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Aliases for CFAP69 Gene

Aliases for CFAP69 Gene

  • Cilia And Flagella Associated Protein 69 2 3 5
  • C7orf63 3 4
  • Flagellar Protein 69 Homolog (Chlamydomonas) 2
  • Chromosome 7 Open Reading Frame 63 2
  • Hypothetical Protein FLJ21062 2
  • FAP69 3

External Ids for CFAP69 Gene

Previous HGNC Symbols for CFAP69 Gene

  • C7orf63

Summaries for CFAP69 Gene

GeneCards Summary for CFAP69 Gene

CFAP69 (Cilia And Flagella Associated Protein 69) is a Protein Coding gene. GO annotations related to this gene include binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CFAP69 Gene

Genomics for CFAP69 Gene

Regulatory Elements for CFAP69 Gene

Promoters for CFAP69 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CFAP69 on UCSC Golden Path with GeneCards custom track

Genomic Location for CFAP69 Gene

Chromosome:
7
Start:
90,245,174 bp from pter
End:
90,324,208 bp from pter
Size:
79,035 bases
Orientation:
Plus strand

Genomic View for CFAP69 Gene

Genes around CFAP69 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CFAP69 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CFAP69 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CFAP69 Gene

Proteins for CFAP69 Gene

  • Protein details for CFAP69 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A5D8W1-CFA69_HUMAN
    Recommended name:
    Cilia- and flagella-associated protein 69
    Protein Accession:
    A5D8W1
    Secondary Accessions:
    • A3KMP9
    • B4DYW6
    • B4DZP7
    • B9EIM7
    • Q6V705
    • Q8IY89
    • Q9H7C2

    Protein attributes for CFAP69 Gene

    Size:
    941 amino acids
    Molecular mass:
    105883 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB14972.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for CFAP69 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CFAP69 Gene

Proteomics data for CFAP69 Gene at MOPED

Post-translational modifications for CFAP69 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CFAP69 Gene

Domains & Families for CFAP69 Gene

Protein Domains for CFAP69 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CFAP69: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CFAP69 Gene

Function for CFAP69 Gene

genes like me logo Genes that share phenotypes with CFAP69: view

Animal Models for CFAP69 Gene

MGI Knock Outs for CFAP69:

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for CFAP69 Gene

Localization for CFAP69 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CFAP69 Gene

Pathways & Interactions for CFAP69 Gene

SuperPathways for CFAP69 Gene

No Data Available

Interacting Proteins for CFAP69 Gene

Gene Ontology (GO) - Biological Process for CFAP69 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CFAP69 Gene

Drugs & Compounds for CFAP69 Gene

No Compound Related Data Available

Transcripts for CFAP69 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for CFAP69 Gene

No ASD Table

Relevant External Links for CFAP69 Gene

GeneLoc Exon Structure for
CFAP69
ECgene alternative splicing isoforms for
CFAP69

Expression for CFAP69 Gene

mRNA expression in normal human tissues for CFAP69 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for CFAP69 Gene

This gene is overexpressed in Plasma (56.1) and Brain (9.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CFAP69 Gene



genes like me logo Genes that share expression patterns with CFAP69: view

Protein tissue co-expression partners for CFAP69 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CFAP69 Gene

Orthologs for CFAP69 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CFAP69 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C4H7orf63 35
  • 90.55 (n)
  • 87.55 (a)
C7orf63 36
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C14H7orf63 35
  • 90.06 (n)
  • 88.77 (a)
C7orf63 36
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia A330021E22Rik 35
  • 84.7 (n)
  • 83.95 (a)
Cfap69 16
A330021E22Rik 36
  • 84 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C7H7orf63 35
  • 99.36 (n)
  • 98.94 (a)
C7orf63 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC100910867 35
  • 85.34 (n)
  • 83.81 (a)
oppossum
(Monodelphis domestica)
Mammalia C7orf63 36
  • 68 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C7orf63 36
  • 72 (a)
OneToOne
chicken
(Gallus gallus)
Aves C2H7ORF63 35
  • 67.94 (n)
  • 58.82 (a)
C7orf63 36
  • 57 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C7orf63 36
  • 62 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100494509 35
  • 64.72 (n)
  • 59.53 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 30 (a)
OneToMany
-- 36
  • 52 (a)
OneToMany
-- 36
  • 38 (a)
OneToMany
Species with no ortholog for CFAP69:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CFAP69 Gene

ENSEMBL:
Gene Tree for CFAP69 (if available)
TreeFam:
Gene Tree for CFAP69 (if available)

Paralogs for CFAP69 Gene

Pseudogenes.org Pseudogenes for CFAP69 Gene

genes like me logo Genes that share paralogs with CFAP69: view

No data available for Paralogs for CFAP69 Gene

Variants for CFAP69 Gene

Sequence variations from dbSNP and Humsavar for CFAP69 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs17862129 - 90,245,490(+) TCTAG(A/C/T)AGTTC nc-transcript-variant, reference, missense
rs17866223 - 90,274,042(+) ATGAC(C/T)GTCAG nc-transcript-variant, reference, missense
rs17865959 - 90,282,895(+) AGATC(C/T)GTTTT nc-transcript-variant, reference, missense
rs1029365 - 90,282,987(+) GAGCC(A/G/T)TGGTC nc-transcript-variant, reference, missense
rs17865475 - 90,307,778(+) GGCCA(C/T)GCACA nc-transcript-variant, reference, missense

Variation tolerance for CFAP69 Gene

Residual Variation Intolerance Score: 78.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 12.63; 94.54% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CFAP69 Gene

HapMap Linkage Disequilibrium report
CFAP69

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CFAP69 Gene

Disorders for CFAP69 Gene

Relevant External Links for CFAP69

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CFAP69

No disorders were found for CFAP69 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CFAP69 Gene

Publications for CFAP69 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  4. DNA methylation profiles in diffuse large B-cell lymphoma and their relationship to gene expression status. (PMID: 18288132) Pike B.L. … Hacia J.G. (Leukemia 2008) 3
  5. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3

Products for CFAP69 Gene

Sources for CFAP69 Gene

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