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Aliases for CFAP99 Gene

Aliases for CFAP99 Gene

  • Cilia And Flagella Associated Protein 99 2 3 5

External Ids for CFAP99 Gene

Summaries for CFAP99 Gene

GeneCards Summary for CFAP99 Gene

CFAP99 (Cilia And Flagella Associated Protein 99) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CFAP99 Gene

Genomics for CFAP99 Gene

Regulatory Elements for CFAP99 Gene

Enhancers for CFAP99 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04G002361 1.2 FANTOM5 ENCODE 11.7 -55.4 -55443 4.5 ATF1 PKNOX1 CREB3L1 AGO1 YY1 KDM4B ZNF592 NFIL3 SMARCA4 HMBOX1 ZFYVE28 ENSG00000251148 MXD4 CFAP99 LOC105374353 RNF4 HAUS3 POLN NELFA C4orf48
GH04G002383 0.9 FANTOM5 dbSUPER 14.3 -35.0 -34952 0.2 NR2F1 MAX GTF2A2 RAD21 NR2F2 GLIS1 NR2C1 HNF4A NR2F6 CFAP99 ZFYVE28 ENSG00000251148 MXD4 HAUS3 POLN SH3BP2 ENSG00000250623 TNIP2 PIR52561
GH04G002382 0.8 FANTOM5 14.3 -36.0 -35955 0.3 HDAC1 CTCF TBP CDC5L RAD21 FOSL1 ZNF766 POLR2A FOXK2 EGR1 ZFYVE28 CFAP99 ENSG00000251148 MXD4 HAUS3 POLN ENSG00000250623 SH3BP2 TNIP2 PIR52561
GH04G002391 0.8 Ensembl dbSUPER 13.1 -27.6 -27593 0.2 ZNF341 ZNF600 ZBTB33 MLLT1 CFAP99 ZFYVE28 ENSG00000251148 MXD4 RNF4 LOC105374353 PIR44270 PIR52561
GH04G002411 2 FANTOM5 Ensembl ENCODE dbSUPER 4.9 -5.8 -5839 4.1 HDGF PKNOX1 CREB3L1 ARID4B SIN3A DMAP1 FEZF1 ZNF766 ZNF143 FOS ZFYVE28 HAUS3 RNF4 MXD4 SH3BP2 CFAP99 HTT TNIP2 GC04M002409
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CFAP99 on UCSC Golden Path with GeneCards custom track

Genomic Location for CFAP99 Gene

Chromosome:
4
Start:
2,418,893 bp from pter
End:
2,462,963 bp from pter
Size:
44,071 bases
Orientation:
Plus strand

Genomic View for CFAP99 Gene

Genes around CFAP99 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CFAP99 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CFAP99 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CFAP99 Gene

Proteins for CFAP99 Gene

  • Protein details for CFAP99 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    D6REC4-CFA99_HUMAN
    Recommended name:
    Cilia- and flagella-associated protein 99
    Protein Accession:
    D6REC4

    Protein attributes for CFAP99 Gene

    Size:
    459 amino acids
    Molecular mass:
    52293 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CFAP99 Gene

Post-translational modifications for CFAP99 Gene

No Post-translational modifications

Other Protein References for CFAP99 Gene

No data available for DME Specific Peptides for CFAP99 Gene

Domains & Families for CFAP99 Gene

Protein Domains for CFAP99 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

D6REC4

UniProtKB/Swiss-Prot:

CFA99_HUMAN :
  • Belongs to the CFAP99 family.
Family:
  • Belongs to the CFAP99 family.
genes like me logo Genes that share domains with CFAP99: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for CFAP99 Gene

Function for CFAP99 Gene

Phenotypes for CFAP99 Gene

genes like me logo Genes that share phenotypes with CFAP99: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CFAP99 Gene

Localization for CFAP99 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CFAP99 Gene

Cell projection, cilium, flagellum.

Gene Ontology (GO) - Cellular Components for CFAP99 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0042995 cell projection IEA --
genes like me logo Genes that share ontologies with CFAP99: view

No data available for Subcellular locations from COMPARTMENTS for CFAP99 Gene

Pathways & Interactions for CFAP99 Gene

SuperPathways for CFAP99 Gene

No Data Available

Interacting Proteins for CFAP99 Gene

Gene Ontology (GO) - Biological Process for CFAP99 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CFAP99 Gene

Drugs & Compounds for CFAP99 Gene

No Compound Related Data Available

Transcripts for CFAP99 Gene

mRNA/cDNA for CFAP99 Gene

(2) REFSEQ mRNAs :
(10) Selected AceView cDNA sequences:
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CFAP99 Gene

No ASD Table

Relevant External Links for CFAP99 Gene

GeneLoc Exon Structure for
CFAP99
ECgene alternative splicing isoforms for
CFAP99

Expression for CFAP99 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CFAP99 Gene

Protein differential expression in normal tissues from HIPED for CFAP99 Gene

This gene is overexpressed in Fetal Brain (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CFAP99 Gene



Protein tissue co-expression partners for CFAP99 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of CFAP99 Gene:

CFAP99
genes like me logo Genes that share expression patterns with CFAP99: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CFAP99 Gene

Orthologs for CFAP99 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CFAP99 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC750504 34
  • 99.07 (n)
cow
(Bos Taurus)
Mammalia LOC100847979 34
  • 80.46 (n)
rat
(Rattus norvegicus)
Mammalia RGD1564567 34
  • 78.95 (n)
mouse
(Mus musculus)
Mammalia Gm21446 34
  • 78.69 (n)
Cfap99 16
chicken
(Gallus gallus)
Aves LOC422887 34
  • 56.72 (n)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100495334 34
  • 56.25 (n)
zebrafish
(Danio rerio)
Actinopterygii LOC100534701 34
  • 51.78 (n)
Species where no ortholog for CFAP99 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CFAP99 Gene

ENSEMBL:
Gene Tree for CFAP99 (if available)
TreeFam:
Gene Tree for CFAP99 (if available)

Paralogs for CFAP99 Gene

No data available for Paralogs for CFAP99 Gene

Variants for CFAP99 Gene

Sequence variations from dbSNP and Humsavar for CFAP99 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs1000011008 -- 2,419,669(+) GCCAG(C/G)TGCTC intron-variant, upstream-variant-2KB
rs1000059398 -- 2,462,413(+) CGGCC(G/T)GCTCC intron-variant, upstream-variant-2KB
rs1000064899 -- 2,442,481(+) CAGCA(C/G)TGACT intron-variant
rs1000081716 -- 2,429,691(+) GGTTC(A/G)CGCCA intron-variant
rs1000111453 -- 2,462,198(+) AAAAG(A/G)AAAAA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for CFAP99 Gene

Variant ID Type Subtype PubMed ID
dgv806e201 CNV deletion 23290073
dgv807e201 CNV deletion 23290073
esv1499184 CNV deletion 17803354
esv25676 CNV loss 19812545
esv2662736 CNV deletion 23128226
esv2726835 CNV deletion 23290073
esv2726846 CNV deletion 23290073
esv2726852 CNV deletion 23290073
esv275562 CNV gain+loss 21479260
esv32578 CNV loss 17666407
esv3336658 CNV duplication 20981092
esv3599402 CNV loss 21293372
esv8335 CNV gain 19470904
nsv1009347 CNV gain 25217958
nsv1010352 CNV gain 25217958
nsv1013194 CNV gain 25217958
nsv289764 CNV deletion 16902084
nsv292996 CNV deletion 16902084
nsv293699 CNV insertion 16902084
nsv518472 CNV loss 19592680
nsv593403 CNV loss 21841781
nsv593419 CNV loss 21841781

Relevant External Links for CFAP99 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CFAP99

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CFAP99 Gene

Disorders for CFAP99 Gene

Relevant External Links for CFAP99

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CFAP99

No disorders were found for CFAP99 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CFAP99 Gene

Publications for CFAP99 Gene

  1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4 64
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for CFAP99 Gene

Sources for CFAP99 Gene

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