127792 BM700117 AI968444 C01889 AA814981 CB157575 AA054723 BF439067 AA722466 AI140933 BM713457 BQ929931 BE503345 BU166750 BU195780 BM466961 CD515012 CA391325 BX380090 AA045707 CA424911 BU683085
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for CFL2 (see all 7) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | · | 7d | · | 7e | · | 7f | · | 7g |
|---|
|
| SP1: | | | | | | | | | - | | - | | - | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | - | | - | | - | | | | - | | - | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CFL2
|
Expression
for CFL2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CFL2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATGGCAATTT
About this image
See CFL2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CFL2
SOURCE GeneReport for Unigene cluster: Hs.180141
UniProtKB/Swiss-Prot: COF2_HUMAN, Q9Y281Tissue specificity: Isoform CFL2b is expressed predominantly in skeletal muscle and heart. Isoform CFL2a is expressedin various tissues
SABiosciences Custom PCR Arrays for CFL2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CFL2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CFL2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CFL2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CFL2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CFL2 |
Orthologs
for CFL2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CFL2 gene from 8/26 species (see all 26) About this table
ENSEMBL Gene Tree for CFL2 (if available)
TreeFam Gene Tree for CFL2 (if available) |
Paralogs
for CFL2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CFL2 gene
- DSTN2 CFL12
2 SIMAP similar genes for CFL2 using alignment to 5 protein entries: COF2_HUMAN (see all proteins):CFL1 DSTN
CFL2 for paralogs About GeneDecksing
|
Genomic Variants
for CFL2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 14 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CFL2 (35179588 - 35184029 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CFL2: --
Human Gene Mutation Database (HGMD): CFL2
Locus Specific Mutation Databases (LSDB): CFL2
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CFL2 |
|
Disorders
/ Diseases
for CFL2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CFL2 for disorders About GeneDecksing
OMIM gene information: 601443
OMIM disorders: 610687
UniProtKB/Swiss-Prot: COF2_HUMAN, Q9Y281
Defects in CFL2 are the cause of nemaline myopathy type 7 (NEM7) [MIM:610687]. A form of nemaline myopathy.Nemaline myopathies are muscular disorders characterized by muscle weakness of varying severity and onset, andabnormal thread-or rod-like structures in muscle fibers on histologic examination. Nemaline myopathy type 7 presentsat birth with hypotonia and generalized weakness. Major motor milestones are delayed, but independent ambulation isachieved
9  diseases for CFL2: About MalaCardsnemaline myopathy myopathy hypotonia pertussis
pancreatic cancer prostate cancer pancreatitis prostatitis
malaria
2 diseases from the University of Copenhagen DISEASES database for CFL2:Nemaline myopathy Distal arthrogryposis GeneTests: CFL2
Nemaline Myopathy
Export disorders for CFL2 gene to outside databases
|
Publications
for CFL2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CFL2 gene, integrated from 9 sources (see all 48):
(articles sorted by number of sources associating them with CFL2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of human muscle type cofilin (CFL2) in normal and regenerating muscle. (PubMed id 11422377)1, 2, 9 Thirion C.... Lochmuller H. (2001)
- Mapping of human non-muscle type cofilin (CFL1) to chromosome 11q13 and muscle-type cofilin (CFL2) to chromosome 14. (PubMed id 8800436)1, 3, 9 Gillett G.T.... Povey S. (1996)
- Nemaline myopathy with minicores caused by mutation of the CFL2 gene encoding the skeletal muscle actin-binding protein, cofilin-2. (PubMed id 17160903)1, 2 Agrawal P.B.... Beggs A.H. (2007)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Muscle LIM protein interacts with cofilin 2 and regul ates F-actin dynamics in cardiac and skeletal muscle. (PubMed id 19752190)1, 9 Papalouka V....Sanoudou D. (2009)
- Cofilin cross-bridges adjacent actin protomers and replaces part of the longitudinal F-actin interface. (PubMed id 16530787)1, 9 Kudryashov D.S....Reisler E. (2006)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Cofilin weakly interacts with 14-3-3 and therefore can only indirectly participate in regulation of cell motility by small heat shock protein HspB6 (Hsp20). (PubMed id 22450169)1 Sudnitsyna M.V....Gusev N.B. (2012)
|
External Searches for CFL2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CFL2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CFL2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CFL2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CFL2 | Pharmacogenomics, SNPs, Pathways | | Wikipedia | http://en.wikipedia.org/wiki/Cofilin |
|
| | |
About This Section
| Patent Information for CFL2 gene:
Search GeneIP for patents involving CFL2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CFL2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for CFL2 | | OriGene shRNA RFP for CFL2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CFL2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CFL2 | | | OriGene Protein Over-expression Lysate for CFL2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CFL2 | | OriGene 3'-UTR Clone for CFL2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CFL2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CFL2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for CFL2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CFL2 | | OriGene Custom Protein Services for CFL2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CFL2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CFL2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CFL2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CFL2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CFL2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CFL2 |
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| | | | Search Tocris compounds for CFL2 |
| |  |  |  |  | | | | | | Recombinant Protein for CFL2 |
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 | | | CFL2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CFL2 |
|  |  |  |  | | | | ThermoFisher Antibody for CFL2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CFL2 |
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GeneCards Homepage -
Last full update: 19 Mar 2013 -
Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 13 May 2013
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