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Aliases for CFAP77 Gene

Aliases for CFAP77 Gene

  • Cilia And Flagella Associated Protein 77 2 3 5
  • C9orf171 3 4
  • Chromosome 9 Open Reading Frame 171 2

External Ids for CFAP77 Gene

Previous HGNC Symbols for CFAP77 Gene

  • C9orf171

Previous GeneCards Identifiers for CFAP77 Gene

  • GC09P132420

Summaries for CFAP77 Gene

GeneCards Summary for CFAP77 Gene

CFAP77 (Cilia And Flagella Associated Protein 77) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CFAP77 Gene

Genomics for CFAP77 Gene

Regulatory Elements for CFAP77 Gene

Promoters for CFAP77 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CFAP77 on UCSC Golden Path with GeneCards custom track

Genomic Location for CFAP77 Gene

Chromosome:
9
Start:
132,410,043 bp from pter
End:
132,573,319 bp from pter
Size:
163,277 bases
Orientation:
Plus strand

Genomic View for CFAP77 Gene

Genes around CFAP77 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CFAP77 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CFAP77 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CFAP77 Gene

Proteins for CFAP77 Gene

  • Protein details for CFAP77 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZQR2-CI171_HUMAN
    Recommended name:
    Uncharacterized protein C9orf171
    Protein Accession:
    Q6ZQR2
    Secondary Accessions:
    • Q147X1

    Protein attributes for CFAP77 Gene

    Size:
    320 amino acids
    Molecular mass:
    36499 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CFAP77 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CFAP77 Gene

Proteomics data for CFAP77 Gene at MOPED

Post-translational modifications for CFAP77 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CFAP77 Gene

No data available for DME Specific Peptides for CFAP77 Gene

Domains & Families for CFAP77 Gene

Protein Domains for CFAP77 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CFAP77: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CFAP77 Gene

Function for CFAP77 Gene

Phenotypes for CFAP77 Gene

GenomeRNAi human phenotypes for CFAP77:
genes like me logo Genes that share phenotypes with CFAP77: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CFAP77 Gene

Localization for CFAP77 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CFAP77 Gene

Pathways & Interactions for CFAP77 Gene

SuperPathways for CFAP77 Gene

No Data Available

Interacting Proteins for CFAP77 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000343290%0d%0a9606.ENSP00000346440%0d%0a
Selected Interacting proteins: Q6ZQR2-CI171_HUMAN ENSP00000343290 for CFAP77 Gene via UniProtKB STRING

Gene Ontology (GO) - Biological Process for CFAP77 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CFAP77 Gene

Drugs & Compounds for CFAP77 Gene

No Compound Related Data Available

Transcripts for CFAP77 Gene

mRNA/cDNA for CFAP77 Gene

(4) REFSEQ mRNAs :
(8) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CFAP77 Gene

No ASD Table

Relevant External Links for CFAP77 Gene

GeneLoc Exon Structure for
CFAP77
ECgene alternative splicing isoforms for
CFAP77

Expression for CFAP77 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for CFAP77 Gene

Orthologs for CFAP77 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CFAP77 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C11H9orf171 35
  • 89.91 (n)
  • 91.9 (a)
C9orf171 36
  • 82 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C9H9orf171 35
  • 89.24 (n)
  • 90.07 (a)
C9orf171 36
  • 63 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1700101E01Rik 35
  • 84.97 (n)
  • 88.11 (a)
Cfap77 16
1700101E01Rik 36
  • 80 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C9H9orf171 35
  • 99.48 (n)
  • 100 (a)
C9orf171 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1564114 35
  • 83.86 (n)
  • 85.16 (a)
oppossum
(Monodelphis domestica)
Mammalia C9orf171 36
  • 70 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C9orf171 36
  • 37 (a)
OneToOne
chicken
(Gallus gallus)
Aves C17H9ORF171 35
  • 61.95 (n)
  • 52.79 (a)
C9orf171 36
  • 50 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100491608 35
  • 59.04 (n)
  • 49.25 (a)
zebrafish
(Danio rerio)
Actinopterygii si:ch211-215c18.4 35
  • 50.21 (n)
  • 41.7 (a)
C5H9orf171 36
  • 39 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea CSA.4401 36
  • 42 (a)
OneToOne
Species with no ortholog for CFAP77:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CFAP77 Gene

ENSEMBL:
Gene Tree for CFAP77 (if available)
TreeFam:
Gene Tree for CFAP77 (if available)

Paralogs for CFAP77 Gene

No data available for Paralogs for CFAP77 Gene

Variants for CFAP77 Gene

Sequence variations from dbSNP and Humsavar for CFAP77 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs494081 -- 132,494,624(-) gcctg(C/T)ccgat intron-variant
rs494839 -- 132,463,773(+) GGCAA(C/G)GGGGA intron-variant
rs498495 -- 132,463,399(+) TATGG(C/T)ACATC intron-variant
rs502742 -- 132,481,045(-) aactg(C/G)atgtg intron-variant
rs503623 -- 132,447,628(+) CACAG(C/G)GTGTC intron-variant

Variation tolerance for CFAP77 Gene

Residual Variation Intolerance Score: 77.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.92; 89.82% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CFAP77 Gene

HapMap Linkage Disequilibrium report
CFAP77

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CFAP77 Gene

Disorders for CFAP77 Gene

Relevant External Links for CFAP77

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CFAP77
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CFAP77

No disorders were found for CFAP77 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CFAP77 Gene

Publications for CFAP77 Gene

  1. The lung-specific proteome defined by integration of transcriptomics and antibody-based profiling. (PMID: 25169055) Lindskog C. … Micke P. (FASEB J. 2014) 2 3 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3

Products for CFAP77 Gene

Sources for CFAP77 Gene

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