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Aliases for CFAP73 Gene

Aliases for CFAP73 Gene

  • Cilia And Flagella Associated Protein 73 2 3 5
  • Coiled-Coil Domain Containing 42B 2 3
  • CCDC42B 3 4
  • MIA2 3

External Ids for CFAP73 Gene

Previous HGNC Symbols for CFAP73 Gene

  • CCDC42B

Summaries for CFAP73 Gene

GeneCards Summary for CFAP73 Gene

CFAP73 (Cilia And Flagella Associated Protein 73) is a Protein Coding gene. An important paralog of this gene is CCDC42.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CFAP73 Gene

Genomics for CFAP73 Gene

Regulatory Elements for CFAP73 Gene

Enhancers for CFAP73 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CFAP73 on UCSC Golden Path with GeneCards custom track

Genomic Location for CFAP73 Gene

Chromosome:
12
Start:
113,149,181 bp from pter
End:
113,159,276 bp from pter
Size:
10,096 bases
Orientation:
Plus strand

Genomic View for CFAP73 Gene

Genes around CFAP73 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CFAP73 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CFAP73 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CFAP73 Gene

Proteins for CFAP73 Gene

  • Protein details for CFAP73 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NFT4-CC42B_HUMAN
    Recommended name:
    Coiled-coil domain-containing protein 42B
    Protein Accession:
    A6NFT4

    Protein attributes for CFAP73 Gene

    Size:
    308 amino acids
    Molecular mass:
    35914 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CFAP73 Gene

Proteomics data for CFAP73 Gene at MOPED

Post-translational modifications for CFAP73 Gene

No Post-translational modifications

Other Protein References for CFAP73 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CFAP73 Gene

Domains & Families for CFAP73 Gene

Protein Domains for CFAP73 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CFAP73 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NFT4

UniProtKB/Swiss-Prot:

CC42B_HUMAN :
  • Belongs to the CCDC42 family.
Family:
  • Belongs to the CCDC42 family.
genes like me logo Genes that share domains with CFAP73: view

No data available for Gene Families for CFAP73 Gene

Function for CFAP73 Gene

Phenotypes for CFAP73 Gene

GenomeRNAi human phenotypes for CFAP73:
genes like me logo Genes that share phenotypes with CFAP73: view

Animal Model Products

miRNA for CFAP73 Gene

miRTarBase miRNAs that target CFAP73

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CFAP73 Gene

Localization for CFAP73 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CFAP73 Gene

Pathways & Interactions for CFAP73 Gene

SuperPathways for CFAP73 Gene

No Data Available

Interacting Proteins for CFAP73 Gene

Gene Ontology (GO) - Biological Process for CFAP73 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CFAP73 Gene

Drugs & Compounds for CFAP73 Gene

No Compound Related Data Available

Transcripts for CFAP73 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for CFAP73 Gene

No ASD Table

Relevant External Links for CFAP73 Gene

GeneLoc Exon Structure for
CFAP73
ECgene alternative splicing isoforms for
CFAP73

Expression for CFAP73 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for CFAP73 Gene

Orthologs for CFAP73 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CFAP73 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia CCDC42B 35
  • 83.12 (n)
  • 80.19 (a)
CCDC42B 36
  • 79 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CCDC42B 35
  • 82.44 (n)
  • 75.5 (a)
CCDC42B 36
  • 72 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ccdc42b 35
  • 67.97 (n)
  • 53.92 (a)
Cfap73 16
Ccdc42b 36
  • 54 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia CCDC42B 35
  • 99.57 (n)
  • 99.35 (a)
CCDC42B 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ccdc42b 35
  • 68.87 (n)
  • 52.81 (a)
platypus
(Ornithorhynchus anatinus)
Mammalia CCDC42B 36
  • 38 (a)
OneToOne
chicken
(Gallus gallus)
Aves CCDC42B 35
  • 55.21 (n)
  • 41.7 (a)
CCDC42B 36
  • 38 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CCDC42B 36
  • 39 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii ccdc42b 36
  • 27 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.4208 36
  • 39 (a)
OneToMany
Species with no ortholog for CFAP73:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CFAP73 Gene

ENSEMBL:
Gene Tree for CFAP73 (if available)
TreeFam:
Gene Tree for CFAP73 (if available)

Paralogs for CFAP73 Gene

Paralogs for CFAP73 Gene

genes like me logo Genes that share paralogs with CFAP73: view

Variants for CFAP73 Gene

Sequence variations from dbSNP and Humsavar for CFAP73 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs7136744 -- 113,151,096(+) GGAAC(A/G)GGGAT intron-variant
rs12814210 -- 113,153,703(+) tcctc(C/G)tgcct intron-variant
rs12819915 -- 113,153,704(+) cctcc(G/T)gcctc intron-variant
rs7307978 -- 113,154,134(+) attag(C/T)cgggc intron-variant
rs34040669 -- 113,153,328(+) GGAAC(-/A)ACGCG reference, frameshift-variant

Variation tolerance for CFAP73 Gene

Gene Damage Index Score: 3.65; 56.81% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for CFAP73 Gene

Disorders for CFAP73 Gene

Relevant External Links for CFAP73

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CFAP73
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CFAP73

No disorders were found for CFAP73 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CFAP73 Gene

Publications for CFAP73 Gene

  1. The MIA complex is a conserved and novel dynein regulator essential for normal ciliary motility. (PMID: 23569216) Yamamoto R. … Sale W.S. (J. Cell Biol. 2013) 2 3 67
  2. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer S.E. … Gibbs R.A. (Nature 2006) 3

Products for CFAP73 Gene

Sources for CFAP73 Gene

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