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Aliases for CFAP54 Gene

Aliases for CFAP54 Gene

  • Cilia And Flagella Associated 54 2 3
  • C12orf55 3 4
  • C12orf63 3 4
  • Cilia- And Flagella-Associated Protein 54 3
  • Chromosome 12 Open Reading Frame 63 2
  • Chromosome 12 Open Reading Frame 55 2

External Ids for CFAP54 Gene

Previous Symbols for CFAP54 Gene

  • C12orf63
  • C12orf55

Summaries for CFAP54 Gene

GeneCards Summary for CFAP54 Gene

CFAP54 (Cilia And Flagella Associated 54) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CFAP54 Gene

Genomics for CFAP54 Gene

Genomic Location for CFAP54 Gene

Start:
96,489,571 bp from pter
End:
96,875,555 bp from pter
Size:
385,985 bases
Orientation:
Plus strand

Genomic View for CFAP54 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CFAP54 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CFAP54 Gene

No data available for Regulatory Elements for CFAP54 Gene

Proteins for CFAP54 Gene

  • Protein details for CFAP54 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96N23-CFA54_HUMAN
    Recommended name:
    Cilia- and flagella-associated protein 54
    Protein Accession:
    Q96N23
    Secondary Accessions:
    • E9PJL5
    • Q6ZTY8

    Protein attributes for CFAP54 Gene

    Size:
    3096 amino acids
    Molecular mass:
    351970 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC86439.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for CFAP54 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CFAP54 Gene

Proteomics data for CFAP54 Gene at MOPED

Post-translational modifications for CFAP54 Gene

No Post-translational modifications

Other Protein References for CFAP54 Gene

No data available for DME Specific Peptides for CFAP54 Gene

Domains for CFAP54 Gene

Protein Domains for CFAP54 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q96N23

UniProtKB/Swiss-Prot:

CFA54_HUMAN
Family:
  • Belongs to the CFAP54 family.:
    • Q96N23
genes like me logo Genes that share domains with CFAP54: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for CFAP54 Gene

Function for CFAP54 Gene

Gene Ontology (GO) - Molecular Function for CFAP54 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with CFAP54: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CFAP54 Gene

Localization for CFAP54 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CFAP54 Gene

Cytoplasm, cytoskeleton, cilium axoneme.

Gene Ontology (GO) - Cellular Components for CFAP54 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005856 cytoskeleton IEA --
GO:0005930 axoneme ISS --
genes like me logo Genes that share ontologies with CFAP54: view

No data available for Subcellular locations from COMPARTMENTS for CFAP54 Gene

Pathways for CFAP54 Gene

SuperPathways for CFAP54 Gene

No Data Available

Interacting Proteins for CFAP54 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000431759%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000431759 for CFAP54 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for CFAP54 Gene

None

No data available for Pathways by source for CFAP54 Gene

Transcripts for CFAP54 Gene

mRNA/cDNA for CFAP54 Gene

(35) REFSEQ mRNAs :
(8) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CFAP54 Gene

No ASD Table

Relevant External Links for CFAP54 Gene

GeneLoc Exon Structure for
CFAP54
ECgene alternative splicing isoforms for
CFAP54

Expression for CFAP54 Gene

mRNA expression in normal human tissues for CFAP54 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for CFAP54 Gene

genes like me logo Genes that share expressions with CFAP54: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CFAP54 Gene

Orthologs for CFAP54 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CFAP54 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C12H12orf63 35
  • 99.17 (n)
  • 98.92 (a)
C12orf55 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C12orf55 36
  • 78 (a)
OneToOne
LOC787705 35
  • 84.89 (n)
  • 79.04 (a)
dog
(Canis familiaris)
Mammalia C12orf55 36
  • 81 (a)
OneToOne
LOC102153340 35
  • 87.4 (n)
  • 82.49 (a)
mouse
(Mus musculus)
Mammalia 4930485B16Rik 35
  • 77.32 (n)
  • 74.82 (a)
Gm872 36
  • 70 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C12orf55 36
  • 65 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1565866 35
  • 76.39 (n)
  • 72.7 (a)
chicken
(Gallus gallus)
Aves C12orf55 36
  • 51 (a)
OneToOne
LOC417921 35
  • 60.91 (n)
  • 49.25 (a)
lizard
(Anolis carolinensis)
Reptilia C12orf55 36
  • 46 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100490177 35
  • 55.66 (n)
  • 43.92 (a)
zebrafish
(Danio rerio)
Actinopterygii C12orf55 36
  • 37 (a)
OneToOne
LOC100536124 35
  • 49.11 (n)
  • 39.76 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 44 (a)
OneToOne
Species with no ortholog for CFAP54:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CFAP54 Gene

ENSEMBL:
Gene Tree for CFAP54 (if available)
TreeFam:
Gene Tree for CFAP54 (if available)

Paralogs for CFAP54 Gene

No data available for Paralogs for CFAP54 Gene

Variants for CFAP54 Gene

Sequence variations from dbSNP and Humsavar for CFAP54 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs4012 -- 96,627,332(-) ACATA(C/T)ACAAA intron-variant
rs34478 -- 96,762,772(-) AAAAA(A/C/G)CCCTA intron-variant
rs34479 -- 96,761,912(-) cactt(C/T)acaat intron-variant
rs34480 -- 96,759,877(-) CATAA(C/T)GAGAA intron-variant
rs34481 -- 96,758,078(-) tctat(A/G)agagt intron-variant

Relevant External Links for CFAP54 Gene

HapMap Linkage Disequilibrium report
CFAP54

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CFAP54 Gene

Disorders for CFAP54 Gene

No disorders were found for CFAP54 Gene.

No data available for UniProtKB/Swiss-Prot for CFAP54 Gene

Publications for CFAP54 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer S.E. … Gibbs R.A. (Nature 2006) 3 4
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  4. Genome-wide association study of anthropometric traits and evidence of interactions with age and study year in Filipino women. (PMID: 20966902) Croteau-Chonka D.C. … Mohlke K.L. (Obesity (Silver Spring) 2011) 3
  5. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3

Products for CFAP54 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate CFAP54
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for CFAP54
    • Block miRNA regulation of CFAP54 using miScript Target Protectors

    Sources for CFAP54 Gene

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