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Aliases for CFAP58 Gene

Aliases for CFAP58 Gene

  • Cilia And Flagella Associated Protein 58 2 3
  • Coiled-Coil Domain-Containing Protein 147 3 4
  • Coiled-Coil Domain Containing 147 2 3
  • C10orf80 3 4
  • CCDC147 3 4
  • Cilia- And Flagella-Associated Protein 58 3
  • Chromosome 10 Open Reading Frame 80 2
  • BA127L20.4 (Novel Protein) 3
  • BA127L20.5 (Novel Protein) 3
  • BA127L20.4 3
  • BA127L20.5 3
  • BA554P13.1 3

External Ids for CFAP58 Gene

Previous HGNC Symbols for CFAP58 Gene

  • C10orf80
  • CCDC147

Summaries for CFAP58 Gene

GeneCards Summary for CFAP58 Gene

CFAP58 (Cilia And Flagella Associated Protein 58) is a Protein Coding gene. An important paralog of this gene is CCDC146.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CFAP58 Gene

Genomics for CFAP58 Gene

Genomic Location for CFAP58 Gene

104,353,764 bp from pter
104,455,090 bp from pter
101,327 bases
Plus strand

Genomic View for CFAP58 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CFAP58 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CFAP58 Gene

No data available for Regulatory Elements for CFAP58 Gene

Proteins for CFAP58 Gene

  • Protein details for CFAP58 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Cilia- and flagella-associated protein 58
    Protein Accession:
    Secondary Accessions:
    • D3DRA6
    • Q8NA27

    Protein attributes for CFAP58 Gene

    872 amino acids
    Molecular mass:
    103417 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CFAP58 Gene

Proteomics data for CFAP58 Gene at MOPED

Post-translational modifications for CFAP58 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CFAP58 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CFAP58 Gene

Domains for CFAP58 Gene

Protein Domains for CFAP58 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the CFAP58 family.
  • Belongs to the CFAP58 family.
genes like me logo Genes that share domains with CFAP58: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for CFAP58 Gene

Function for CFAP58 Gene

Gene Ontology (GO) - Molecular Function for CFAP58 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding --
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with CFAP58: view

miRNA for CFAP58 Gene

miRTarBase miRNAs that target CFAP58

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CFAP58

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for CFAP58 Gene

Localization for CFAP58 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CFAP58 Gene

Cell projection, cilium.

Gene Ontology (GO) - Cellular Components for CFAP58 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 23580065
GO:0005929 cilium IEA --
genes like me logo Genes that share ontologies with CFAP58: view

No data available for Subcellular locations from COMPARTMENTS for CFAP58 Gene

Pathways for CFAP58 Gene

SuperPathways for CFAP58 Gene

No Data Available

Interacting Proteins for CFAP58 Gene

Gene Ontology (GO) - Biological Process for CFAP58 Gene


No data available for Pathways by source for CFAP58 Gene

Transcripts for CFAP58 Gene

mRNA/cDNA for CFAP58 Gene

(4) REFSEQ mRNAs :
(12) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CFAP58

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CFAP58 Gene

No ASD Table

Relevant External Links for CFAP58 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CFAP58 Gene

mRNA expression in normal human tissues for CFAP58 Gene

Protein differential expression in normal tissues for CFAP58 Gene

This gene is overexpressed in Nasal epithelium (34.4), Lavage (17.2), and Platelet (7.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for CFAP58 Gene

genes like me logo Genes that share expressions with CFAP58: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Expression partners for CFAP58 Gene

Orthologs for CFAP58 Gene

This gene was present in the common ancestor of animals.

Orthologs for CFAP58 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CCDC147 35
  • 89.02 (n)
  • 91.21 (a)
CCDC147 36
  • 90 (a)
(Canis familiaris)
Mammalia CCDC147 35
  • 89.79 (n)
  • 90.4 (a)
CCDC147 36
  • 89 (a)
(Mus musculus)
Mammalia Ccdc147 35
  • 83.96 (n)
  • 87.62 (a)
Ccdc147 16
Ccdc147 36
  • 86 (a)
(Pan troglodytes)
Mammalia CCDC147 35
  • 99.46 (n)
  • 99.66 (a)
CCDC147 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Ccdc147 35
  • 84.36 (n)
  • 87.74 (a)
(Monodelphis domestica)
Mammalia CCDC147 36
  • 83 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 80 (a)
-- 36
  • 79 (a)
(Gallus gallus)
Aves CCDC147 35
  • 72.26 (n)
  • 68.79 (a)
CCDC147 36
  • 68 (a)
(Anolis carolinensis)
Reptilia CCDC147 36
  • 74 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc147 35
  • 72.31 (n)
  • 75.15 (a)
Str.17238 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.32243 35
(Danio rerio)
Actinopterygii ccdc147 35
  • 65.65 (n)
  • 65.01 (a)
Dr.18541 35
ccdc147 36
  • 62 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP003679 35
  • 47.14 (n)
  • 33.33 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG5882 35
  • 43.21 (n)
  • 27.15 (a)
CG5882 36
  • 23 (a)
CG6059 36
  • 19 (a)
Ory 36
  • 24 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.4096 35
sea squirt
(Ciona savignyi)
Ascidiacea CSA.9178 36
  • 63 (a)
Species with no ortholog for CFAP58:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CFAP58 Gene

Gene Tree for CFAP58 (if available)
Gene Tree for CFAP58 (if available)

Paralogs for CFAP58 Gene

Paralogs for CFAP58 Gene

genes like me logo Genes that share paralogs with CFAP58: view

Variants for CFAP58 Gene

Sequence variations from dbSNP and Humsavar for CFAP58 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs870753 -- 104,394,135(+) AGGAC(C/G)CTTTC intron-variant
rs914067 -- 104,377,428(+) GGTTA(C/T)GGCAG intron-variant
rs914068 -- 104,377,468(+) TTAAA(G/T)GTAGG intron-variant
rs1023122 -- 104,403,667(+) ATTAA(A/C)GATAG intron-variant
rs1109126 -- 104,384,219(-) ATGCA(C/T)ACAGA intron-variant

Relevant External Links for CFAP58 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CFAP58 Gene

Disorders for CFAP58 Gene

No disorders were found for CFAP58 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for CFAP58 Gene

Publications for CFAP58 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1. (PMID: 20811636) Giannone R.J. … Liu Y. (PLoS ONE 2010) 3
  5. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PMID: 21145461) Bennett E.J. … Harper J.W. (Cell 2010) 3

Products for CFAP58 Gene

Sources for CFAP58 Gene

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