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Aliases for CFH Gene

Aliases for CFH Gene

  • Complement Factor H 2 3 5
  • Age-Related Maculopathy Susceptibility 1 2 3
  • H Factor 2 (Complement) 2 3
  • H Factor 1 (Complement) 2 3
  • Beta-1H 2 3
  • HF1 3 4
  • HF2 3 4
  • HF 3 4
  • Adrenomedullin Binding Protein 3
  • Beta-1-H-Globulin 3
  • Factor H-Like 1 3
  • H Factor 1 4
  • Factor H 3
  • AHUS1 3
  • AMBP1 3
  • ARMD4 3
  • ARMS1 3
  • CFHL3 3
  • FHL1 3
  • HUS 3
  • FH 3

External Ids for CFH Gene

Previous HGNC Symbols for CFH Gene

  • HF
  • HF1
  • HF2

Previous GeneCards Identifiers for CFH Gene

  • GC01P193352
  • GC01P194887
  • GC01P167862

Summaries for CFH Gene

Entrez Gene Summary for CFH Gene

  • This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011]

GeneCards Summary for CFH Gene

CFH (Complement Factor H) is a Protein Coding gene. Diseases associated with CFH include Complement Factor H Deficiency and Macular Degeneration, Age-Related, 4. Among its related pathways are Immune System and Complement Pathway. GO annotations related to this gene include heparin binding and heparan sulfate proteoglycan binding. An important paralog of this gene is CFHR5.

UniProtKB/Swiss-Prot for CFH Gene

  • Factor H functions as a cofactor in the inactivation of C3b by factor I and also increases the rate of dissociation of the C3bBb complex (C3 convertase) and the (C3b)NBB complex (C5 convertase) in the alternative complement pathway.

Gene Wiki entry for CFH Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CFH Gene

Genomics for CFH Gene

Regulatory Elements for CFH Gene

Enhancers for CFH Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F196649 1.1 Ensembl ENCODE 0.8 -0.4 -362 3.3 TBP PKNOX1 ESRRA TAF1 TBL1XR1 RAD21 YY1 ZNF316 POLR2A SCRT2 CFHR1 CFHR3 CFH KCNT2
GH01F196410 0.3 FANTOM5 1.3 -241.3 -241265 0.5 KCNT2 CFHR3 CFH GC01M196344 GC01P196522
GH01F196660 0.6 Ensembl 0.4 +9.1 9123 0.4 POLR2H CTCF ZNF654 PBX2 SMC3 REST PRDM1 RAD21 KCNT2 CFH GC01M196672
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CFH on UCSC Golden Path with GeneCards custom track

Promoters for CFH Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000288044 1422 3400 TBP STAT1 ESRRA TAF1 TBL1XR1 CHD1 RAD21 YY1 ARID1B POLR2H

Genomic Location for CFH Gene

Chromosome:
1
Start:
196,651,878 bp from pter
End:
196,747,504 bp from pter
Size:
95,627 bases
Orientation:
Plus strand

Genomic View for CFH Gene

Genes around CFH on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CFH Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CFH Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CFH Gene

Proteins for CFH Gene

  • Protein details for CFH Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P08603-CFAH_HUMAN
    Recommended name:
    Complement factor H
    Protein Accession:
    P08603
    Secondary Accessions:
    • A5PL14
    • P78435
    • Q14570
    • Q2TAZ5
    • Q38G77
    • Q5TFM3
    • Q8N708
    • Q9NU86

    Protein attributes for CFH Gene

    Size:
    1231 amino acids
    Molecular mass:
    139096 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAB41739.1; Type=Frameshift; Positions=341; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for CFH Gene

    Alternative splice isoforms for CFH Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CFH Gene

Post-translational modifications for CFH Gene

  • Glycosylation at Asn 217, Asn 529, Asn 718, Asn 802, Asn 822, Asn 882, Asn 911, Asn 1029, and Asn 1095
  • Modification sites at PhosphoSitePlus

Other Protein References for CFH Gene

No data available for DME Specific Peptides for CFH Gene

Domains & Families for CFH Gene

Gene Families for CFH Gene

Protein Domains for CFH Gene

Suggested Antigen Peptide Sequences for CFH Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P08603

UniProtKB/Swiss-Prot:

CFAH_HUMAN :
  • Contains 20 Sushi (CCP/SCR) domains.
Domain:
  • Contains 20 Sushi (CCP/SCR) domains.
genes like me logo Genes that share domains with CFH: view

Function for CFH Gene

Molecular function for CFH Gene

UniProtKB/Swiss-Prot Function:
Factor H functions as a cofactor in the inactivation of C3b by factor I and also increases the rate of dissociation of the C3bBb complex (C3 convertase) and the (C3b)NBB complex (C5 convertase) in the alternative complement pathway.

Gene Ontology (GO) - Molecular Function for CFH Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16612335
GO:0008201 heparin binding IDA 22471560
GO:0043395 heparan sulfate proteoglycan binding IDA 22471560
genes like me logo Genes that share ontologies with CFH: view
genes like me logo Genes that share phenotypes with CFH: view

Human Phenotype Ontology for CFH Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for CFH Gene

MGI Knock Outs for CFH:
  • Cfh tm1Mbo
  • Cfh tm1a(EUCOMM)Wtsi

Animal Model Products

miRNA for CFH Gene

miRTarBase miRNAs that target CFH

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for CFH Gene

Localization for CFH Gene

Subcellular locations from UniProtKB/Swiss-Prot for CFH Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CFH gene
Compartment Confidence
extracellular 5
plasma membrane 2
mitochondrion 1
nucleus 1
endoplasmic reticulum 1
cytosol 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for CFH Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA,TAS --
GO:0005615 extracellular space TAS 9312129
GO:0070062 extracellular exosome IDA 23533145
GO:0072562 blood microparticle IDA 22516433
genes like me logo Genes that share ontologies with CFH: view

Pathways & Interactions for CFH Gene

genes like me logo Genes that share pathways with CFH: view

Pathways by source for CFH Gene

1 Sino Biological pathway for CFH Gene
1 BioSystems pathway for CFH Gene
1 GeneGo (Thomson Reuters) pathway for CFH Gene

Gene Ontology (GO) - Biological Process for CFH Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006956 complement activation TAS 9312129
GO:0006957 complement activation, alternative pathway IEA --
GO:0030449 regulation of complement activation TAS --
GO:0045087 innate immune response IEA --
genes like me logo Genes that share ontologies with CFH: view

No data available for SIGNOR curated interactions for CFH Gene

Drugs & Compounds for CFH Gene

(19) Drugs for CFH Gene - From: PharmGKB and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Bevacizumab Approved, Investigational Pharma VEGF antagonist, Therapeutic Antibodies, Vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) inhibitors 1968
Ranibizumab Approved Pharma 474
photodynamic therapy Pharma 0

(7) Additional Compounds for CFH Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with CFH: view

Transcripts for CFH Gene

Unigene Clusters for CFH Gene

Complement factor H:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CFH Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18
SP1: -
SP2: - -
SP3: - - -
SP4:
SP5:
SP6:

Relevant External Links for CFH Gene

GeneLoc Exon Structure for
CFH
ECgene alternative splicing isoforms for
CFH

Expression for CFH Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CFH Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CFH Gene

This gene is overexpressed in Liver (x13.1) and Heart - Atrial Appendage (x4.8).

Protein differential expression in normal tissues from HIPED for CFH Gene

This gene is overexpressed in Serum (15.5), Plasma (15.3), Synovial fluid (14.8), and Monocytes (9.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for CFH Gene



Protein tissue co-expression partners for CFH Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of CFH Gene:

CFH

SOURCE GeneReport for Unigene cluster for CFH Gene:

Hs.363396

mRNA Expression by UniProt/SwissProt for CFH Gene:

P08603-CFAH_HUMAN
Tissue specificity: Expressed by the liver and secreted in plasma.
genes like me logo Genes that share expression patterns with CFH: view

Orthologs for CFH Gene

This gene was present in the common ancestor of animals.

Orthologs for CFH Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CFH 34 35
  • 98.62 (n)
dog
(Canis familiaris)
Mammalia LOC478952 34
  • 75.55 (n)
-- 35
  • 59 (a)
ManyToMany
-- 35
  • 59 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia CFH 34 35
  • 75.2 (n)
-- 35
  • 62 (a)
ManyToMany
-- 35
  • 60 (a)
ManyToMany
-- 35
  • 55 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia Cfh 34
  • 73.32 (n)
mouse
(Mus musculus)
Mammalia Cfh 34 16 35
  • 72.46 (n)
Cfhr3 35
  • 69 (a)
ManyToMany
Gm4788 35
  • 57 (a)
ManyToMany
Cfhr2 35
  • 55 (a)
ManyToMany
Cfhr1 35
  • 47 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 47 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 26 (a)
ManyToMany
chicken
(Gallus gallus)
Aves CFH 34
  • 54.61 (n)
-- 35
  • 34 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 36 (a)
ManyToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101731666 34
  • 48.21 (n)
zebrafish
(Danio rerio)
Actinopterygii LOC100535929 34
  • 49.05 (n)
cfhl3 35
  • 28 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea F36H2.5 34
  • 42.28 (n)
Species where no ortholog for CFH was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CFH Gene

ENSEMBL:
Gene Tree for CFH (if available)
TreeFam:
Gene Tree for CFH (if available)

Paralogs for CFH Gene

(6) SIMAP similar genes for CFH Gene using alignment to 4 proteins:

Pseudogenes.org Pseudogenes for CFH Gene

genes like me logo Genes that share paralogs with CFH: view

Variants for CFH Gene

Sequence variations from dbSNP and Humsavar for CFH Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs145975787 Hemolytic uremic syndrome atypical 1 (AHUS1) [MIM:235400] 196,740,703(+) AGTTA(C/T)GTACA nc-transcript-variant, reference, missense
rs149474608 Hemolytic uremic syndrome atypical 1 (AHUS1) [MIM:235400] 196,740,686(+) TATCA(G/T)TATGG nc-transcript-variant, reference, missense
rs460184 Hemolytic uremic syndrome atypical 1 (AHUS1) [MIM:235400], Pathogenic 196,747,207(-) ATTCA(A/G)CTGAT nc-transcript-variant, reference, missense
rs460897 Hemolytic uremic syndrome atypical 1 (AHUS1) [MIM:235400], other 196,747,189(-) TTCTC(A/G)AATAA nc-transcript-variant, reference, missense
VAR_019405 Complement factor H deficiency (CFHD) [MIM:609814]

Structural Variations from Database of Genomic Variants (DGV) for CFH Gene

Variant ID Type Subtype PubMed ID
nsv946555 CNV duplication 23825009
nsv8691 CNV gain+loss 18304495
nsv826008 CNV loss 20364138
nsv825997 CNV loss 20364138
nsv819563 CNV gain 19587683
nsv818744 CNV gain 17921354
nsv818733 CNV gain 17921354
nsv548755 CNV loss 21841781
nsv548754 CNV loss 21841781
nsv548749 CNV loss 21841781
nsv548748 CNV gain 21841781
nsv548747 CNV gain 21841781
nsv548746 CNV loss 21841781
nsv548745 CNV gain 21841781
nsv548744 CNV loss 21841781
nsv548743 CNV loss 21841781
nsv528460 CNV gain 19592680
nsv517662 CNV gain+loss 19592680
nsv477921 CNV novel sequence insertion 20440878
nsv471614 CNV gain+loss 15918152
nsv471393 CNV gain 19718026
nsv469810 CNV loss 16826518
nsv428290 CNV gain+loss 18775914
nsv1159821 CNV deletion 26073780
nsv1010268 CNV gain 25217958
nsv1003733 CNV gain+loss 25217958
esv3891026 CNV gain+loss 25118596
esv3588468 CNV loss 21293372
esv3588467 CNV loss 21293372
esv3584613 CNV loss 24956385
esv3578358 CNV loss 25503493
esv2758990 CNV gain+loss 17122850
esv26552 CNV gain+loss 19812545
esv1247490 CNV insertion 17803354
esv1001500 CNV deletion 20482838
dgv86e199 CNV deletion 23128226
dgv736n54 CNV loss 21841781
dgv735n54 CNV loss 21841781
dgv734n54 CNV loss 21841781
dgv733n54 CNV loss 21841781
dgv512n100 CNV loss 25217958
dgv511n100 CNV gain 25217958
dgv510n100 CNV gain+loss 25217958
dgv509n100 CNV gain+loss 25217958
dgv508n100 CNV loss 25217958
dgv507n100 CNV loss 25217958
dgv506n100 CNV gain 25217958
dgv505n100 CNV gain 25217958
dgv504n100 CNV gain 25217958
dgv503n100 CNV gain 25217958
dgv42e201 CNV deletion 23290073
dgv133e212 CNV loss 25503493
dgv132e212 CNV loss 25503493

Variation tolerance for CFH Gene

Residual Variation Intolerance Score: 39% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.10; 75.45% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CFH Gene

Human Gene Mutation Database (HGMD)
CFH
SNPedia medical, phenotypic, and genealogical associations of SNPs for
CFH

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CFH Gene

Disorders for CFH Gene

MalaCards: The human disease database

(39) MalaCards diseases for CFH Gene - From: OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
complement factor h deficiency
  • immunodeficiency with factor h anomaly
macular degeneration, age-related, 4
  • age related macular degeneration 4
hemolytic uremic syndrome, atypical 1
  • hemolytic uremic syndrome, atypical
basal laminar drusen
  • cuticular drusen
atypical hemolytic-uremic syndrome with h factor anomaly
  • atypical hus with h factor anomaly
- elite association - COSMIC cancer census association via MalaCards
Search CFH in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

CFAH_HUMAN
  • Basal laminar drusen (BLD) [MIM:126700]: Drusen are extracellular deposits that accumulate below the retinal pigment epithelium on Bruch membrane. Basal laminar drusen refers to an early adult-onset drusen phenotype that shows a pattern of uniform small, slightly raised yellow subretinal nodules randomly scattered in the macula. In later stages, these drusen often become more numerous, with clustered groups of drusen scattered throughout the retina. In time these small basal laminar drusen may expand and ultimately lead to a serous pigment epithelial detachment of the macula that may result in vision loss. {ECO:0000269 PubMed:18252232}. Note=The gene represented in this entry is involved in disease pathogenesis.
  • Complement factor H deficiency (CFHD) [MIM:609814]: A disorder that can manifest as several different phenotypes, including asymptomatic, recurrent bacterial infections, and renal failure. Laboratory features usually include decreased serum levels of factor H, complement component C3, and a decrease in other terminal complement components, indicating activation of the alternative complement pathway. It is associated with a number of renal diseases with variable clinical presentation and progression, including membranoproliferative glomerulonephritis and atypical hemolytic uremic syndrome. {ECO:0000269 PubMed:10803850, ECO:0000269 PubMed:11158219, ECO:0000269 PubMed:11170895, ECO:0000269 PubMed:11170896, ECO:0000269 PubMed:12020532, ECO:0000269 PubMed:14978182, ECO:0000269 PubMed:16612335, ECO:0000269 PubMed:9312129}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Hemolytic uremic syndrome atypical 1 (AHUS1) [MIM:235400]: An atypical form of hemolytic uremic syndrome. It is a complex genetic disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, renal failure and absence of episodes of enterocolitis and diarrhea. In contrast to typical hemolytic uremic syndrome, atypical forms have a poorer prognosis, with higher death rates and frequent progression to end-stage renal disease. {ECO:0000269 PubMed:10577907, ECO:0000269 PubMed:10762557, ECO:0000269 PubMed:11851332, ECO:0000269 PubMed:12960213, ECO:0000269 PubMed:14583443, ECO:0000269 PubMed:14978182, ECO:0000269 PubMed:20513133, ECO:0000269 PubMed:9551389}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry. Other genes may play a role in modifying the phenotype.
  • Macular degeneration, age-related, 4 (ARMD4) [MIM:610698]: A form of age-related macular degeneration, a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane. {ECO:0000269 PubMed:22019782}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.

Relevant External Links for CFH

Genetic Association Database (GAD)
CFH
Human Genome Epidemiology (HuGE) Navigator
CFH
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CFH
genes like me logo Genes that share disorders with CFH: view

No data available for Genatlas for CFH Gene

Publications for CFH Gene

  1. Complement factor H polymorphism in age-related macular degeneration. (PMID: 15761122) Klein R.J. … Hoh J. (Science 2005) 3 4 22 46 64
  2. Complement factor H mutations and gene polymorphisms in haemolytic uraemic syndrome: the C-257T, the A2089G and the G2881T polymorphisms are strongly associated with the disease. (PMID: 14583443) Caprioli J. … Noris M. (Hum. Mol. Genet. 2003) 3 4 22 46 64
  3. Complement factor H gene mutation associated with autosomal recessive atypical hemolytic uremic syndrome. (PMID: 10577907) Ying L. … Landau D. (Am. J. Hum. Genet. 1999) 3 4 22 46 64
  4. Mutations in alternative pathway complement proteins in American patients with atypical hemolytic uremic syndrome. (PMID: 20513133) Maga T.K. … Smith R.J.H. (Hum. Mutat. 2010) 3 4 46 64
  5. The dot-and-fleck retinopathy of X linked Alport syndrome is independent of complement factor H (CFH) gene polymorphisms. (PMID: 19019939) Liu J. … Savige J. (Br J Ophthalmol 2009) 3 22 46 64

Products for CFH Gene

Sources for CFH Gene

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