Aliases for CFAP43 Gene
Aliases for CFAP43 Gene
External Ids for CFAP43 Gene
- HGNC: 26684
- Entrez Gene: 80217
- Ensembl: ENSG00000197748
- UniProtKB: Q8NDM7
Previous HGNC Symbols for CFAP43 Gene
- C10orf79
- WDR96
Summaries for CFAP43 Gene
GeneCards Summary for CFAP43 Gene
CFAP43 (Cilia And Flagella Associated Protein 43) is a Protein Coding gene.
No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CFAP43 Gene
Genomics for CFAP43 Gene
Regulatory Elements for CFAP43 Gene
Enhancers for CFAP43 Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around CFAP43 on UCSC Golden Path with GeneCards custom track
Promoters for CFAP43 Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|
ENSRs around CFAP43 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for CFAP43 Gene
- Chromosome:
- 10
- Start:
- 104,129,888 bp from pter
- End:
- 104,232,366 bp from pter
- Size:
- 102,479 bases
- Orientation:
- Minus strand
Genomic View for CFAP43 Gene
Genes around CFAP43 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 10q25.1 by Ensembl
- 10q25.1 by Entrez Gene
- 10q25.1 by HGNC
CFAP43 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CFAP43 Gene
Proteins for CFAP43 Gene
-
Protein details for CFAP43 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8NDM7-CFA43_HUMAN
- Recommended name:
- Cilia- and flagella-associated protein 43
- Protein Accession:
- Q8NDM7
- Q8N9Z8
- Q8NE17
- Q9H085
- Q9H5W3
Protein attributes for CFAP43 Gene
- Size:
- 1665 amino acids
- Molecular mass:
- 191984 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAC04133.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAB66835.1; Type=Frameshift; Positions=34, 625, 849, 1232, 1348, 1351, 1460, 1473, 1524, 1577; Evidence={ECO:0000305}; Sequence=CAI17220.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI17221.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI40457.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Protein Expression for CFAP43 Gene
Post-translational modifications for CFAP43 Gene
Other Protein References for CFAP43 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Search GeneTex for Antibodies for CFAP43
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for CFAP43
- Origene Custom Protein Services for CFAP43
- Search GeneTex for Proteins for CFAP43
Assay Products
No data available for DME Specific Peptides for CFAP43 Gene
Domains & Families for CFAP43 Gene
Gene Families for CFAP43 Gene
Protein Domains for CFAP43 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for CFAP43 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q8NDM7- Family:
-
- Belongs to the CFAP43 family.
- Similarity:
-
- Contains 9 WD repeats.
Function for CFAP43 Gene
Phenotypes for CFAP43 Gene
- GenomeRNAi human phenotypes for CFAP43:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for CFAP43 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CFAP43 gene
- Search ViGene Biosciences for CFAP43
CRISPR Products
-
OriGene CRISPR knockouts for CFAP43
- GenScript: Design CRISPR guide RNA sequences for CFAP43
miRNA for CFAP43 Gene
- miRTarBase miRNAs that target CFAP43
miRNA Products
- Search ViGene Biosciences for CFAP43
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CFAP43
- Browse OriGene Inhibitory RNA Products For CFAP43
-
ViGene Biosciences ready-to-package AAV shRNAs for CFAP43 gene
Clone Products
- OriGene ORF clones in human for CFAP43
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for CFAP43 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CFAP43 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CFAP43 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CFAP43 Gene
Localization for CFAP43 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CFAP43 Gene
- Cell projection, cilium, flagellum.
No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CFAP43 Gene
Pathways & Interactions for CFAP43 Gene
More details on SuperPathways for CFAP43
No Data Available
Interacting Proteins for CFAP43 Gene
No data available for Pathways by source and SIGNOR curated interactions for CFAP43 Gene
Transcripts for CFAP43 Gene
mRNA/cDNA for CFAP43 Gene
- (11) REFSEQ mRNAs :
- (55) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for CFAP43
- GenScript: Design CRISPR guide RNA sequences for CFAP43
miRNA Products
- Search ViGene Biosciences for CFAP43
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CFAP43
- Browse OriGene Inhibitory RNA Products For CFAP43
-
ViGene Biosciences ready-to-package AAV shRNAs for CFAP43 gene
Clone Products
- OriGene ORF clones in human for CFAP43
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: |
| ExUns: | 22a | · | 22b | ^ | 23 | ^ | 24 | ^ | 25 | ^ | 26 | ^ | 27a | · | 27b | ^ | 28a | · | 28b | ^ | 29a | · | 29b | ^ | 30 | ^ | 31 | ^ | 32 | ^ | 33 | ^ | 34 | ^ | 35 | ^ | 36a | · | 36b | ^ | 37 | ^ | 38a | · | 38b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP2: | |||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||||||||||||||
| SP7: |
Expression for CFAP43 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
This gene is overexpressed in Bone marrow mesenchymal stem cell (40.3), Spinal cord (15.7), and Lung (8.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CFAP43 Gene
Primer Products
-
OriGene qPCR primer pairs for CFAP43
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for CFAP43 Gene
Orthologs for CFAP43 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | WDR96 35 |
|
||
| WDR96 36 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | WDR96 35 |
|
||
| WDR96 36 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Wdr96 35 |
|
||
| Cfap43 16 |
|
||||
| Wdr96 36 |
|
OneToOne | |||
| chimpanzee (Pan troglodytes) |
Mammalia | WDR96 35 |
|
||
| WDR96 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Wdr96 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | -- 36 |
|
OneToMany | |
| -- 36 |
|
OneToMany | |||
| -- 36 |
|
OneToMany | |||
| platypus (Ornithorhynchus anatinus) |
Mammalia | WDR96 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | WDR96 35 |
|
||
| WDR96 36 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | WDR96 36 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | wdr96 35 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | wdr96 35 |
|
||
| wdr96 36 |
|
OneToOne | |||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP003166 35 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG17687 36 |
|
OneToOne | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 36 |
|
OneToOne |
- Species with no ortholog for CFAP43:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for CFAP43 Gene
No data available for Paralogs for CFAP43 Gene
Variants for CFAP43 Gene
| SNP ID | Clin | Chr 10 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs10883979 | - | 104,197,956(+) | AGTCA(A/G)TTGCC | intron-variant, reference, missense | |
| rs35901897 | - | 104,187,334(-) | GCTAC(C/T)TTCTT | reference, missense | |
| rs17116635 | - | 104,186,084(+) | TTGTA(C/T)TTTTT | upstream-variant-2KB, reference, missense | |
| rs12262825 | - | 104,172,493(+) | TTTTG(A/C)AATAT | reference, missense | |
| rs1436925 | -- | 104,204,573(-) | TTATA(A/G)CATTT | intron-variant |
Residual Variation Intolerance Score:
73.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.29;
62.77% of all genes are more intolerant (likely to be disease-causing)
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for CFAP43 Gene
Disorders for CFAP43 Gene
Relevant External Links for CFAP43
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- CFAP43
No disorders were found for CFAP43 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CFAP43 Gene
Publications for CFAP43 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 2 3 4 67
- 14-3-3 epsilon dynamically interacts with key components of mitogen-activated protein kinase signal module for selective modulation of the TNF-alpha-induced time course-dependent NF-kappaB activity. (PMID: 20462248) Zuo S. … Chen X. (J. Proteome Res. 2010) 3
- Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PMID: 19913121) Talmud P.J. … . (Am. J. Hum. Genet. 2009) 3
- Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies. (PMID: 18839057) Lesch K.P. … Jacob C. (J Neural Transm 2008) 3
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
Products for CFAP43 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for CFAP43
- Origene Custom Protein Services for CFAP43
- Origene siRNA, shRNA, and RNAi products in human, mouse, rat for CFAP43
- Browse OriGene Inhibitory RNA Products For CFAP43
- OriGene qPCR primer pairs for CFAP43
- OriGene CRISPR knockouts for CFAP43
- OriGene ORF clones in human for CFAP43
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for CFAP43
- GenScript Custom Assay Services for CFAP43
- GenScript Custom overexpressing Cell Line Services for CFAP43
- GenScript: Design CRISPR guide RNA sequences for CFAP43
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for CFAP43
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ViGene Biosciences adenoviral particle packaged cDNA for CFAP43 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CFAP43 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CFAP43 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CFAP43 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CFAP43 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CFAP43 gene
- Search ViGene Biosciences for CFAP43
- Search ViGene Biosciences for CFAP43
Sources for CFAP43 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
- (127) FDA Approved Drugs
- (128) RVIS
- (129) SIGNOR
- (130) diseasecard
- (131) NIH Rare Diseases
- (132) Orphanet
- (133) UMLS
- (134) GTR
- (135) Disease Ontology
- (136) Genetics Home Reference
- (137) MeSH
- (138) MedlinePlus
- (139) CDC
- (140) NINDS
- (141) NCBI Bookshelf
- (142) ClinVar
- (143) Gene Damage Index
- (144) ViGene Biosciences
- (145) HPO
- (146) UDN
- (147) VISTA
- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon