Aliases for CFHR3 Gene
External Ids for CFHR3 Gene
Previous Symbols for CFHR3 Gene
The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
GeneCards Summary for CFHR3 Gene
CFHR3 (Complement Factor H-Related 3) is a Protein Coding gene. Diseases associated with CFHR3 include cfhr3 and cfhr1-related atypical hemolytic-uremic syndrome and macular degeneration, age-related, 1. Among its related pathways are Creation of C4 and C2 activators and Complement Pathway. An important paralog of this gene is F13B.
UniProtKB/Swiss-Prot for CFHR3 Gene
Might be involved in complement regulation