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CFHR2 Gene

protein-coding   GIFtS: 54
GCID: GC01P196789

Complement Factor H-Related 2

(Previous name: H factor (complement)-like 3)
(Previous symbols: HFL3, CFHL2)
  See CFHR2-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Complement Factor H-Related 21 2     H Factor-Like Protein 22 3
CFHL21 2 3 5     DDESK592 3
HFL31 2 3 5     FHR-22 3
FHR22 3 5     Complement Factor H-Related Protein 22
H Factor (Complement)-Like 31 2     Factor H-Related Gene 22
H Factor-Like 32 3     

External Ids:    HGNC: 48901   Entrez Gene: 30802   Ensembl: ENSG000000809107   OMIM: 6008895   UniProtKB: P369803   

Export aliases for CFHR2 gene to outside databases

Previous GC identifers: GC01P195179 GC01P168070


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CFHR2 Gene:
CFHR2 (complement factor H-related 2) is a protein-coding gene. Diseases associated with CFHR2 include dense deposit disease. An important paralog of this gene is CFHR4.

UniProtKB/Swiss-Prot: FHR2_HUMAN, P36980
Function: Might be involved in complement regulation. Can associate with lipoproteins and may play a role in lipid
metabolism

Gene Wiki entry for CFHR2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_004487.20  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CFHR2 gene promoter:
         MEF-2A   NF-AT4   NF-AT2   Zic1   NF-AT3   aMEF-2   NF-AT1   NF-AT   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCFHR2 promoter sequence
   Search Chromatin IP Primers for CFHR2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CFHR2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q31.3   Ensembl cytogenetic band:  1q31.3   HGNC cytogenetic band: 1q31.3

CFHR2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CFHR2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P196789:  view genomic region     (about GC identifiers)

Start:
196,788,898 bp from pter      End:
196,928,356 bp from pter
Size:
139,459 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: FHR2_HUMAN, P36980 (See protein sequence)
Recommended Name: Complement factor H-related protein 2 precursor  
Size: 270 amino acids; 30651 Da
1 PDB 3D structure from and Proteopedia for CFHR2:
3ZD1 (3D)    
Secondary accessions: Q14310 Q5T9T1
Alternative splicing: 2 isoforms:  P36980-1   P36980-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CFHR2: NX_P36980

Explore proteomics data for CFHR2 at MOPED

Post-translational modifications: 

  • N-glycosylated1
  • Glycosylation2 at Asn126
  • Modification sites at PhosphoSitePlus

  • See CFHR2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_005657.1  
    ENSEMBL proteins: 
     ENSP00000476677   ENSP00000356385   ENSP00000356391  

    CFHR2 Human Recombinant Protein Products:

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    Novus Biologicals CFHR2 Protein
    Novus Biologicals CFHR2 Lysates
    Sino Biological Recombinant Protein for CFHR2
    Sino Biological Cell Lysate for CFHR2
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    Cloud-Clone Corp. Proteins for CFHR2

     
    Search eBioscience for Proteins for CFHR2 

     
    antibodies-online proteins for CFHR2 (4 products) 

     
    Search antibodies-online for peptides for CFHR2

    CFHR2 Antibody Products:

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    antibodies-online antibodies for CFHR2 (10 products) 

    CFHR2 Assay Products:

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    Cloud-Clone Corp. ELISAs for CFHR2
    Cloud-Clone Corp. CLIAs for CFHR2
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    antibodies-online kits for CFHR2 (3 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    complement: Complement system

    1 InterPro protein domain:
     IPR000436 Sushi_SCR_CCP

    Graphical View of Domain Structure for InterPro Entry P36980

    ProtoNet protein and cluster: P36980

    1 Blocks protein domain: IPB000436 Sushi domain/SCR domain/CCP module

    UniProtKB/Swiss-Prot: FHR2_HUMAN, P36980
    Similarity: Contains 4 Sushi (CCP/SCR) domains


    Find genes that share domains with CFHR2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FHR2_HUMAN, P36980
    Function: Might be involved in complement regulation. Can associate with lipoproteins and may play a role in lipid
    metabolism

    Phenotypes:
         1 GenomeRNAi human phenotype for CFHR2:

     Decreased viability of wild-ty 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for CFHR2

    miRNA
    Products:
        
    miRTarBase miRNAs that target CFHR2:
    hsa-mir-335-5p (MIRT017504)

    Block miRNA regulation of human, mouse, rat CFHR2 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate CFHR2:
    hsa-miR-3662
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CFHR2

    Gene Editing
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    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CFHR2

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CFHR2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    FHR2_HUMAN, P36980: Secreted
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    lysosome1
    plasma membrane1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--

    Find genes that share ontologies with CFHR2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CFHR2
    Interactions:

        Search GeneGlobe Interaction Network for CFHR2

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for CFHR2 (P369803 ENSP000003563854) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATG12O948173I2D: score=1 
    SERBP1ENSP000003600344STRING: ENSP00000360034
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CFHR2 (FHR2)

    1 Novoseek inferred chemical compound relationship for CFHR2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    heparin 34.8 1 10408366 (1)



    Find genes that share compounds with CFHR2           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CFHR2 gene: 
    NM_005666.2  

    Unigene Cluster for CFHR2:

    Complement factor H-related 2
    Hs.632450  [show with all ESTs]
    Unigene Representative Sequence: BG567998
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000485647 ENST00000476712 ENST00000367415(uc001gtq.1 uc001gtr.1)
    ENST00000489703 ENST00000496448 ENST00000473386 ENST00000367421
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CFHR2 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate CFHR2:
    hsa-miR-3662
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for CFHR2
    Predesigned siRNA for gene silencing in human, mouse, rat CFHR2
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    OriGene clones in human, mouse for CFHR2 (see all 6)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CFHR2 (NM_005666)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CFHR2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CFHR2
    Primer
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    OriGene qPCR primer pairs and template standards for CFHR2
    OriGene qSTAR qPCR primer pairs in human, mouse for CFHR2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CFHR2
      QuantiTect SYBR Green Assays in human, mouse, rat CFHR2
      QuantiFast Probe-based Assays in human, mouse, rat CFHR2

    Additional mRNA sequence: 

    BC022283.1 X64877.1 

    9 DOTS entries:

    DT.452545  DT.92463750  DT.95211982  DT.100828430  DT.92463769  DT.92463783  DT.121361166  DT.92463758 
    DT.92463773 

    Selected AceView cDNA sequences (see all 74):

    AV681564 BG562869 CB123026 AX772812 AV681761 CB122245 T67925 BG617178 
    AV692340 BG563738 BG616668 BC022283 BG563564 BG568304 X64877 BG563114 
    BG563035 CB120373 BG565462 BG533248 AV688058 BG566607 AV685061 AV685632 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CFHR2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGTAATATCA
    CFHR2 Expression
    About this image

    CFHR2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CFHR2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.632450

    UniProtKB/Swiss-Prot: FHR2_HUMAN, P36980
    Tissue specificity: Expressed by the liver and secreted in plasma

        Custom PCR Arrays for CFHR2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CFHR2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for CFHR2 gene from Selected species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    oppossum
    (Monodelphis domestica)
    Mammalia --
    Uncharacterized protein
    9(a)
    1 → many
    2(96859085-96978404)
    chicken
    (Gallus gallus)
    Aves --
    Uncharacterized protein
    8(a)
    1 → many
    8(2641142-2673492)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    4(a)
    many ↔ many
    GL343440.1(798097-827033)
    zebrafish
    (Danio rerio)
    Actinopterygii cfh6
    complement factor H
    8(a)
    many ↔ many
    22(24230945-24257352) ENSDARG00000075761


    ENSEMBL Gene Tree for CFHR2 (if available)
    TreeFam Gene Tree for CFHR2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CFHR2 gene
    CFHR42  F13B2  CFHR52  CFHR32  CFH2  CFHR12  
    6 SIMAP similar genes for CFHR2 using alignment to 2 protein entries:     FHR2_HUMAN (see all proteins):
    CFHR1    CFH    CFHR5    HF    CFHR3    CFHR4

    Find genes that share paralogs with CFHR2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CFHR2 (see all 466)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1877437991,2
    C--196910954(+) TCGGAA/GAAGTG 1 -- us2k10--------
    rs94276481,2
    C,F--196911048(+) cccttG/Acactt 1 -- us2k16Minor allele frequency- A:0.45NA WA CSA 11
    rs1384635621,2
    C--196911074(+) GCCCCA/GCCCAG 1 -- us2k10--------
    rs1160809071,2
    C,F--196911083(+) AGTTTA/C/TGGCTC 1 -- us2k11WA 118
    rs1857350731,2
    C--196911100(+) CATGTG/TCTGCA 1 -- us2k10--------
    rs1927367861,2
    --196911229(+) GAGCGA/GTGACC 1 -- us2k10--------
    rs1841271301,2
    --196911258(+) GACACA/GCTCTG 1 -- us2k10--------
    rs1398011671,2
    --196911301(+) ATTTAC/TTTGCA 1 -- us2k10--------
    rs1125114571,2
    --196911341(+) ACAGAT/AAGAAA 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs1444894601,2
    --196911347(+) AGAAAG/TAAAGG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CFHR2 (196788898 - 196928356 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for CFHR2 (see all 29):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv5113CNV Deletion18987735
    nsv470770CNV Loss18288195
    dgv508n71CNV Loss21882294
    dgv500n71CNV Loss21882294
    dgv57n27CNV Loss19166990
    nsv3999CNV Loss18451855
    nsv469599CNV Loss16826518
    nsv873060CNV Loss21882294
    nsv873062CNV Gain21882294
    nsv528460CNV Gain19592680

    Human Gene Mutation Database (HGMD): CFHR2
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CFHR2
    DNA2.0 Custom Variant and Variant Library Synthesis for CFHR2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 600889    OMIM disorders: --

    1 disease for CFHR2:    
    About MalaCards
    dense deposit disease


    Find genes that share disorders with CFHR2           About GenesLikeMe

    Genetic Association Database (GAD): CFHR2
    Human Genome Epidemiology (HuGE) Navigator: CFHR2 (4 documents)

    Export disorders for CFHR2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CFHR2 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with CFHR2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The human factor H-related gene 2 (FHR2): structure and linkage to the coagulation factor XIIIb gene. (PubMed id 7672821)1, 2, 3, 9 Skerka C.... Zipfel P.F. (Immunogenetics 1995)
    2. Two additional human serum proteins structurally related to complement factor H. Evidence for a family of factor H-related genes. (PubMed id 1533657)1, 2, 3 Skerka C.... Zipfel P.E. (J. Immunol. 1992)
    3. Epidemiological approach to identifying genetic predispositions for atypical hemolytic uremic syndrome. (PubMed id 20059470)1, 4 Sullivan M....Neumann H.P. (Ann. Hum. Genet. 2010)
    4. The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration. (PubMed id 18541031)1, 4 Zhang H....Deangelis M.M. (BMC Med. Genet. 2008)
    5. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    6. Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implications. (PubMed id 17438673)1, 4 Hageman G.S....Dean M. (Ann. Med. 2006)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Complement factor H and related proteins: an expanding family of complement-regulatory proteins? (PubMed id 8172644)1, 2 Zipfel P.F. and Skerka C. (Immunol. Today 1994)
    9. Complement factor H-related hybrid protein deregulates complement in dense deposit disease. (PubMed id 24334459)1 Chen Q....Zipfel P.F. (J. Clin. Invest. 2014)
    10. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 3080 HGNC: 4890 AceView: CFHL2 Ensembl:ENSG00000080910 euGenes: HUgn3080
    ECgene: CFHR2 H-InvDB: CFHR2

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CFHR2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CFHR2 gene:
    Search GeneIP for patents involving CFHR2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
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     Antibodies for CFHR2 (Complement Factor H-related 2/CFHR2)   Browse Cell Culture Products  
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     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for CFHR2  
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     Block miRNA regulation of human, mouse, rat CFHR2 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing CFHR2
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CFHR2 Predesigned siRNA for gene silencing in human, mouse, rat CFHR2
     QuantiFast Probe-based Assays in human, mouse, rat CFHR2 QuantiTect SYBR Green Assays in human, mouse, rat CFHR2
     Custom PCR Arrays for CFHR2 Search Chromatin IP Primers for CFHR2
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CFHR2  Search GeneGlobe Interaction Network for CFHR2
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     Search Tocris compounds for CFHR2 (FHR2)
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     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
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     Proteins for CFHR2
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     Browse ESI BIO Cell Lines and PureStem Progenitors for CFHR2
     Gene Synthesis
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     Browse compounds at ApexBio
     Search Addgene for plasmids for CFHR2
      Search eBioscience for proteins for CFHR2
      Search eBioscience for elisas for CFHR2
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for CFHR2
     antibodies-online antibodies for CFHR2 (10 products)
     antibodies-online kits for CFHR2 (3 products)
      Search antibodies-online for peptides for CFHR2
     antibodies-online proteins for CFHR2 (4 products)
           
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