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Aliases for CFAP36 Gene

Aliases for CFAP36 Gene

  • Cilia And Flagella Associated Protein 36 2 3 5
  • Coiled-Coil Domain-Containing Protein 104 3 4
  • Coiled-Coil Domain Containing 104 2 3
  • CCDC104 3 4

External Ids for CFAP36 Gene

Previous HGNC Symbols for CFAP36 Gene

  • CCDC104

Summaries for CFAP36 Gene

GeneCards Summary for CFAP36 Gene

CFAP36 (Cilia And Flagella Associated Protein 36) is a Protein Coding gene.

UniProtKB/Swiss-Prot for CFAP36 Gene

  • May act as an effector for ARL3.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CFAP36 Gene

Genomics for CFAP36 Gene

Regulatory Elements for CFAP36 Gene

Enhancers for CFAP36 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CFAP36 on UCSC Golden Path with GeneCards custom track

Promoters for CFAP36 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CFAP36 on UCSC Golden Path with GeneCards custom track

Genomic Location for CFAP36 Gene

55,519,595 bp from pter
55,545,879 bp from pter
26,285 bases
Plus strand

Genomic View for CFAP36 Gene

Genes around CFAP36 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CFAP36 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CFAP36 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CFAP36 Gene

Proteins for CFAP36 Gene

  • Protein details for CFAP36 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Cilia- and flagella-associated protein 36
    Protein Accession:
    Secondary Accessions:
    • Q53SF0
    • Q53ST9
    • Q6UY34

    Protein attributes for CFAP36 Gene

    342 amino acids
    Molecular mass:
    39447 Da
    Quaternary structure:
    • Interacts with ARL3.

    Alternative splice isoforms for CFAP36 Gene


neXtProt entry for CFAP36 Gene

Proteomics data for CFAP36 Gene at MOPED

Post-translational modifications for CFAP36 Gene

  • Ubiquitination at Lys 63, Lys 70, Lys 89, Lys 110, Lys 116, Lys 155, Lys 282, Lys 293, Lys 303, Lys 334, and Lys 336
  • Modification sites at PhosphoSitePlus

Other Protein References for CFAP36 Gene

No data available for DME Specific Peptides for CFAP36 Gene

Domains & Families for CFAP36 Gene

Protein Domains for CFAP36 Gene


Suggested Antigen Peptide Sequences for CFAP36 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the CFAP36 family.
  • Belongs to the CFAP36 family.
genes like me logo Genes that share domains with CFAP36: view

No data available for Gene Families for CFAP36 Gene

Function for CFAP36 Gene

Molecular function for CFAP36 Gene

UniProtKB/Swiss-Prot Function:
May act as an effector for ARL3.
genes like me logo Genes that share phenotypes with CFAP36: view

Animal Models for CFAP36 Gene

MGI Knock Outs for CFAP36:

Animal Model Products

miRNA for CFAP36 Gene

miRTarBase miRNAs that target CFAP36

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CFAP36 Gene

Localization for CFAP36 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CFAP36 Gene

Nucleus. Cytoplasm. Cell projection, cilium, flagellum.

Gene Ontology (GO) - Cellular Components for CFAP36 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0042995 cell projection IEA --
genes like me logo Genes that share ontologies with CFAP36: view

No data available for Subcellular locations from COMPARTMENTS for CFAP36 Gene

Pathways & Interactions for CFAP36 Gene

SuperPathways for CFAP36 Gene

No Data Available

Interacting Proteins for CFAP36 Gene

Gene Ontology (GO) - Biological Process for CFAP36 Gene


No data available for Pathways by source and SIGNOR curated interactions for CFAP36 Gene

Drugs & Compounds for CFAP36 Gene

No Compound Related Data Available

Transcripts for CFAP36 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for CFAP36 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b ^ 12
SP1: - - - -
SP2: - - - - -
SP3: -
SP4: - - -
SP5: -
SP6: - - -

Relevant External Links for CFAP36 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CFAP36 Gene

mRNA expression in normal human tissues for CFAP36 Gene

Protein differential expression in normal tissues from HIPED for CFAP36 Gene

This gene is overexpressed in Testis (10.8), Fetal Brain (8.7), Ovary (8.2), Gallbladder (7.2), CD8 Tcells (6.5), and Fetal ovary (6.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CFAP36 Gene

mRNA Expression by UniProt/SwissProt for CFAP36 Gene

Tissue specificity: Expressed in several human tissues including brain, testis, heart, lung, pancreas and spleen (at protein level).
genes like me logo Genes that share expression patterns with CFAP36: view

Protein tissue co-expression partners for CFAP36 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for CFAP36 Gene

Orthologs for CFAP36 Gene

This gene was present in the common ancestor of animals.

Orthologs for CFAP36 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CCDC104 35
  • 91.91 (n)
  • 91.37 (a)
CCDC104 36
  • 91 (a)
(Canis familiaris)
Mammalia CCDC104 35
  • 93.7 (n)
  • 92.68 (a)
CCDC104 36
  • 87 (a)
(Mus musculus)
Mammalia Ccdc104 35
  • 88.5 (n)
  • 90.94 (a)
Cfap36 16
Ccdc104 36
  • 91 (a)
(Pan troglodytes)
Mammalia CCDC104 35
  • 99.61 (n)
  • 99.12 (a)
CCDC104 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Ccdc104 35
  • 87.33 (n)
  • 90.06 (a)
(Monodelphis domestica)
Mammalia CCDC104 36
  • 72 (a)
(Ornithorhynchus anatinus)
Mammalia CCDC104 36
  • 70 (a)
(Gallus gallus)
Aves CCDC104 35
  • 66.25 (n)
  • 58.31 (a)
CCDC104 36
  • 54 (a)
(Anolis carolinensis)
Reptilia CCDC104 36
  • 61 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ccdc104 35
  • 61.72 (n)
  • 52.26 (a)
MGC76095 35
African clawed frog
(Xenopus laevis)
Amphibia mgc15407-prov 35
(Danio rerio)
Actinopterygii ccdc104 35
  • 52.87 (n)
  • 49.34 (a)
ccdc104 36
  • 39 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG14367 36
  • 26 (a)
(Caenorhabditis elegans)
Secernentea Y108G3AL.3 36
  • 12 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2835 36
  • 17 (a)
Species with no ortholog for CFAP36:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CFAP36 Gene

Gene Tree for CFAP36 (if available)
Gene Tree for CFAP36 (if available)

Paralogs for CFAP36 Gene

No data available for Paralogs for CFAP36 Gene

Variants for CFAP36 Gene

Sequence variations from dbSNP and Humsavar for CFAP36 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1045910 - 55,544,025(+) AAAAG(A/G)CCTGA reference, missense
rs1045920 - 55,544,033(+) TGAAG(A/G/T)TTCCT reference, missense
rs34891804 - 55,519,819(-) TCGTC(G/T)TCTTC reference, missense
rs1867334 -- 55,533,469(+) TAGGC(C/T)GAGGG intron-variant
rs3030733 -- 55,541,849(+) TCGTA(-/GATA)CTCTT intron-variant

Variation tolerance for CFAP36 Gene

Residual Variation Intolerance Score: 47.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.76; 78.90% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for CFAP36 Gene

Disorders for CFAP36 Gene

Relevant External Links for CFAP36

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CFAP36 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CFAP36 Gene

Publications for CFAP36 Gene

  1. Antibody to CCDC104 is associated with a paraneoplastic antibody to CDR2 (anti-Yo). (PMID: 19680650) Totland C. … Vedeler C.A. (Cancer Immunol. Immunother. 2010) 2 3 4 67
  2. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3
  3. A human MAP kinase interactome. (PMID: 20936779) Bandyopadhyay S. … Ideker T. (Nat. Methods 2010) 3
  4. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  5. Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach. (PMID: 18654987) Thalappilly S. … Dusetti N.J. (Proteomics 2008) 3

Products for CFAP36 Gene

Sources for CFAP36 Gene