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Aliases for CFDP1 Gene

Aliases for CFDP1 Gene

  • Craniofacial Development Protein 1 2 3
  • BCNT 3 4 6
  • Centromere Protein 29 2 3
  • CENP-29 3 4
  • CP27 3 6
  • Phosphoprotein (Bucentaur) 3
  • Bucentaur 2
  • SWC5 3
  • Yeti 3
  • P97 3

External Ids for CFDP1 Gene

Previous GeneCards Identifiers for CFDP1 Gene

  • GC16M066257
  • GC16M076288
  • GC16M075066
  • GC16M075107
  • GC16M073885
  • GC16M061078

Summaries for CFDP1 Gene

GeneCards Summary for CFDP1 Gene

CFDP1 (Craniofacial Development Protein 1) is a Protein Coding gene.

UniProtKB/Swiss-Prot for CFDP1 Gene

  • May play a role during embryogenesis.

Gene Wiki entry for CFDP1 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CFDP1 Gene

Genomics for CFDP1 Gene

Regulatory Elements for CFDP1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for CFDP1 Gene

75,293,698 bp from pter
75,433,489 bp from pter
139,792 bases
Minus strand

Genomic View for CFDP1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CFDP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CFDP1 Gene

Proteins for CFDP1 Gene

  • Protein details for CFDP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Craniofacial development protein 1
    Protein Accession:
    Secondary Accessions:
    • O00393
    • O00404
    • Q9UEF0
    • Q9UEF1
    • Q9UEF8

    Protein attributes for CFDP1 Gene

    299 amino acids
    Molecular mass:
    33593 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CFDP1 Gene


neXtProt entry for CFDP1 Gene

Proteomics data for CFDP1 Gene at MOPED

Post-translational modifications for CFDP1 Gene

Other Protein References for CFDP1 Gene

No data available for DME Specific Peptides for CFDP1 Gene

Domains for CFDP1 Gene

Protein Domains for CFDP1 Gene


Suggested Antigen Peptide Sequences for CFDP1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 BCNT-C domain.
  • Contains 1 BCNT-C domain.
genes like me logo Genes that share domains with CFDP1: view

No data available for Gene Families for CFDP1 Gene

Function for CFDP1 Gene

Molecular function for CFDP1 Gene

GENATLAS Biochemistry:
craniofacial development protein 1,predominantly expressed in brain and moderatly in heart,liver and lung,teeth,salivary gland and periosteum of developing bones,homolog to mouse Cp27 and bovine BCNT
UniProtKB/Swiss-Prot Function:
May play a role during embryogenesis.

Gene Ontology (GO) - Molecular Function for CFDP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with CFDP1: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CFDP1

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CFDP1 Gene

Localization for CFDP1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CFDP1 Gene

Chromosome, centromere, kinetochore.

Subcellular locations from

Jensen Localization Image for CFDP1 Gene COMPARTMENTS Subcellular localization image for CFDP1 gene
Compartment Confidence
nucleus 3
cytoskeleton 1
cytosol 1

Gene Ontology (GO) - Cellular Components for CFDP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000777 condensed chromosome kinetochore IEA --
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with CFDP1: view

Pathways for CFDP1 Gene

SuperPathways for CFDP1 Gene

No Data Available

PCR Array Products

  • Pathway & Disease-focused RT² Profiler PCR Arrays

Gene Ontology (GO) - Biological Process for CFDP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007155 cell adhesion IEA --
GO:0007275 multicellular organismal development IEA --
GO:0008150 biological_process ND --
GO:0008360 regulation of cell shape IEA --
GO:0042127 regulation of cell proliferation IEA --
genes like me logo Genes that share ontologies with CFDP1: view

No data available for Pathways by source for CFDP1 Gene

Transcripts for CFDP1 Gene

Unigene Clusters for CFDP1 Gene

Craniofacial development protein 1:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CFDP1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CFDP1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b · 11c
SP1: - - - - -
SP2: -
SP5: -
SP6: - -

Relevant External Links for CFDP1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CFDP1 Gene

mRNA expression in normal human tissues for CFDP1 Gene

Protein differential expression in normal tissues for CFDP1 Gene

This gene is overexpressed in Lung (15.2), Fetal Brain (14.0), and Peripheral blood mononuclear cells (12.6).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for CFDP1 Gene

SOURCE GeneReport for Unigene cluster for CFDP1 Gene Hs.461361

mRNA Expression by UniProt/SwissProt for CFDP1 Gene

Tissue specificity: Ubiquitous.
genes like me logo Genes that share expressions with CFDP1: view

Expression partners for CFDP1 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for CFDP1 Gene

Orthologs for CFDP1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for CFDP1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CFDP1 35
  • 89.23 (n)
  • 89.9 (a)
CFDP1 36
  • 92 (a)
(Canis familiaris)
Mammalia CFDP1 35
  • 91.86 (n)
  • 93.65 (a)
P97 36
  • 94 (a)
(Mus musculus)
Mammalia Cfdp1 35
  • 83.39 (n)
  • 81.69 (a)
Cfdp1 16
Cfdp1 36
  • 84 (a)
(Pan troglodytes)
Mammalia CFDP1 35
  • 99.78 (n)
  • 99.67 (a)
CFDP1 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Cfdp1 35
  • 84.63 (n)
  • 83.05 (a)
(Monodelphis domestica)
Mammalia CFDP1 36
  • 72 (a)
(Ornithorhynchus anatinus)
Mammalia CFDP1 36
  • 46 (a)
(Gallus gallus)
Aves CFDP1 35
  • 64.41 (n)
  • 58.72 (a)
CFDP1 36
  • 59 (a)
(Anolis carolinensis)
Reptilia CFDP1 36
  • 55 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia cfdp1 35
  • 61.02 (n)
  • 57.63 (a)
Str.10816 35
(Danio rerio)
Actinopterygii Dr.29384 35
rltpr 35
  • 58.02 (n)
  • 53.58 (a)
rltpr 36
  • 49 (a)
fruit fly
(Drosophila melanogaster)
Insecta Yeti 36
  • 30 (a)
(Caenorhabditis elegans)
Secernentea F39H11.1 36
  • 26 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SWC5 36
  • 21 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.7012 36
  • 39 (a)
Species with no ortholog for CFDP1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CFDP1 Gene

Gene Tree for CFDP1 (if available)
Gene Tree for CFDP1 (if available)

Paralogs for CFDP1 Gene

No data available for Paralogs for CFDP1 Gene

Variants for CFDP1 Gene

Sequence variations from dbSNP and Humsavar for CFDP1 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs6624 -- 75,294,018(-) TTCCT(C/T)GACCG synonymous-codon, reference
rs6625 -- 75,293,802(+) TTTGT(A/G)ATTAA utr-variant-3-prime
rs166012 -- 75,397,886(+) ATACA(C/T)GACTT intron-variant
rs166013 -- 75,400,248(+) ctata(C/T)agcct intron-variant
rs173526 -- 75,426,304(+) aagat(A/C)atgac intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CFDP1 Gene

Variant ID Type Subtype PubMed ID
nsv833282 CNV Gain+Loss 17160897
nsv523405 CNV Loss 19592680
nsv833283 CNV Loss 17160897
nsv1879 CNV Insertion 18451855
esv2664082 CNV Deletion 23128226
esv2422358 CNV Duplication 17116639
esv2658846 CNV Deletion 23128226
nsv1880 CNV Insertion 18451855
nsv525232 CNV Gain 19592680
nsv525466 CNV Loss 19592680
dgv902e1 CNV Complex 17122850
esv2675348 CNV Deletion 23128226
nsv512445 CNV Loss 21212237
nsv820364 CNV Deletion 20802225
nsv827744 CNV Gain 20364138
esv2714708 CNV Deletion 23290073
dgv490n67 CNV Gain+Loss 20364138
esv991799 CNV Gain 20482838
nsv827747 CNV Loss 20364138
nsv103341 CNV Loss 16902084
esv32560 CNV Loss 17666407
nsv516019 CNV Loss 19592680
nsv521596 CNV Loss 19592680

Relevant External Links for CFDP1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CFDP1 Gene

Disorders for CFDP1 Gene

Relevant External Links for CFDP1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for CFDP1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for CFDP1 Gene

Publications for CFDP1 Gene

  1. Existence of a bovine LINE repetitive insert that appears in the cDNA of bovine protein BCNT in ruminant, but not in human, genomes. (PMID: 9602175) Takahashi I. … Iwashita S. (Gene 1998) 2 3 4 23
  2. An Alu-linked repetitive sequence corresponding to 280 amino acids is expressed in a novel bovine protein, but not in its human homologue. (PMID: 9006920) Nobukuni T. … Iwashita S. (J. Biol. Chem. 1997) 2 3 4
  3. Partial nuclear localization of a bovine phosphoprotein, BCNT, that includes a region derived from a LINE repetitive sequence in Ruminantia. (PMID: 10350657) Iwashita S. … Hashimoto K. (Biochim. Biophys. Acta 1999) 3 4
  4. CP27 function is necessary for cell survival and differentiation during tooth morphogenesis in organ culture. (PMID: 11992732) Diekwisch T.G. … Luan X. (Gene 2002) 2 3
  5. Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. (PMID: 21946350) Soler Artigas M. … Tobin M.D. (Nat. Genet. 2011) 3 48

Products for CFDP1 Gene

Sources for CFDP1 Gene

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