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Aliases for CFAP157 Gene

Aliases for CFAP157 Gene

  • Cilia And Flagella Associated Protein 157 2 3 5
  • C9orf117 3 4
  • Chromosome 9 Open Reading Frame 117 2

External Ids for CFAP157 Gene

Previous HGNC Symbols for CFAP157 Gene

  • C9orf117

Summaries for CFAP157 Gene

GeneCards Summary for CFAP157 Gene

CFAP157 (Cilia And Flagella Associated Protein 157) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CFAP157 Gene

Genomics for CFAP157 Gene

Regulatory Elements for CFAP157 Gene

Enhancers for CFAP157 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CFAP157 on UCSC Golden Path with GeneCards custom track

Genomic Location for CFAP157 Gene

Chromosome:
9
Start:
127,706,988 bp from pter
End:
127,716,002 bp from pter
Size:
9,015 bases
Orientation:
Plus strand

Genomic View for CFAP157 Gene

Genes around CFAP157 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CFAP157 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CFAP157 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CFAP157 Gene

Proteins for CFAP157 Gene

  • Protein details for CFAP157 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5JU67-CI117_HUMAN
    Recommended name:
    Uncharacterized protein C9orf117
    Protein Accession:
    Q5JU67
    Secondary Accessions:
    • A5D8T9

    Protein attributes for CFAP157 Gene

    Size:
    520 amino acids
    Molecular mass:
    60533 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CFAP157 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CFAP157 Gene

Proteomics data for CFAP157 Gene at MOPED

Post-translational modifications for CFAP157 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CFAP157 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CFAP157 Gene

Domains & Families for CFAP157 Gene

Protein Domains for CFAP157 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CFAP157: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CFAP157 Gene

Function for CFAP157 Gene

genes like me logo Genes that share phenotypes with CFAP157: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CFAP157 Gene

Localization for CFAP157 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CFAP157 Gene

Pathways & Interactions for CFAP157 Gene

SuperPathways for CFAP157 Gene

No Data Available

Interacting Proteins for CFAP157 Gene

Gene Ontology (GO) - Biological Process for CFAP157 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CFAP157 Gene

Drugs & Compounds for CFAP157 Gene

No Compound Related Data Available

Transcripts for CFAP157 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for CFAP157 Gene

No ASD Table

Relevant External Links for CFAP157 Gene

GeneLoc Exon Structure for
CFAP157
ECgene alternative splicing isoforms for
CFAP157

Expression for CFAP157 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for CFAP157 Gene

Orthologs for CFAP157 Gene

This gene was present in the common ancestor of animals.

Orthologs for CFAP157 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C11H9orf117 35
  • 81.88 (n)
  • 71.18 (a)
C9orf117 36
  • 71 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C9H9orf117 35
  • 81.88 (n)
  • 75.53 (a)
C9orf117 36
  • 71 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1700019L03Rik 35
  • 77.17 (n)
  • 65.95 (a)
Cfap157 16
1700019L03Rik 36
  • 64 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C9H9orf117 35
  • 99.1 (n)
  • 98.46 (a)
C9orf117 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC499781 35
  • 76.41 (n)
  • 66.47 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 56 (a)
OneToMany
-- 36
  • 33 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia C9orf117 36
  • 58 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c9orf117 35
  • 55.8 (n)
  • 46.26 (a)
zebrafish
(Danio rerio)
Actinopterygii si:ch211-233f10.4 35
  • 51.41 (n)
  • 38.8 (a)
C5H9orf117 36
  • 36 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG17122 36
  • 17 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 36 (a)
OneToOne
Species with no ortholog for CFAP157:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CFAP157 Gene

ENSEMBL:
Gene Tree for CFAP157 (if available)
TreeFam:
Gene Tree for CFAP157 (if available)

Paralogs for CFAP157 Gene

No data available for Paralogs for CFAP157 Gene

Variants for CFAP157 Gene

Sequence variations from dbSNP and Humsavar for CFAP157 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs7848745 -- 127,707,656(+) aagtg(A/G)ggaag intron-variant
rs7849115 -- 127,707,896(+) TGGGT(A/G)ACCAC intron-variant
rs7849124 -- 127,707,921(+) CCCTC(A/G)TGGTG intron-variant
rs7849125 -- 127,707,924(+) TCGTG(A/G)TGCCA intron-variant
rs1756008 -- 127,706,294(+) GCCCC(C/T)GCCCC upstream-variant-2KB

Variation tolerance for CFAP157 Gene

Residual Variation Intolerance Score: 87.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.02; 50.09% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for CFAP157 Gene

Disorders for CFAP157 Gene

Relevant External Links for CFAP157

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CFAP157
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CFAP157

No disorders were found for CFAP157 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CFAP157 Gene

Publications for CFAP157 Gene

  1. Transcriptional program of ciliated epithelial cells reveals new cilium and centrosome components and links to human disease. (PMID: 23300604) Hoh R.A. … Stearns T. (PLoS ONE 2012) 2 3 67
  2. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PMID: 21145461) Bennett E.J. … Harper J.W. (Cell 2010) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for CFAP157 Gene

Sources for CFAP157 Gene

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