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Aliases for CFAP54 Gene

Aliases for CFAP54 Gene

  • Cilia And Flagella Associated 54 2 3
  • C12orf55 3 4
  • C12orf63 3 4
  • Cilia- And Flagella-Associated Protein 54 3
  • Chromosome 12 Open Reading Frame 63 2
  • Chromosome 12 Open Reading Frame 55 2

External Ids for CFAP54 Gene

Previous HGNC Symbols for CFAP54 Gene

  • C12orf63
  • C12orf55

Summaries for CFAP54 Gene

GeneCards Summary for CFAP54 Gene

CFAP54 (Cilia And Flagella Associated 54) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CFAP54 Gene

Genomics for CFAP54 Gene

Genomic Location for CFAP54 Gene

96,489,571 bp from pter
96,875,555 bp from pter
385,985 bases
Plus strand

Genomic View for CFAP54 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CFAP54 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CFAP54 Gene

No data available for Regulatory Elements for CFAP54 Gene

Proteins for CFAP54 Gene

  • Protein details for CFAP54 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Cilia- and flagella-associated protein 54
    Protein Accession:
    Secondary Accessions:
    • E9PJL5
    • Q6ZTY8

    Protein attributes for CFAP54 Gene

    3096 amino acids
    Molecular mass:
    351970 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC86439.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for CFAP54 Gene


neXtProt entry for CFAP54 Gene

Proteomics data for CFAP54 Gene at MOPED

Post-translational modifications for CFAP54 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CFAP54 Gene

No data available for DME Specific Peptides for CFAP54 Gene

Domains for CFAP54 Gene

Protein Domains for CFAP54 Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the CFAP54 family.
  • Belongs to the CFAP54 family.
genes like me logo Genes that share domains with CFAP54: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for CFAP54 Gene

Function for CFAP54 Gene

Gene Ontology (GO) - Molecular Function for CFAP54 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with CFAP54: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CFAP54 Gene

Localization for CFAP54 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CFAP54 Gene

Cytoplasm, cytoskeleton, cilium axoneme.

Gene Ontology (GO) - Cellular Components for CFAP54 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005856 cytoskeleton IEA --
GO:0005930 axoneme ISS --
genes like me logo Genes that share ontologies with CFAP54: view

No data available for Subcellular locations from COMPARTMENTS for CFAP54 Gene

Pathways for CFAP54 Gene

SuperPathways for CFAP54 Gene

No Data Available

Interacting Proteins for CFAP54 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000431759 for CFAP54 Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for CFAP54 Gene


No data available for Pathways by source for CFAP54 Gene

Transcripts for CFAP54 Gene

mRNA/cDNA for CFAP54 Gene

(35) REFSEQ mRNAs :
(8) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CFAP54 Gene

No ASD Table

Relevant External Links for CFAP54 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CFAP54 Gene

mRNA expression in normal human tissues for CFAP54 Gene

Protein differential expression in normal tissues for CFAP54 Gene

This gene is overexpressed in Cervix (63.7).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for CFAP54 Gene

genes like me logo Genes that share expressions with CFAP54: view

Expression partners for CFAP54 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CFAP54 Gene

Orthologs for CFAP54 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CFAP54 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC787705 35
  • 84.89 (n)
  • 79.04 (a)
C12orf55 36
  • 78 (a)
(Canis familiaris)
Mammalia LOC102153340 35
  • 87.4 (n)
  • 82.49 (a)
C12orf55 36
  • 81 (a)
(Mus musculus)
Mammalia 4930485B16Rik 35
  • 77.32 (n)
  • 74.82 (a)
Gm872 36
  • 70 (a)
(Pan troglodytes)
Mammalia C12H12orf63 35
  • 99.17 (n)
  • 98.92 (a)
C12orf55 36
  • 99 (a)
(Rattus norvegicus)
Mammalia RGD1565866 35
  • 76.39 (n)
  • 72.7 (a)
(Ornithorhynchus anatinus)
Mammalia C12orf55 36
  • 65 (a)
(Gallus gallus)
Aves LOC417921 35
  • 60.91 (n)
  • 49.25 (a)
C12orf55 36
  • 51 (a)
(Anolis carolinensis)
Reptilia C12orf55 36
  • 46 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100490177 35
  • 55.66 (n)
  • 43.92 (a)
(Danio rerio)
Actinopterygii LOC100536124 35
  • 49.11 (n)
  • 39.76 (a)
C12orf55 36
  • 37 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 44 (a)
Species with no ortholog for CFAP54:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CFAP54 Gene

Gene Tree for CFAP54 (if available)
Gene Tree for CFAP54 (if available)

Paralogs for CFAP54 Gene

No data available for Paralogs for CFAP54 Gene

Variants for CFAP54 Gene

Sequence variations from dbSNP and Humsavar for CFAP54 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs4012 -- 96,627,332(-) ACATA(C/T)ACAAA intron-variant
rs34478 -- 96,762,772(-) AAAAA(A/C/G)CCCTA intron-variant
rs34479 -- 96,761,912(-) cactt(C/T)acaat intron-variant
rs34480 -- 96,759,877(-) CATAA(C/T)GAGAA intron-variant
rs34481 -- 96,758,078(-) tctat(A/G)agagt intron-variant

Relevant External Links for CFAP54 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CFAP54 Gene

Disorders for CFAP54 Gene

No disorders were found for CFAP54 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for CFAP54 Gene

Publications for CFAP54 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer S.E. … Gibbs R.A. (Nature 2006) 3 4
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  4. Genome-wide association study of anthropometric traits and evidence of interactions with age and study year in Filipino women. (PMID: 20966902) Croteau-Chonka D.C. … Mohlke K.L. (Obesity (Silver Spring) 2011) 3
  5. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3

Products for CFAP54 Gene

Sources for CFAP54 Gene

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